Esteroides y derivados
Los esteroides son compuestos orgánicos que poseen una estructura de cuatro anillos fusionados, conocida como el núcleo esteroídico. Este núcleo puede unirse a varios grupos funcionales que modifican sus propiedades y funciones biológicas. Los esteroides tienen un papel clave en la regulación de procesos metabólicos y hormonales. Se utilizan en medicina para tratar trastornos inflamatorios, autoinmunes y desequilibrios hormonales. Además, algunos derivados esteroides tienen propiedades antiinflamatorias potentes, como los corticosteroides. En terapias específicas, se usan para reducir la inflamación y controlar el dolor en diversas enfermedades.
En CymitQuimica contamos con una variedad de esteroides y sus derivados para investigación y desarrollo farmacéutico.
Se han encontrado 4967 productos de "Esteroides y derivados"
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2,3-Dichloro-5,6-dicyanobenzoquinone
CAS:<p>Applications An oxidizing agent, especially in steroid synthesis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>Fórmula:C8Cl2N2O2Forma y color:NeatPeso molecular:227.0Tetrahydrodehydrocorticosterone
CAS:Producto controlado<p>Applications Tetrahydrodehydrocorticosterone inhibits aldosteronogenesis by intact cells at concentrations that inhibited angiotensin binding.<br>References Campanile, C.P., Goodfriend, T.L.: Steroids, 37, 681(1981)<br></p>Fórmula:C21H32O4Forma y color:NeatPeso molecular:348.48(17a)-3-Ethynyl-19-norpregna-3,5-dien-20-yn-17-ol
CAS:<p>Impurity Norethindrone EP Impurity E<br>Applications (17α)-3-Ethynyl-19-norpregna-3,5-dien-20-yn-17-ol (Norethindrone EP Impurity E) is an impurity of Norethindrone (N676000).<br></p>Fórmula:C22H26OForma y color:NeatPeso molecular:306.443β-Hydroxy Tibolone
CAS:Producto controlado<p>Applications A metabolite of Tibolone. A synthetic steroid with weak estrogenic, androgenic and progestogenic activity. A pharamceutical used in the treatment of menopausal syndrome.<br>References Belman, S., et al.: Cancer Res., 32, 450 (1972), Shirahashi, H., et al.: Chem. Pharm. Bull., 41, 1664 (1993), Hoyte, R., et al.: Steroids, 58, 13 (1993), Sandker, G., et al.: Xenobiotica, 24, 143 (1994), Colombo, D., et al.: Eur. J. Med. Chem., 40, 69 (2005),<br></p>Fórmula:C21H30O2Forma y color:White To Off-WhitePeso molecular:314.46Eplerenone 7-Carboxylic Acid
CAS:<p>Applications Eplerenone 7-Carboxylic Acid is an impurity of Eplerenone (E588775). Eplerenone is a selective aldosterone receptor antagonist (SARA), structurally similar to Spiranolactone. Eplerenone is used alone or in combination with other medications to treat high blood pressure. Eplerenone is in a class of medications called mineralocorticoid receptor antagonists. It works by blocking the action of aldosterone, a natural substance in the body that raises blood pressure.<br>References de Gasparo, M., et al.: J. Pharmacol. Exp. Ther., 240, 650 (1987), Delyani, J.A., et al.: Cardiovasc. Drug Rev., 19, 185 (2001), Burgess, E., et al.: Expert. Opin. Pharmacother., 5, 2573 (2004), Ravis, W.R., et al.: J. Clin. Pharmacol., 45, 810 (2005),<br></p>Fórmula:C23H28O6Forma y color:Off-White To Light YellowPeso molecular:400.46Estradiol Acetate
CAS:<p>Applications Estradiol acetate is used a reactant in the preparation of a modifier conjugate through a physiologically cleavable bond for enhanced drug transport across membranes.<br>References Hale, R., et al.: PCT Int. Appl. (1993), WO 9325197 A1 19931223.<br></p>Fórmula:C20H26O3Forma y color:NeatPeso molecular:314.423,3-Dimethoxyestra-5(10),9(11)-dien-17-one
CAS:<p>Applications 3,3-Dimethoxyestra-5(10),9(11)-dien-17-one, can be used for the synthesis of Trenbolone Acetate (T719080).<br>References Zhang, H., et al.: Fudan Xuebao, Yixueban, 29 (3), 211 (2002);<br></p>Fórmula:C20H28O3Forma y color:NeatPeso molecular:316.4321-Dehydro Betamethasone (mixture of the aldehyde and the hydrated form)
CAS:Producto controlado<p>Applications 21-Dehydro Betamethasone is an impurity of Betamethasone (B327000), a corticosteroid used as an anti-inflammatory agent.<br>References Chen, B., et al.: Steroids, 74, 30 (2009); Li, M., et al.: J. Pharm. Sci., 98, 894 (2009); Xiong, Y., et al.: J. Pharm. Biomed. Anal., 49, 646 (2009);<br></p>Fórmula:C22H27FO5Forma y color:NeatPeso molecular:390.45Norethindrone Acetate
CAS:<p>Applications Progesteron. Norethindrone and acetate in combination with estrogen as contraceptive (oral). It is reasonably anticipated to be a human carcinogen.<br>References Schroff, A. P., et al.: Anal. Profiles Drug Subs., 4, 268 (1975), Singh, H., et al.: Am. J. Obstet. Gynecol., 135, 409 (1979), Toews, M., et al.: Curr. Ther. Res, 41, 509 (1987),<br></p>Fórmula:C22H28O3Forma y color:White To Off-WhitePeso molecular:340.46Tetrahydrocortisol
CAS:Producto controlado<p>Applications Tetrahydrocortisol is excreted in large amounts in premenopausal patients with early breast cancer. Tetrahydrocortisol has been found to be produced by lymphocytes in both normal and cancer bearing patients however, the concentration of Tetrahydrocortisol has increased in patients with cancer.<br>References Kodama, M., et. al.: J. Natl. Cancer I., 54, 1275 (1975); Klein, A., et. al.: Metabolism, 27, 731 (1978)<br></p>Fórmula:C21H34O5Forma y color:Off-WhitePeso molecular:366.49Alphadolone
CAS:Producto controlado<p>Applications Alphadolone or Alfadolone (INN) is a neuroactive steroid with hypnotic effects. Alphadolone is one of the components of Althesin.<br>References Harrison, N., et al.: J. Pharmacol. Exp. Ther., 241, 346 (1987), Serrao, J., et al.: Anesthesiology, 70, 780 (1989), Mistry, D., et al.: Exp. Physiol., 75, 199 (1900),<br></p>Fórmula:C21H32O4Forma y color:NeatPeso molecular:348.48Algestone
CAS:Producto controlado<p>Applications A pregnane steroid, its acetonide is used as anti-inflammatory drug (topical) and combination with enanthate as injectable contraceptive.<br>References Hydorn, A., et al.: Steroids, 3, 493 (1964), Plesner, R., et al.: Acta Endorcinol., 61, 494 (1969),<br></p>Fórmula:C21H30O4Forma y color:NeatPeso molecular:346.4617a-Dihydro Equilenin
CAS:Producto controlado<p>Applications The 17α-metabolite of Equilin (E592800).<br>References Enmark, E., et al.: J. Clin. Endocrinol. Metab., 82, 4258 (1997), Wang, Z., et al.: J. Med. Chem., 43, 2419 (2000), Jiang, X., et al.: Steroids, 71, 334 (2006),<br></p>Fórmula:C18H20O2Forma y color:NeatPeso molecular:268.35Cortisol 21-Sulfate Potassium Salt
CAS:Producto controlado<p>Applications Cortisol 21-Sulfate is a phase II metabolite of Cortisol (H714615).<br>References Spielgelhalder, B., et al.: J. Steroid Biochem., 7, 749 (1976), Vanluchene, E., et al.: J. Chromatogr., 456, 175 (1988), Choi, M., et al.: Steroids, 65, 54 (2000),<br></p>Fórmula:C21H29KO8SForma y color:NeatPeso molecular:480.616a,9a-Difluoroprednisolone 21-Acetate
CAS:Producto controlado<p>Applications 6α,9α-Difluoroprednisolone 21-Acetate, is an impurity of Difluprednate (D445925), which is shown to have antiinflammatory activity.<br>References Toscano L., et al.: J. Med. chem., 20, 213 (1977);<br></p>Fórmula:C23H28F2O6Forma y color:White To Off-WhitePeso molecular:438.466-Keto Fulvestrant
<p>Applications Fulvestrant (F862500) impurity F.<br></p>Fórmula:C32H45F5O4SForma y color:NeatPeso molecular:620.75Testosterone-16,16,17-d3
CAS:Producto controlado<p>Applications Labelled Testosterone (T155000). Principal hormone of the testes, produced by the interstitial cells. Major circulating androgen; converted by 5α-reductase in androgen-dependent target tissues to 5α-dehydrotestosterone which is required for normal male sexual differentiation. Also converted by aromatization to Estradiol.Controlled substance (anabolic steroid). Androgen.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References McFarland, K., et al.: Science, 245, 494 (1989), Heckert, L., et al.: Mol. Endocrinol., 12, 1499 (1998), Themmen, A., et al.: Endocr. Rev. 21, 551 (2000), Kumar, R., et al.: Biol. Reprod., 65, 710 (2001),<br></p>Fórmula:C192H3H25O2Forma y color:NeatPeso molecular:291.44Clobetasol 17-Propionate
CAS:Producto controlado<p>Applications Topical corticosteroid. Glucocorticoid; anti-inflammatory.<br>References Olsen, E.A., et al.: J. Am. Acad. Dermatol., 15, 246 (1986),<br></p>Fórmula:C25H32ClFO5Forma y color:White To Off-WhitePeso molecular:466.976-Bromo-betamethasone 17,21-Dipropionate
CAS:Producto controlado<p>Stability Hygroscopic<br>Applications 6-Bromo-Betamethasone 17,21-Dipropionate (Betamethasone Dipropionate EP Impurity H) is an impurity of Betamethasone (B327000), a glucocorticoid used as an anti-inflammatory agent.<br>References Ferrante, M.G., et al.: Anal. Profiles Drug Subs., 6, 43 (1977); Li, A., et al.: Chem. Biol. Interact., 142, 7 (2002); Cruz-Monteagudo, M., et al.: Eur. J. Med. Chem., 40, 1030 (2005)<br></p>Fórmula:C28H36BrFO7Forma y color:NeatPeso molecular:583.48Tachysterol (>90%)
CAS:<p>Stability Light Sensitive, Temperature Sensitive<br>Applications Bioactive, synthetic vitamin D3 analog; exhibits antiproliferative effect on keratinocytes. Antipsoriatic.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Matsunaga, T., et al.: J. Dermatol., 17, 135 (1990), Gerritsen, M.J.P., et al.: Br. J. Dermatol., 131, 57 (1994),<br></p>Fórmula:C28H44OPureza:>90%Forma y color:NeatPeso molecular:396.65Glycine, N-[(3α,5β,7α,12α)-3,7,12-trihydroxy-24-oxocholan-24-yl]-, monosodium salt, monohydrate
CAS:Pureza:97%Peso molecular:505.628δ1-Adrenosterone
CAS:Producto controlado<p>Applications Δ1-Adrenosterone is a derivative of Adrenosterone (A305600), and is suspected to have some inhibitory effects on estrogen biosynthesis in human placental microsomes. Δ1-Adrenosterone also has potential androgenic anabolic and antiuterotropic activity.<br>References Lodge, B., et al.: Can. J. Pharm. Sci., 10, 107 (1975); Lodge, B., et al.: Can. J. Pharm. Sci., 11, 95 (1976); Schwarzel, W., et al.: Endocrinology, 92, 866 (1973)<br></p>Fórmula:C19H22O3Forma y color:NeatPeso molecular:298.386b-Bromo Androstenedione
CAS:Producto controlado<p>Applications Androstenedione (A637550) analog, an aromatase inhibitor.<br>References Marsh, D.A., et al.: J. Med. Chem., 28, 788 (1985),<br></p>Fórmula:C19H25BrO2Forma y color:NeatPeso molecular:365.30Equilenin
CAS:<p>Applications Equilenin is a naturally occuring estrogenic steroidal hormone (1,2) isolated from urine of pregnant mares (3). Not found in human urine. Component of conjugated estrogenic hormones. Estrogen. This compound is a contaminant of emerging concern (CECs). Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA), environmental, and food contaminants.<br>References 1. Corbellini, A. et L.: Farmaco Sci. 1964 Nov;19:913-22.2. Stein, R. et al.: Tetrahedron 1970 Apr;26(8):1917-33.3. Nett, T. et al.: J. Reprod. Fertil. Suppl. 1975 Oct;(23):457-62.<br></p>Fórmula:C18H18O2Forma y color:Light Beige To Light YellowPeso molecular:266.33di(2-Hydroxy Atorvastatin-d5) Calcium Salt
CAS:Producto controlado<p>Applications di(2-Hydroxy Atorvastatin-d5) Calcium Salt is the labeled analogue of di(2-Hydroxy Atorvastatin) Calcium Salt (H828930), a metabolite of Atorvastatin Calcium Salt (A791750), a selective, competitive HMG-CoA reductase inhibitor. Atorvastatin is the only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglycerides in patients with hypercholesterolemia.<br>References Kearney, A.S., et al.: Pharm. Res., 10, 1461 (1993); Heinonen, T.M., et al.: Clin. Ther., 18, 853 (1996); Whitfield, L.R., et al.: Eur. J. Drug Metab. Pharmacokinet., 25, 97 (2000)<br></p>Fórmula:C66H58D10CaF2N4O12Forma y color:NeatPeso molecular:1197.42Ethyl 3-Oxo-4-aza-5α-androst-1-ene-17β-carboxylate
CAS:Producto controlado<p>Impurity Dutateride EP Impurity C<br>Applications Ethyl 3-Oxo-4-aza-5α-androst-1-ene-17β-carboxylate (Dutateride EP Impurity C) is a compound synthesized in the production of azasteroids. Used in the inhibition of 5α-reductase and of androgen receptor binding, both major effecters in the male hormonal system.<br>References Ramusson, G. et al.: J. Med. Chem., 29, 2298 (1986);<br></p>Fórmula:C21H31NO3Forma y color:White To Off-WhitePeso molecular:345.4817β-Estradiol-16,16,17-d3
CAS:Producto controlado<p>Applications Isotope labelled 17β-Estradiol (E888000), which is the major estrogen (1) secreted by the premenopausal ovary (2).Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA), environmental, and food contaminants.<br>References 1. Salole, E. et al.: Anal. Profiles Drug Subs. 1986 15, 23 283-3182. Lievertz, R. et al.: Am. J. Obstet. Gynecol. 1987 May;156(5):1289-93.<br></p>Fórmula:C182H3H21O2Forma y color:NeatPeso molecular:275.4017-Desethynyl Norethindrone Diacetate
CAS:Producto controlado<p>Impurity Norethindrone Acetate EP Impurity E<br>Applications 17-Desethynyl Norethindrone Diacetate (Norethindrone Acetate EP Impurity E) is an impurity of Norethindrone Acetate (N675990). Norethindrone Acetate impurity E.<br>References Pittman, C.S., et al.: Endocrinology, 68, 248 (1961),<br></p>Fórmula:C22H30O4Forma y color:NeatPeso molecular:358.4718-Methyl Nandrolone
CAS:Producto controlado<p>Applications Nandrolone (N315000(P)) derivative, which is an anabolic steroid.<br>References Poujol, N., et al.: J. Biol. Chem., 275, 24022 (2000), Roy, P., et al.: Steroid Biochem. Mol. Biol., 101, 68 (2006), Yin, D., et al.: J. Pharmacol. Exp. Ther., 304, 1323 (2003),<br></p>Fórmula:C19H28O2Forma y color:White PowderPeso molecular:288.424-[(5,6,7,8-Tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)carbonyl]benzoic Acid
CAS:Producto controlado<p>Applications 4-[(5,6,7,8-Tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)carbonyl]benzoic Acid is used in the preparation of pentamethylnaphthylmethylbenzoates as a selective retinoid X receptor ligands that induce apoptosis in leukemia cells.<br>References Boehm, M.F., et al.: J. Med. Chem., 38, 3146-55 (1995); Furmie, J.K., et al.: ChemMedChem, 7, 1551-66 (2012)<br></p>Fórmula:C23H26O3Forma y color:NeatPeso molecular:350.456a-Methyl Prednisolone 17-Propionate
CAS:Fórmula:C25H34O6Forma y color:White To Off-WhitePeso molecular:430.536β-Hydroxy Dexamethasone
CAS:<p>Applications The hydrophilic metabolite of Dexamethasone (D298800).<br>References Draper, R., et al.: Drug Res., 32, 317 (1982), Watkins, P., et al.: Clin. Pharmacol. Ther., 52, 265 (1992), Yamamoto, N., et al.: J. Clin. Oncol., 18, 2301 (2000), Slaviero, K., et al.: Br. J. Clin. Pharmacol., 57, 44 (2004),<br></p>Fórmula:C22H29FO6Forma y color:WhitePeso molecular:408.46Testosterone Laurate
CAS:Producto controladoFórmula:C31H50O3Forma y color:White To Off-WhitePeso molecular:470.732-Nitrobenzotrifluoride
CAS:Producto controlado<p>Applications 2-Nitrobenzotrifluoride can be used for self-repairing polyimide based on dynamic imine bond.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Lei, X., et.al., Faming Zhuanli Shenqing, 15, (2019);<br></p>Fórmula:C7H4F3NO2Forma y color:NeatPeso molecular:191.107Dexamethasone Phenylpropionate
CAS:Producto controladoFórmula:C31H37FO6Forma y color:NeatPeso molecular:524.624,5-Dihydro Mometasone Furoate 6-Acetate
Producto controladoFórmula:C29H34Cl2O8Forma y color:NeatPeso molecular:581.481Finasteride
CAS:Producto controladoFórmula:C23H36N2O2Forma y color:White To Off-WhitePeso molecular:372.541,2-Dihydro-deflazacort
CAS:Producto controladoFórmula:C25H33NO6Forma y color:NeatPeso molecular:443.53316-Keto 17β-Estradiol-d5 (Major)
CAS:Producto controlado<p>Applications A labelled metabolite of Estradiol (E888000).<br>References Ball, P., et al.: Steroids, 33, 563 (1979), Wong, T., et al.: Clin. Chem., 38, 1830 (1992), Xu, X., et al.: J. Clin. Endocrinol. Metab., 84, 3914 (1999), Todorovic, R., et al.: Carcinogenesis, 22, 905 (2001), Travis, R., et al.: Breast Cancer Res., 5, 239 (2003),<br></p>Fórmula:C18H17D5O3Forma y color:NeatPeso molecular:291.417-epi-Testosterone-d3
CAS:Producto controlado<p>Applications 17-epi-Testosterone-d3 is the labelled analog of 17-epi-Testosterone.Testosterone (T155000) and epitestosterone (T155005) are endogenous steroids that differ in the configuration of the hydroxyl-bearing carbon at C-17. Testosterone is the predominant male sex hormone, whereas the role of epitestosterone is largely unclear. In humans, both androgens are excreted mainly as glucuronide conjugates.<br>References Wudy, S., et al.: Steroids, 66, 759 (2001), Kootstra, P., et al.: Anal. Chim. Acta., 586, 82 (2007), Sten, T., et al.: Drug Metab. Dispos., 37, 417 (2009),<br></p>Fórmula:C192H3H25O2Forma y color:NeatPeso molecular:291.446α-Hydroxy Progesterone (>80%)
CAS:Producto controladoFórmula:C21H30O3Pureza:>80%Forma y color:NeatPeso molecular:330.46Boldione
CAS:Producto controlado<p>Impurity USP Exemestane Related Compound C<br>Applications Boldenone related steroid; anabolic androgenic steroid.<br>References Watanabe, K., et al.: J. Appl. Bacteriol., 62, 1511 (1987), Barthakur, S., et al.: J. Basic Microbiol., 36, 383 (1996),Grinenko, G., et al.: Pharmaceut. Chem. J., 36, 510 (2002), Bhat, S., et al.: J. Biol. Chem., 280, 33015 (2005),<br></p>Fórmula:C19H24O2Forma y color:NeatPeso molecular:284.395-(4-Fluorophenyl)-2,3-dihydro-3-(1-methylethyl)-2-oxo-N,4-diphenyl-1-[2-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1H-pyrrole-3-carboxamide
CAS:Producto controlado<p>Applications 5-(4-Fluorophenyl)-2,3-dihydro-3-(1-methylethyl)-2-oxo-N,4-diphenyl-1-[2-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1H-pyrrole-3-carboxamide is a photodegradation product of Atorvastatin (A791750).<br>References Cermola, F., et al.: Tetrahedron., 62, 7390 (2006);<br></p>Fórmula:C33H33FN2O5Forma y color:NeatPeso molecular:556.62Testosterone-3,4-13C2
CAS:Producto controladoFórmula:C1713C2H28O2Forma y color:NeatPeso molecular:290.41Digoxin-d3
CAS:Producto controlado<p>Applications Labelled Diogoxin (D446575). Cardiotonic. A representative lot is 95.4% d3, 3.4% d2, 1.2% d1 no dectable d0.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Aronson, J.K., et al.: Clin. Pharmacokinet, 5,137 (1980), Foss, P.R.B., Anal. Profiles Drug Subs., 9, 207 (1980),<br></p>Fórmula:C412H3H61O14Forma y color:Off White PowderPeso molecular:783.96Triamcinolone Furetonide
CAS:Producto controladoFórmula:C33H35FO8Forma y color:NeatPeso molecular:578.62Flurandrenolone Acetate
CAS:<p>Impurity Fluocinolone Acetonide EP Impurity G<br>Applications Flurandrenolone Acetate, is the derivative of Flurandrenolide (F598650), which is a Glucocorticoid, used as an antipsoriatic.<br>References Pearlman, R., et al.: Int. J. Pharm., 18, 53 (1984), Neufeld, E., et al.: J. Chromatogr., 718, 273 (1998),<br></p>Fórmula:C26H35FO7Forma y color:NeatPeso molecular:478.55
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