Esteroides y derivados
Los esteroides son compuestos orgánicos que poseen una estructura de cuatro anillos fusionados, conocida como el núcleo esteroídico. Este núcleo puede unirse a varios grupos funcionales que modifican sus propiedades y funciones biológicas. Los esteroides tienen un papel clave en la regulación de procesos metabólicos y hormonales. Se utilizan en medicina para tratar trastornos inflamatorios, autoinmunes y desequilibrios hormonales. Además, algunos derivados esteroides tienen propiedades antiinflamatorias potentes, como los corticosteroides. En terapias específicas, se usan para reducir la inflamación y controlar el dolor en diversas enfermedades.
En CymitQuimica contamos con una variedad de esteroides y sus derivados para investigación y desarrollo farmacéutico.
Se han encontrado 4964 productos de "Esteroides y derivados"
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(6a,11b,16a)-21-(Acetyloxy)-6,9-difluoro-11,16,17-trihydroxypregna-1,4-diene-3,20-dione
CAS:Producto controlado<p>Applications (6α,11β,16α)-21-(Acetyloxy)-6,9-difluoro-11,16,17-trihydroxypregna-1,4-diene-3,20-dione is an impurity of Fluocinolone Acetonide, Glucocorticoid; anti-inflammatory.<br>References Sammul, et al.: J. Assoc. Off. Agric. Chem., 47, 952 (1964), Emerson, M.V., et al.: BioDrugs, 21, 245 (2007),<br></p>Fórmula:C23H28F2O7Forma y color:NeatPeso molecular:454.46Dihydrodigoxin (Mixture of Diastereomers)
CAS:Producto controlado<p>Applications Dihydrodigoxin is a cardioinactive metabolite of Digoxin (D446575) that gets excreted in the urine after Digoxin administration in humans.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Clark, D.R., et al.: Drug Metab. Dispos., 2, 148 (1974); Reuning, R.H., et al.: Drug Metab. Dispos., 13, 51 (1985); Butler, V.P., et al.: Pharmacology, 221, 123 (1982)<br></p>Fórmula:C41H66O14Forma y color:NeatPeso molecular:782.95(25R)-26-Hydroxycholesterol
CAS:Producto controlado<p>Applications (25R)-26-Hydroxycholesterol is a desmosterol metabolite that is found in the brain. 26-Hydroxycholesterol has been used as a biomarker for carbon cycling in the northwestern Mediterranean Sea.<br>References Meljon, A., et. al.: J. Lipid Res., 53, 2469 (2012); Christodoulou, S., et. al.: Marine Chem., 113, 25 (2009)<br></p>Fórmula:C27H46O2Forma y color:NeatPeso molecular:402.6522-Hydroxymethylene Ethisterone
CAS:Producto controlado<p>Applications A derivative of Danazol (D145000).<br>References Manson, A.J., et al.: J. Med. Chem., 6, 1 (1963), Jordan, V.C., et al.: Endocrinology, 124, 1717 (1989),<br></p>Fórmula:C22H28O3Forma y color:NeatPeso molecular:340.466-Bromo-betamethasone 17,21-Dipropionate
CAS:Producto controlado<p>Stability Hygroscopic<br>Applications 6-Bromo-Betamethasone 17,21-Dipropionate (Betamethasone Dipropionate EP Impurity H) is an impurity of Betamethasone (B327000), a glucocorticoid used as an anti-inflammatory agent.<br>References Ferrante, M.G., et al.: Anal. Profiles Drug Subs., 6, 43 (1977); Li, A., et al.: Chem. Biol. Interact., 142, 7 (2002); Cruz-Monteagudo, M., et al.: Eur. J. Med. Chem., 40, 1030 (2005)<br></p>Fórmula:C28H36BrFO7Forma y color:NeatPeso molecular:583.48Fluocinolone
CAS:Producto controlado<p>Impurity Fluocinolone Acetonide EP Impurity C<br>Applications Fluocinolone, is a medication, used to treat the itching, redness, dryness, crusting, scaling, inflammation, and discomfort of various skin condition. It is also a derivative of Fluocinolone Acetonide (F455800).<br>References Sammul, et al.: J. Assoc. Off. Agric. Chem., 47, 952 (1964), Emerson, M.V., et al.: BioDrugs, 21, 245 (2007),<br></p>Fórmula:C21H26F2O6Forma y color:NeatPeso molecular:412.42Testosterone 17-Hexahydrobenzoate
CAS:Producto controlado<p>Applications Testosterone 17-Hexahydrobenzoate is a metabolite of testosterone (T155000), which is used in biological studies to determine the hemolytic and lipophilic activity of this anabolic steroid.<br>References Biagi, G.L., et al.: J. Med. Chem., 13, 944 (1970); Biagi, G. L., et al.: J. Med. Chem., 18, 873 (1975)<br></p>Fórmula:C26H38O3Forma y color:NeatPeso molecular:398.582-Hydroxy Atorvastatin Calcium Salt
CAS:Producto controlado<p>Applications di(2-Hydroxy Atorvastatin) Calcium Salt is a metabolite of Atorvastatin Calcium Salt (A791750), a selective, competitive HMG-CoA reductase inhibitor. Atorvastatin is the only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglycerides in patients with hypercholesterolemia.<br>References Kearney, A.S., et al.: Pharm. Res., 10, 1461 (1993); Heinonen, T.M., et al.: Clin. Ther., 18, 853 (1996); Whitfield, L.R., et al.: Eur. J. Drug Metab. Pharmacokinet., 25, 97 (2000)<br></p>Fórmula:C66H68CaF2N4O12Forma y color:White To YellowPeso molecular:1187.35Ursodeoxycholic acid
CAS:Pureza:98.0%Forma y color:Solid, White powderPeso molecular:392.57998657226566-Oxo D-(-)-Norgestrel
CAS:Producto controlado<p>Impurity Levonorgestrel EP Impurity J<br>Applications 6-Oxo D-(-)-Norgestrel (Levonorgestrel EP Impurity J) is an impurity of D-(-)-Norgestrel (N689510).<br></p>Fórmula:C21H26O3Forma y color:NeatPeso molecular:326.434-Fluoro-α-(2-methyl-1-oxopropyl)-γ-oxo-N,β-diphenyl-benzenebutanamide
CAS:Producto controlado<p>Impurity Atorvastatin Diketo Amide Impurity<br>Applications An Atorvastatin intermediate. Atorvastatin is a selective, competitive HMG-CoA reductase inhibitor. The only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglycerides in patients with hypercholesterolemia.<br>References Winters, R., et al.: J. Med. Chem., 36, 1735 (1993), Hagmann, W., et al.: Bioorg. Med. Chem. Lett., 10, 1975 (2000), Istvan, E., et al.: Science, 292, 1160 (2001)<br></p>Fórmula:C26H24FNO3Forma y color:White To Off-WhitePeso molecular:417.4720(R)-Hydroxy Prednisolone
CAS:Producto controlado<p>Applications Prednisolone (P703740) metabolite.<br>References Garg, V., et al.: Biopharm. Drug Disposition, 15, 163 (1994), Adham, N., et al.: Proc. Biochem., 38, 897 (2003),<br></p>Fórmula:C21H30O5Forma y color:Off-WhitePeso molecular:362.46Ciclesonide 22S-Epimer
CAS:Producto controladoFórmula:C32H44O7Forma y color:NeatPeso molecular:540.68821-Dehydro Betamethasone (mixture of the aldehyde and the hydrated form)
CAS:Producto controlado<p>Applications 21-Dehydro Betamethasone is an impurity of Betamethasone (B327000), a corticosteroid used as an anti-inflammatory agent.<br>References Chen, B., et al.: Steroids, 74, 30 (2009); Li, M., et al.: J. Pharm. Sci., 98, 894 (2009); Xiong, Y., et al.: J. Pharm. Biomed. Anal., 49, 646 (2009);<br></p>Fórmula:C22H27FO5Forma y color:NeatPeso molecular:390.453,3-Dimethoxyestra-5(10),9(11)-dien-17-one
CAS:<p>Applications 3,3-Dimethoxyestra-5(10),9(11)-dien-17-one, can be used for the synthesis of Trenbolone Acetate (T719080).<br>References Zhang, H., et al.: Fudan Xuebao, Yixueban, 29 (3), 211 (2002);<br></p>Fórmula:C20H28O3Forma y color:NeatPeso molecular:316.43Cortisol-9,12,12-d3
CAS:Producto controlado<p>Applications Isotope labelled Cortisol (H714615) a topical corticosteroid, more specifically a glucocorticoid, produced by the zona fasciculata of the adrenal gland . Cortisol is released in response to stress and a low level of blood glucocorticoids. Its primary functions are to increase blood sugar through gluconeogenesis; suppress the immune system; and aid in fat, protein and carbohydrate metabolism.<br>References Vigore, L., et al.: Cancer Biol Ther.. 15. :699 (2014); Puurunen, J. et al.: J. Clin. Endocrinol. Metab., 94, 1973 (2009);<br></p>Fórmula:C21D3H27O5Forma y color:NeatPeso molecular:365.48o-Flutamide
CAS:Producto controlado<p>Impurity Flumazenil EP Impurity F<br>Applications o-Flutamide is an isomer of Flutamide (F598850), a nonsteroidal antiandrogen drug; antineoplastic (hormonal).<br>References Neri, et al.: Endocrinology, 91, 427 (1972), Sogani, P.C., et al.: J. Urol., 122, 640 (1979), Greenway, B.A., et al.: Br. Med. J., 316, 1935 (1998),<br></p>Fórmula:C11H11F3N2O3Forma y color:NeatPeso molecular:276.21Dexamethasone-∆17,20 21-Aldehyde
CAS:<p>Applications A degradation and metabolic intermediate of Dexamethasone (D298800). A Dexamethasone enol aldehyde as inflammation inhibitor.<br>References Weiss, G., et al.: J. Clin. Endocrinol. Metab., 43, 696 (1976), Hirschmann R., et al.: Steroids, 57, 579 (1992),<br></p>Fórmula:C22H27FO4Forma y color:White To Off-WhitePeso molecular:374.4511-Deoxy Corticosterone-d7
CAS:Producto controlado<p>Applications Labelled Deoxycorticosterone. A mineralocorticoid that occurs in adrenal cortex. It acts as a precursor to Aldosterone (A514700).<br>References Bohl, C., et al.: J. Med.Chem., 47, 3765 (2004), Smith, J., et al.: Steroids, 73, 1160 (2008),<br></p>Fórmula:C21H23D7O3Forma y color:White To Off-WhitePeso molecular:337.5Betamethasone 17-Acetate
CAS:Producto controladoFórmula:C24H31FO6Forma y color:NeatPeso molecular:434.5Estrone b-D-Glucuronide Sodium Salt (>97% by HPLC)
CAS:Producto controlado<p>Applications A metabolite of 17β -Estradiol (E888000).<br>References Cekan, S., et al.: J. Steroid Biochem., 27, 95 (1989), Martin, R., et al.: Clin. Chem., 46, 100 (2000), Blackwell, L., et al.: Steroids, 68, 465 (2003)<br></p>Fórmula:C24H29O8·NaPureza:>97% by HPLCForma y color:White To Light BrownPeso molecular:468.47Betamethasone Tripropionate
CAS:<p>Impurity Betamethasone Dipropionate EP Impurity G<br>Applications Betamethasone Tripropionate (Betamethasone Dipropionate EP Impurity G) is a Betamethasone (B327000) related compound.<br>References Grootveld, M., et al.: Biochem. Pharmacol., 37, 271 (1988), Chen, B., et al.: Steriods, 74, 30 (2009), Mikami, E., et al.: J. Pharm. Biomed. Anal., 28, 261 (2002),<br></p>Fórmula:C31H41FO8Forma y color:NeatPeso molecular:560.655α-Androstanedione
CAS:Producto controlado<p>Applications 5α-Androstanedione is a metabolite of Androstendione (A637550). 5α-Androstanedione is an important intermediate in the conversion of Androstenedione to Androstanolone (A637540).<br>References Milewich, L., et al.: J. Steroid Chem., 16, 81 (1982); Stanczyk, F. Z., et al.: J. Steroid Biochem. Mol. Biol., 37, 129 (990);<br></p>Fórmula:C19H28O2Forma y color:NeatPeso molecular:288.425β-Dihydrocortisone Acetate 21-Acetate
CAS:Producto controlado<p>Applications Cortisone (C696500) derivative.<br></p>Fórmula:C23H32O6Forma y color:NeatPeso molecular:404.5(11b,16a)-9-Fluoro-11,21,21-trihydroxy-16,17-[(1-methylethylidene)bis(oxy)]pregna-1,4-diene-3,20-dione
CAS:Producto controladoFórmula:C24H31FO7Forma y color:Light YellowPeso molecular:450.50Norethindrone Acetate
CAS:<p>Applications Progesteron. Norethindrone and acetate in combination with estrogen as contraceptive (oral). It is reasonably anticipated to be a human carcinogen.<br>References Schroff, A. P., et al.: Anal. Profiles Drug Subs., 4, 268 (1975), Singh, H., et al.: Am. J. Obstet. Gynecol., 135, 409 (1979), Toews, M., et al.: Curr. Ther. Res, 41, 509 (1987),<br></p>Fórmula:C22H28O3Forma y color:White To Off-WhitePeso molecular:340.461,2-Dihydro Dexamethasone
CAS:<p>Applications A derivatives of Dexamethasone (D298800), an analog of cortical hormones.<br>References Giesen, E.M., et al.: Molec. Cell. Endocrinol., 22, 153 (1981),<br></p>Fórmula:C22H31FO5Forma y color:White To Light BeigePeso molecular:394.486β-Hydroxy-11-deoxycortisol
CAS:Producto controlado<p>Applications 6β-Hydroxy-11-deoxycortisol is a corticosteroid which is a metabolite of Cortisol (H714615), a steroid hormone, more specifically a glucocorticoid, produced by the zona fasciculata of the adrenal gland. Cortisol is released in response to stress and a low level of blood glucocorticoids.<br>References Vigore, L., et al.: Cancer Ther., 6, 699 (2008), Puurunen, J., et al.: J. Clin. Endocrinol. Metab., 94, 1973 (2009), Lemos, D., et al.: J. Endocrinol., 201, 275 (2009), Chen, S., et al.: Am. J. Physiol., 296 (2009),<br></p>Fórmula:C21H30O5Forma y color:NeatPeso molecular:362.46S-deacetyl spironolactone
CAS:<p>Applications A metabolite of Spironolactone.<br>References Morris, R., et al.: Eur. J. Clin. Pharmacol., 34, 233 (1988), Dasgupta, A., et al.: Am. J. Clin. Pathol., 111, 406 (1999)<br></p>Fórmula:C22H30O3SForma y color:NeatPeso molecular:374.54Estradiol 17-Valerate
CAS:Producto controlado<p>Applications Estradiol (E888000) derivative. An estrogen.<br>References Salole, E.G., et al.: Anal. Profiles Drug Subs., 15, 283 (1986), Lievertz, R.W., et al.: Am. J. Obstet. Gynecol., 156, 1289 (1987),<br></p>Fórmula:C23H32O3Forma y color:White To Off-WhitePeso molecular:356.509-Dehydrotestosterone
CAS:Producto controlado<p>Applications 9-Dehydrotestosterone, is the analogue of Testosterone (T155000), the principal hormone of the testes, produced by the interstitial cells. Major circulating androgen; converted by 5α-reductase in androgen-dependent target tissues to 5α-dehydrotestosterone which is required for normal male sexual differentiation. Also converted by aromatization to Estradiol.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References McFarland, K., et al.: Science, 245, 494 (1989), Heckert, L., et al.: Mol. Endocrinol., 12, 1499 (1998), Themmen, A., et al.: Endocr. Rev. 21, 551 (2000), Kumar, R., et al.: Biol. Reprod., 65, 710 (2001),<br></p>Fórmula:C19H26O2Forma y color:NeatPeso molecular:286.412-Nitrobenzotrifluoride
CAS:Producto controlado<p>Applications 2-Nitrobenzotrifluoride can be used for self-repairing polyimide based on dynamic imine bond.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Lei, X., et.al., Faming Zhuanli Shenqing, 15, (2019);<br></p>Fórmula:C7H4F3NO2Forma y color:NeatPeso molecular:191.107Hexestrol
CAS:Producto controlado<p>Applications Estrogen; antineoplastic (hormonal).<br>References Aboul-Enein, H.Y., et al.: Anal. Profiles Drug Subs., 11, 347 (1982),<br></p>Fórmula:C18H22O2Forma y color:Off-WhitePeso molecular:270.37Testosterone Undecanoate
CAS:Producto controlado<p>Applications A metabolite of Testosterone (T155000). It is a promising androgen for male hormonal contraception.CONTROLLED SUBSTANCE<br>References Glass, A., et al.: J. Clin. Endocrinol. Metab., 45, 1211 (1977), Behre, H., et al.: Eur. J. Endocrinol., 140, 414 (1999), Nieschlag, E., et al.: Steroids, 68, 965 (2003), Wang, C., et al.: J. Clin. Endocrinol. Metab., 91, 460 (2006),<br></p>Fórmula:C30H48O3Forma y color:WhitePeso molecular:456.70Anecortave
CAS:<p>Impurity Hydrocortisone Acetate EP Impurity E<br>Applications Anecortave (Hydrocortisone Acetate EP Impurity E) is an angiostatic steroid. Used in treatment of macular degeneration.<br>References Clark, A.F., et al.: Expert Opin. Invest. Drugs, 6, 1867 (1997), Slakter, J.S., et al.: Ophthalmology 110, 2372 (2003),<br></p>Fórmula:C23H30O5Forma y color:BeigePeso molecular:386.48Norgestimate
CAS:Producto controlado<p>Applications Progestogen. In combination with estrogen as oral contraceptive.<br>References Hahn, D.W., et al.: Contraception, 16, 541 (1977), Weintraub, H.S., et al.: J. Pharm. Sci., 67, 1406 (1978),<br></p>Fórmula:C23H31NO3Forma y color:White SolidPeso molecular:369.506a,9a-Difluoroprednisolone 21-Acetate
CAS:Producto controlado<p>Applications 6α,9α-Difluoroprednisolone 21-Acetate, is an impurity of Difluprednate (D445925), which is shown to have antiinflammatory activity.<br>References Toscano L., et al.: J. Med. chem., 20, 213 (1977);<br></p>Fórmula:C23H28F2O6Forma y color:White To Off-WhitePeso molecular:438.46Clobetasol Propionate Impurity E
<p>Applications Clobetasol Propionate Impurity E is an impurity of Clobetasol (C583490), which is a topical corticosteroid. Glucocorticoid; anti-inflammatory.<br>References Olsen, E.A., et al.: J. Am. Acad. Dermatol., 15, 246 (1986),<br></p>Fórmula:C25H33ClO4Forma y color:NeatPeso molecular:432.98Δ-5(10)-Norethindrone Acetate
CAS:Producto controlado<p>Impurity Norethindrone Acetate EP Impurity B<br>Applications Δ-5(10)-Norethindrone Acetate (Norethindrone Acetate EP Impurity B) is a Norethindrone Acetate (N675990) impurity. Used in studies of progesterone-binding properties of purified uteroglobin-like protein.<br>References Beato, M. et al.: J. Reprod. Fert., 53, 305 (1978); Schroff, A. P., et al.: Anal. Profiles Drug Subs., 4, 268 (1975); Singh, H., et al.: Am. J. Obstet. Gynecol., 135, 409 (1979);<br></p>Fórmula:C22H28O3Forma y color:Off-WhitePeso molecular:340.46Betamethasone 21-O-Ethyl Carbonate
CAS:Producto controlado<p>Impurity Betamethasone EP Impurity D<br>Applications Betamethasone 21-O-Ethyl Carbonate (Betamethasone EP Impurity D) is a derivative of Betamethasone (B327000); a glucocorticoid used as an anti-inflammatory agent.4<br>References Ferrante, M.G., et al.: Anal. Profiles Drug Subs., 6, 43 (1977); Li, A., et al.: Chem. Biol. Interact., 142, 7 (2002); Cruz-Monteagudo, M., et al.: Eur. J. Med. Chem., 40, 1030 (2005); Rothfuss, A., et al.: Chem. Res. Toxicol., 19, 1313 (2006); Xiong, Y., et al.: J. Pharmaceut. Biomed., 49, 646 (2009)<br></p>Fórmula:C25H33FO7Forma y color:NeatPeso molecular:464.52Estra-5(10),9(11)-diene-3,17-dione
CAS:<p>Applications Estra-5(10),9(11)-diene-3,17-dione, can be used as an intermediate for the synthesis of 3-keto-desogestrel.<br>References Wang, R., et al.: Zhongguo Yaowu Huaxue Zazhi, 4, 187 (1994);<br></p>Fórmula:C18H22O2Forma y color:NeatPeso molecular:270.366Prednival
CAS:Producto controlado<p>Applications Prednival was used in the study of inflammation-inhibiting activity of steroids.<br>References Bodor, N., et al.: J. Med. Chem., 26, 318 (1983); Stouch, T., et al.: J. Med. Chem., 29, 2125 (2986);<br></p>Fórmula:C26H36O6Forma y color:NeatPeso molecular:444.567α-Hydroxy-4-cholesten-3-one
CAS:<p>Applications 7α-Hydroxy-4-cholesten-3-one is a metabolite of Cholesterol (C432501).<br>References Connor, W., et al.: J, Clin. Invest., 48, 1363 (1969), Nestel, P., et al.: Metabolism, 24, 189 (1975), Ellegard, L., et al.: Eur. J. Clin. Nutr., 45, 451 (1991), Pedersen, A., et al.: J. Lipid Res., 41, 1901 (2000),<br></p>Fórmula:C27H44O2Forma y color:NeatPeso molecular:400.64Desmethyl Cerivastatin, Sodium Salt
CAS:Producto controladoFórmula:C25H31FNO5·NaForma y color:NeatPeso molecular:467.51Testosterone Sulfate-d3 Triethylamine Salt
CAS:Producto controlado<p>Applications The labelled analogue of a metabolite of Testosterone (T155000). It is a urinary metabolite of Androstenedione (A637550) in patients with Addison's disease and also used as a marker in blood plasma for detection of prostate cancer.<br>References Lokhov, P.G. et al.: Metabolomics, 6, 156 (2010); Bonnaire, Y. et al.: J. Anal. Toxicol., 19, 175 (1995); Tamm, J. et al.: Steroids, 8, 659 (1966);<br></p>Fórmula:C25H40D3NO5SForma y color:Off-WhitePeso molecular:472.7
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