Esteroides y derivados
Los esteroides son compuestos orgánicos que poseen una estructura de cuatro anillos fusionados, conocida como el núcleo esteroídico. Este núcleo puede unirse a varios grupos funcionales que modifican sus propiedades y funciones biológicas. Los esteroides tienen un papel clave en la regulación de procesos metabólicos y hormonales. Se utilizan en medicina para tratar trastornos inflamatorios, autoinmunes y desequilibrios hormonales. Además, algunos derivados esteroides tienen propiedades antiinflamatorias potentes, como los corticosteroides. En terapias específicas, se usan para reducir la inflamación y controlar el dolor en diversas enfermedades.
En CymitQuimica contamos con una variedad de esteroides y sus derivados para investigación y desarrollo farmacéutico.
Se han encontrado 4964 productos de "Esteroides y derivados"
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Testosterone Enanthate
CAS:Producto controlado<p>Applications Testosterone Enanthate is a derivative of testosterone (T155000), the principal hormone of the testes, produced by the interstitial cells.<br>References Janjic, M.M., et al.: Reproduct. Toxicol., 34, 686 (2012); Lacreuse, A., et al.: Physiol. Behaviour., 106, 229 (2012);<br></p>Fórmula:C26H40O3Forma y color:Colourless To Off-WhitePeso molecular:400.594’-Hydroxy Dutasteride
Producto controlado<p>Applications 4’-Hydroxy Dutasteride is an impurity of Dutasteride (D735000), a dual inhibitor of 5α-reductase isoenzymes type 1 and 2; structurally related to Finasteride (F342000). Dutasteride is used in the treatment of benign prostatic hyperplasia.<br>References Bakshi, R.K., et al.: J. Med. Chem., 38, 3189 (1995), Gisleskog, P.O., et al.: Brit. J. Clin. Pharmacol., 47, 53 (1999), Djavan, B., et al.: Expert Opin. Pharmacother., 6, 311 (2005)<br></p>Fórmula:C27H30F6N2O3Forma y color:NeatPeso molecular:544.53N-Demethyl Mifepristone
CAS:<p>Applications A metabolite of Mifepristone (M343975).<br>References Ringler, I., et al.: Metabolism, 13, 37 (1964), Gagne, D., et al.: J. Steroid. Biochem., 25, 315 (1986), Jang, G., et al.: Biochem. Pharmacol., 52, 753 (1996), Hild, S., et al.: Hum. Reprod., 15, 822 (2000), Gainer, E., et al.: Steroids, 68, 1005 (2003),<br></p>Fórmula:C28H33NO2Forma y color:NeatPeso molecular:415.57Estriol
CAS:Producto controlado<p>Applications A metabolite of Estradiol (E888000). An estrogenic metabolite considerably less potent than the hormone Estradiol (E888000).<br>References Marrian, et al.: Biochem. J., 23,1090 (1929), Huffman, et al.: J. Biol. Chem., 169, 167 (1947),<br></p>Fórmula:C18H24O3Forma y color:White To Off-WhitePeso molecular:288.3825-Hydroxy Vitamin D3 3-Sulfate Sodium Salt (90%)
CAS:Producto controlado<p>Stability Light Sensitive, Temperature Sensitive<br>Applications 25-Hydroxyvitamin D3 3-Sulfate is a metabolite of 24,25-Dihydroxyvitamin D3 and 25-Hydroxyvitamin D3 (C125700).<br>References Higashi, T. et al.: Steroids, 65, 281 (2000); Higashi, T. et al.: Ann. Clin. Biochem., 36, 43 (1999);<br></p>Fórmula:C27H43NaO5SPureza:90%Forma y color:NeatPeso molecular:502.6820,21-Dehydro Spironolactone
CAS:Producto controladoFórmula:C24H30O4SForma y color:NeatPeso molecular:414.56Androstane Spin Label (ASL)
CAS:Producto controlado<p>Applications Androstane Spin Label (ASL) is a spin labelled Androstane used to mimic Androstane.<br>References Scheidt, H., et al.: J. Biol. Chem., 278, 45563 (2003);<br></p>Fórmula:C23H38NO3Forma y color:NeatPeso molecular:376.55Trilostane
CAS:Producto controlado<p>Applications An inhibitor of steroid biosynthesis. Used as an adrenocortical suppressant. Used in the treatment of breast cancer.<br>References Komanicky, P., et al.: J. Clin. Endocrinol. Metab., 47, 1042 (1978), Mori, Y., et al., Chem. Pharm. Bull., 29, 2646 (1981), Williams, C.J., et al.: Cancer Treat. Rep., 71, 1197 (1987)<br></p>Fórmula:C20H27NO3Forma y color:WhitePeso molecular:329.43Sodium Pregnenolone-17α,21,21,21-d4 Sulfate
CAS:Producto controlado<p>Applications Sodium Pregnenolone-17alpha,21,21,21-d4 Sulfate (CAS# 1485492-21-4) is a useful isotopically labeled research compound.<br></p>Fórmula:C21H27D4NaO5SForma y color:NeatPeso molecular:422.5517β-Estradiol-d3 17-Acetate 3-β-D-Glucuronide
Producto controlado<p>Applications A labelled Estradiol (E888000) derivative.<br></p>Fórmula:C26H31D3O9Forma y color:NeatPeso molecular:493.56(20S)-Dexamethasone Epimeric Glycolic Acid
CAS:Fórmula:C22H29FO6Forma y color:NeatPeso molecular:408.46(3β)-Cholesta-4,6-dien-3-ol
CAS:<p>Applications (3β)-Cholesta-4,6-dien-3-ol is a Cholesterol (C432501) and Cholestane (C431700) derivative which has the potential to act as an antiinflammatory and antifungal compound.<br>References Felicio, R. et al.: J. Pharm. Biomed. Anal., 52, 763 (2010); Rosin, Z., et al.: Physiol. Chem., 124, 282 (1923), Schoenheimer, et al.: J. Biol. Chem., 105, 355 (1934), Gemant, et al.: Life Sci., 1, 233 (1962), Johnson, K., et al.: 4, 457 (1964),<br></p>Fórmula:C27H44OForma y color:NeatPeso molecular:384.64δ7,9(11)-Dexamethasone
CAS:<p>Stability Hygroscopic<br>Applications Dexamethasone (D298800) process impurity.<br></p>Fórmula:C22H26O4Forma y color:NeatPeso molecular:354.443(R,S)-Hydroxy Desogestrel
CAS:Producto controlado<p>Applications A metabolite of Desogestrel.<br>References Back, D., et al.: Br. J. Clin. Pharmacol., 26, 23 (1988), Wienkers, L., et al.: Drug Metab. Dispos., 1990, 24, 610 (1990), Bourrie, M., et al.: J. Pharmacol. Exp. Ther., 277, 321 (1996), Ono, S., et al.: Xenobiotica, 26, 681 (1996),<br></p>Fórmula:C22H30O2Forma y color:NeatPeso molecular:326.473-Keto Fluvastatin Sodium Salt
CAS:Producto controlado<p>Stability Light Sensitive<br>Applications An impurity of Fluvastatin.<br></p>Fórmula:C24H23FNO4·NaForma y color:NeatPeso molecular:431.43Betamethasone-∆17,20 21-Aldehyde(Mixture of Isomers)
CAS:Producto controlado<p>Applications A degradation and metabolic intermediate of Betamethasone (B3270000).<br></p>Fórmula:C22H27FO4Forma y color:NeatPeso molecular:374.45Fulvestrant
CAS:Producto controladoFórmula:C32H47F5O3SForma y color:White To Off-WhitePeso molecular:606.77Triamcinolone 21-Acetate
CAS:Producto controlado<p>Impurity Triamcinolone EP Impurity B<br>Applications Triamcinolone 21-Acetate is an impurity of Triamcinolone (T767160), a glucocorticoid used as an antiasthmatic.<br>References Florey, K., et al.: Anal. Profiles Drug Subs., 1, 397 (1972), Bernstein, I.L., et al.: Chest, 81, 20 (1982)<br></p>Fórmula:C23H29FO7Forma y color:White To Off-WhitePeso molecular:436.476β-Muethyl Prednisolone 21-Acetate (>90%)
CAS:Producto controlado<p>Applications 6β-Μethyl Prednisolone 21-Acetate is the 6-methyl isomer of 6α-Methyl Prednisolone 21-Acetate (M326030).<br>References Sugihara, N., et al: Am. J. Cardiol., 69, 1475 (1992), Bracken, M.B., et al.: J. Neurosurg., 89, 699 (1998), Dammers, J.W.H.H., et al.: Brit. Med. J., 319, 884 (1999).<br></p>Fórmula:C24H32O6Pureza:>90%Forma y color:NeatPeso molecular:416.515,6-Dehydro-17b-dutasteride
CAS:Producto controlado<p>Impurity Dutateride EP Impurity G<br>Applications 5,6-Dehydro-dutasteride (Dutateride EP Impurity G) is an impurity in the synthesis of Dutasteride (D735000), a dual inhibitor of 5α-reductase isoenzymes type 1 and 2; structurally related to Finasteride (F342000). Dutasteride is used in the treatment of benign prostatic hyperplasia.<br>References Bakshi, R.K., et al.: J. Med. Chem., 38, 3189 (1995), Gisleskog, P.O., et al.: Brit. J. Clin. Pharmacol., 47, 53 (1999), Djavan, B., et al.: Expert Opin. Pharmacother., 6, 311 (2005),<br></p>Fórmula:C27H28F6N2O2Forma y color:NeatPeso molecular:526.51Testosterone-d3 β-D-Glucuronide Monosodium Salt
CAS:Producto controlado<p>Applications Labelled Metabolite of Testosterone (T155000).<br>References Shibata, N., et al.: Biochem. J., 368, 783 (2002), Sonneveld, E., et al.: Toxicol. Sci., 83, 136 (2005), Schulze, J., et al.: J. Clin. Endocrinol. Metab., 93, 2500 (2008), Sten, T., et al.: Drug<br></p>Fórmula:C25H32D3NaO8Forma y color:Off-WhitePeso molecular:489.5521-Dehydrocorticosterone (mixture of the aldehyde and the hydrated form)
CAS:Fórmula:C21H28O4Forma y color:NeatPeso molecular:344.44Protodioscin
CAS:<p>Applications Protodioscin is a steroidal saponin compound found in a number of plant species. It is known to be the active component of the herbal aphrodisiac plant Tribulus terrestris. It has also shown to produce significant increases in the levels of the hormonal levels in animal studies.<br>References Gauthaman, K., et al.: Inter. J. Phytother. Phytopharm., 15, 44 (2008); Ganzera, M., et al.: J. Pharmac. Sci., 90(11), 1752 (2001);<br></p>Fórmula:C51H84O22Forma y color:Off-White To Light BeigePeso molecular:1049.2017α-Hydroxy Pregnenolone-d3
CAS:Producto controlado<p>Applications A labelled metabolite of Pregnenolone (P712200).<br>References Kramer, R., et al.: J. Steroid Biochemi., 18, 715 (1983), Hiwatashi, A., et al.: J. Biochem., 98, 619 (1985), Eiichi, T., et al.: J. Pharmacol. Sci., 95, 140 (2004),<br></p>Fórmula:C212H3H29O3Forma y color:NeatPeso molecular:335.50Andarine
CAS:Producto controlado<p>Applications It is a potent and tissue-selective androgen receptor modulator (SARM) used as antiosteoporotic agent.<br>References Samnegard, E., et al.: Bone, 28, 414 (2001), Hanada, K., et al.: Biol. Pharm. Bull., 26, 1563 (2003), Kearbey, J., et al.: Xenobiotica, 34, 273 (2004), Kearbey, J., et al.: Xenobiotica, 34, 273 (2004), Kearbey, J., et al.: Pharm. Res., 24, 328 (2007),<br></p>Fórmula:C19H18F3N3O6Forma y color:Light YellowPeso molecular:441.364-Hydroxy Estradiol 1-N7-Guanine
CAS:Producto controlado<p>Applications 4-Hydroxy Estradiol 1-N7-Guanine is an estrogen metabolite formed with DNA which can lead to the mutations that initiate breast, prostate, and other types of cancer. Estrogen-DNA depurinating adducts as biomarkers of cancer risk and their use in cancer detection and prevention.<br>References Chakravarti, D., et al.: Mutat. Res., 456, 17 (2000), Liehr, J., et al.: Endocr. Rev., 21, 4054 (2000), Chakravarti, D., et al.: Oncogene, 20, 7945 (2001), Cavalieri, E., et al.: Chem. Res. Toxicol., 14, 1041 (2002),<br></p>Fórmula:C23H27N5O4Forma y color:NeatPeso molecular:437.4916α-Methyl-11-oxo Prednisolone
CAS:Producto controlado<p>Applications A 16α-substituted Prednisolone as potent topical antiinflammatory agent.<br>References Lutsky, B.N., et al.: Arzneim.-Forsch., 29, 1662 (1979),<br></p>Fórmula:C22H28O5Forma y color:White SolidPeso molecular:372.451,2-Dihydro Desoxymetasone
CAS:Producto controlado<p>Applications A metabolite of Desoxymetasone (D296970).<br>References Schriks, M., et al.: Environ. Sci. Technol., 44, 4766 (2010), Baeck, M., et al.: Eur. J. Dermatol., 20, 102 (2010), Lee, P., et al.: Bioorg. Med. Chem. Lett., 20, 69 (2010),<br></p>Fórmula:C22H31FO4Forma y color:NeatPeso molecular:378.484-Methoxy Estrone
CAS:Producto controlado<p>Applications An endogenous estrogen metabolite, risk-factor for development of breast cancer.<br>References Beral, V., et al.: Lancet, 362, 419 (2003), Nelson, R., et al.: Clin. Chem., 50, 373 (2004), Malekinejad, H., et al.: J. Agric. Food Chem., 54, 9785 (2006),<br></p>Fórmula:C19H24O3Forma y color:Off White SolidPeso molecular:300.396α-Hydroxy 17β-Estradiol
CAS:Producto controladoFórmula:C18H24O3Forma y color:NeatPeso molecular:288.384-Hydroxy Ospemifene (Ospemifene Impurity)
CAS:<p>Applications 4-Hydroxy Ospemifene is an Ospemifene (O703000) impurity, used to treat dyspareunia. It is a selective estrogen receptor modulator (SERM) acting similarly to an estrogen.<br>References Rutanen, E., et al.: Menopause, 10, 433 (2003);<br></p>Fórmula:C24H23ClO3Forma y color:NeatPeso molecular:394.89Estrone 3-Sulfate Sodium Salt, Stabilized with TRIS
CAS:Fórmula:C18H21O5S·NaForma y color:NeatPeso molecular:372.412-Methyl-N-[3-(trifluoromethyl)phenyl]propanamide
CAS:Producto controladoFórmula:C11H12F3NOForma y color:NeatPeso molecular:231.21Pregna-4,14-diene-3,20-dione
CAS:Producto controlado<p>Impurity Progesterone EP Impurity A<br>Applications Pregna-4,14-diene-3,20-dione (Progesterone EP Impurity A) is a Progesterone derivative<br>References Wilks, J., et al.: Steroids, 35, 697 (1980), Templeton, J., et al.: J. Med. Chem., 30, 1502 (1987), Blackmore, P., et al.: Mol. Pharmacol., 49, 727 (1996),<br></p>Fórmula:C21H28O2Forma y color:NeatPeso molecular:312.45Estrone Enol Diacetate
CAS:Producto controlado<p>Applications Estrone Enol Diacetate can be applied as a substrate for human paroxonases. A steroid with potential to be inhibitor of NADH-oxidase and succinate oxidase.<br>References Teiber, J. et al.: Arch. Biochem. Bioiphys. 461, 24 (2007); Stoppani, A. et al.: Arch. Biochem. Biophys., 127, 463 (1968)<br></p>Fórmula:C22H26O4Forma y color:Off-WhitePeso molecular:354.4416-Epiestriol
CAS:Producto controlado<p>Impurity Estriol EP Impurity F<br>Applications 16-Epiestriol (Estriol EP Impurity F) is a metabolite of Estradiol.<br>References Marrian, B., et al.: Biochem. J., 59, 136 (1955), Dietel, M., et al.: Cancer Res., 50, 6100 (1990), Schumacher, G., et al.: Clin. Cancer Res., 5, 493 (1999), Robert, J., et al.: J. Med. Chem., 46, 4805 (2003),<br></p>Fórmula:C18H24O3Forma y color:WhitePeso molecular:288.386(7)-Dehydro Norgestrel
CAS:<p>Impurity Levonorgestrel EP Impurity M<br>Applications 6(7)-Dehydro Norgestrel (Levonorgestrel EP Impurity M) is a Norgestrel (N689500) impurity.<br>References Gorog, S., et al.: J. Chromatogr., 400 177 (1987),<br></p>Fórmula:C21H26O2Forma y color:NeatPeso molecular:310.43(Z)-Guggulsterone
CAS:Producto controlado<p>Applications (Z)-Guggulsterone acts as an α-glucosidase inhibitor also known as a hypolipidemic agent.<br>References Yang, D. et al.: J. Lipid Res., 53, 529 (2012); El-Mekkawy, S. et al.: Nat. Prod. Res., 27, 146 (2013);<br></p>Fórmula:C21H28O2Forma y color:NeatPeso molecular:312.45(16β)-17,21-Dihydroxy-16β-methyl-pregna-1,4,9(11)-triene-3,20-dione
CAS:Producto controlado<p>Impurity Betamethasone EP Impurity C<br>Applications (16β)-17,21-Dihydroxy-16β-methyl-pregna-1,4,9(11)-triene-3,20-dione (Betamethasone EP Impurity C) is used in biological studies to perform preclinical characterization of VBP15, a novel anti-inflammatory delta 9,11 steroid. This compound is also used in analytical studies to determine the stability from reversed-phase high performance liquid chromatography (RP-HPLC) to separate low levels of dexamethasone and other related compounds from betametasone, which is an active pharmaceutical ingredient.<br>References Reeves, E.K.M., et al.: Bioorg., Med. Chem., 21, 2241 (2013), Xiong, Y., et al.: J. Pharm. Biomed. Anal., 49, 646 (2009)<br></p>Fórmula:C22H28O4Forma y color:NeatPeso molecular:356.46Digitoxin
CAS:<p>Stability Hygroscopic<br>Applications Cardiotonic.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Foerster, et al.: Arch. Int. Pharmacodyn. Ther., 159, 1 (1966), Jakovljevic, I.M., Anal. Profiles Drug Subs., 3, 149 (1974)<br></p>Fórmula:C41H64O13Forma y color:White To Off-WhitePeso molecular:764.94(11α,16α)-9,11-Epoxy-17,21-dihydroxy-16-methylpregna-1,4-diene-3,20-dione
CAS:<p>Applications (11α,16α)-9,11-Epoxy-17,21-dihydroxy-16-methylpregna-1,4-diene-3,20-dione, can be used for the synthesis of Calicoferol E, a vitamin D3 analogues.<br>References Vir Singh, T., et al.: ARKAT USA, INc., (2002);<br></p>Fórmula:C22H28O5Forma y color:White To Light RedPeso molecular:372.45Exemestane-19-d3
CAS:Producto controlado<p>Stability Light Sensitive<br>Applications An antineoplastic (hormonal).<br>References Giudici, D., et al.: J. Steroid Biochem., 30, 391 (1988), Evans, T.R.J., et al.: Cancer Res., 52, 5933 (1992), Zilembo, N., et al.: Brit. J. Cancer, 72, 1007 (1995)<br></p>Fórmula:C20H21D3O2Forma y color:NeatPeso molecular:299.42Betamethasone 17-Propionate
CAS:Producto controlado<p>Impurity Clobetasol Propionate EP Impurity A / Betamethasone Dipropionate EP Impurity B<br>Applications Betamethasone 17-Propionate (Clobetasol Propionate EP Impurity A) is a degradation product of Betamethasone. Glucocorticoid.<br>References Andersson, P., et al.: J. Pharm. Pharmacol., 36, 763 (1984), Wurthwein, G., et al.: Biopharm. Drug Dispos., 11, 381 (1990), Samtani, M., et al.: J. Pharm. Sci., 93, 726 (2004), Samtani, M., et al.: Drug Metab. Dispos., 33, 1124 (2005),<br></p>Fórmula:C25H33FO6Forma y color:Off-WhitePeso molecular:448.52Tachysterol3 (80%)
CAS:Producto controlado<p>Impurity Cholecalciferol EP Impurity E<br>Stability Light Sensitive, Temperature Sensitive, Unstable in DMSO<br>Applications Tachysterol3 (Cholecalciferol EP Impurity E) is a bioactive, synthetic vitamin D3 analog.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Bouillon, R., et al.: Endocr. Rev., 16, 200 (1995), Ettinger, R., et al.: Adv. Drug Res., 28, 269 (1996), Doi, T., et al.: Tetrahedr. Lett., 45, 5727 (2004),<br></p>Fórmula:C27H44OPureza:80%Forma y color:Colourless To YellowPeso molecular:384.6411a-Hydroxy Canrenone
CAS:Producto controlado<p>Applications 11α-Hydroxy Canrenone is the key intermediate in the synthesis of Eplerenone, a cardiovascular drug. Canrenone was biotransformed into 11α-Hydroxycanrenone by Aspergillus ochraceus SIT34205.<br>References Luetscher, J., et al.: J. Clin. Invest., 29, 1576 (1950), Gaunt, R., et al.: J. Clin. Endocrinol. Metab., 15, 621 (1955), McMahon, E., et al.: Curr. Opin. Pharm., 1, 190 (2001), McMahon, E., et al.: Curr. Pharm. Des., 9, 1065 (2003),<br></p>Fórmula:C22H28O4Forma y color:NeatPeso molecular:356.46Aldosterone
CAS:<p>Applications Aldosterone is an adrenocortical steroid which exerts regulatory influence on metabolism of electrolytes and water. Biologically active aldosterone isomer; a mineralocorticoid produced by the adrenal cortex that induces urinary excretion of K+ and renal reabsorptioon of Na+. Exists as an equilibrium mixture of the aldehyde and the hemiacetal.<br>References Simpson, et al.: Experienta, 9, 333 (1953), Morel, A., et al.: Nature, 356, 523 (1992), Arima, S., et al.: Clin. Exp. Nephrol., 7, 172 (2003), Hirasawa, A., et al.: Eur. J. Pharmacol., 267, 71 (1994), Hiroyama, M., et al.: Mol. Endocrinol., 21, 247 (2007),<br></p>Fórmula:C21H28O5Forma y color:White To Off-WhitePeso molecular:360.44BGP 15
CAS:Producto controlado<p>Applications BGP 15 is a calcipotriene-based vitamin D3 analog that inhibits poly(ADP-ribose) polymerasesis (PARP), a class of enzymes that regulate DNA repair and apoptosis (1). BGP 15 is also a cardioprotective agent (2). Also, BPG 15 improves mitochondrial function, protects neurons from dying in vitro and in vivo, and promotes cardiac innervation in vivo.<br>References (1) Berkovich, L., et al.: Anticancer Drugs. 21, 609 (2010) (2) Szabados, E., et al. Biochem Pharmacol. 59, 937 (2000)<br></p>Fórmula:C14H22N4O2·2HClForma y color:NeatPeso molecular:351.2717β-Estradiol-d3 3-β-D-Glucuronide
CAS:Producto controlado<p>Stability Hygroscopic<br>Applications A labelled metabolite of Estradiol (E888000).<br>References Agasan, A., et al.: J. Immunol. Methods., 177, 251 (1994), Stone, R., et al.: Science, 265, 308 (1994), Tacey, R., et al.: J. Pharm. Biomed. Anal., 2, 1303 (1994),<br></p>Fórmula:C24H29D3O8Forma y color:NeatPeso molecular:451.52
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