Esteroides y derivados
Los esteroides son compuestos orgánicos que poseen una estructura de cuatro anillos fusionados, conocida como el núcleo esteroídico. Este núcleo puede unirse a varios grupos funcionales que modifican sus propiedades y funciones biológicas. Los esteroides tienen un papel clave en la regulación de procesos metabólicos y hormonales. Se utilizan en medicina para tratar trastornos inflamatorios, autoinmunes y desequilibrios hormonales. Además, algunos derivados esteroides tienen propiedades antiinflamatorias potentes, como los corticosteroides. En terapias específicas, se usan para reducir la inflamación y controlar el dolor en diversas enfermedades.
En CymitQuimica contamos con una variedad de esteroides y sus derivados para investigación y desarrollo farmacéutico.
Se han encontrado 4964 productos de "Esteroides y derivados"
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(17β)-N-(1,1-Dimethylethyl)-3-oxoandrost-4-ene-17-carboxamide
CAS:Producto controladoFórmula:C24H37NO2Forma y color:Off-WhitePeso molecular:371.56Prednisolone Tebutate
CAS:Producto controlado<p>Applications Prednisolone Tebutate is an anaesthetic corticosteroid.<br>References Lewis, A. et al.: Agents and Actions, 10, 258 (1980); Myers, S. et al.: Arthris. Rheum., 28, 1275 (1985);<br></p>Fórmula:C27H38O6Forma y color:NeatPeso molecular:458.59Bisnorcholenaldehyde
CAS:Producto controlado<p>Applications Bisnorcholenaldehyde can be used to prepare 27-Nor-Δ4-dafachronic acid as a synthetic ligand of Caenorhabditis elegans DAF-12 receptor. It is also used to synthesize 3β,6α-dihydroxy-5α-cholan-23-one.<br>References Samaja, G., et al.: Bioorg. Med. Chem. Lett., 23, 2893 (2013); Nahar, L., et al.: Tetrahedron, 59, 8623 (2003)<br></p>Fórmula:C22H32O2Forma y color:NeatPeso molecular:328.4917α-Estradiol-16,16,17-d3
CAS:Producto controlado<p>Applications Labelled Estradiol. Estradiol (known as α-Estradiol or 17 α-Estradiol) is a biologically active estrogen in human breast cancer cells in tissue culture. 17-Εstradiol and its selective receptor, ER-X, are not part of a classical hormone/receptor endocrine system but of a system with important autocrine/paracrine functions in the developing and adult brain. 17-Estradiol may have enormous implications for hormone replacement strategies at the menopause and in the treatment of such neurodegenerative disorders as Alzheimer’s disease and ischemic stroke.<br>References Salole, E.G., Anal. Profiles Drug Subs., 15, 283 (1986), Lievertz, R.W., et al.: Am. J. Obstret. Gynecol., 156, 1289 (1987), Kuhnz, W., et al.: Arzneim.-Forsch., 43, 966 (1993),<br></p>Fórmula:C18H21D3O2Forma y color:NeatPeso molecular:275.4Gestodene
CAS:Producto controlado<p>Applications Gestodene is an orally active gestogen with a progesterone-like profile of activity. Gestodene is used in combination with estrogen as an oral contraceptive.<br>References Duesterberg, B., et al.: Contraception, 24, 673 (1981), Duesterberg, B., et al.: Seroids, 43, 43 (1984), Losert, W., et al.: Arzneim.-Forsch., 35, 459 (1985),<br></p>Fórmula:C21H26O2Forma y color:NeatPeso molecular:310.43Lathosterol
CAS:<p>Applications A Cholesterol (C432501) metabolite. Lathosterol (indicating cholesterol synthesis) and Sitosterol (indicating cholesterol absorption) also decreased with deteriorating health. Low Lathosterol, Sitosterol (S497050), and Cholesterol (C432501) predicted mortality additively and independently of each other.<br>References Chyou, P., et al.: Age Ageing, 29, 69 (2000), Schatz, I., et al.: Lancet, 358, 351 (2001), Bjorkman, M., et al.: Eur. J. Endocrinol., 158, 749 (2008),<br></p>Fórmula:C27H46OForma y color:White To Off-WhitePeso molecular:386.65Ruscogenin
CAS:<p>Applications A major steroidal sapogenin from Radix ophiopogon japonicus with robust anti-inflammatory and anti-thrombotic activities. Studies suggest that it inhibits adhesion of leukocytes to a human umbilical vein endothelial cell line (ECV304) injured by tumor necrosis factor-α (TNF-α) in a concentration-dependent manner.<br>References Huang, Y. et al.: Drug Dev. Res., 69, 196 (2008); Huang, Y. et al.: J. Pharmacol. Sci., 108, 198 (2008); Song, J. et al.: J. Pharmacol. Sci., 113, 409 (2010);<br></p>Fórmula:C27H42O4Forma y color:NeatPeso molecular:430.622,3-Dichloro-5,6-dicyanobenzoquinone
CAS:<p>Applications An oxidizing agent, especially in steroid synthesis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>Fórmula:C8Cl2N2O2Forma y color:NeatPeso molecular:227.0Tetrahydrodehydrocorticosterone
CAS:Producto controlado<p>Applications Tetrahydrodehydrocorticosterone inhibits aldosteronogenesis by intact cells at concentrations that inhibited angiotensin binding.<br>References Campanile, C.P., Goodfriend, T.L.: Steroids, 37, 681(1981)<br></p>Fórmula:C21H32O4Forma y color:NeatPeso molecular:348.48Estriol lactone impurity
CAS:Producto controladoFórmula:C18H22O3Forma y color:NeatPeso molecular:286.37Gestrinone
CAS:Producto controlado<p>Applications Gestrinone is a Steroidal antiestrogen, antiprogestogen, analog of Norgestrienone. Antigonadotropin.Controlled substance.<br>References Azadian-Boulanger, G., et al.: Am. J. Obstet. Gynecol., 125, 1049 (1976), Thomas, E.J., et al.: Br. Med. J., 294, 272 (1987), Coutinho, E.M., et al.: Fertil. Steril., 49, 418 (1988),<br></p>Fórmula:C21H24O2Forma y color:NeatPeso molecular:308.40Fluvastatin
CAS:<p>Fluvastatin (XU-62320) is an HMG-CoA reductase inhibitor used to lower plasma cholesterol levels and prevent cardiovascular disease.</p>Fórmula:C24H26FNO4Pureza:98.94%Forma y color:SolidPeso molecular:411.47Ref: 10-F979169
5mgA consultar10mgA consultar25mgA consultar50mgA consultar100mgA consultar250mgA consultarGlycine, N-[(3α,5β,7α,12α)-3,7,12-trihydroxy-24-oxocholan-24-yl]-, monosodium salt, monohydrate
CAS:Pureza:97%Peso molecular:505.628δ1-Adrenosterone
CAS:Producto controlado<p>Applications Δ1-Adrenosterone is a derivative of Adrenosterone (A305600), and is suspected to have some inhibitory effects on estrogen biosynthesis in human placental microsomes. Δ1-Adrenosterone also has potential androgenic anabolic and antiuterotropic activity.<br>References Lodge, B., et al.: Can. J. Pharm. Sci., 10, 107 (1975); Lodge, B., et al.: Can. J. Pharm. Sci., 11, 95 (1976); Schwarzel, W., et al.: Endocrinology, 92, 866 (1973)<br></p>Fórmula:C19H22O3Forma y color:NeatPeso molecular:298.38Ref: 10-F794924
5gA consultar10gA consultar25gA consultar100gA consultar250gA consultar500gA consultar100mgA consultarAlgestone
CAS:Producto controlado<p>Applications A pregnane steroid, its acetonide is used as anti-inflammatory drug (topical) and combination with enanthate as injectable contraceptive.<br>References Hydorn, A., et al.: Steroids, 3, 493 (1964), Plesner, R., et al.: Acta Endorcinol., 61, 494 (1969),<br></p>Fórmula:C21H30O4Forma y color:NeatPeso molecular:346.4617a-Dihydro Equilenin
CAS:Producto controlado<p>Applications The 17α-metabolite of Equilin (E592800).<br>References Enmark, E., et al.: J. Clin. Endocrinol. Metab., 82, 4258 (1997), Wang, Z., et al.: J. Med. Chem., 43, 2419 (2000), Jiang, X., et al.: Steroids, 71, 334 (2006),<br></p>Fórmula:C18H20O2Forma y color:NeatPeso molecular:268.35O,O-Dimethyl Methylphosphonate
CAS:Producto controlado<p>Applications O,O-Dimethyl Methylphosphonate is a commercially used preignition additive for gasoline, anti-foaming agent, plasticizer, stabilizer and antistatic agents.<br>References Jang, S.H., et al.: J. Korean. Phy. Soc., 55, 294 (2009); Schneider, B.B., et al.: Int. J. Mass. Spectro., 298, 45 (2010);<br></p>Fórmula:C3H9O3PForma y color:NeatPeso molecular:124.076Desmosterol
CAS:<p>Applications A metabolite of Cholesterol (C432501).<br>References Marx, J., et al.: Science, 294, 508 (2001), Plosch, T., et al.: J. Biol. Chem., 277, 33870 (2002), Lund, E., et al.: J .Biol. Chem., 278, 22980 (2003),<br></p>Fórmula:C27H44OForma y color:White To Off-WhitePeso molecular:384.64Z,Z-Dienestrol-D6
CAS:Producto controlado<p>Applications A labelled metabolite of Diethylstilbestrol.<br>References Liehr, J.G., et al.: Steroids, 40, 713 (1982),<br></p>Fórmula:C18H12D6O2Forma y color:NeatPeso molecular:272.3711-Deoxy Corticosterone
CAS:Producto controlado<p>Applications A mineralocorticoid that occurs in adrenal cortex. It acts as a precursor to Aldosterone (A514700).<br>References Bohl, C., et al.: J. Med.Chem., 47, 3765 (2004), Smith, J., et al.: Steroids, 73, 1160 (2008),<br></p>Fórmula:C21H30O3Forma y color:White To Light YellowPeso molecular:330.466-Keto Fulvestrant
<p>Applications Fulvestrant (F862500) impurity F.<br></p>Fórmula:C32H45F5O4SForma y color:NeatPeso molecular:620.75(3a)-Allopregnanolone Sulfate Pyridinium Salt
CAS:Producto controlado<p>Applications (3α)-Allopregnanolone Sulfate is the sulfate conjugate of (3α)-Allopregnanolone (A547100), a metabolite of progesterone and potent positive modulator of GABAA receptors.<br>References El-Etr, M. et al.: Brain Res., 790, 334 (1998); Hauser, C.A.E. et al.: Eur. J. Pharmacol. Mol. Pharmacol. Sec., 289, 249 (1995);<br></p>Fórmula:C26H39NO5SForma y color:White To Off-WhitePeso molecular:477.667-Ketoabiraterone Acetate
CAS:Producto controlado<p>Applications 7-Ketoabiraterone Acetate is an impurity of Abiraterone (A108490), a steroidal cytochrome P 450 17α-hydroxylase-17,20-lyase inhibitor (CYP17), is currently undergoing phase II clinical trials as a potential drug for the treatment of androgen-dependent prostate cancer.<br>References Denis, L., et al.: Cancer, 72, 3888 (1993); Potter, G.A., et al.: J. Med. Chem., 38, 2463 (1995); Denmeade, S., et al.: Nat. Rev., 2, 389(2002); Scher, H., et al.: J. Clin. Oncol., 23, 8253 (2005)<br></p>Fórmula:C26H31NO3Forma y color:NeatPeso molecular:405.53Testosterone-16,16,17-d3
CAS:Producto controlado<p>Applications Labelled Testosterone (T155000). Principal hormone of the testes, produced by the interstitial cells. Major circulating androgen; converted by 5α-reductase in androgen-dependent target tissues to 5α-dehydrotestosterone which is required for normal male sexual differentiation. Also converted by aromatization to Estradiol.Controlled substance (anabolic steroid). Androgen.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References McFarland, K., et al.: Science, 245, 494 (1989), Heckert, L., et al.: Mol. Endocrinol., 12, 1499 (1998), Themmen, A., et al.: Endocr. Rev. 21, 551 (2000), Kumar, R., et al.: Biol. Reprod., 65, 710 (2001),<br></p>Fórmula:C192H3H25O2Forma y color:NeatPeso molecular:291.446b-Hydroxy Norethindrone
CAS:Producto controlado<p>Impurity Norethindrone EP Impurity H<br>Applications 6β-Hydroxynorethindrone (Norethindrone EP Impurity H) is the 6β-hydroxy analogue of Norethindrone (N676000). 6β-Hydroxynorethindrone is also a metabolite of the progestagen hormone, Lynestrenol.<br>References Choudhary, M.I. et al.: Nat. Prod. Res., 24, 1 (2010); Bagocsi, B. et al.: J. Plan. Chrom. Mod. TLC, 16, 359 (2003);<br></p>Fórmula:C20H26O3Forma y color:NeatPeso molecular:314.42Clobetasol 17-Propionate
CAS:Producto controlado<p>Applications Topical corticosteroid. Glucocorticoid; anti-inflammatory.<br>References Olsen, E.A., et al.: J. Am. Acad. Dermatol., 15, 246 (1986),<br></p>Fórmula:C25H32ClFO5Forma y color:White To Off-WhitePeso molecular:466.97Tachysterol (>90%)
CAS:<p>Stability Light Sensitive, Temperature Sensitive<br>Applications Bioactive, synthetic vitamin D3 analog; exhibits antiproliferative effect on keratinocytes. Antipsoriatic.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Matsunaga, T., et al.: J. Dermatol., 17, 135 (1990), Gerritsen, M.J.P., et al.: Br. J. Dermatol., 131, 57 (1994),<br></p>Fórmula:C28H44OPureza:>90%Forma y color:NeatPeso molecular:396.65Estrone sulfate sodium
CAS:<p>Estrone sulfate sodium, an inactive estrogen ester, transforms into estrone via steroid sulfatase. It's studied for targeting polypeptide transporters.</p>Fórmula:C18H21NaO5SPureza:98% - 99.83%Forma y color:SolidPeso molecular:372.416α-Methyl Hydrocortisone
CAS:<p>Applications A metabolite of Cortisone (C696500).<br>References Mashkovskii, M., et al.: Med. Agents, 2, 34 (2002),<br></p>Fórmula:C22H32O5Forma y color:Off-White To BeigePeso molecular:376.496-Ethylchenodeoxycholic-d5 Acid
CAS:Producto controlado<p>Applications 6-Ethylchenodeoxycholic-d5 Acid is an isotope labelled compound of 6-Ethylchenodeoxycholic Acid (E899810), which is used in the investigative treatment of primary biliary cholangitis. Primary biliary cholangitis is an autoimmune disease of the liver that slowly progresses to cirrhosis.<br>References Ali, A. H, et al.: Expert Opin. Orphan Drugs, 4, 1011 (2016)<br></p>Fórmula:C26H39D5O4Forma y color:NeatPeso molecular:425.666b-Bromo Androstenedione
CAS:Producto controlado<p>Applications Androstenedione (A637550) analog, an aromatase inhibitor.<br>References Marsh, D.A., et al.: J. Med. Chem., 28, 788 (1985),<br></p>Fórmula:C19H25BrO2Forma y color:NeatPeso molecular:365.30Dihydrodigoxin (Mixture of Diastereomers)
CAS:Producto controlado<p>Applications Dihydrodigoxin is a cardioinactive metabolite of Digoxin (D446575) that gets excreted in the urine after Digoxin administration in humans.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Clark, D.R., et al.: Drug Metab. Dispos., 2, 148 (1974); Reuning, R.H., et al.: Drug Metab. Dispos., 13, 51 (1985); Butler, V.P., et al.: Pharmacology, 221, 123 (1982)<br></p>Fórmula:C41H66O14Forma y color:NeatPeso molecular:782.9516a-Hydroxy Progesterone
CAS:Producto controlado<p>Stability Hygroscopic<br>Applications 16α-Hydroxyprrogesterone is a hydroxylated metabolite of Progesterone (P755900). 16α-Hydroxyprogesterone binds to human progesterone receptors hPR-A and hPR-B and act as an agonist for both receptors.<br>References Ikonen, M. et al.: Nature, 212, 716 (1966); Storbeck, K.-H. et al.: Mol. Cell. Endocrinol., 336, 92 (2011);<br></p>Fórmula:C21H30O3Forma y color:Off-WhitePeso molecular:330.462-Hydroxymethylene Ethisterone
CAS:Producto controlado<p>Applications A derivative of Danazol (D145000).<br>References Manson, A.J., et al.: J. Med. Chem., 6, 1 (1963), Jordan, V.C., et al.: Endocrinology, 124, 1717 (1989),<br></p>Fórmula:C22H28O3Forma y color:NeatPeso molecular:340.466-Bromo-betamethasone 17,21-Dipropionate
CAS:Producto controlado<p>Stability Hygroscopic<br>Applications 6-Bromo-Betamethasone 17,21-Dipropionate (Betamethasone Dipropionate EP Impurity H) is an impurity of Betamethasone (B327000), a glucocorticoid used as an anti-inflammatory agent.<br>References Ferrante, M.G., et al.: Anal. Profiles Drug Subs., 6, 43 (1977); Li, A., et al.: Chem. Biol. Interact., 142, 7 (2002); Cruz-Monteagudo, M., et al.: Eur. J. Med. Chem., 40, 1030 (2005)<br></p>Fórmula:C28H36BrFO7Forma y color:NeatPeso molecular:583.482-Hydroxy Atorvastatin Calcium Salt
CAS:Producto controlado<p>Applications di(2-Hydroxy Atorvastatin) Calcium Salt is a metabolite of Atorvastatin Calcium Salt (A791750), a selective, competitive HMG-CoA reductase inhibitor. Atorvastatin is the only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglycerides in patients with hypercholesterolemia.<br>References Kearney, A.S., et al.: Pharm. Res., 10, 1461 (1993); Heinonen, T.M., et al.: Clin. Ther., 18, 853 (1996); Whitfield, L.R., et al.: Eur. J. Drug Metab. Pharmacokinet., 25, 97 (2000)<br></p>Fórmula:C66H68CaF2N4O12Forma y color:White To YellowPeso molecular:1187.35Testosterone 17-Hexahydrobenzoate
CAS:Producto controlado<p>Applications Testosterone 17-Hexahydrobenzoate is a metabolite of testosterone (T155000), which is used in biological studies to determine the hemolytic and lipophilic activity of this anabolic steroid.<br>References Biagi, G.L., et al.: J. Med. Chem., 13, 944 (1970); Biagi, G. L., et al.: J. Med. Chem., 18, 873 (1975)<br></p>Fórmula:C26H38O3Forma y color:NeatPeso molecular:398.58Ursodeoxycholic acid
CAS:Pureza:98.0%Forma y color:Solid, White powderPeso molecular:392.57998657226566-Oxo D-(-)-Norgestrel
CAS:Producto controlado<p>Impurity Levonorgestrel EP Impurity J<br>Applications 6-Oxo D-(-)-Norgestrel (Levonorgestrel EP Impurity J) is an impurity of D-(-)-Norgestrel (N689510).<br></p>Fórmula:C21H26O3Forma y color:NeatPeso molecular:326.434-Fluoro-α-(2-methyl-1-oxopropyl)-γ-oxo-N,β-diphenyl-benzenebutanamide
CAS:Producto controlado<p>Impurity Atorvastatin Diketo Amide Impurity<br>Applications An Atorvastatin intermediate. Atorvastatin is a selective, competitive HMG-CoA reductase inhibitor. The only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglycerides in patients with hypercholesterolemia.<br>References Winters, R., et al.: J. Med. Chem., 36, 1735 (1993), Hagmann, W., et al.: Bioorg. Med. Chem. Lett., 10, 1975 (2000), Istvan, E., et al.: Science, 292, 1160 (2001)<br></p>Fórmula:C26H24FNO3Forma y color:White To Off-WhitePeso molecular:417.47(11β,16α)-11-Hydroxy-16-(1-oxobutoxy)-androsta-1,4-diene-3,17-dione
CAS:Fórmula:C23H30O5Forma y color:ColourlessPeso molecular:386.48Norethindrone Acetate
CAS:<p>Applications Progesteron. Norethindrone and acetate in combination with estrogen as contraceptive (oral). It is reasonably anticipated to be a human carcinogen.<br>References Schroff, A. P., et al.: Anal. Profiles Drug Subs., 4, 268 (1975), Singh, H., et al.: Am. J. Obstet. Gynecol., 135, 409 (1979), Toews, M., et al.: Curr. Ther. Res, 41, 509 (1987),<br></p>Fórmula:C22H28O3Forma y color:White To Off-WhitePeso molecular:340.46Ciclesonide 22S-Epimer
CAS:Producto controladoFórmula:C32H44O7Forma y color:NeatPeso molecular:540.688
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