Esteroides y derivados
Los esteroides son compuestos orgánicos que poseen una estructura de cuatro anillos fusionados, conocida como el núcleo esteroídico. Este núcleo puede unirse a varios grupos funcionales que modifican sus propiedades y funciones biológicas. Los esteroides tienen un papel clave en la regulación de procesos metabólicos y hormonales. Se utilizan en medicina para tratar trastornos inflamatorios, autoinmunes y desequilibrios hormonales. Además, algunos derivados esteroides tienen propiedades antiinflamatorias potentes, como los corticosteroides. En terapias específicas, se usan para reducir la inflamación y controlar el dolor en diversas enfermedades.
En CymitQuimica contamos con una variedad de esteroides y sus derivados para investigación y desarrollo farmacéutico.
Se han encontrado 4962 productos de "Esteroides y derivados"
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17β-Estradiol-16,16,17-d3
CAS:Producto controlado<p>Applications Isotope labelled 17β-Estradiol (E888000), which is the major estrogen (1) secreted by the premenopausal ovary (2).Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA), environmental, and food contaminants.<br>References 1. Salole, E. et al.: Anal. Profiles Drug Subs. 1986 15, 23 283-3182. Lievertz, R. et al.: Am. J. Obstet. Gynecol. 1987 May;156(5):1289-93.<br></p>Fórmula:C182H3H21O2Forma y color:NeatPeso molecular:275.40Dexamethasone-d5 Acid Ethyl Ester
Producto controlado<p>Applications Isotope Labelled Dexamethasone Acid Ethyl Ester is a derivative of Dexamethasone (D298800), a glucocorticoid used as an anti-inflammatory agent. Dexamethasone regulates T cell survival, growth, and differentiation. Dexamethasone inhibits the induction of nitric oxide synthase.<br>References Wershil, B.K., et al.: Int. Arch. Allergy Immunol., 107, 323 (1995), Riccardi, C., et al.: Cell Death Diff., 6, 1182 (1999), Llanos, S.L. and Roldan, A.: Bio Cell, 23, 29 (1999)<br></p>Fórmula:C23D5H26FO5Forma y color:NeatPeso molecular:411.5211α-Hydroxy Progesterone
CAS:Producto controlado<p>Applications Progesterone (P755900) metabolite.<br>References Christy H., et al.: J. Steroid Biochem., Mol., Biol., 116, 171 (2009), Peristera, O., et al.: Toxicol., Lett., 189, 219 (2009), Mori, T., et al.: Toxicol., Lett., 186, 123 (2009),<br></p>Fórmula:C21H30O3Forma y color:Off-WhitePeso molecular:330.466-[(1E)-2-[3-(4-Fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]ethenyl]-5,6-dihydro-4-hydroxy-2H-pyran-2-one
CAS:<p>Impurity Fluvastatin EP Impurity E<br>Applications 6-[(1E)-2-[3-(4-Fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]ethenyl]-5,6-dihydro-4-hydroxy-2H-pyran-2-one (Fluvastatin EP Impurity E) is an impurity of Fluvastatin (F601250), a synthetic HMG-CoA reductase inhibitor. Antilipemic.<br>References Yuan, J., et al.: Atherosclerosis, 87, 147 (1991), Tse, F.L.S., et al.: J. Clin. Pharmacol., 32, 630 (1992), Dain, J.G., et al.: Drug Metab. Disposit., 21, 567 (1993)<br></p>Fórmula:C24H22FNO3Forma y color:NeatPeso molecular:391.436β-Hydroxy Budesonide-d8
CAS:Producto controlado<p>Applications A labelled metabolite of Budesonide (B689490), a non-halogenated glucocorticoid related to triamcinolone hexacetonide. Used as an antiinflammatory agent.<br>References Ryrfeldt., A., et a.: J. Steroid Biochem., 10, 317 (1979), Roth, G., et al.: J. Pharm. Sci., 69, 766 (1980), Edsbaecker, S., et al.: Drug Metab. Dispos., 15, 412 (1987),<br></p>Fórmula:C25H26D8O7Pureza:~90%Forma y color:NeatPeso molecular:454.5817β-Estradiol-d3 17-Acetate 3-β-D-Glucuronide
Producto controlado<p>Applications A labelled Estradiol (E888000) derivative.<br></p>Fórmula:C26H31D3O9Forma y color:NeatPeso molecular:493.5622b-Hydroxy Cholesterol
CAS:Producto controlado<p>Applications The 22S-metabolite of Cholesterol (C432501). 22-Hydroxycholesterol inhibits chemokine receptor activity.<br>References Samson, M., et al.: J. Biol. Chem., 272, 24934 (1997), Mackay, C., et al.: Nature Immunol., 2, 95 (2001), Navenot, J., et al.: J. Mol. Biol., 313, 1181 (2001),<br></p>Fórmula:C27H46O2Forma y color:Off White SolidPeso molecular:402.65Fluocortolone
CAS:Producto controlado<p>Applications Fluocortolone is a glucocorticoid used in the treatment of several conditions, including hemorrhoids. Fluocortolone is similar to Fluocortin, but with one less keto group.<br>References Breuer, et al.: Arzneim.-Forsch., 15, 50 (1965), Domenico, et al.: Arzneim.-Forsch., 15, 46 (1965), Gerhards, et al.: Acta Endocrinol., 68, 98 (1971),<br></p>Fórmula:C22H29FO4Forma y color:Off-White To YellowPeso molecular:376.463b,5a,6b-Trihydroxycholestane
CAS:<p>Applications Cholesterol analog. Useful for treatment of hyperlipemia, arteriosclerosis, diabetes, obesity.<br>References Watson, K., et al.: J. Clin. Invest., 93, 2106 (1994), Wada, T., et al.: Circ. Res., 84, 166 (1999), Engelse, M., et al.: Cardiovasc. Res., 52, 281 (2001), Landis, M., et al.: J. Biol. Chem., 277, 4713 (2002),<br></p>Fórmula:C27H48O3Forma y color:NeatPeso molecular:420.674-Hydroxy Atorvastatin Disodium Salt
CAS:<p>Applications A metabolite of Atorvastatin, a selective, competitive HMG-CoA reductase inhibitor. Atorvastatin is the only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglycerides in patients with hypercholesterolemia.<br>References Smith, S., et al.: Am. J. Cardiol., 80, 10H (1997), Jacobsen, W., et al.: Drug Metab. Dispos., 28, 1369 (2000), Istvan, E., et al.: Science, 292, 1160 (2001), Tabernero, L., et al.: J. Biol. Chem., 278, 19933 (2003), Bratton, L., et al.: Bioorg. Med. Chem., 15, 5576 (2007),<br></p>Fórmula:C33H33FN2Na2O6Forma y color:White To BrownPeso molecular:618.603α,5β-Tetrahydro Norgestrel
CAS:Producto controlado<p>Applications The major metabolite of the progestational agent Norgestrel (N689500).<br>References DeJongh, D.C. et al.: Steroids, 11, 649 (1968); Uniyal, J.P. et al.: Acta Endocrinol., 84, 155 (1977); Sisenwine, S.F. et al.: Drug Metab. Disp., 7, 1 (1979);<br></p>Fórmula:C21H32O2Forma y color:NeatPeso molecular:316.48(20S)-Dexamethasone Epimeric Glycolic Acid
CAS:Fórmula:C22H29FO6Forma y color:NeatPeso molecular:408.46Dexamethasone 21-Formate
CAS:Producto controlado<p>Applications Dexamethasone 21-Formate is a metabolite of Dexamethasone.<br>References Minagawa, K., et al.: Steroids, 47, 175 (1986), Murray, G., et al.: Br. J. Clin. Pharmacol., 25, 465 (1988), Ravichandran, K., et al.: Science, 1993, 261, 731 (1993),<br></p>Fórmula:C23H29FO6Forma y color:NeatPeso molecular:420.47Finasteride Carboxylic Acid
CAS:Producto controladoFórmula:C23H34N2O4Forma y color:Light Yellow SolidPeso molecular:402.5311-Dehydrodexamethasone
CAS:Producto controladoFórmula:C22H27FO5Forma y color:NeatPeso molecular:390.4452(3S,3aS,5aS,6R,9aS,9bS)-3-[[(1,1-Dimethylethyl)amino]carbonyl]dodecahydro-3a,6-dimethyl-7-oxo-1H-benz[e]indene-6-propanoic Acid
CAS:Producto controladoFórmula:C23H37NO4Forma y color:NeatPeso molecular:391.544Estradiol 3-Sulfate 17β-Glucuronide Dipotassium
CAS:Producto controlado<p>Applications A 17β-Estradiol (E888000) metabolite.<br>References Gerk, P., et al.: Drug Metab. Disposition, 32, 1139 (2004), Antignac, J., et al.: Steroids, 70, 205 (2005), Cole, T., et al.: J. Fish Biol., 68, 661 (2006), Hutchins, S., et al.: Env. Sci. Technol., 41, 7192 (2007),<br></p>Fórmula:C24H30O11S·2KForma y color:White To Off-WhitePeso molecular:604.75di(2-Hydroxy Atorvastatin-d5) Calcium Salt
CAS:Producto controlado<p>Applications di(2-Hydroxy Atorvastatin-d5) Calcium Salt is the labeled analogue of di(2-Hydroxy Atorvastatin) Calcium Salt (H828930), a metabolite of Atorvastatin Calcium Salt (A791750), a selective, competitive HMG-CoA reductase inhibitor. Atorvastatin is the only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglycerides in patients with hypercholesterolemia.<br>References Kearney, A.S., et al.: Pharm. Res., 10, 1461 (1993); Heinonen, T.M., et al.: Clin. Ther., 18, 853 (1996); Whitfield, L.R., et al.: Eur. J. Drug Metab. Pharmacokinet., 25, 97 (2000)<br></p>Fórmula:C66H58D10CaF2N4O12Forma y color:NeatPeso molecular:1197.424-Methoxy-d3 17β-estradiol (>90%)
CAS:Producto controlado<p>Applications A labelled metabolite of 17β-Estradiol.<br>References Cushman, M., et al.: J. Med. Chem., 38, 2041 (1995), D’Amato, R.J., et al.: Proc. Natl. Acad. Sci. USA, 91, 3964 (1994), Forsis, T., et al.: Nature, 368, 237 (1994)<br></p>Fórmula:C19H23D3O3Pureza:>90%Forma y color:NeatPeso molecular:305.43Zilpaterol-d7
CAS:Producto controlado<p>Applications b-Adrenergic agonist. Zipaterol, is used to promote growth. Zilpaterol is used to increase the size of cattle.<br>References Shelver, W.L., et al.: J. Agric. Food Chem., 52, 2159 (2004),<br></p>Fórmula:C14H12D7N3O2Forma y color:Light BrownPeso molecular:268.36(15S)-Latanoprost
CAS:<p>Impurity Latanoprost USP Related Compound B<br>Applications An impurity of commercially prepared Latanoprost (L177280). Latanoprost USP Related Compound B.<br>References Resul, B., et al.: J. Med. Chem., 36, 2242 (1993),<br></p>Fórmula:C26H40O5Forma y color:ColourlessPeso molecular:432.59(3β)-Cholesta-4,6-dien-3-ol
CAS:<p>Applications (3β)-Cholesta-4,6-dien-3-ol is a Cholesterol (C432501) and Cholestane (C431700) derivative which has the potential to act as an antiinflammatory and antifungal compound.<br>References Felicio, R. et al.: J. Pharm. Biomed. Anal., 52, 763 (2010); Rosin, Z., et al.: Physiol. Chem., 124, 282 (1923), Schoenheimer, et al.: J. Biol. Chem., 105, 355 (1934), Gemant, et al.: Life Sci., 1, 233 (1962), Johnson, K., et al.: 4, 457 (1964),<br></p>Fórmula:C27H44OForma y color:NeatPeso molecular:384.6421-Dehydro Budesonide
CAS:Producto controlado<p>Impurity Budesonide EP Impurity D<br>Stability Hygroscopic<br>Applications 21-Dehydro Budesonide (Budesonide EP Impurity D) is a Budesonide (B689490) impurity.<br>References Backes, S., et al.: Drug Metab. Rev., 34, 157 (2002), Vermeer, H., et al.: Clin. Endocrinol., 59, 49 (2003), Assi, K., et al.: J. Pharm. Biomed. Anal., 41, 325 (2006),<br></p>Fórmula:C25H32O6Forma y color:NeatPeso molecular:428.52Dienogest
CAS:Producto controlado<p>Applications Derivative of 19-Nortestosterone. In combination with estrogen as oral contraceptive. Progestogen.<br>References Hubner, M., et al.: Arzneim.-Forsch., 30, 401 (1980), Spona, J., et al.: Contraception, 56, 185 (1997), Foster, R.H., et al.: Drugs, 56, 825 (1998),<br></p>Fórmula:C20H25NO2Forma y color:NeatPeso molecular:311.42(R)-Ostarine
CAS:Producto controlado<p>Applications The R-enantiomer of nonsteroidal selective androgen receptor modulator (SARM) Ostarine (O703500).<br></p>Fórmula:C19H14F3N3O3Forma y color:Light Orange Colour SolidPeso molecular:389.333-epi-Pregnenolone
CAS:Producto controlado<p>Applications An epimer of Pregnenolone (P712200), a GABAA antagonist and increases neurogenesis in the hippocampus.<br>References Li, W. et al.: J, Pharmacol. Exp. Therap., 323, 236 (2007); Sunol, C. et al.: J. Med. Chem., 49, 3225 (2006);<br></p>Fórmula:C21H32O2Forma y color:NeatPeso molecular:316.482-Hydroxymethylene Ethisterone
CAS:Producto controlado<p>Applications A derivative of Danazol (D145000).<br>References Manson, A.J., et al.: J. Med. Chem., 6, 1 (1963), Jordan, V.C., et al.: Endocrinology, 124, 1717 (1989),<br></p>Fórmula:C22H28O3Forma y color:NeatPeso molecular:340.46Isoflupredone Acetate
CAS:Producto controlado<p>Applications An anti-inflammatory drug used in veterinary medicine. It is a corticosteroid with both glucocorticoid and mineralocorticoid activity and has been shown to increase the frequency of severe hypokalemia in healthy cows.<br>References Coffer, N.Y. et al.: Am. J. Vet. Res., 67, 1244 (2006); Seifi, H.A. et al.: J. Diary Sci., 90, 4181 (2007);<br></p>Fórmula:C23H29FO6Forma y color:Off-WhitePeso molecular:420.47δ7,9(11)-Dexamethasone
CAS:<p>Stability Hygroscopic<br>Applications Dexamethasone (D298800) process impurity.<br></p>Fórmula:C22H26O4Forma y color:NeatPeso molecular:354.443(R,S)-Hydroxy Desogestrel
CAS:Producto controlado<p>Applications A metabolite of Desogestrel.<br>References Back, D., et al.: Br. J. Clin. Pharmacol., 26, 23 (1988), Wienkers, L., et al.: Drug Metab. Dispos., 1990, 24, 610 (1990), Bourrie, M., et al.: J. Pharmacol. Exp. Ther., 277, 321 (1996), Ono, S., et al.: Xenobiotica, 26, 681 (1996),<br></p>Fórmula:C22H30O2Forma y color:NeatPeso molecular:326.47Deflazacort
CAS:Producto controlado<p>Applications A systemic corticosteroid. A derivative of prednisolone. Used for rheumatoid arthritis and lupus.<br>References Nathansohn, G., et al.: J. Med. Chem., 10,799 (1967), Schiatti, P., et al.: Arzneim. Forsch., 30, 1543 (1980), Cavall-Perin, P., et al.: Eur. J. Clin. Pharmacol., 26, 357 (1984), Imbimbo, B., et al.: Adv. Exp. Med. Biol., 171, 241 (1984),<br></p>Fórmula:C25H31NO6Forma y color:NeatPeso molecular:441.52(aR,1S,3S,4R)-a,4-Dimethyl-2-oxo-3-(3-oxobutyl)-cyclohexaneacetic Acid
CAS:Producto controlado<p>Stability Hygroscopic, Unstable in Solution<br>Applications (αR,1S,3S,4R)-α,4-Dimethyl-2-oxo-3-(3-oxobutyl)-cyclohexaneacetic Acid is an impurity of Artemisin (A777500), an active antimalarial constituent of the tradional Chinese medicinal herb Artemisia annua L., Compositae, which has been known for almost 2000 years as Qinghao. Antimalarial.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Klayman, D.L., et al.: Science, 228, 1049 (1985), Price, R.N., et al.: Expert Opin. Invest. Drugs, 9, 1815 (2000), Meshnick, S.R., et al.: Int. J., Parasitol., 32, 1655 (2002),<br></p>Fórmula:C14H22O4Forma y color:NeatPeso molecular:254.32Ulipristal-d3
CAS:Producto controlado<p>Applications Labelled Ulipristal (U700800). Ulipristal is a selective progesterone receptor modulator. Ulipristal is used during pregnancy.<br>References Gronemeijer, H., et al.: J. Steroid Biochem., 40, 271 (1991), Spitz, I., et al.: Contraception, 48, 403 (1993), Conneely, O., et al.: Steroids, 68, 771 (2003), Chwalisz, K., et al.: Endocr. Rev., 26, 423 (2005),<br></p>Fórmula:C282H3H32NO3Forma y color:NeatPeso molecular:433.586-Bromo-betamethasone 17,21-Dipropionate
CAS:Producto controlado<p>Stability Hygroscopic<br>Applications 6-Bromo-Betamethasone 17,21-Dipropionate (Betamethasone Dipropionate EP Impurity H) is an impurity of Betamethasone (B327000), a glucocorticoid used as an anti-inflammatory agent.<br>References Ferrante, M.G., et al.: Anal. Profiles Drug Subs., 6, 43 (1977); Li, A., et al.: Chem. Biol. Interact., 142, 7 (2002); Cruz-Monteagudo, M., et al.: Eur. J. Med. Chem., 40, 1030 (2005)<br></p>Fórmula:C28H36BrFO7Forma y color:NeatPeso molecular:583.486α-Hydroxy Androstenedione
CAS:Producto controlado<p>Applications A metabolite of Androstenedione (A637550).<br>References Gazdar, A., et al.: Cancer Res., 50, 5488 (1990), Levesque, J., et al.: Steroids, 70, 305 (2005), Lootens, L., et al.: Drug Metab. Dispos., 37, 2367 (2009),<br></p>Fórmula:C19H26O3Forma y color:NeatPeso molecular:302.413-Keto Fluvastatin Sodium Salt
CAS:Producto controlado<p>Stability Light Sensitive<br>Applications An impurity of Fluvastatin.<br></p>Fórmula:C24H23FNO4·NaForma y color:NeatPeso molecular:431.43N-Demethyl Mifepristone
CAS:<p>Applications A metabolite of Mifepristone (M343975).<br>References Ringler, I., et al.: Metabolism, 13, 37 (1964), Gagne, D., et al.: J. Steroid. Biochem., 25, 315 (1986), Jang, G., et al.: Biochem. Pharmacol., 52, 753 (1996), Hild, S., et al.: Hum. Reprod., 15, 822 (2000), Gainer, E., et al.: Steroids, 68, 1005 (2003),<br></p>Fórmula:C28H33NO2Forma y color:NeatPeso molecular:415.57Estradiol Enanthate
CAS:<p>Applications Estradiol Enanthate has been used as an injectable contraceptive.<br>References Coutinho, E.M., et. al.: Contraception, 73, 249 (2006)<br></p>Fórmula:C25H36O3Forma y color:BeigePeso molecular:384.555β-Finasteride
CAS:Producto controlado<p>Applications 5β-Finasteride is an azasteroid and 5β-isomeric impurity of Finasteride (F342000).<br>References Cendrowska, I. et al.: J. Liq. Chrom. Rel. Technol., 22, 2259 (1999);<br></p>Fórmula:C23H36N2O2Forma y color:Off-WhitePeso molecular:372.5425-Hydroxyvitamin D3 3-Hemisuccinate
CAS:Producto controlado<p>Stability Light Sensitive, Temperature Sensitive<br>Applications 25-Hydroxyvitamin D3 3-Hemisuccinate is a conjugate of 5-Hydroxyvitamin D3 (C125700), the principal circulating form of vitamin D3, formed in the liver by hydroxylation at C-25. Calcium regulator. Also used in the preparation and synthesis of antisera to be used in the immunoassay of 25-Hydroxyvitamin D3.<br>References Morii, et al.: Arch. Biochem. Biophys., 120, 513 (1967), Blunt, et al.: Biochemistry, 7, 3317 (1968), Liu, et al.: Science, 311, 1770 (2006),<br></p>Fórmula:C31H48O5Forma y color:NeatPeso molecular:500.71Fluorometholone
CAS:Producto controlado<p>Applications Fluorometholone is a glucocorticoid; anti-inflammatory.<br>References Kupferman, A., et al.: Arch. Ophthlmol., 640, 100 (1982), Tokunaga H., et al.: Chem. Pharm. Bull., 32, 4012 (1984),<br></p>Fórmula:C22H29FO4Forma y color:White To Off-WhitePeso molecular:376.4621-Dehydro Dexamethasone Hydrate
CAS:Fórmula:C22H27FO5·H2OForma y color:White To Light YellowPeso molecular:408.46trans-Latanoprost Acid
CAS:Producto controlado<p>Applications The trans metabolite of Latanoprost (L177280), Prostaglandin analog.<br>References Botchkareva, N., et al.: FASEB J., 115, 645 (2001),<br></p>Fórmula:C23H34O5Forma y color:NeatPeso molecular:390.513Betamethasone-∆17,20 21-Aldehyde(Mixture of Isomers)
CAS:Producto controlado<p>Applications A degradation and metabolic intermediate of Betamethasone (B3270000).<br></p>Fórmula:C22H27FO4Forma y color:NeatPeso molecular:374.45δ7-Stigmasterol
CAS:Producto controlado<p>Applications Δ7-Stigmasterol is an analog of Stigmasterol (S686750); a plant sterol that is used as a precursor in the synthesis of progesterone.<br>References Han, P., et al.: Biotechnol. App. Biochem., 54, 105 (2009); Matsunaga, I., et al.: Anal. Biochem., 393, 222 (2009); Huang, C., et al.: Plant Physiol., 150, 1192 (2009)<br></p>Fórmula:C29H46OForma y color:White To Light YellowPeso molecular:410.67Fulvestrant
CAS:Producto controladoFórmula:C32H47F5O3SForma y color:White To Off-WhitePeso molecular:606.7717α-Hydroxy Progesterone
CAS:Producto controlado<p>Impurity Progesterone 17?-Hydroxy Impurity<br>Applications 17α-Hydroxy Progesterone is a metabolite of Progesterone (P755900). It was isolated from adrenal glands.<br>References Pfiffner, N., et al.: J. Biol. Chem., 132, 459 (1940), Florey, K., et al.: Anal. Profiles Drug Subs.,4, 209 (1975),<br></p>Fórmula:C21H30O3Forma y color:Off-WhitePeso molecular:330.46
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