Esteroides y derivados
Los esteroides son compuestos orgánicos que poseen una estructura de cuatro anillos fusionados, conocida como el núcleo esteroídico. Este núcleo puede unirse a varios grupos funcionales que modifican sus propiedades y funciones biológicas. Los esteroides tienen un papel clave en la regulación de procesos metabólicos y hormonales. Se utilizan en medicina para tratar trastornos inflamatorios, autoinmunes y desequilibrios hormonales. Además, algunos derivados esteroides tienen propiedades antiinflamatorias potentes, como los corticosteroides. En terapias específicas, se usan para reducir la inflamación y controlar el dolor en diversas enfermedades.
En CymitQuimica contamos con una variedad de esteroides y sus derivados para investigación y desarrollo farmacéutico.
Se han encontrado 4949 productos de "Esteroides y derivados"
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17β-Dihydro Equilin-16,16,17-d3
CAS:Producto controlado<p>Applications A labelled metabolite of Equilin (E592800).<br>References Enmark, E., et al.: J. Clin. Endocrinol. Metab., 82, 4258 (1997), Wang, Z., et al.: J. Med. Chem., 43, 2419 (2000), Jiang, X., et al.: Steroids, 71, 334 (2006),<br></p>Fórmula:C182H3H17O2Forma y color:NeatPeso molecular:271.37δ6-Fulvestrant
CAS:Producto controlado<p>Impurity Fulvestrant Impurity E;<br>Applications Fulvestrant (F862500) impurity E.<br></p>Fórmula:C32H45F5O3SForma y color:NeatPeso molecular:604.75Bexarotene-13C4
CAS:Producto controlado<p>Applications Labelled Bexarotene (B336750). Used as an antineoplastic. A selective retinoid X receptor (RXR) agonist.<br>References Boehm, M.F., et al.: J. Med. Che., 37,2930 (1994), Gottardis, M.M., et al.: Cancer Res., 56, 5566 (1996), Mukherjee, R., et al.: Nature, 386, 407 (1997), Miller, V.A., et al.: J. Clin. Oncol., 15, 790 (1997)<br></p>Fórmula:C4C20H28O2Forma y color:NeatPeso molecular:352.45Dexamethasone Acetate Impurity E
CAS:<p>Applications Dexamethasone Acetate Impurity E is a pregn-4-ene derivative used in the preparation of antiallergic and antiinflammatory drugs.<br>References Nedelec, L., et al.: Ger. Offen. (1978)<br></p>Fórmula:C24H33FO6Forma y color:NeatPeso molecular:436.51Atorvastatin-d5 tert-Butyl Ester
CAS:Producto controlado<p>Applications Atorvastatin-d5 tert-Butyl Ester is the labeled analogue of Atorvastatin tert-Butyl Ester (A791740), an impurity arising in the synthesis of Atorvastatin (A791750), a selective, competitive HMG-CoA reductase inhibitor. Atorvastatin is the only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglycerides in patients with hypercholesterolemia.<br>References Kearney, A.S., et al.: Pharm. Res., 10, 1461 (1993); Heinonen, T.M., et al.: Clin. Ther., 18, 853 (1996); Whitfield, L.R., et al.: Eur. J. Drug Metab. Pharmacokinet., 25, 97 (2000)<br></p>Fórmula:C37H38D5FN2O5Forma y color:NeatPeso molecular:619.78Deflazacort-d3 (Major)
CAS:Producto controladoFórmula:C25H28D3NO6Forma y color:NeatPeso molecular:444.54Ulipristal
CAS:Producto controlado<p>Applications Ulipristal is a selective progesterone receptor modulator. Ulipristal is used as an emergency contraceptive.<br>References Gronemeijer, H., et al.: J. Steroid Biochem., 40, 271 (1991), Spitz, I., et al.: Contraception, 48, 403 (1993), Conneely, O., et al.: Steroids, 68, 771 (2003), Chwalisz, K., et al.: Endocr. Rev., 26, 423 (2005),<br></p>Fórmula:C28H35NO3Forma y color:NeatPeso molecular:433.58Equilin 3-O-β-D-Glucuronide Sodium Salt
CAS:Fórmula:C24H27NaO8Forma y color:NeatPeso molecular:466.46Testosterone-16,16,17-d3 3-Phenylpropionate
CAS:Producto controlado<p>Applications Testosterone-16,16,17-d3 17-Phenylpropionate, is the labeled analogue of Testosterone 17-Phenylpropionate (T155150), a Testosterone ester being misused by athletes in an attempt to improve sports performance. It can also be used as a therapy in glucocorticoid-treated patients to increase the circulating testosterone concentration.<br>References Shackleton, C. H. L., et al.: Steroids, 62 (7), 523 (1997); Reid, I. R., et al.: Archives Internal Med., 156 (11), 1173 (1996);<br></p>Fórmula:C28H33D3O3Forma y color:NeatPeso molecular:423.6016α-Hydroxypregna-4,9(11)-diene-3,20-dione
Producto controlado<p>Applications 16α-Hydroxypregna-4,9(11)-diene-3,20-dione is an intermediate in the synthesis of 16-Hydroxycorticosterone 20-Hydroxy-21-Acid (H918430), an oxidized derivative of corticosterone (C695700).<br>References Allen, G.R., et al.: J. Am. Chem. Soc., 81, 4968 (1959);<br></p>Fórmula:C21H28O3Forma y color:NeatPeso molecular:328.45Estriol 3,16a,17b-Triacetate
CAS:Producto controlado<p>Applications Estriol 3,16α,17β-Triacetate is a triacetate derivative of Estriol (E888960) with contraceptive activity.<br>References Wotiz, H.H., et al.: J. Reprod. Fertil., 26, 363 (1971)<br></p>Fórmula:C24H30O6Forma y color:NeatPeso molecular:414.496b-Chloro-7a-hydroxy-6,7-dihydro Cyproterone Acetate
CAS:Producto controlado<p>(1β,2β,6β-7α)-17-(Acetyloxy)-6-chloro-1,2-dihydro-7-hydroxy<br>-3'H-cyclopropa[1,2]pregna-1,4-diene-3,20-dione; 6β-Chloro<br>-1β,2β-dihydro-7α,17-dihydroxy-3'Hcyclopropa[1,2]pregna-1,4-diene-3,20-dione 17-Acetate;<br>Cyproterone Acetate EP Impurity G</p>Fórmula:C24H31ClO5Forma y color:NeatPeso molecular:434.9533-Oxo-4-aza-5-androstene-17β-carboxylic Acid
CAS:Producto controladoFórmula:C19H27NO3Forma y color:NeatPeso molecular:317.42Testosterone-d8
CAS:Producto controlado<p>Applications Labelled Testosterone (T155000). Principal hormone of the testes, produced by the interstitial cells. Major circulating androgen; converted by 5α-reductase in androgen-dependent target tissues to 5α-dehydrotestosterone which is required for normal male sexual differentiation. Also converted by aromatization to Estradiol.Controlled substance (anabolic steroid). Androgen.<br>References McFarland, K., et al.: Science, 245, 494 (1989), Heckert, L., et al.: Mol. Endocrinol., 12, 1499 (1998), Themmen, A., et al.: Endocr. Rev. 21, 551 (2000), Kumar, R., et al.: Biol. Reprod., 65, 710 (2001),<br></p>Fórmula:C19H20D8O2Forma y color:White To Off-WhitePeso molecular:296.473-O-Benzyl Estriol
CAS:Producto controlado<p>Applications Protected Estriol.<br>References Gohil, V., et al.: Nat. Biotechnol., 28, 249 (2010),<br></p>Fórmula:C25H30O3Forma y color:NeatPeso molecular:378.5021-Butyryloxy Budesonide
<p>Applications 21-Butyryloxy Budesonide is a derivative of Budesonide (B689490), a non-halogenated glucocorticoid related to triamcinolone hexacetonide.<br>References Ryrfeldt., A., et a.: J. Steroid Biochem., 10, 317 (1979); Roth, G., et al.: J. Pharm. Sci., 69, 766 (1980); Clissold, S.P., et al.: Drugs, 28, 485 (1984)<br></p>Fórmula:C29H40O7Forma y color:NeatPeso molecular:500.626a-9-Difluoroprednisolone-17-Carboxylate
CAS:Producto controlado<p>Stability Hygroscopic<br>Applications 6α-9-Difluoroprednisolone-17-Carboxylate is an impurity of 6α,9α-Difluoroprednisolone (D446290), shown to increase metastases and increase glucocorticoid activity in C57/BL6 mice.<br>References Albert, D., Zeidman, I.: Cancer Res., 22, 1297 (1962)<br></p>Fórmula:C20H24F2O5Forma y color:NeatPeso molecular:382.4Digitoxigenin Mono-β-D-digitoxoside
CAS:Producto controladoFórmula:C29H44O7Forma y color:White To Off-WhitePeso molecular:504.662,2-Dibromo-1-(4-fluorophenyl)-2-phenylethanone
Producto controladoFórmula:C14H9Br2FOForma y color:NeatPeso molecular:372.03Fluocinolone Acetonide-13C3
CAS:Producto controladoFórmula:C2113C3H30F2O6Forma y color:NeatPeso molecular:455.47E-Ospemifene
CAS:Producto controlado<p>Applications E-Ospemifene is the E-isomer of Ospemifene (O703000) and is useful for lowering serum cholesterol. It acts as a antiatherosclerotic and is also estrogen-like.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Sodervall, M., et al.: PCT Int. Appl. WO 9942427 A1 19990826. Aug 26, 1999<br></p>Fórmula:C24H23ClO2Forma y color:NeatPeso molecular:378.89a,a,a-Trifluorotoluene
CAS:Producto controlado<p>Applications α,α,α-Trifluorotoluene, is used as a specialty solvent in organic synthesis and an intermediate in the production of pesticides and pharmaceuticals.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Skelly, P. D., et al.: Handbook for Critical Cleaning, 1, 191 (2011);<br></p>Fórmula:C7H5F3Forma y color:ColourlessPeso molecular:146.1123-Hydroxybudesonide
CAS:Producto controlado<p>Applications 23-Hydroxybudesonide is an metabolite of budesonide (B689490), a non-halogenated glucocorticoid related to triamcinolone hexacetonide. Used as an antiinflammatory agent.<br>References Edsbaecker, S., et al.: Drug. Metabol. Dispostion., 15, 403 (1987); Moore, C.D., et al.: Drug. Metabolism. Disposition., 41, 379 (2013);<br></p>Fórmula:C25H34O7Forma y color:NeatPeso molecular:446.5311b-Hydroxy Etiocholanolone
CAS:Producto controlado<p>Applications A metabolite of Etiocholanolone.<br>References Eriksson, H., et al.: Eur. J. Biochem., 15, 132 (1970), Cook, D., et al.: Endocrinology, 93, 1019 (1973),<br></p>Fórmula:C19H30O3Forma y color:White To Off-WhitePeso molecular:306.446β,17α-Dihydroxyprogesterone
CAS:Producto controladoFórmula:C21H30O4Forma y color:NeatPeso molecular:346.46Tetrahydrocortisol 21-Acetate
CAS:Producto controlado<p>Applications Cortisol derivative. A potential corticoid metabolite.<br>References Okihara, R. et al.; Chem. Pharm. Bull. 58, 344 (2010); Hosoda, H. et al.; Chem. Pharm. Bull. 32, 4023 (1984)<br></p>Fórmula:C23H36O6Forma y color:NeatPeso molecular:408.5320β-Dihydrocortisone
CAS:Producto controlado<p>Applications 20β-Dihydrocortisone is a metabolite of Cortisol (H714615), a steroid hormone, more specifically a glucocorticoid, produced by the zona fasciculata of the adrenal gland. Cortisol is released in response to stress and a low level of blood glucocorticoids. Its primary functions are to increase blood sugar through gluconeogenesis; suppress the immune system; and aid in fat, protein and carbohydrate metabolism.<br>References Reach, G., et. al.: Steroids, 30, 621 (1977); Vigore, L., et al.: Cancer Ther., 6, 699 (2008); Puurunen, J., et al.: J. Clin. Endocrinol. Metab., 94, 1973 (2009); Lemos, D., et al.: J. Endocrinol., 201, 275 (2009); Chen, S., et al.: Am. J. Physiol., 296 (2009)<br></p>Fórmula:C21H30O5Forma y color:NeatPeso molecular:362.46a-Epoxyabiraterone Acetate
CAS:Producto controlado<p>Stability Hygroscopic<br>Applications α-Epoxyabiraterone Acetate is an impurity of Abiraterone (A108490), a steroidal cytochrome P 450 17α-hydroxylase-17,20-lyase inhibitor (CYP17), is currently undergoing phase II clinical trials as a potential drug for the treatment of androgen-dependent prostate cancer.<br>References Denis, L., et al.: Cancer, 72, 3888 (1993); Potter, G.A., et al.: J. Med. Chem., 38, 2463 (1995); Denmeade, S., et al.: Nat. Rev., 2, 389(2002); Scher, H., et al.: J. Clin. Oncol., 23, 8253 (2005)<br></p>Fórmula:C26H33NO3Forma y color:NeatPeso molecular:407.55Des[[N-(1,1-Dimethylethyl)amino]carbonyl] 17-(Propionyl) Finasteride
CAS:Producto controlado<p>Applications An impurity of Finasteride (F342000).<br></p>Fórmula:C21H31NO2Forma y color:NeatPeso molecular:329.489-Dehydroestrone
CAS:Producto controladoFórmula:C18H20O2Forma y color:White To Off-WhitePeso molecular:268.356-Dehydro Nandrolone Acetate
CAS:Producto controladoFórmula:C20H26O3Forma y color:NeatPeso molecular:314.426b-Methyl Fluorometholone
CAS:Producto controlado<p>Stability Not stable in Acidic or basic condition<br>Applications 6β-Methyl Fluorometholone is an impurity in the synthesis of Fluorometholone (F593145), a glucocorticoid; anti-inflammatory.<br>References Kupferman, A., et al.: Arch. Ophthlmol., 640, 100 (1982), Tokunaga H., et al.: Chem. Pharm. Bull., 32, 4012 (1984),<br></p>Fórmula:C22H29FO4Forma y color:NeatPeso molecular:376.46Cholesterol 5α,6α-Epoxide
CAS:Producto controlado<p>Applications Cholesterol 5alpha,6alpha-epoxide is used in the generation of oxysterols and in the studies of the biological significance of oxysterols.<br>References Lizard, G., et al.: Eur. J. Lipid Sci. Technol., 118, 135 (2016); Sabolova, M., et al.: J. Sci. Food Agric., 97, 5092 (2017); Bezine, M., et al.: Biochimie (2018)<br></p>Fórmula:C27H46O2Forma y color:NeatPeso molecular:402.65Atorvastatin Lactone Diepoxide(Mixture of Diastereomers)
CAS:Producto controlado<p>Stability Light Sensitive, Temperature Sensitive<br>Applications An Atorvastatin (A791750) derivative which have improved stability.<br></p>Fórmula:C33H33FN2O6Forma y color:NeatPeso molecular:572.62Epoxy Metradiene
CAS:Producto controlado<p>Applications Epoxy Metradiene is an impurity from synthesis of Fluorometholone (F593145),a glucocorticoid; anti-inflammatory.<br>References Kupferman, A., et al.: Arch. Ophthlmol., 640, 100 (1982); Tokunaga H., et al.: Chem. Pharm. Bull., 32, 4012 (1984);<br></p>Fórmula:C22H28O4Forma y color:NeatPeso molecular:356.4620-Dihydroprogesterone Acetate
CAS:Producto controlado<p>Impurity Progesterone EP Impurity E<br>Applications 20-Dihydroprogesterone Acetate (Progesterone EP Impurity E) is an analogue of Progesterone (P755900), a steroid used in cardiovascular and menopausal studies.<br>References Grodstein, F. et al.: New. Eng. J. Med., 335, 453 (1996); Cushman, M. et al.: Circulation, 100, 717 (1999);<br></p>Fórmula:C23H34O3Forma y color:NeatPeso molecular:358.51Finasteride Carboxaldehyde
CAS:Producto controlado<p>Applications A metabolite of Finasteride (F342000) in human bile (M2 metabolite).<br>References Faller, B., et al.: Biochemistry, 32, 5705 (1993), Carlin, J.R., Drug Metab. Dispos., 25, 100 (1997), Bergman, E., et al.: Eur. J. Pharm. Sci., 29, 205 (2006),<br></p>Fórmula:C23H34N2O3Forma y color:NeatPeso molecular:386.53Boldione (1 mg/ml in Acetonitrile)
CAS:Producto controladoFórmula:C19H24O2Forma y color:Single SolutionPeso molecular:284.39Testosterone 17-O-Acetate-d3 (1mg/ml in Acetonitrile)
CAS:Producto controladoFórmula:C21H27D3O3Forma y color:ColourlessPeso molecular:333.48Testosterone Cypionate-d3 (1 mg/ml in Acetonitrile)
CAS:Producto controladoFórmula:C27D3H37O3Forma y color:Single SolutionPeso molecular:415.62Betamethasone 21-Mesylate (>90%)
CAS:Producto controladoFórmula:C23H31FO7SPureza:>90%Forma y color:NeatPeso molecular:470.55Carbenoxolone
CAS:Producto controlado<p>Applications Carbenoxolone<br></p>Fórmula:C34H50O7Forma y color:NeatPeso molecular:570.76Betamethasone 21-Phosphate Biotin (>85%)
Producto controladoFórmula:C34H49FN3O10PSPureza:>85%Forma y color:NeatPeso molecular:741.81Prednisolone (1 mg/mL in Methanol)
CAS:Producto controladoFórmula:C21H28O5Forma y color:ColourlessPeso molecular:360.44(3aR,4R,5R,6aS)-4-((S,E)-3-Hydroxy-5-phenylpent-1-enyl)hexahydro-2H-cyclopenta[b]furan-2,5-diol (Bimatoprost Impurity)
CAS:Producto controladoFórmula:C18H24O4Forma y color:NeatPeso molecular:304.3825-Hydroxy Cholesterol-d6
CAS:Producto controlado<p>Applications 25-Hydroxy Cholesterol-d6, is the labeled analogue of 25-Hydroxy Cholesterol (H918030), which is an oxygenated derivative of Cholesterol (C432501); an oxysterol. An inhibitor of human immunodeficiency virus replication in vitro. It also induces apoptosis in human monocytic cell lines as well as inducing apoptosis in CEM cells associated with negative regulation of c-Myc.<br>References Aupeix, K. et al.: Immunobiology, 194, 415 (1995); Moog, C. et al.: Antivir. Chem, Chemother., 9, 491 (1998); Ayala-Torres, S. et al.: Exp. Cell Res., 246, 193 (1999);<br></p>Fórmula:C272H6H40O2Forma y color:NeatPeso molecular:408.69(3E)-17-Deacetylnorgestimate
CAS:<p>Applications E-17-Deacetylnorgestimate is a metabolite of Norgestimate. A contraceptive for birth control used by women.Note- The oxime isomerizes when: 1) Heated in any solvent or heating the crystalline form 2) Dissolved in MeOH at room temperature very quickly 3) Dissolved in acetone or CHCl3 at room temperature in a couple of hours at room temperature4) In EtOAc or EtOAc/isooctane over a couple of days at RT. It is stable in the crystalline form.<br>References Phillips, A., et al.: Steroids, 55, 373 (1990); Rabiolo, A., et al.: Arch. Gynecol. Obstet., 294, 1317 (2016)<br></p>Fórmula:C21H29NO2Forma y color:Off-WhitePeso molecular:327.46Betamethasone 17-Propionate 21-Mesylate
CAS:<p>Impurity Clobetasol Propionate EP Impurity I<br>Stability Hygroscopic<br>Applications Betamethasone 17-Propionate 21-Mesylate (Clobetasol Propionate EP Impurity I) is the 21-mesylate analogue of Betamethasone 17-Acetate (B327015) with antiinflammatory activity.<br>References Mitsukuchi, M. et al.: Chem. Pharm. Bull., 37, 3286 (1989);<br></p>Fórmula:C26H35FO8SForma y color:NeatPeso molecular:526.61
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![(3aR,4R,5R,6aS)-4-((S,E)-3-Hydroxy-5-phenylpent-1-enyl)hexahydro-2H-cyclopenta[b]furan-2,5-diol (B…](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTR%2Fthumb-webp%2FH294735.webp&w=3840&q=75)
