Fosfatos y Fosfonatos Orgánicos
Los fosfatos orgánicos son compuestos que contienen un grupo fosfato (-PO₄) unido a un átomo de carbono en una estructura orgánica, generalmente en combinación con alcoholes, ácidos o aminas. Estos compuestos se utilizan en la formulación de APIs para mejorar la solubilidad, estabilidad y biodisponibilidad de los principios activos. Los fosfatos orgánicos también tienen aplicaciones en la liberación controlada de fármacos y en la mejora de la absorción de ciertos medicamentos. Los fosfonatos orgánicos contienen un grupo fosfonato (-PO₃H₂) en el que el átomo de fósforo está unido a un átomo de carbono y dos grupos oxígeno. Estos compuestos tienen propiedades importantes en la farmacología, especialmente en la inhibición de enzimas o en la modulación de procesos bioquímicos. Los fosfonatos orgánicos se utilizan en la producción de APIs que actúan sobre el metabolismo óseo, infecciones bacterianas o en tratamientos antivirales debido a sus efectos biológicos específicos.
En CymitQuimica contamos con fosfatos y fosfonatos orgánicos para investigación en química médica, bioquímica y desarrollo de formulaciones avanzadas.
Se han encontrado 1202 productos de "Fosfatos y Fosfonatos Orgánicos"
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5-Decyano 5-Carboxymilrinone
CAS:Producto controlado<p>Impurity Milrinone Impurity 12<br>Applications 5-Decyano 5-Carboxymilrinone (Milrinone Impurity 12) is an impurity of Milrinone (M344680), a selective phosphodiesterase inhibitor with vasodilating and positive inotropic activity.<br>References Alousi, A.A., et al.: J. Cardiovasc Pharmacol., 5, 792 (1983); Maskin, C.S., et al.: Circulation, 67, 1065 (1983); Sinoway, L.S., et al.: J. Am. Coll. Cardiol., 2, 327 (1983); Baim, D.S., et al.: N. Engl. J. Med., 309, 748 (1983)<br></p>Fórmula:C12H10N2O3Forma y color:Off-WhitePeso molecular:230.22Epicaptopril
CAS:<p>Stability Air Sensitive<br>Applications Epicaptopril is an impurity of Captopril (C175750) which is an orally active angiotensin-converting enzyme (ACE) inhibitor used in the treatment of hypertension and congestive heart failure.<br>References Rubin, B., et al.: Eur. J Pharmacol., 51, 377 (1978);<br></p>Fórmula:C9H15NO3SForma y color:White To Off-WhitePeso molecular:217.281,2-Dioleoyl-3-trimethylammonium-propane, Chloride
CAS:Producto controladoFórmula:C42H80NO4·ClForma y color:NeatPeso molecular:698.544-Hydroperoxy Cyclophosphamide-d4
CAS:Producto controlado<p>Stability Moisture Sensitive, Temperature Sensitive<br>Applications A labelled metabolite of Cyclophosphamide. Antineoplastic; bone marrow purging agent.<br>References Takamizawa, A., et al.: J. Med. Chem., 18, 376 (1975), Jones, R.J., et al.: J. Hematother., 1, 343 (1992), Biggs, D., et al.: Prog. Clin. Biol. Res., 389, 9 (1994),<br></p>Fórmula:C7H11D4Cl2N2O4PForma y color:NeatPeso molecular:297.11POPE
CAS:Producto controlado<p>Stability Light Sensitive, Moisture Sensitive<br>Applications POPE is a component of E. Coli bacteria cell membrane.<br>References Tu, Y., et al.: Nature Nanotechnology, 8, 594 (2013).<br></p>Fórmula:C39H76NO8PForma y color:NeatPeso molecular:718.0Bis(2-chloroethyl)-1,1,2,2-d4-amine Hydrochloride
CAS:Producto controlado<p>Applications Isotope labelled Bis(2-chloroethyl)amine is a cytotoxic metabolite of Cyclophosphamide; a deuterated analog of Nor-nitrogen mustard.<br>References Colvin, M., et al.: Cancer Res., 36, 1121 (1976), Ludeman, S., et al.: Drug Metab Dispos., 20, 337 (1992), Ludeman, S.M., et al.: J. Pharmaceut. Sci., 84, 393 (1995), Yu, L., et al.: Drug Metab. Dispos., 24, 1254 (1996),<br></p>Fórmula:C42H4H5Cl2N·ClHForma y color:NeatPeso molecular:182.51Deferasirox Methyl Ester
CAS:Producto controlado<p>Applications Deferasirox Methyl Ester is a derivative of Deferasirox (D228650); an orally active tridentate iron chelator.<br>References Hershko, C., et al.: Blood, 97, 1115 (2001); Galanello, R., et al.: J. Clin. Pharmacol., 43, 565 (2003); Nick, H., et al.: Curr. Med. Chem., 10, 1065 (2003)<br></p>Fórmula:C22H17N3O4Forma y color:White To BeigePeso molecular:387.39Parathion
CAS:Producto controlado<p>Stability Hygroscopic, Moisture Sensitive<br>Applications Parathion is an organophosphate insecticide used on cotton, rice and fruit trees.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Seifert, J., et al.: Environ. Toxicol. Pharmacol., 35, 200 (2013); Ciffroy, P., et al.: Environ. Toxicol. Chem., 32, 602 (2013);<br></p>Fórmula:C10H14NO5PSForma y color:YellowPeso molecular:291.26Fenthion-d6
CAS:Producto controlado<p>Applications Labelled Fenthion, an organothiophosphate insecticide. Fenthion is also a potent acaricide.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Pati, B.R. et al.: Plant Soil, 80, 215 (1984); Barros, A.T. et al.: Vet. Parasitol., 96, 243 (2001); Kyriakidis, N.V. et al.: Food Chem., 91, 241 (2005);<br></p>Fórmula:C102H6H9O3PS2Forma y color:ColourlessPeso molecular:284.36Cyclophosphamide
CAS:<p>Cyclophosphamide is an alkylating agent type of anti-tumor drug, and its main target is DNA. High-Quality, Low-Cost!</p>Fórmula:C7H15Cl2N2O2PPureza:99.42% - >99.99%Forma y color:Liquefies On Loss Of Its Water Of CrystallizationPeso molecular:261.09N-Dechloroethyl Cyclophosphamide
CAS:<p>Stability Reacts with DMSO<br>Applications A metabolite of Cyclophosphamide (C988580).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Bohnenstengel, F., et al.: Eur. J. Clin. Pharmacol., 51, 297 (1996), Busse, D., et al.: J. Clin. Oncol., 15, 188 (1997), Roy, P., et al.: Drug Metab. Dispos., 27, 655 (1999),<br></p>Fórmula:C5H12ClN2O2PForma y color:NeatPeso molecular:198.594-Ethoxy-2-isopropyl-6-methylpyrimidine
CAS:Producto controlado<p>Applications 4-Ethoxy-2-isopropyl-6-methylpyrimidine, is the product of Diazinon (D416880) decomposition, an organophosphorus pesticide.<br>References Mekhakyan, L. A., et al.: Nov. Khim. Sredstva Zashch. , 62 (1979); Sovocool, G. W., et al.: J. Anal. Toxic., 5, 73 (1981);<br></p>Fórmula:C10H16N2OForma y color:NeatPeso molecular:180.25Terbufos-sulfoxide
CAS:Producto controlado<p>Applications Terbufos-sulfoxide was identified in vegetables and fruit by gas chromotography.<br>References Zhang, Q., et al.: Shandong Huagong, 45, 57 (2016)<br></p>Fórmula:C9H21O3PS3Forma y color:NeatPeso molecular:304.433-Acetylthio-2-methylpropionic Acid
CAS:Producto controlado<p>Impurity Captopril EP Impurity G<br>Applications 3-Acetylthio-2-methylpropionic Acid (Captopril EP Impurity G) is a key intermediate for Captopril (C175750) and other hypertension drugs.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Cushman, D., et al.: Biochem., 16, 5484 (1977), Ondetti, M., et al.: J. Med. Chem., 24, 355 (1981), Tseng, T., et al.: Cancer Lett., 62, 233 (1992),<br></p>Fórmula:C6H10O3SForma y color:NeatPeso molecular:162.21Deferasirox Ethyl Ester
CAS:Producto controlado<p>Applications Deferasirox Ethyl Ester is a derivative of Deferasirox (D228650); an orally active tridentate iron chelator.<br>References Hershko, C., et al.: Blood, 97, 1115 (2001); Galanello, R., et al.: J. Clin. Pharmacol., 43, 565 (2003); Nick, H., et al.: Curr. Med. Chem., 10, 1065 (2003)<br></p>Fórmula:C23H19N3O4Forma y color:White To Light YellowPeso molecular:401.41(R,S)-4-Hydroxy Cyclophosphamide-d4 Preparation Kit
CAS:Producto controladoFórmula:C7H11D4Cl2N2O3PForma y color:White To Off-WhitePeso molecular:281.11Cyclophosphamide Monohydrate
CAS:Producto controlado<p>Applications It is a cytotoxic nitrogen mustard derivative widely used in cancer chemotherapy. It cross-links DNA, causes strand breakage, and induces mutations. Its clinical activity is associated with a decrease in aldehyde dehydrogenase 1 (ALDH1) activity. This substance is listed as a known human carcinogen.This compound is suitable for aldehyde dehydrogenase (ALDH) related research.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Wheeler, A.G., et al.: Toxicol. Appl. Pharmacol., 4, 324 (1962), Fraiser, L.H., et al.: Drugs, 42, 781 (1991), Colvin, O.M., et al.: Curr. Pharmaceut. Design, 5, 555 (1999),<br></p>Fórmula:C7H15Cl2N2O2P·H2OForma y color:NeatPeso molecular:279.10(S)-(-)-3-Acetylthio-2-methylpropionic Acid
CAS:Producto controlado<p>Applications S-Acetylthio-2-methylpropionic Acid (S-AMPA) is a key chiral intermediate for Captopril (C175750) and other hypertension drugs.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Cushman, D., et al.: Biochem., 16, 5484 (1977), Ondetti, M., et al.: J. Med. Chem., 24, 355 (1981), Tseng, T., et al.: Cancer Lett., 62, 233 (1992),<br></p>Fórmula:C6H10O3SForma y color:ColourlessPeso molecular:162.21Fenthion Sulfoxide
CAS:Producto controlado<p>Applications Fenthion Sulfoxide is the sulfoxide anlogue and metabolite of the organothiophosphate insecticide Fenthion (F278000).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Wallnoefer, P. et al.: Pflanzensch.-Nach., 29, 236 (1976); Minelli, E.V. et al.: J. Agric. Food. Chem., 44, 936 (1996);<br></p>Fórmula:C10H15O4PS2Forma y color:NeatPeso molecular:294.33D-Captopril
CAS:Producto controlado<p>Applications D-Captopril and Captopril analogues are New Delhi metallo-β-lactamase-1 (NDM-1) inhibitors which are used clinically as antidotes for metal poisoning and bacterial infection.<br>References Ningning; X., et al.: Bioorg. Med. Chem. Lett., 24, 386 (2014); Guo, Y., et al.: Protein Cell, 2, 384 (2011)<br></p>Fórmula:C9H15NO3SForma y color:NeatPeso molecular:217.285Glufosinate Ammonium
CAS:<p>Stability Hygroscopic<br>Applications Used as a herbicide.<br>References Abbas, H., et al.: J. Agric. Food Chem., 50, 5246<br></p>Fórmula:C5H11NO4P·H4NForma y color:White To BeigePeso molecular:198.163-(2-Chloroethyl)octahydro-2-hydroxy-1,3,6,2-oxadiazaphosphonine 2-Oxide
CAS:Producto controlado<p>Impurity Cyclophosphamide Impurity B<br>Stability Hygroscopic<br>Applications A metabolite of Cyclophosphamide (C988580). Cyclophosphamide Impurity B<br>References Joqueviel, C. et al.: Drug Metab. Dispos., 26, 418 (1998);<br></p>Fórmula:C7H16ClN2O3PForma y color:NeatPeso molecular:242.64N-Acetyl Glufosinate Sodium
CAS:Producto controlado<p>Stability Very Hygroscopic<br>Applications The major metabolite of herbicidal Glufosinate (G596950).<br></p>Fórmula:C7H12NNa2O5PForma y color:White To Off-WhitePeso molecular:267.13Amifostine Trihydrate
CAS:Producto controlado<p>Applications Amifostine Trihydrate is a widely used cytoprotective and radio-protective agent.<br>References Adibhatla K.S., et al. Novel method of manufacture of high purity Amifostine trihydrate. Indian Pat. Appl. IN 2005CH01592 A 20080125. Jan 25, 2008<br></p>Fórmula:C5H15N2O3PS·3H2OForma y color:NeatPeso molecular:268.273-(Methylnitrosamino)propionitrile
CAS:Producto controlado<p>Applications 3-(Methylnitrosamino)propionitrile (MNPN) was detected for the 1st time in the saliva of betel quid chewers and is a potent carcinogen.<br>References Bartsch, H., et al.: Mutat. Res., 250, 103 (1991), Su, T., et al.: Drug Metab. Dispos., 24, 884 (1996), Guengerich, F., et al.: Chem. Res. Toxicol., 14, 611 (2001),<br></p>Fórmula:C4H7N3OForma y color:Light YellowPeso molecular:113.12Triethyl Phosphonoacetate
CAS:Producto controlado<p>Applications Reagent used for Horner-Emmons modification.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Hediger, M., et al.: Bioorg. Med. Chem., 12, 4995 (2004), Kim, J., et al.: Nat., 452, 239 (2008),<br></p>Fórmula:C8H17O5PForma y color:ColourlessPeso molecular:224.194-Hydroperoxy Cyclophosphamide
CAS:Producto controladoFórmula:C7H15Cl2N2O4PForma y color:NeatPeso molecular:293.08Triisopropyl Phosphate
CAS:Producto controlado<p>Applications Triisopropyl Phosphate can be used as a flame retardant and catalyst.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Zhang, Tie-jiang.: Meitan Jishu,29(2), 204-206 (2010);Chen, Yong-Fu, et al.: Jingxi Huagong, 17(9), 541-543 (2000)<br></p>Fórmula:C9H21O4PForma y color:NeatPeso molecular:224.23Risedronic Acid-d4 (Major)
CAS:Producto controladoFórmula:C7H7D4NO7P2Forma y color:NeatPeso molecular:287.14Deferasirox Ferrate(III) Tripotassium Complex Methanoate Hydrate
CAS:<p>Applications A metal complex of Deferasirox (D228650) as oxidation catalysts. Coordination compound.<br>References Rouan, M., et al.: Biomed. Sci. Applic., 755, 203 (2001)<br></p>Fórmula:C44H36FeK3N6O12Forma y color:NeatPeso molecular:1013.93Malathion-d6
CAS:Producto controlado<p>Applications Used as an insecticide.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>Fórmula:C102H6H13O6PS2Forma y color:NeatPeso molecular:336.40N-Nitroso Bis(2-chloroethyl)amine
CAS:<p>Applications N-Nitroso bis(2-chloroethyl)amine is a nitroamine compound that has carcinogenic effects.<br>References Luan, F. et al.: Che. Res. in Tox., 18(2), 198-203, (2005)<br></p>Fórmula:C4H8Cl2N2OForma y color:NeatPeso molecular:171.025Tris(1,3-dichloro-2-propyl) Phosphate-d15
CAS:Producto controlado<p>Applications Isotope labelled Tris(1,3-dichloro-2-propyl) Phosphate is a flame retardant present in polyurethane foams.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Stapleton, H. et al.: Env. Sci. Tech., 45, 5323 (2011);<br></p>Fórmula:C9D15Cl6O4PForma y color:Colourless To BrownPeso molecular:446.00Imidazol-1-yl-acetic Acid
CAS:Producto controlado<p>Applications An impurity arising in the synthesis of zoledronic acid (Z623500).<br></p>Fórmula:C5H6N2O2Forma y color:BeigePeso molecular:126.114-Oxo Cyclophosphamide
CAS:<p>Applications A minor metabolite of Cyclophosphamide<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Juma, F., et al.: Br. J. Clin. Pharmacol., 10, 327 (1980), Powers, J., et al.: Cancer Res., 43, 1101 (1983), Hardy, R., et al.: Ther. Drug Monit., 9, 221 (1987),<br></p>Fórmula:C7H12Cl2NO4PForma y color:NeatPeso molecular:276.05Captopril-d3
CAS:Producto controlado<p>Applications Orally active angiotensin-converting enzyme (ACE) inhibitor.<br>References Rubin, B., et al.: Eur. J Pharmacol., 51, 377 (1978),<br></p>Fórmula:C9D3H12NO3SForma y color:White SolidPeso molecular:220.30Bis(2-chloroethyl)amine Hydrochloride
CAS:Producto controlado<p>Impurity Cyclophosphamide Impurity A<br>Applications A cytotoxic metabolite of Cyclophosphamide; a deuterated analog of Nor-nitrogen mustard. Cyclophosphamide Impurity A<br>References Colvin, M. et al.: Cancer Res., 36, 1121 (1976); Ludeman, S. et al.: Drug Metab Dispos., 20, 337 (1992); Ludeman, S.M. et al.: J. Pharmaceut. Sci., 84, 393 (1995); Yu, L. et al.: Drug Metab. Dispos., 24, 1254 (1996);<br></p>Fórmula:C4H9Cl2N·ClHForma y color:White To Light YellowPeso molecular:178.49Difluoromethylenediphosphonic Acid
CAS:Producto controlado<p>Stability Hygroscopic<br>Applications A phosphonic acid derivative for development of biologically active compounds.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Ma, Q.F., et al.: Biochemistry, 29, 1412 (1990), Soti, C., et al.: Eur. J. Biochem., 270, 2421 (2003), Barabas, O., et al.: J. Biol. Chem., 279, 42907 (2004),<br></p>Fórmula:CH4F2O6P2Forma y color:NeatPeso molecular:211.98Alendronic Acid-d6 (Major)
CAS:Producto controladoFórmula:C4D6H7NO7P2Forma y color:NeatPeso molecular:255.13Metaraminol Bitartrate
CAS:Producto controlado<p>Applications Metaraminol Bitartrate is a vasopressor comparable to ephedrine used in the maintenance of arterial pressure during spinal anesthesia. Also used in the treatment of hypotension while under the effect of anaesthesia.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Ngan, K. et al.: Anesthes., 95, 307 (2001); Critchley, L. et al.: Br. J. Anaesth., 76, 734 (1996);<br></p>Fórmula:C9H13NO2·C4H6O6Forma y color:WhitePeso molecular:317.29Malathion β-Monoacid
CAS:<p>Stability Hygroscopic<br>Applications A major biodegradation product of Malathion (M111000).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Kim, Y. et al.: Chemosphere, 60, 1349 (2005); Yoshii, K. et al.: J. Health Sci., 54, 535 (2008); Hayasaka, M. et al.: Jap. J. Forensic Toxicol., 12, 15 (1994);<br></p>Fórmula:C8H15O6PS2Forma y color:NeatPeso molecular:302.30N-Nitroso Cilazapril (Ethyl-D5)
CAS:Producto controladoFórmula:C22D5H25N4O6Forma y color:NeatPeso molecular:451.528
