Péptidos y Proteínas
Los péptidos son cadenas cortas de aminoácidos unidas por enlaces peptídicos, mientras que las proteínas son cadenas más largas y complejas de aminoácidos que pueden adoptar estructuras tridimensionales funcionales. Ambos tipos de compuestos son esenciales para diversas funciones biológicas, como la catalización de reacciones (enzimas), la defensa inmunológica (anticuerpos) y la señalización celular. Las proteínas tienen una estructura jerárquica, que incluye la secuencia de aminoácidos, la estructura secundaria, terciaria y cuaternaria. Los péptidos se utilizan en terapias farmacológicas y cosméticas por sus propiedades biológicas específicas, como en el tratamiento de enfermedades metabólicas o la mejora de la regeneración celular. Las proteínas, por su parte, tienen aplicaciones en biotecnología, nutrición y medicina regenerativa.
En CymitQuimica ofrecemos péptidos y proteínas de alta pureza para investigación en biotecnología y aplicaciones terapéuticas.
Se han encontrado 3128 productos de "Péptidos y Proteínas"
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Desisobutyl-n-butyl Bortezomib
CAS:<p>Impurity Bortezomib N-Pentyl Impurity<br>Applications Desisobutyl-n-butyl Bortezomib is an impurity of Bortezomib (B675700). Bortezomib impurity 5.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Lin, G., et al.: J. Biol. Chem., 283, 34423 (2008);<br></p>Fórmula:C19H25BN4O4Forma y color:NeatPeso molecular:384.24Boceprevir (>90%)
CAS:Producto controladoFórmula:C27H45N5O5Pureza:>90%Forma y color:NeatPeso molecular:519.68Carfilzomib (2R,4S)-Diol
CAS:Producto controlado<p>Applications Carfilzomib (2R,4S)-Diol is a derivative of Carflizomib (C183460), a second-generation proteasome inhibitor that is used as a treatment in relapsed and refractory multiple myeloma.<br>References Fostier, K., et al.: Oncotargets. Therap., 5, 237 (2012); Geurink, P.P., et al.: J. Med. Chem., 56, 1262 (2013); McCormack, P.L., et al.: Drugs., 72, 2023 (2012);<br></p>Fórmula:C40H59N5O8Forma y color:NeatPeso molecular:737.93L-Valine-13C5,15N
CAS:Producto controlado<p>Applications Labelled analogue of L-Vailne. L-Valine is an essential amino acid and one of 20 proteinogenic amino acids. L-Valine cannot be manufactured by the body and must be acquired through diet or supplementation. L-valine is found in grains, dairy products, mushrooms, meats, peanuts and soy proteins. L-Valine has been used in studies to attenuate arrhythmias and induce hypotensive effects.<br>References Choi, C.W. et al.: Anim. Feed Sci. Technol., 102, 15 (2002); Kolarski, D. et al.: Krmiva, 30, 155 (1988); Oba, M. et al.: J. Dairy Sci., 93, 2044 (2010); Mitrega, K. et al.: Pharmacol. Res., 64, 218 (2011);<br></p>Fórmula:C5H1115NO2Forma y color:NeatPeso molecular:123.1Bortezomib Trimer
CAS:Producto controlado<p>Applications Bortezomib Trimer is derived from Bortezomib (B675700), which is the first proteasome inhibitor to be approved by the US FDA for multiple myeloma, a blood cancer. A reversible inhibitor of the 26S proteasome-a barrel-shaped multiprotein particle found in the nucleus and cytosol of all eukaryotic cells. Targets the ubiquitin-proteasome pathway.<br>References Nawrocki, S.T., et al: Cancer Research, 65, 11510 (2005); Drahl C.: Chem. and Eng. News, 87, 41 (2009)<br></p>Fórmula:C57H69B3N12O9Forma y color:NeatPeso molecular:1098.666Sacubitril-d4
CAS:Producto controlado<p>Applications Isotope labelled Sacubitril is an antihypertensive drug used in combination with Valsartan (V095750). The combination drug, valsartan/sacubitril, known during trials as LCZ696 and marketed under the brand name, Entresto, is a treatment for heart failure.<br>References McMurray, J., et al.: N. Eng. J. Med., 371 (2014);<br></p>Fórmula:C242H4H25NO5Forma y color:Light YellowPeso molecular:415.52(2S,4R)-Sacubitril
CAS:Producto controlado<p>Stability Temperature Sensitive<br>Applications (2S,4R)-Sacubitril is the enantiomer and an impurity of Sacubitril (S080895) which is an antihypertensive drug used in combination with valsartan.<br>References McMurray, J., et al.: N. Eng. J. Med., 371 (2014);<br></p>Fórmula:C24H29NO5Forma y color:Colourless To Off-WhitePeso molecular:411.49Cyclosporin AM 1 (>80%)
CAS:Producto controlado<p>Applications A cyclosporine metabolite specifically inhibits growth of renal cells in culture.<br>References Schultz, J.C.; et al.: Biochem. Pharma., 42, 1403 (1991), Johnson, B., et al.: Drug Metab. Dispos., 34, 556 (2006), Westley, I.S., Drug Metab. Dispos., 36, 46 (2008).<br></p>Fórmula:C62H111N11O13Pureza:>80%Forma y color:NeatPeso molecular:1218.613,3’,5-Triiodo-L-thyronine
CAS:Producto controladoFórmula:C15H12I3NO4Forma y color:White To Off-WhitePeso molecular:650.973,5,3',5'-Tetraiodo Thyroacetamide
CAS:Producto controlado<p>Impurity Levothyroxine Acetamide Impurity<br>Applications 3,5,3',5'-Tetraiodo Thyroacetamide is a thyroid hormone analogue, a Thyroxine (T425600) impurity.<br>References Andre, M., et al.: J. Chromatogr., 741, 146 (1996),<br></p>Fórmula:C14H9I4NO3Forma y color:Light Orange Colour To Light BrownPeso molecular:746.84N2-(S)-1-Carboxy-3-phenylpropyl-L-lysine
CAS:Producto controlado<p>Stability Hygroscopic<br>Applications Lisinopryl impurity.<br>References Goa, K.L., et al.: Drugs, 52, 564 (1996), Cao, X.J., et al.: J. Pharm. Biomed. Anal., 39, 39 (2005),<br></p>Fórmula:C16H24N2O4Forma y color:White To Light BeigePeso molecular:308.37N-Pyrazinylcarbonyl-L-phenylalanine Methyl Ester
CAS:<p>Applications Used for the synthesis of Bortezomib from L-phenylalanine via dipeptidyl boronic acid ester intermediates.<br>References Zhu, Y., et al.: J. Med. Chem., 52, 4192 (2009),<br></p>Fórmula:C15H15N3O3Forma y color:NeatPeso molecular:285.30Lisinopril (S,S,R)-Diketopiperazine (~90%)
CAS:<p>Impurity Lisinopril EP Impurity D<br>Stability Hygroscopic<br>Applications Lisinopril (S,S,R)-Diketopiperazine (Lisinopril EP Impurity D) is an impurity of Lisinopril (L468985), an orally active angiotensin-converting enzyme (ACE) inhibitor (1).<br>References 1. Goa, K. et al.: Drugs. 1996 Oct;52(4):564-88.<br></p>Fórmula:C21H29N3O4Pureza:~90%Forma y color:White To Off-WhitePeso molecular:387.47β-Hydroxy Thyroxine (>90%)
CAS:Producto controlado<p>Impurity Levothyroxine beta-Hydroxy Impurity / Levothyroxine beta-Hydroxy T4 Impurity<br>Applications It has been prepared for testing as possible antithyroid. It showed some thyromimetic activity.<br>References Wawzone, S., et al.: J. Med. Chem., 6, 442 (1963),<br></p>Fórmula:C15H11I4NO5Pureza:>90%Forma y color:NeatPeso molecular:792.87N-[(1S)-2-[(3-Methylbutyl)amino]-2-oxo-1-(phenylmethyl)ethyl]-2-pyrazinecarboxamide
CAS:Producto controladoFórmula:C19H24N4O2Forma y color:White To Off-WhitePeso molecular:340.4195L-Methionine [R,S]-Sulfoximine
CAS:Producto controlado<p>Applications Methionine sulfoximine inhibits both glutamine synthetase and g-glutamylcysteine synthetase. Working concentrations for inhibition of g-glutamylcysteine synthetase are 0.2-2.0 mM (52% inhibition occured at 100 mM).Methionine sulfoximine is also a toxic byproduct of nitrogen trichloride, a compound that was used to bleach unprocessed wheat flour prior to 1968. The compound has been investigated as a potential neurotoxin linked to diseases such as amyotrophic lateral sclerosis (ALS) and Parkinson’s disease.<br>References Griffith, O.W., and Meister, A.: J. Biol. Chem. 254, 7558 (1979), Willard-Mack, C.L., et al: Neuroscience, 71, 2, 589 (1996)<br></p>Fórmula:C5H12N2O3SForma y color:NeatPeso molecular:180.23N-Pyrazinylcarbonyl-L-phenylalanine
CAS:Producto controlado<p>Applications Used for the synthesis of Bortezomib (B675700) from L-phenylalanine via dipeptidyl boronic acid ester intermediates.<br>References Zhu, Y., et al.: J. Med. Chem., 52, 4192 (2009),<br></p>Fórmula:C14H13N3O3Forma y color:WhitePeso molecular:271.271-Nitrosopyrrolidine-2-carboxylic Acid
CAS:Producto controlado<p>Applications 1-nitrosopyrrolidine-2-carboxylic acid (cas# 2571-28-0) is a useful research chemical.<br></p>Fórmula:C5H8N2O3Forma y color:NeatPeso molecular:144.129[Des-Thr-ol8]-[D-Cys7]-Octreotide TFA
CAS:Producto controladoFórmula:C45H57N9O9S2•x(C2HF3O2)Forma y color:NeatPeso molecular:932.1211402
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