Radicales libres y agentes oxidantes/reductores
Los radicales libres son moléculas con electrones desapareados que pueden dañar estructuras celulares, afectando la estabilidad de los ingredientes activos farmacéuticos (API). Estos radicales son importantes en la formulación de APIs, ya que su presencia puede influir en la estabilidad y eficacia del fármaco. Los agentes oxidantes son sustancias que facilitan la pérdida de electrones, lo que puede ser útil en la fabricación de ciertos APIs, pero también pueden generar reacciones indeseadas si no se controlan adecuadamente. Los agentes reductores, por otro lado, pueden estabilizar algunos compuestos activos al evitar la oxidación. El control de radicales libres y la manipulación de agentes oxidantes y reductores son esenciales en el desarrollo de APIs con una vida útil prolongada y una actividad terapéutica eficiente.
Se han encontrado 23 productos para "Radicales libres y agentes oxidantes/reductores ".
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Edaravone
CAS:Edaravone (MCI-186)(MCI-186) is a potent new free radical scavenger used for the therapy of patients with acute brain infarction.Fórmula:C10H10N2OPureza:99.44% - >99.99%Forma y color:Yellow SolidPeso molecular:174.1992Antitrypanosomal agent 1
CAS:Potent TR inhibitor with IC50: 3.3μM, also inhibits glutathione reductase (IC50: 64.8μM) and T. brucei (EC50: 1μM).Fórmula:C11H14Cl3NOPureza:97.76%Forma y color:SolidPeso molecular:282.59Glutathione oxidized
CAS:Glutathione oxidized (L(-) -glutathione) is the oxidized form of Glutathione, which is a major antioxidant and antidote in cells. High-Quality, Low-Cost!Fórmula:C20H32N6O12S2Pureza:97.27% - 99.96%Forma y color:White SolidPeso molecular:612.631L-Glutathione reduced
CAS:L-Glutathione reduced (Glutathione) is a naturally occurring tripeptide found in cells as an endogenous antioxidant that scavenges oxygen free radicals.Fórmula:C10H17N3O6SPureza:97.37% - 99.99%Forma y color:White SolidPeso molecular:307.323Ascorbyl palmitate
CAS:Ascorbyl palmitate (L-Ascorbic acid 6-hexadecanoate), an ester formed from ascorbic acid and palmitic acid, produces a fat-soluble form of vitamin C.Fórmula:C22H38O7Pureza:99.52%Forma y color:SolidPeso molecular:414.53Ebselen
CAS:Ebselen is a selenium compound with anti-inflammatory and antioxidant properties, mimicking glutathione peroxidase to protect against ROS damage.Fórmula:C13H9NOSePureza:98.99% - 99.94%Forma y color:White SolidPeso molecular:274.18L-Ascorbic acid
CAS:L-Ascorbic acid (Vitamin C) is a natural product that is a potent reducing agent and antioxidant.Fórmula:C6H8O6Pureza:99.89% - 99.89%Forma y color:White SolidPeso molecular:176.1241L-SelenoMethionine
CAS:L-Selenomethionine is a natural amino acid boosting cell growth and antioxidant enzyme levels.Fórmula:C5H11NO2SePureza:98% - 99.67%Forma y color:White To Off-WhitepowderPeso molecular:196.11Ferroptosis Compound Library
A collection of xnum natural product molecules originated from Tibetan medicine, which can be used for high-throughput and high-content screening.Forma y color:Odour SolidL-Dehydro Ascorbic Acid (>90%)
CAS:Producto controladoApplications The reversibly oxidized form of ascorbic acid.
References Moubasher, et al.: J. Biol. Chem., 176, 633 (1948), Sy, K., et al.: J. Food Prot., 68, 1176 (2005), Llorach, R., et al.: Food Chem., 2008, 108, 1028 (2008),Fórmula:C6H6O6Pureza:>90%Forma y color:NeatPeso molecular:174.11JKE-1674
CAS:JKE-1674 is an orally active glutathione peroxidase 4 (GPX4) inhibitor and the active metabolite of ML-210.Cost-effective and quality-assured.Fórmula:C20H20Cl2N4O4Pureza:98.02% - 99.72%Forma y color:White SolidPeso molecular:451.303Diethylmaleate
CAS:Diethylmaleate (Maleic acid, diethyl ester) is the diethyl ester of maleic acid and a glutathione-depleting compound that inhibits NF-kB.Fórmula:C8H12O4Pureza:98%Forma y color:Transparent LiquidPeso molecular:172.18Nitecapone
CAS:Nitecapone is a reversible inhibitor of S-COMT (IC50 values of 300 nM in rat liver)Fórmula:C12H11NO6Pureza:98.39%Forma y color:SolidPeso molecular:265.2188S-(4-Hydroxybenzyl)glutathione
CAS:L-γ-Glutamyl-S-[(4-hydroxyphenyl)methyl] from Gastrodia elata inhibits kainic acid binding to brain receptors.Fórmula:C17H23N3O7SPureza:99.78% - 99.88%Forma y color:White SolidPeso molecular:413.445ML-210
CAS:ML-210 (CID 49766530) is a glutathione peroxidase 4 (GPX4) inhibitor. ML-210 has antitumor activity and induces ferroptosis. Cost-effective and quality-assured.Fórmula:C22H20Cl2N4O4Pureza:97% - 99.03%Forma y color:SolidPeso molecular:475.325L-Theanine
CAS:L-Theanine, a unique amino acid from Camellia sinensis tea, induces relaxation without drowsiness.Fórmula:C7H14N2O3Pureza:99.31% - 99.38%Forma y color:SolidPeso molecular:174.1977Acifluorfen
CAS:Producto controladoAcifluorfen: PROTOX inhibitor herbicide causing photooxidative damage in plants; may induce liver tumors in rodents.Fórmula:C14H7ClF3NO5Pureza:99.60%Forma y color:SolidPeso molecular:361.657N-Acetyl-D-cysteine
CAS:N-Acetyl-D-cysteine has antioxidant activities and scavenges ROS through the reaction with its thiol group.Fórmula:C5H9NO3SPureza:97.12% - 99.71%Forma y color:SolidPeso molecular:163.195Tempol
CAS:Tempol (Tanol) is a superoxide scavenger. It has anti-inflammatory, neuroprotective and analgesic effects.Fórmula:C9H18NO2Pureza:97% - 99.98%Forma y color:Yellow SolidPeso molecular:172.25TRi-1
CAS:TRi-1 irreversibly inhibits TXNRD1 (IC50: 12 nM) with low mitochondrial toxicity for cancer treatment.Fórmula:C12H9ClN2O5SPureza:97.14%Forma y color:SolidPeso molecular:328.728
