Sales y derivados de API
Las sales de los Ingredientes Farmacéuticos Activos (API) son compuestos formados por la reacción de un ácido con una base, resultando en un equilibrio iónico. Estas sales suelen mejorar la solubilidad y estabilidad de los APIs, facilitando su absorción en el cuerpo. Los derivados de API son variantes químicas de un principio activo que pueden tener propiedades mejoradas o modificadas para optimizar su eficacia terapéutica. Las sales de APIs se utilizan en la formulación de medicamentos orales, inyectables y tópicos. Además, los derivados de APIs pueden mejorar la farmacocinética de los fármacos, como la liberación controlada de activos.
En CymitQuimica contamos con sales y derivados de APIs con la pureza y calidad necesarias para investigación y desarrollo de formulaciones farmacéuticas.
Se han encontrado 79468 productos de "Sales y derivados de API"
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2,2'-(Thiobis(2-hydroxy-5,1-phenylene))bis(4H-benzo[e][1,3]oxazin-4-one)
CAS:<p>Please enquire for more information about 2,2'-(Thiobis(2-hydroxy-5,1-phenylene))bis(4H-benzo[e][1,3]oxazin-4-one) including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>Fórmula:C28H16N2O6SPureza:Min. 95%Peso molecular:508.5 g/mol13-O-Desmethyl tacrolimus
CAS:<p>Tacrolimus is a macrolide immunosuppressant that is used to prevent organ rejection in transplant patients. It binds to the cytosolic protein, FKBP-12, which prevents calcineurin from dephosphorylating and activating nuclear factor of activated T cells (NFAT). Tacrolimus inhibits the production of IL-2 and other cytokines by T cells, suppressing proliferation. Tacrolimus has been shown to be bioequivalent when administered orally or intravenously. Bioavailability may be increased when taken with food.</p>Fórmula:C43H67NO12Pureza:90%MinForma y color:PowderPeso molecular:789.99 g/molTamitinol
CAS:<p>Tamitinol is a neurotropic drug. It has been found to help symptoms of obsessive rumination in conjunction with maprotiline.</p>Fórmula:C12H20N2OSPureza:98%Forma y color:SolidPeso molecular:240.37Antidepressant agent 8
CAS:<p>Antidepressant agent 8 (Compound 1f) acts as a selective antagonist for the NMDA receptor GluN1/2A (NMDA receptorGluN1/2A), with an IC50 of 2.94 μmol/L. In a hydrocortisone-induced zebrafish depression model, it demonstrates antidepressant-like effects and shows good blood-brain barrier penetration.</p>Fórmula:C18H23FN4OS2Forma y color:SolidPeso molecular:394.53Perfluoroheptanesulfonic acid
CAS:<p>Perfluoroheptanesulfonic acid (1-Perfluoroheptanesulfonic acid; Perfluoroheptanesulphonic acid) is a perfluoroalkyl substance (PFAS). This compound has been detected in landfill leachate and has been shown to induce deformities in zebrafish larvae (EC50=168.1 μM). Exposure to PFHpS in fetuses can lead to reduced birth weight.</p>Fórmula:C7HF15O3SForma y color:SolidPeso molecular:450.12LY 215490
CAS:<p>LY 215490 is a selective AMPA receptor antagonist with neuroprotective properties in rat ischemia.</p>Fórmula:C13H21N5O2Pureza:98%Forma y color:SolidPeso molecular:279.34Onfasprodil
CAS:<p>Onfasprodil, NR2B inhibitor & GABA regulator, potential for Alzheimer's research. (Patent CN111481543A)</p>Fórmula:C20H23FN2O3Forma y color:SolidPeso molecular:358.413-Methoxy PCE hydrochloride
CAS:<p>3-Methoxy PCE (3-MEO PCE) hydrochloride is an arylcyclohexylamine compound that functions as an NMDA receptor antagonist with a pKi value of 7.22.</p>Fórmula:C15H24ClNOForma y color:SolidPeso molecular:269.81(3S,6R)-NML
CAS:<p>(3S,6R)-NML is an NMDA receptor antagonist with pIC50 values of 4.8 [GluN1-GluN2A], 4.6 [GluN1-GluN2B], 5.0 [GluN1-GluN2C], and 5.0 [GluN1-GluN2D]. It is applicable in the study of depression.</p>Fórmula:C20H27NOForma y color:SolidPeso molecular:297.435Caramboxin
CAS:<p>Caramboxin, a neurotoxin, can induce acute kidney injury.</p>Fórmula:C11H13NO6Forma y color:SolidPeso molecular:255.22PDE2 inhibitor 6
CAS:<p>PDE2 inhibitor6 (Compound 1) is an orally active phosphodiesterase (PDE) inhibitor, effectively inhibiting PDE2A, PDE3B, and PDE10A2 with IC50 values of 0.95 nM, 6.17 μM (pIC50=5.21), and 87.1 nM (pIC50=7.06), respectively. It modulates AMPA receptor activity, enhances synaptic plasticity, and improves learning and memory in rat models. Furthermore, PDE2 inhibitor6 possesses blood-brain barrier permeability.</p>Fórmula:C20H22F2N6OForma y color:SolidPeso molecular:400.425NMDA receptor antagonist-3
<p>NMDA antagonist-3: recovery rate 40% at 100 μM, low toxicity in SH-SY5Y, human stem cells.</p>Fórmula:C13H19N3O6Forma y color:SolidPeso molecular:313.31PF-06462894
CAS:PF-06462894: morpholinopyrimidone, mGlu5 antagonist (Ki=6nM), no immune activation in mouse model.Fórmula:C18H23N3O3Pureza:98%Forma y color:SolidPeso molecular:329.39(RS)-AMPA hydrochloride
CAS:<p>(RS)-AMPA ((±)-AMPA) hydrochloride is a glutamate analog and serves as an efficient selective agonist for the excitatory neurotransmitter L-glutamic acid (L-glutamic acid). It does not interfere with the binding sites of alginate or NMDA receptors.</p>Fórmula:C7H11ClN2O4Forma y color:SolidPeso molecular:222.63Metaphit methylsulfate
CAS:<p>Metaphit methylsulfate is a specific PCP antagonist and an acylating agent for the [3H] phencyclidine binding site in rat brain homogenate. It inhibits PCP-induced motor activity through a presynaptic mechanism.</p>Fórmula:C19H28N2O3S2Forma y color:SolidPeso molecular:396.567Caged MK801
CAS:Caged MK801 (cMK801) is a selective, noncompetitive, and irreversible blocker of the NMDA receptor open channel. The NVOC cage is compatible in neuropharmacology and does not alter the intrinsic activity of the molecule.Fórmula:C26H24N2O6Forma y color:SolidPeso molecular:460.48YY-23
CAS:<p>YY-23 is a selective NMDAR (containing GluN2C or GluN2D) inhibitor. By inhibiting NMDARs with GluN2D on GABAergic interneurons in the prefrontal cortex, YY-23 suppresses GABAergic neurotransmission and enhances excitatory transmission. YY-23 exhibits antidepressant activity and is useful for neurological disease research.</p>Fórmula:C33H54O8Forma y color:SolidPeso molecular:578.777Macitentan (n-butyl analogue)
CAS:<p>Macitentan n-butyl analogue, an oral ETA/ETB receptor blocker, may treat IPF and PAH.</p>Fórmula:C20H21Br2N5O4SPureza:98%Forma y color:SolidPeso molecular:587.29Antidepressant agent 9
CAS:<p>Antidepressant agent 9 (Compound 24) is an orally active inhibitor of NMDAR and SERT, with IC50 values of 3.50 μM and 1044 nM, respectively. It exhibits good metabolic stability and plasma exposure, and demonstrates antidepressant-like effects in the forced swim test in mice.</p>Fórmula:C17H24N2Forma y color:SolidPeso molecular:256.386DL-AP5 lithium
CAS:<p>DL-AP5 (2-APV) lithium is a competitive antagonist of the NMDA (N-Methyl-D-aspartate) receptor. It exhibits notable analgesic activity and specifically blocks channels in the rabbit retina.</p>Fórmula:C5H11LiNO5PForma y color:SolidPeso molecular:203.06Lu AF90103
CAS:<p>Lu AF90103 (Compound 42e) is the methyl ester prodrug of compound 42d, capable of crossing the blood-brain barrier. Compound 42d acts as a partial agonist of the GluN1/GluN2B complex, with an efficacy of 24% and an EC50 value of 78 nM. Lu AF90103 plays a significant role in neuropsychiatric disorder research.</p>Fórmula:C13H15N3O3SForma y color:SolidPeso molecular:293.342LY 235959
CAS:<p>LY 235959 is a NMDA receptor antagonist.</p>Fórmula:C11H20NO5PPureza:98%Forma y color:SolidPeso molecular:277.25EU 1622-240
CAS:<p>EU 1622-240 is an allosteric modulator with a preference for GluN2B, GluN2C, and GluN2D, exhibiting EC50 values of 0.57, 0.82, and 1.1 μM, respectively. It possesses favorable physicochemical properties, along with in vitro stability and permeability.</p>Fórmula:C20H14BrF2N3O2SForma y color:SolidPeso molecular:478.31BMS-986163
CAS:<p>BMS-986163, a prodrug, quickly becomes BMS-986169, a GluN2B inhibitor (Ki=4 nM, IC50=24 nM).</p>Fórmula:C23H28FN2O5PPureza:98%Forma y color:SolidPeso molecular:462.45(RS)-AMPA
CAS:<p>(RS)-AMPA ((±)-AMPA) is a glutamate analog. (RS)-AMPA is an agonist of effective and selective excitatory neurotransmitter L-glutamic acid.</p>Fórmula:C7H10N2O4Pureza:98%Forma y color:SolidPeso molecular:186.17EMD-95885
CAS:<p>EMD-95885 is a selective antagonist of NMDA receptors containing NR2B subunits, with an IC50 of 3.9 nM. It does not interact with other sites on the NMDA receptor.</p>Fórmula:C22H23FN2O3Forma y color:SolidPeso molecular:382.428NMDA agonist 1
CAS:<p>NMDA agonist 1 (compound 42d) is a potent NMDA agonist with a Ki value of 96 nM. It acts as a partial agonist of the GluN1/GluN2B complex, exhibiting an EC50 value of 78 nM.</p>Fórmula:C12H13N3O3SForma y color:SolidPeso molecular:279.315NYX-2925
CAS:<p>NYX-2925, an oral NMDAR modulator, enhances Src in mPFC. No CAMKII impact or addictive/sedative effects. Useful for CNS disorder studies.</p>Fórmula:C14H23N3O4Forma y color:SolidPeso molecular:297.35LY3130481
CAS:LY3130481: TARP γ-8 dependent AMPA receptor blocker; selectively targets AMPA/TARP γ-8 with 65 nM IC50.Fórmula:C19H18N4O3SForma y color:SolidPeso molecular:382.44LY503430
CAS:<p>LY503430: Oral AMPA enhancer with nootropic, neuroprotective properties, mitigates 6-OHDA/MPTP brain damage.</p>Fórmula:C20H25FN2O3SPureza:98%Forma y color:SolidPeso molecular:392.49Blixeprodil
CAS:<p>Blixeprodil (GM-1020) is an orally active NMDA receptor antagonist with an affinity of Ki = 3.25 µM in rat cortical tissue. It inhibits NR1/2A-NMDAR-mediated currents in HEK293 cells with an IC50 of 1.192 µM. Blixeprodil demonstrates antidepressant effects in rat models and exhibits blood-brain barrier permeability.</p>Fórmula:C13H16FNOForma y color:SolidPeso molecular:221.271(RS)-AMPA monohydrate
CAS:<p>(RS)-AMPA monohydrate, potent glutamate analogue, selectively activates L-glutamic acid without affecting kainic acid or NMDA receptors.</p>Fórmula:C7H12N2O5Forma y color:SolidPeso molecular:204.182(RS)-AMPA hydrobromide
CAS:AMPAR agonistFórmula:C7H11BrN2O4Pureza:98%Forma y color:SolidPeso molecular:267.08SDZ 220-040
CAS:<p>SDZ 220-040 是一种选择性哺乳动物 NMDA 受体拮抗剂，可诱导根系生长的部分无重力模式 。</p>Fórmula:C16H16Cl2NO6PPureza:98.13%Forma y color:SolidPeso molecular:420.18BDZ-g
CAS:BDZ-g: potent, selective AMPA receptor antagonist; useful for researching neurological disorders.Fórmula:C21H21N5O2SPureza:99.97%Forma y color:SolidPeso molecular:407.49(1E,4E)-1,5-Bis[3,5-bis(methoxymethoxy)phenyl]-1,4-pentadiene-3-one
CAS:Fórmula:C25H30O9Pureza:>97.0%(HPLC)Forma y color:White to Yellow to Green powder to crystalPeso molecular:474.51D-2-Phenylglycine
CAS:Fórmula:C8H9NO2Pureza:>99.0%(T)Forma y color:White to Almost white powder to crystalPeso molecular:151.17Veratramine
CAS:Fórmula:C27H39NO2Pureza:>98.0%(HPLC)Forma y color:White to Light yellow powder to crystalPeso molecular:409.61tert-Butyl Hydrogen Tetradecanedioate
CAS:Fórmula:C18H34O4Pureza:>95.0%(GC)(T)Forma y color:White to Light yellow powder to crystalPeso molecular:314.474-Maleimidobutyric Acid
CAS:Fórmula:C8H9NO4Pureza:>98.0%(GC)Forma y color:White to Almost white powder to crystalPeso molecular:183.164,4'-Diethynylbiphenyl
CAS:Fórmula:C16H10Pureza:>98.0%(GC)Forma y color:White to Light yellow to Light orange powder to crystalPeso molecular:202.26Isobutyryl Chloride
CAS:Fórmula:C4H7ClOPureza:>98.0%(GC)(T)Forma y color:Colorless to Light yellow clear liquidPeso molecular:106.55Ref: ST-EA-CP-D73001
Producto descatalogadoBemotrizinol Impurity Mixture
Diagnostic or lab reagents on a backing, prepared diagnostic or lab reagents whether or not on a backing, whether or not in the form of kits, nesoiForma y color:Light Yellow PowderAmiodarone Related Compound C
CAS:Aromatic heterocyclic compounds with oxygen hetero-atom(s) only, nesoiFórmula:C25H30INO3Peso molecular:519.12704
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