Sulfonamidas y derivados
Las sulfonamidas son compuestos que contienen un grupo funcional sulfonamida (-SO₂NH₂), en el que un átomo de azufre está unido a un grupo amino. Fueron de los primeros antibióticos sintéticos utilizados en medicina, inhibiendo la síntesis de ácido fólico en bacterias, lo que les confiere propiedades antimicrobianas. Se utilizan principalmente para tratar infecciones bacterianas, aunque hoy en día su uso se ha visto reducido debido a la resistencia antimicrobiana. Además de su uso en antibióticos, las sulfonamidas también tienen aplicaciones en el tratamiento de enfermedades como la malaria y enfermedades inflamatorias intestinales.
En CymitQuimica ofrecemos sulfonamidas y sus derivados con alto grado de pureza para investigación en microbiología y desarrollo farmacéutico.
Se han encontrado 2592 productos de "Sulfonamidas y derivados"
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meta-Glimepiride Impurity.
CAS:Producto controladoFórmula:C24H34N4O5SForma y color:WhitePeso molecular:490.62Acetaminophen Glutathione-d3 Disodium Salt (~90%)
CAS:Producto controladoFórmula:C18H19D3N4Na2O8SPureza:~90%Forma y color:Off-White To Dark BrownPeso molecular:503.452,4'-Diaminophenyl Sulfone
CAS:Producto controladoFórmula:C12H12N2O2SForma y color:NeatPeso molecular:248.30088Niflumic Acid-d5 (Major)
CAS:Producto controlado<p>Applications Anti-inflammatory. Selective cyclooxygenase-2 (COX-2) inhibitor.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Glasson, et al.: Biochem, Pharmacol., 18, 633 (1969), Boissier, et al.: Therapie, 26, 211 (1971), Sorenson, J.R.J., et al.: J. Med. Chem., 19, 135 (1976), Barnett, J., et al.: Biochim. Biophys. Acta, 1209, 130 (1994), Johnson, J.L., et al.: Arch. Biochem. Biophys., 324, 26 (1995),<br></p>Fórmula:C13H4D5F3N2O2Forma y color:NeatPeso molecular:287.254-Amino-4'-hydroxydiphenylsulfone
CAS:<p>Stability Hygroscopic<br>Applications 4-Amino-4'-hydroxydiphenylsulfone is a diaryl sulfone with antileprotic activity. 4-Amino-4'-hydroxydiphenylsulfone is an antibacterial agent.<br>References Colwell, W.T. et al.: J. Med. Chem., 17, 142 (1974); Agrawal, V.K. et al.: Acta Microb iol. Immunol. Hung., 50, 385 (2003);<br></p>Fórmula:C12H11NO3SForma y color:Light BrownPeso molecular:249.291-Cyclohexyl-3-(p-sulfamoylphenethyl)urea
CAS:Producto controlado<p>Impurity Glipizide EP Impurity H<br>Applications 1-Cyclohexyl-3-(p-sulfamoylphenethyl)urea (Glipizide EP Impurity H) is an impurity of Glipizide (G410225).<br>References Jurca, B. et al.: J. Therm. Anal. Calor., 62, 859 (2000);<br></p>Fórmula:C15H23N3O3SForma y color:WhitePeso molecular:325.43N-(1-Phenylethyl) Ibuprofen Amide(Mixture of 4 Diastereomers)
CAS:Producto controlado<p>Applications Ibuprofen (I140000) impurity, an anti-inflammatory compound.<br>References Rubin, A., et al.: J. Pharm. Sci., 74, 82 (1985), Tracy, T., et al.: Drug Metab. Dispos., 20, 322 (1992),<br></p>Fórmula:C21H27NOForma y color:WhitePeso molecular:309.45Penoxsulam
CAS:<p>Applications Penoxsulam is an acetolactate synthase inhibitor herbicide developed for controlling grasses, sedges, and broadleaf weeds in rice culture.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Jabusch, T., and Tjeerdema, R.: J. Agric. Food Chem. 53, 18, 7179-183 (2005); Bamcjero, M., et al.: Sci. Total Environ. 807, 1, 160793 (2021)<br></p>Fórmula:C16H14F5N5O5SForma y color:White To Light BrownPeso molecular:483.37N-Acetyl Sulfadiazine-13C6
CAS:Producto controlado<p>Applications A major metabolite of Sulfadiazine.<br>References Woolley, J., et al.: Drug Metab. Dispos., 7, 94 (1979), Nielsen, P., et al.: Biochem. Pharmacol., 35, 2509 (1986), Anari, M., et al.: Anal. Chem., 76, 823 (2004), Edlund, P., et al.: J. Pharm. Biomed. Anal., 34, 1079 (2004),<br></p>Fórmula:C613C6H12N4O3SForma y color:NeatPeso molecular:298.27Acetazolamide Disulphide Impurity
CAS:<p>Impurity Acetazolamide Disulphide Impurity<br>Applications bis(2-Acetamido-1,3,4-thiadiazol-5-yl) Disulfide is an impurity of Acetazolamide (A161500), a carbonic anhydrase inhibitor. Diuretic. (Acetazolamide Disulphide Impurity)<br>References Srinivasu, P., et. al.: J. Pharmaceut. Biomed. Anal., 52, 142 (2010); Vitale, R., et al.: J. Med. Chem., 52, 5990 (2009); Bell, H., et al.: Am. J. Physiol., 297, R370 (2009); Maresca, A., et al.: Bioorg. Med. Chem. Lett., 19, 4929 (2009); Liu, Y., et al.: Anal. Bioanal. Chem., 395, 591 (2009)<br></p>Fórmula:C8H8N6O2S4Forma y color:NeatPeso molecular:348.45Bumetanide Butyl Ester
CAS:Producto controlado<p>Applications Bumetanide Butyl Ester is an intermediate in the preparation of Bumetanide<br>References Petzinger, E., et al.: Am. J. Physiol., 265, G942 (1993);<br></p>Fórmula:C21H28N2O5SForma y color:NeatPeso molecular:420.52Acetaminophen Acetate (Acetaminophen Impurity)
CAS:<p>Impurity Paracetamol EP Impurity H/ Acetaminophen impurity H<br>Applications Acetaminophen Acetate is an impurity of Acetaminophen (A161220), an analgesic and antipyretic agent used as a pain reliever to treat headache, muscle aches, and arthritis (1,2,3).<br>References (1) McGill, M. R. and Jaeschke, H. Pharm Res. 30, 2174 (2013)(2) Fairbrother, J.E., et al.: Anal. Profiles Drug Subs., 3, 1 (1974) (3) Hinson, J.A., et al.: Rev. Biochem. Toxicol., 2, 103 (1980)<br></p>Fórmula:C10H11NO3Forma y color:White To Off-WhitePeso molecular:193.20Sulfadoxine
CAS:Producto controlado<p>Applications Used as an antibacterial.<br>References Kapoor, V.K., et al.: Anal. Profiles Drug Subs., 17, 571 (1988)<br></p>Fórmula:C12H14N4O4SForma y color:WhitePeso molecular:310.33Dapsone Hydroxylamine
CAS:<p>Stability Light Sensitive, Temperature Sensitive<br>Applications A metabolite of Dapsone.<br>References Preuss, C.V., et al.: Biochem. Pharmacol., 51, 1661 (1996), F., et al.: J. Pharmacol. Exp. Ther., 323, 771 (2007), Roychowdhury, S., et al.: Drug Metab. Disposition, 35, 676 (2007), Obach, R., et al.: Environ. Mol. Mutagen., 49, 631 (2008), Veggi, L., et al.: Life Sci., 83, 155 (2008), Khan,<br></p>Fórmula:C12H12N2O3SForma y color:Off-WhitePeso molecular:264.30Azoxydapsone
CAS:Producto controlado<p>Applications Azoxydapsone is a primary urinary N-oxidation metabolite of Dapsone (D193250); an antibacterial used in the treatment of dermatitis herpetiformis.<br>References Israili, Z.H., et al.: J. Pharmacol. Exp. Ther., 187, 138 (1973); Cucinell, S.A., et al.: Am. J. Trop. Med. Hyg., 21, 322 (1972); Francis, J., et al.: Br. J. Pharmacol., 5, 565 (1950); Uetrecht, J., et al.: Clin. Dermatol., 7, 111 (1989); Reszka, K., et al.: Chem. Res. Toxicol., 22, 1137 (2009); Santos, J., et al.: Bioorg. Med. Chem., 17, 3795 (2009); Varma, M., et al.: J. Med. Chem., 52, 4844 (2009)<br></p>Fórmula:C24H20N4O5S2Forma y color:NeatPeso molecular:508.57Sulfacetamide
CAS:Producto controlado<p>Applications Sulfacetamide is an antibiotic used for the treatment of skin infections and urinary tract infections. Sulfacetamide is also used to treat acne and seborrheic dermatitis. Sulfacetamide was investigated for potential anti-inflammatory properties<br>References Wittwer, M.B., et al.: J. Med. Chem., 56, 781 (2013); Wang. X., et al.: Afr. J. Micriobiol., 6, 4533 (2012); Yu, B., et al.: Euro. J. Med. Chem., 46, 5833 (2011);<br></p>Fórmula:C8H10N2O3SForma y color:Off-WhitePeso molecular:214.24Acetaminophen-cysteine
CAS:Producto controladoFórmula:C11H14N2O3SForma y color:NeatPeso molecular:254.31Zonisamide-13C2-15N
CAS:<p>Applications Zonisamide-13C2-15N is the labeled analogue of Zonisamide (Z700000), a sulfonamide antiseizure agent; blocks repetitive firing of voltagesensitive sodium channels and reduces voltage-sensitive T-type calcium currents. Heterocyclic methanesulfonide with anticonvulsant properties. The compound is under investigation for potential therapeutic use as an antiepileptic drug. Anticonvulsant.<br>References Masuda, Y., et al.: Arzneim.-Forsch., 30, 477 (1980); Hammond, E.J., et al.: Gen. Pharmacol., 18, 303 (1987); Schmidt, D., et al.: Epilepsy Res., 15, 67 (1993); Sorkin, E.M., et al.: Drugs, 45, 760 (1993)<br></p>Fórmula:C613C2H8N15NO3SForma y color:Off-White To Light YellowPeso molecular:215.2Ibuprofen Carboxylic Acid-d3 (Mixture of Diastereomers)
CAS:Producto controlado<p>Applications The major labelled metabolite of Ibuprofen; may reduce the risk of cataract by protecting lenticular enzymes.<br>References Bhuyan, K., et al.: Life Sci., 38, 1463 (1986), Blakytny, R., et al.: Biochem. J., 288, 303 (1992),Ganea, E., et al.: Eur. J. Biochem., 231, 181 (1995), Mitchell, J., et al.: Br. J. Pharmacol., 128, 1121 (1999),<br></p>Fórmula:C13H13D3O4Forma y color:NeatPeso molecular:239.284-Chlorobenzoic Acid
CAS:Producto controlado<p>Impurity Acemetacin EP Impurity A / Bezafibrate EP Impurity B<br>Applications A benzoic acid analogue that showed antifungal activity against strains of Aspergillus flavus, Aspergillus fumigatus and Aspergillus terreus, causative agents of human aspergillosis, in in vitro bioassays. It is used as a preservative.<br>References Rep, M., et al.: J. Biol. Chem., 275, 8290 (2000), Jaeger, T., et al.: Biofactors, 27, 109 (2006), Kim, J., et al.: Fungal Biology, 114, 817 (2010),<br></p>Fórmula:C7H5ClO2Forma y color:White To Off-WhitePeso molecular:156.57
