Sulfonamidas y derivados
Las sulfonamidas son compuestos que contienen un grupo funcional sulfonamida (-SO₂NH₂), en el que un átomo de azufre está unido a un grupo amino. Fueron de los primeros antibióticos sintéticos utilizados en medicina, inhibiendo la síntesis de ácido fólico en bacterias, lo que les confiere propiedades antimicrobianas. Se utilizan principalmente para tratar infecciones bacterianas, aunque hoy en día su uso se ha visto reducido debido a la resistencia antimicrobiana. Además de su uso en antibióticos, las sulfonamidas también tienen aplicaciones en el tratamiento de enfermedades como la malaria y enfermedades inflamatorias intestinales.
En CymitQuimica ofrecemos sulfonamidas y sus derivados con alto grado de pureza para investigación en microbiología y desarrollo farmacéutico.
Se han encontrado 2592 productos de "Sulfonamidas y derivados"
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rac-Ibuprofen Amide
CAS:Producto controlado<p>Impurity Ibuprofen EP Impurity C<br>Applications An impurity of Ibuprofen (I140000).<br>References Haikala, V., et al.: J. Pharm. Sci., 80, 456 (1991), Sochor, J., et al.: J. Pharm. Biomed. Anal., 13, 899 (1995),<br></p>Fórmula:C13H19NOForma y color:WhitePeso molecular:205.30ortho Gliclazide
CAS:<p>Applications Impurity of Gliclazide (G409875).<br>References Hisashi, M., et al.: Eur. J. Drug Metab. Pharmacokinet., 8, 117 (1983),<br></p>Fórmula:C15H21N3O3SForma y color:WhitePeso molecular:323.41Sulfadoxine-d4
CAS:Producto controlado<p>Applications Labelled Sulfadoxine (S699070). Used as an antibacterial.<br>References Kapoor, V.K., et al.: Anal. Profiles Drug Subs., 17, 571 (1988)<br></p>Fórmula:C12D4H10N4O4SForma y color:NeatPeso molecular:314.354',6'-Dinitro-2'-phenoxymethanesulfonanilide
CAS:<p>Impurity Nimesulide EP Impurity A<br>Applications 4',6'-Dinitro-2'-phenoxymethanesulfonanilide, is an impurity of the drug Nimesulide (N477500), which is an antiinflammatory agent. Preferentially inhibits COX-2 over COX-1. Suppresses chemical-induced carcinogenesis in mice and rats. Inhibits LPS-induced TNF-alpha production.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Pairet, M., et al.: Inflamm. Res., 47, S93 (1998), Fukutake, M., et al.: Carcinogenesis, 19, 1939 (1998), Okajima., E., et al.: Cancer Res., 58, 3028 (1998), Azab, A., et al.: Life Sci., 63, 323 (1998)<br></p>Fórmula:C13H11N3O7SForma y color:NeatPeso molecular:353.31rac α-Hydroxy Ibuprofen
CAS:Producto controlado<p>Impurity Ibuprofen EP Impurity M<br>Applications A potential precursor of Ibuprofen and Naproxen. Antiinflammatory agent.<br>References Williams, K., et al.: Pharm. Ther., 46, 273 (1990), Evans, A., et al.: Eur. J. Clin. Pharmacol., 42, 237 (1992), Tucker, G., et al.: Lancet, 355, 1085 (2000), Tan, S., et al.: Xenobiotica, 32, 683 (2002), Fura, A., et al.: J. Pharm. Biomed. Anal., 32, 513 (2003),<br></p>Fórmula:C13H18O3Forma y color:White To Off-WhitePeso molecular:222.283-Desmethoxy-3-bromo Trimethoprim
CAS:Producto controlado<p>Applications An impurity of Trimethoprim (T795615) with inhibitory effects on the enzyme dihydrofolate reductase.<br>References Kompis, I. et al.: Enzyme Inhib. Proc. Meet., 177 (1980); Hess, S. et al.: J. Pharmac. Biomed. Anal., 25, 531 (2001);<br></p>Fórmula:C13H15BrN4O2Forma y color:NeatPeso molecular:339.19Xipamide
CAS:Producto controlado<p>Applications Xipamide is a diuretic and antihypertensive agent.<br>References Wagieh, N., et al.: Drug Test. Anal., 2, 113 (2010), Prado-Prado, F., et al.: Bioorg. Med. Chem., 18, 2225 (2010), Dresen, S., et al.: Anal. Bioanal. Chem., 396, 2425 (2010),<br></p>Fórmula:C15H15ClN2O4SForma y color:NeatPeso molecular:354.81N-Desbutyl-N-(2-ethylhexyl) Bumetanide (~90% Purity)
CAS:<p>Applications N-Desbutyl-N-(2-ethylhexyl) Bumetanide is an analogue of the diuretic, Bumetanide (B689550).<br>References Petzinger, E. et al.: Am. J. Physiol., 265, G942 (1993);<br></p>Fórmula:C21H28N2O5SPureza:~90%Forma y color:NeatPeso molecular:420.52241-[4-(1-Hydroxy-2-methylpropyl)phenyl]ethanone
CAS:Fórmula:C12H16O2Forma y color:Light BrownPeso molecular:192.254Ibuprofen Isopropyl Ester
CAS:Producto controlado<p>Applications Ibuprofen Isopropyl Ester is a prodrug of Ibuprofen (I140000). It might improve topical delivery of ibuprofen.<br>References Bansal, A., et al.: Drug Dev. Ind. Pharm., 20, 2025 (1994); Bansal, A., et al.: Indian J. Exp. Bio., 39, 280 (2001)<br></p>Fórmula:C16H24O2Forma y color:NeatPeso molecular:248.36Piroxicam-d3
CAS:Producto controlado<p>Applications Non-steroidal anti-inflammatory with long half-life. Cyclooxygenase inhibitor. Clinically useful NSAID.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Carty, T.J., et al.: Prostaglandins, 47, 55 (1980), Brogden, R.N., et al.: Drugs, 22, 165 (1981), Mihalic, M., et al.: Anal. Profiles Drug Subs., 15, 509 (1986), Laneauville., O., et al.: J. Pharmacol. Exp. Ther., 271, 927 (1994),<br></p>Fórmula:C152H3H10N3O4SForma y color:NeatPeso molecular:334.36Gliquidone
CAS:Producto controlado<p>Applications Gliquidone is an anti diabetic agent used in the treatment of hypoglycemia which leads to an increased risk in diabetic cardiovascular disease. Also used in the treatment diabetic nephropathy.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Tan, Z. et al.: Chinese Med. J., 127, 1298 (2014); Ke, J, et al.: J. Endocrinol., 220, 129 (2014);<br></p>Fórmula:C27H33N3O6SForma y color:NeatPeso molecular:527.632,4-Dichlorobenzoic Acid
CAS:Producto controlado<p>Impurity Furosemide EP Impurity E<br>Applications 2,4-Dichlorobenzoic Acid (Furosemide EP Impurity E) is a di-halogenated benzoic acid derivative and an intermediate in the synthesis of spirodiclofen (S682990), a tetronic acid acaricide fungicide used in controlling red mites.<br>References Cho, Y.C., et al.: FEMS. MIcrobiol. Ecol., 42, 51 (2002); Corbella, M.E., et al.: Biodegradation., 12, 149 (2001);<br></p>Fórmula:C7H4Cl2O2Forma y color:White To Off-WhitePeso molecular:191.013-Methoxy Acetaminophen
CAS:<p>Applications 3-Methoxy Acetaminophen is a metabolite of Acetaminophen (A161220), an analgesic and antipyretic agent used as a pain reliever to treat headache, muscle aches, and arthritis (1,2,3).<br>References (1) McGill, M. R. and Jaeschke, H. Pharm Res. 30, 2174 (2013)(2) Fairbrother, J.E., et al.: Anal. Profiles Drug Subs., 3, 1 (1974) (3) Hinson, J.A., et al.: Rev. Biochem. Toxicol., 2, 103 (1980)<br></p>Fórmula:C9H11NO3Forma y color:NeatPeso molecular:181.194-Hydroxy-2H-1,2-benzothiazine-3-carboxylic acid ethyl ester 1,1-dioxide
CAS:<p>Piroxicam is a nonsteroidal anti-inflammatory drug (NSAID) that belongs to the group of carboxylic acid esters. It has been approved for the treatment of pain and inflammation caused by osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, and other conditions. Piroxicam is available in tablets, capsules, injectable solutions, and topical creams. The pharmacokinetics of piroxicam have been studied using intravenous and oral administration in healthy volunteers. Tolerability and side effects are minimal with piroxicam.</p>Fórmula:C11H11NO5SPureza:Min. 95%Forma y color:PowderPeso molecular:269.27 g/molAcetaminophen acetate
CAS:<p>Acetaminophen acetate is a cholinergic amine that binds to the active site of the enzyme acetylcholine esterase, preventing it from breaking down acetylcholine. Acetaminophen is used as a pain reliever and antipyretic agent. It is also used for its anti-inflammatory effects in the treatment of rheumatoid arthritis and other inflammatory conditions. Acetaminophen has been shown to have anticancer properties, which may be due to its ability to bind to cancer cells, inhibit their growth, and induce apoptosis. Acetaminophen acetate is also an acylation reaction product that can be isolated by liquid chromatography in phase with fluorescence properties.</p>Fórmula:C10H11NO3Pureza:Min. 95%Forma y color:White PowderPeso molecular:193.2 g/mol2-[4-(2-Methylpropanoyl)phenyl] propanoic acid
CAS:<p>2-[4-(2-Methylpropanoyl)phenyl] propanoic acid is a pharmaceutical intermediate that is used for the production of carprofen. It has been found to be an analytical method for the determination of 4-hydroxybenzoic acid and 4-isobutylacetophenone. The compound is analyzed by chromatographic methods and electrophoresis methods. The optimization of the solvent composition, flow rate, and impurities during the synthesis process are also studied in this research. 2-[4-(2-Methylpropanoyl)phenyl] propanoic acid has been found to be a meaningful validation of analytical methods for medicines, with an impurity limit of 0.1%.</p>Fórmula:C13H16O3Pureza:Min. 98 Area-%Forma y color:PowderPeso molecular:220.26 g/molN4-Acetyl sulfadoxine
CAS:<p>N4-Acetyl sulfadoxine is a drug that is used to treat urinary tract infections in women and children. It is also used to treat bacterial infections of the skin, lungs, and joints. N4-Acetyl sulfadoxine may be effective against prostatitis caused by E. coli or Mycoplasma pneumoniae by inhibiting the production of prostaglandins. This drug works by binding to dihydropteroate synthase, which prevents folic acid from being incorporated into the bacterial cell wall, thereby inhibiting bacterial growth.</p>Fórmula:C14H16N4O5SPureza:Min. 95%Forma y color:PowderPeso molecular:352.37 g/mol4-Hydroxy-2-methyl-2H-1,2-benzothiazine-3-carboxylic acid, ethyl ester 1,1-dioxide
CAS:<p>4-Hydroxy-2-methyl-2H-1,2-benzothiazine-3-carboxylic acid, ethyl ester 1,1-dioxide (4HMBC) is an organic compound that is used as a precursor in the synthesis of other chemicals. 4HMBC is used to produce xylene, sulfoxide and diethyl ether by reacting with magnesium and ethylene. It is also used in the production of dimethylformamide, a solvent that is useful for the manufacture of many products including pharmaceuticals. 4HMBC reacts with methyl iodide to form 4-(dimethylamino)pyridine which can be used for the synthesis of piroxicam. The chemical has been shown to be effective as an insecticide against ants and cockroaches. It can also be used to synthesize dyes or pigments. The chemical can be obtained by methylating 4HBC with methanol in the presence</p>Fórmula:C12H13NO5SPureza:Min. 95%Forma y color:PowderPeso molecular:283.3 g/mol
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