Sulfonamidas y derivados
Las sulfonamidas son compuestos que contienen un grupo funcional sulfonamida (-SO₂NH₂), en el que un átomo de azufre está unido a un grupo amino. Fueron de los primeros antibióticos sintéticos utilizados en medicina, inhibiendo la síntesis de ácido fólico en bacterias, lo que les confiere propiedades antimicrobianas. Se utilizan principalmente para tratar infecciones bacterianas, aunque hoy en día su uso se ha visto reducido debido a la resistencia antimicrobiana. Además de su uso en antibióticos, las sulfonamidas también tienen aplicaciones en el tratamiento de enfermedades como la malaria y enfermedades inflamatorias intestinales.
En CymitQuimica ofrecemos sulfonamidas y sus derivados con alto grado de pureza para investigación en microbiología y desarrollo farmacéutico.
Se han encontrado 2592 productos de "Sulfonamidas y derivados"
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Mesotrione
CAS:<p>Mesotrione is a selective triketone herbicide</p>Fórmula:C14H13NO7SPureza:99.39%Forma y color:Light Yellow Crystalline PowderPeso molecular:339.32Quinine hydrochloride dihydrate
CAS:<p>Quinine hydrochloride dihydrate (Quinine HCl Dihydrate) is a white crystalline K+ channel blocker, used to treat malaria.</p>Fórmula:C20H24N2O2·HCl·2H2OPureza:99.91%Forma y color:White To Light Yellow Crystal PowderPeso molecular:396.912-(4-Isobutylphenyl)propanal
CAS:<p>Stability Hygroscopic<br>Applications 2-(4-Isobutylphenyl)propanal is an impurity of the drug Ibuprofen (I140000), a selective cyclooxygenase inhibitor that also inhibits PGH synthase-1 and PGH synthase-2 with comparable potency.<br>References Busson, M., et al.: J. Int. Med Res., 14, 53 (1986), Meade, E.A., et al.: J. Biol. Chem., 268, 6610 (1993), Davies, N.M., et al.: Clin. Pharmacokinet., 34, 101 (1998); (4) Chem. and Eng. News p9, July 4 (2016)<br></p>Fórmula:C13H18OForma y color:NeatPeso molecular:190.28Gliclazide
CAS:<p>Applications A sulfonylurea hypoglycemic agent. Used as an antidiabetic.<br>References Duhault, J., et al.: Arzneimittel-Forsch., 22, 1686 (1972), Holmes, B., et al.: Drugs, 27, 301 (1984),<br></p>Fórmula:C15H21N3O3SForma y color:NeatPeso molecular:323.414-Nitro-2-phenoxyaniline
CAS:<p>Impurity Nimesulide EP Impurity D<br>Stability Light Sensitive<br>Applications 4-Nitro-2-phenoxyaniline has been shown to have good AT1 Angiotension Receptor Antagonist activity when combined with Schiff bases.<br>References Shreenivas, M.T., et. al.: J. Pharm. Sci. Technol., 1, 88 (2009)<br></p>Fórmula:C12H10N2O3Forma y color:YellowPeso molecular:230.22Glyburide-d3 (methoxy-d3)
CAS:Producto controlado<p>Applications Glyburide-d3 (methoxy-d3) (CAS# 1219803-02-7) is a useful isotopically labeled research compound.<br></p>Fórmula:C23D3H25ClN3O5SForma y color:NeatPeso molecular:497.0224-Acetaminophen Sulfate Potassium Salt
CAS:Producto controladoFórmula:C8H8NO5S·KForma y color:BeigePeso molecular:269.32Iso Furosemide
CAS:<p>Impurity Furosemide EP Impurity A<br>Applications Iso Furosemide (Furosemide EP Impurity A) is a Furosemide (F865000) derivative which enhanced urinary excretion of active kallikrein.<br>References Kirk, K., et al.: J. Biol. Chem., 267, 23475 (1992), Kirk, K., et al.: Biochem. J., 311, 761 (1995), Egee, S., et al.: J. Physiol., 542, 795 ( 2002),<br></p>Fórmula:C12H11ClN2O5SForma y color:Light BrownPeso molecular:330.74Dapsone
CAS:Producto controlado<p>Applications An antibacterial used in the treatment of dermatitis herpetiformis.<br>References Francis, J., et al.: Br. J. Pharmacol., 5, 565 (1950), Uetrecht, J., et al.: Clin. Dermatol., 7, 111 (1989); Reszka, K., et al.: Chem. Res. Toxicol., 22, 1137 (2009), Santos, J., et al.: Bioorg. Med. Chem., 17, 3795 (2009), Varma, M., et al.: J. Med. Chem., 52, 4844 (2009),<br></p>Fórmula:C12H12N2O2SForma y color:NeatPeso molecular:248.30Sulfamethoxazole N4-glucoside (α/β mixture)
CAS:<p>Applications Sulfamethoxazole N4-glucoside is a metabolite of Sulfamethoxazole (S699086) which is an anti bacterial drug. Sulfonamide antibiotic that blocks the synthesis of dihydrofolic acid by inhibiting the enzyme dihydropteroate synthase.<br>References Rudy, B.C., et al.: Anal. Profiles Drug Subs., 2, 467 (1973), Wormser, G.P., et al.: Drugs, 24, 459 (1982), Wharton, M., et al.: Ann. Intern. Med., 105, 37 (1986),<br></p>Fórmula:C16H21N3O8SForma y color:White To Light Orange ColourPeso molecular:415.42Sulfasalazine 3-Isomer
CAS:Producto controlado<p>Impurity Sulfasalazine EP Impurity F<br>Stability Hygroscopic<br>Applications A positional isomeric impurity of Sulfasalazine (S699084). Sulfasalazine EP Impurity F<br>References Zalipsky, J.J. et al.: J. Pharmac. Sci., 67, 387 (1978);<br></p>Fórmula:C18H14N4O5SForma y color:NeatPeso molecular:398.39Aceclofenac Methyl Ester
CAS:Producto controlado<p>Impurity Aceclofenac EP Impurity D<br>Applications Aceclofenac Methyl Ester (Aceclofenac EP Impurity D) is a 2-[(2,6-dichlorophenyl)amino]phenylacetoxyacetyl derivative as anti-inflammmatory and analgesic agent.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>Fórmula:C17H15Cl2NO4Forma y color:Off-WhitePeso molecular:368.21Sulfamethizole
CAS:<p>Applications Sulfamethizole is a sulfonamide based antibiotic that exhibit bactericidal activities towards gram-negative bacteria. Sulfamehizole was shown to be effective in treating gram-negative Bacillus AmpC enzyme in elderly patients with lower respiratory tract infection and as well as against microbs responsible for tuberculosis.<br>References Mondelli, M., et al.: J. Molec. Struct., 1036, 180 (2013); Leelakrishnana, S., et al.: Adv. App. Sci. Res., 3, 3502 (2012); Ghoreishi, S.M., et al.: Anal. Lett., 46, 323 (2012);<br></p>Fórmula:C9H10N4O2S2Forma y color:WhitePeso molecular:270.33132-(p-sec-Butylphenyl)propionic Acid
CAS:Producto controlado<p>Impurity Ibuprofen EP Impurity O<br>Applications 2-(p-sec-Butylphenyl)propionic Acid (Ibuprofen EP Impurity O) is an impurity of Ibuprofen (I140000); a selective cyclooxygenase inhibitor (IC50=14.9uM) that inhibits PGH synthase-1 and PGH synthase-2 with comparable potency.<br>References Busson, M., et al.: J. Int. Med Res., 14, 53 (1986); Meade, E.A., et al.: J. Biol. Chem., 268, 6610 (1993); Davies, N.M., et al.: Clin. Pharmacokinet., 34, 101 (1998)<br></p>Fórmula:C13H18O2Forma y color:NeatPeso molecular:206.28Trimethoprim-d9 (Major)
CAS:Producto controlado<p>Applications Deuterated Trimethoprim, an antibacterial.contains 90% D9, 10% D6 and no D0<br>References Manius, G.J., et al.: Anal. Profiles Drug Subs., 7, 445 (1978), Roth, B., et al.: J. Med. Chem., 23, 379 (1980), Brogden, R.N., et al.: Drugs, 23, 405 (1982),<br></p>Fórmula:C14D9H9N4O3Forma y color:Off-WhitePeso molecular:299.37Glibornuride
CAS:Producto controlado<p>Applications Glibornuride has been shown to antagonize the relaxant response to the K+ channel opener cromakalim and produce airway smooth muscle relaxation. Glibornuride is associated with lactic acidosis and hypoglycemia in patients with type 2 diabetes melitus.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Mielsen-Kudsk, J.E., Thirstrup, S.: Pulm. Pharmacol., 6, 185 (1993); Bodmer, M., et. al.: Diabetes Care, 31, 2086 (2008)<br></p>Fórmula:C18H26N2O4SForma y color:White To Off-WhitePeso molecular:366.485-Chloro Hydrochlorothiazide
CAS:Producto controlado<p>Impurity Hydrochlorothiazide 5-Chloro Impurity<br>Applications Hydrochlorothiazide derivative. Diuretic agent.<br>References Mayer, S.E., et al.: J. Pharmacol. Exp. Therap., 134, 18 (1961),<br></p>Fórmula:C7H7Cl2N3O4S2Forma y color:Off White SolidPeso molecular:332.182,3-Dimethyl-N-phenylbenzenamine
CAS:Producto controlado<p>Applications 2,3-Dimethyl-N-phenylbenzenamine is a lipophilic compound that is a commonly used non-steroidal anti-inflammatory drug (NSAID).<br>References El Haj, B. M., et al.: Forensic Sci. Int., 105, 141 (1999); Velkov, T., et al.: Chem. Biol., 14, 453 (2007)<br></p>Fórmula:C14H15NForma y color:White To BeigePeso molecular:197.28Saccharin N-(2-Acetic Acid Ethyl Ester)(Piroxicam Impurity E)
CAS:Producto controlado<p>Impurity Piroxicam EP Impurity E<br>Applications Piroxicam impurity E.<br>References Lombardino, J., et al.: J. Med. Chem., 14, 1171 (1971), Turck, D., et al.: Clin. Drug Invest., 9, 270 (1995),<br></p>Fórmula:C11H11NO5SForma y color:White To Off-WhitePeso molecular:269.27(S)-(+)-Ibuprofen-d3
CAS:Producto controlado<p>Applications A labelled nonsteroidal anti-inflammatory drug (NSAID); activity resides primarily in the (S)-isomer.<br>References Busson, M., et al.: J. Int. Med Res., 14, 53 (1986), Meade, E.A., et al.: J. Biol. Chem., 268, 6610 (1993), Davies, N.M., et al.: Clin. Pharmacokinet., 34, 101 (1998),<br></p>Fórmula:C13H15D3O2Forma y color:NeatPeso molecular:209.3Nicosulfuron
CAS:Producto controlado<p>Stability Hygroscopic, Unstable in DMSO<br>Applications Post-emergence sulfonylurea herbicide.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Gubbiga, N.G., et al.: Weed Technol., 9, 574 (1995), Ukrainczyk, L., et al.: J. Agric. Food Chem., 43, 855 (1995)<br></p>Fórmula:C15H18N6O6SForma y color:White To Off-WhitePeso molecular:410.40meta-Glimepiride Impurity.
CAS:Producto controladoFórmula:C24H34N4O5SForma y color:WhitePeso molecular:490.62Acetaminophen Glutathione-d3 Disodium Salt (~90%)
CAS:Producto controladoFórmula:C18H19D3N4Na2O8SPureza:~90%Forma y color:Off-White To Dark BrownPeso molecular:503.45Trimethoprim Lactate Salt
CAS:Producto controlado<p>Applications Trimethoprim lactate salt is an antibacterial agent.<br>References Lees, G. et al.: Brit. J. Pharmacol., 73, 535 (1981);<br></p>Fórmula:C14H18N4O3·C3H6O3Forma y color:NeatPeso molecular:290.32 + (90.08)2,4'-Diaminophenyl Sulfone
CAS:Producto controladoFórmula:C12H12N2O2SForma y color:NeatPeso molecular:248.30088Niflumic Acid-d5 (Major)
CAS:Producto controlado<p>Applications Anti-inflammatory. Selective cyclooxygenase-2 (COX-2) inhibitor.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Glasson, et al.: Biochem, Pharmacol., 18, 633 (1969), Boissier, et al.: Therapie, 26, 211 (1971), Sorenson, J.R.J., et al.: J. Med. Chem., 19, 135 (1976), Barnett, J., et al.: Biochim. Biophys. Acta, 1209, 130 (1994), Johnson, J.L., et al.: Arch. Biochem. Biophys., 324, 26 (1995),<br></p>Fórmula:C13H4D5F3N2O2Forma y color:NeatPeso molecular:287.254-Amino-4'-hydroxydiphenylsulfone
CAS:<p>Stability Hygroscopic<br>Applications 4-Amino-4'-hydroxydiphenylsulfone is a diaryl sulfone with antileprotic activity. 4-Amino-4'-hydroxydiphenylsulfone is an antibacterial agent.<br>References Colwell, W.T. et al.: J. Med. Chem., 17, 142 (1974); Agrawal, V.K. et al.: Acta Microb iol. Immunol. Hung., 50, 385 (2003);<br></p>Fórmula:C12H11NO3SForma y color:Light BrownPeso molecular:249.291-Cyclohexyl-3-(p-sulfamoylphenethyl)urea
CAS:Producto controlado<p>Impurity Glipizide EP Impurity H<br>Applications 1-Cyclohexyl-3-(p-sulfamoylphenethyl)urea (Glipizide EP Impurity H) is an impurity of Glipizide (G410225).<br>References Jurca, B. et al.: J. Therm. Anal. Calor., 62, 859 (2000);<br></p>Fórmula:C15H23N3O3SForma y color:WhitePeso molecular:325.43N-(1-Phenylethyl) Ibuprofen Amide(Mixture of 4 Diastereomers)
CAS:Producto controlado<p>Applications Ibuprofen (I140000) impurity, an anti-inflammatory compound.<br>References Rubin, A., et al.: J. Pharm. Sci., 74, 82 (1985), Tracy, T., et al.: Drug Metab. Dispos., 20, 322 (1992),<br></p>Fórmula:C21H27NOForma y color:WhitePeso molecular:309.45Penoxsulam
CAS:<p>Applications Penoxsulam is an acetolactate synthase inhibitor herbicide developed for controlling grasses, sedges, and broadleaf weeds in rice culture.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Jabusch, T., and Tjeerdema, R.: J. Agric. Food Chem. 53, 18, 7179-183 (2005); Bamcjero, M., et al.: Sci. Total Environ. 807, 1, 160793 (2021)<br></p>Fórmula:C16H14F5N5O5SForma y color:White To Light BrownPeso molecular:483.37[4-[2-[[(3-Ethyl-2,5-dihydro-4-methyl-2-oxo-1H-pyrrol-1-yl)carbonyl]amino]ethyl]phenyl]sulfonyl]carb
CAS:Producto controlado<p>Impurity Glimepiride Ethyl Ester Impurity<br>Applications Intermediate for the preparation of Glimepiride (G410150) and some substituted sulfonyl urea antidiabetics. Glimepiride Ethyl Ester Impurity<br></p>Fórmula:C19H25N3O6SForma y color:NeatPeso molecular:423.48N-Acetyl Sulfadiazine-13C6
CAS:Producto controlado<p>Applications A major metabolite of Sulfadiazine.<br>References Woolley, J., et al.: Drug Metab. Dispos., 7, 94 (1979), Nielsen, P., et al.: Biochem. Pharmacol., 35, 2509 (1986), Anari, M., et al.: Anal. Chem., 76, 823 (2004), Edlund, P., et al.: J. Pharm. Biomed. Anal., 34, 1079 (2004),<br></p>Fórmula:C613C6H12N4O3SForma y color:NeatPeso molecular:298.27Acetazolamide Disulphide Impurity
CAS:<p>Impurity Acetazolamide Disulphide Impurity<br>Applications bis(2-Acetamido-1,3,4-thiadiazol-5-yl) Disulfide is an impurity of Acetazolamide (A161500), a carbonic anhydrase inhibitor. Diuretic. (Acetazolamide Disulphide Impurity)<br>References Srinivasu, P., et. al.: J. Pharmaceut. Biomed. Anal., 52, 142 (2010); Vitale, R., et al.: J. Med. Chem., 52, 5990 (2009); Bell, H., et al.: Am. J. Physiol., 297, R370 (2009); Maresca, A., et al.: Bioorg. Med. Chem. Lett., 19, 4929 (2009); Liu, Y., et al.: Anal. Bioanal. Chem., 395, 591 (2009)<br></p>Fórmula:C8H8N6O2S4Forma y color:NeatPeso molecular:348.45Bumetanide Butyl Ester
CAS:Producto controlado<p>Applications Bumetanide Butyl Ester is an intermediate in the preparation of Bumetanide<br>References Petzinger, E., et al.: Am. J. Physiol., 265, G942 (1993);<br></p>Fórmula:C21H28N2O5SForma y color:NeatPeso molecular:420.52Acetaminophen Acetate (Acetaminophen Impurity)
CAS:<p>Impurity Paracetamol EP Impurity H/ Acetaminophen impurity H<br>Applications Acetaminophen Acetate is an impurity of Acetaminophen (A161220), an analgesic and antipyretic agent used as a pain reliever to treat headache, muscle aches, and arthritis (1,2,3).<br>References (1) McGill, M. R. and Jaeschke, H. Pharm Res. 30, 2174 (2013)(2) Fairbrother, J.E., et al.: Anal. Profiles Drug Subs., 3, 1 (1974) (3) Hinson, J.A., et al.: Rev. Biochem. Toxicol., 2, 103 (1980)<br></p>Fórmula:C10H11NO3Forma y color:White To Off-WhitePeso molecular:193.20Sulfadoxine
CAS:Producto controlado<p>Applications Used as an antibacterial.<br>References Kapoor, V.K., et al.: Anal. Profiles Drug Subs., 17, 571 (1988)<br></p>Fórmula:C12H14N4O4SForma y color:WhitePeso molecular:310.33Dapsone Hydroxylamine
CAS:<p>Stability Light Sensitive, Temperature Sensitive<br>Applications A metabolite of Dapsone.<br>References Preuss, C.V., et al.: Biochem. Pharmacol., 51, 1661 (1996), F., et al.: J. Pharmacol. Exp. Ther., 323, 771 (2007), Roychowdhury, S., et al.: Drug Metab. Disposition, 35, 676 (2007), Obach, R., et al.: Environ. Mol. Mutagen., 49, 631 (2008), Veggi, L., et al.: Life Sci., 83, 155 (2008), Khan,<br></p>Fórmula:C12H12N2O3SForma y color:Off-WhitePeso molecular:264.30Azoxydapsone
CAS:Producto controlado<p>Applications Azoxydapsone is a primary urinary N-oxidation metabolite of Dapsone (D193250); an antibacterial used in the treatment of dermatitis herpetiformis.<br>References Israili, Z.H., et al.: J. Pharmacol. Exp. Ther., 187, 138 (1973); Cucinell, S.A., et al.: Am. J. Trop. Med. Hyg., 21, 322 (1972); Francis, J., et al.: Br. J. Pharmacol., 5, 565 (1950); Uetrecht, J., et al.: Clin. Dermatol., 7, 111 (1989); Reszka, K., et al.: Chem. Res. Toxicol., 22, 1137 (2009); Santos, J., et al.: Bioorg. Med. Chem., 17, 3795 (2009); Varma, M., et al.: J. Med. Chem., 52, 4844 (2009)<br></p>Fórmula:C24H20N4O5S2Forma y color:NeatPeso molecular:508.57Sulfacetamide
CAS:Producto controlado<p>Applications Sulfacetamide is an antibiotic used for the treatment of skin infections and urinary tract infections. Sulfacetamide is also used to treat acne and seborrheic dermatitis. Sulfacetamide was investigated for potential anti-inflammatory properties<br>References Wittwer, M.B., et al.: J. Med. Chem., 56, 781 (2013); Wang. X., et al.: Afr. J. Micriobiol., 6, 4533 (2012); Yu, B., et al.: Euro. J. Med. Chem., 46, 5833 (2011);<br></p>Fórmula:C8H10N2O3SForma y color:Off-WhitePeso molecular:214.24
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