Sulfonamidas y derivados
Las sulfonamidas son compuestos que contienen un grupo funcional sulfonamida (-SO₂NH₂), en el que un átomo de azufre está unido a un grupo amino. Fueron de los primeros antibióticos sintéticos utilizados en medicina, inhibiendo la síntesis de ácido fólico en bacterias, lo que les confiere propiedades antimicrobianas. Se utilizan principalmente para tratar infecciones bacterianas, aunque hoy en día su uso se ha visto reducido debido a la resistencia antimicrobiana. Además de su uso en antibióticos, las sulfonamidas también tienen aplicaciones en el tratamiento de enfermedades como la malaria y enfermedades inflamatorias intestinales.
En CymitQuimica ofrecemos sulfonamidas y sus derivados con alto grado de pureza para investigación en microbiología y desarrollo farmacéutico.
Se han encontrado 2589 productos de "Sulfonamidas y derivados"
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Decarboxy Etodolac
CAS:Producto controlado<p>Impurity Etodolac EP Impurity J<br>Applications Decarboxy Etodolac (Etodolac EP Impurity J) is an impurity of Etodolac (racemic, E933100), which is a non-steroidal anti-inflammatory drug (NSAID) that selectively inhibits cyclooxygenase-2 (COX-2). Etodolac displays anti-inflammatory effects in both adjuvant arthritic and normal rats. Etodolac is anti-inflammatory.<br>References Humber, L.G., et al.: Med. Res. Rev., 7, 1 (1987); Balfour, J.A, et al.: Drugs, 42, 274 (1991); Kato, et al.: J. Pharm. Pharmacol., 53 1679 (2001)<br></p>Fórmula:C16H21NOForma y color:White To YellowPeso molecular:243.342-Chlorobenzoic Acid
CAS:<p>Impurity Mesalazine EP Impurity L<br>Applications The toxicity of halogenated benzoic acids was found to be directly related to the compound's hydrophobicity. Toxicity and quantitative structure-activity relationships of benzoic acids to Pseudokirchneriella subcapitata.<br>References Moore, D., et al.: Environ. Toxicol. Chem., 16, 794 (1997), Zhao, Y., et al.: Sci. Total Environ., 216, 205 (1998), Fiorentino, A., et al.: J. Agric.Food Chem., 51, 1005 (2003),<br></p>Fórmula:C7H5ClO2Forma y color:NeatPeso molecular:156.572,7-Diamino-6-phenyl-4-pteridinol
CAS:Producto controlado<p>Impurity Triamterene EP Impurity B/ Triamterene USP Related Compound B<br>Applications 2,7-Diamino-6-phenyl-4-pteridinol has potential as a pteridine diuretic. Impurity in the synthesis of Triamterene (T767325), a weak diuretic with potassium sparing properties; blocks Na+ reuptake in the kidneys.<br>References Osdene, et al.: J. Med. Chem., 10, 431 (1967), Kapoor, V.K., et al.: Anal. Profiles Drug Subs. Excip., 23, 571 (1994); Weinstock, J. et al.: J. Med. Chem., 11, 573 (1968);<br></p>Fórmula:C12H10N6OForma y color:NeatPeso molecular:254.25Mordant Yellow 10 (Technical Grade)
CAS:Producto controlado<p>Impurity Sulfasalazine Impurity I<br>Stability Light Sensitive<br>Applications Mordant Yellow 10 is a monoazo dye used in wool textiles. Mordant Yellow 10 is used as organic reagent for spectrometric determination of iron(III) as well as in the study of other metal complexations.<br>References Ledneva, I.A. Izvest. Vyssh. Ucheb. Zav. Tekh. Teks. Prom., 5, 58 (1986); Vladescu, L. et al.: Rev. Roum. Chem., 54, 85 (2009); Gupta, P.N. et al.: Asian J. Chem., 4, 15 (1992);<br></p>Fórmula:C13H8N2O6S·2NaForma y color:NeatPeso molecular:366.264-Acetaminophen-d3 Sulfate
CAS:Producto controlado<p>Applications 4-Acetaminophen-d3 Sulfate is deuterium labeled metabolite of Acetaminophen (A161220), an analgesic and antipyretic agent (1,2,3).<br>References (1) Lloyd, A., et al.: Biochim. Biophys. Acta., 52, 413 (1961) (2) Purohit, A., et al.: J. Steroid Biochem. Mol. Biol., 86, 423 (2003) (3) Winum, J., et al.: J. Med. Chem., 46, 2197 (2003)<br></p>Fórmula:C82H3H6NO5SForma y color:White To Off-WhitePeso molecular:234.243-Hydroxyacetaminophen
CAS:Producto controlado<p>Applications 3-Hydroxyacetaminophen is a metabolite of Acetaminophen (A161220), an analgesic and antipyretic agent used as a pain reliever to treat headache, muscle aches, and arthritis (1,2,3).<br>References (1) Chen, C., et al.: J. Biol. Chem., 283, 4543 (2008)(2) Reith, D., et al.: Clin. Exper. Pharmacol. Physiol., 36, 35 (2009) (3) McGill, M. R. and Jaeschke, H. Pharm Res. 30, 2174 (2013)<br></p>Fórmula:C8H9NO3Forma y color:NeatPeso molecular:167.16(3RS)-1,3-Bis[4,-2-(methylpropyl)phenyl]butan-1-one
CAS:Producto controladoFórmula:C24H32OForma y color:Colourless To Light YellowPeso molecular:336.51Tolbutamide-d9
CAS:Producto controladoFórmula:C122H9H9N2O3SForma y color:White To Off-WhitePeso molecular:279.40Sulfathiazole
CAS:Producto controlado<p>Applications Antibacterial.This compound is a contaminant of emerging concern (CECs).<br>References Kapoor, V.K., et al.: Anal. Profiles Drug Subs. Excip., 22, 389 (1993),<br></p>Fórmula:C9H9N3O2S2Forma y color:WhitePeso molecular:255.325-Amino-1,3,4-thiadiazole-2-sulfonamide Hydrochloride Salt
CAS:Producto controlado<p>Impurity Acetazolamide EP Impurity D Hydrochloride<br>Applications Acetazolamide intermediate. (Acetazolamide EP Impurity D Hydrochloride)<br>References Carta, F., et al.: Bioorg. Med. Chem. Lett., 19, 6649 (2009), Joseph, P., et al.: J. Med. Chem., 53, 2277 (2010), Srinivasu, P., et al.: J. Pharm. Biomed. Anal., 52, 142 (2010),<br></p>Fórmula:C2H5ClN4O2S2Forma y color:NeatPeso molecular:216.67Trimethoprim-d3
CAS:Producto controlado<p>Applications Deuterated Trimethoprim, an antibacterial.<br>References Manius, G.J., et al.: Anal. Profiles Drug Subs., 7, 445 (1978), Roth, B., et al.: J. Med. Chem., 23, 379 (1980), Brogden, R.N., et al.: Drugs, 23, 405 (1982),<br></p>Fórmula:C14D5H15N4O3Forma y color:Off WhitePeso molecular:297.3643-Oxo-1,2-benzoisothiazoline-2-acetic Acid Methyl Ester 1,1-Dioxide
CAS:<p>Impurity Piroxicam EP Impurity D<br>Applications Piroxicam impurity D.<br>References Lombardino, J., et al.: J. Med. Chem., 14, 1171 (1971), Turck, D., et al.: Clin. Drug Invest., 9, 270 (1995),<br></p>Fórmula:C10H9NO5SForma y color:NeatPeso molecular:255.25Ibuprofen Alcohol
CAS:Producto controlado<p>Applications Ibuprofen Alcohol (Ibuprofen EP Impurity P) is an impurity of Ibuprofen (I140000). Ibuprofen impurity P as per EP.<br>References Haikala, V., et al.: J. Pharm. Sci., 80, 456 (1991), Zhao, J., et al.: Anal. Chem., 72, 302 (2000), Kucera, R., et al.: J. Pharm. Biomed. Anal., 38, 609 (2005),<br></p>Fórmula:C13H20OForma y color:Colourless To Light YellowPeso molecular:192.306,6'-Oxybis-2-naphthalenesulfonic Acid Disodium Salt (>85%)
CAS:Producto controlado<p>Applications An impurity contained in the commercial food Yellow No.5 (Sunset Yellow FCF) which has a potent mutagenicity effect.<br>References Yamada, M., et al.: Chem. Pharm. Bull., 44, 1624 (1996), Yamada, M., et al.: J. Food Chem., 3, 151 (1996),<br></p>Fórmula:C20H12O7S2·2NaPureza:>90%Forma y color:White To Light GreyPeso molecular:474.41Glimepiride
CAS:<p>Applications A sulfonylurea hypoglycemic agent. Used as an antidiabetic.<br>References Ratheiser, K., et al.: Arzneim.-Forsch., 43, 856, (1993),<br></p>Fórmula:C24H34N4O5SForma y color:NeatPeso molecular:490.624-Nitro Sulfamethoxazole
CAS:Producto controlado<p>Applications A Sulfamethoxazole metabolite.<br>References Gill, H., et al.: Br. J. Clin. Pharmacol., 42, 347 (1996), Winter, H., et al.: Clin. Pharmacol. Ther., 76, 579 (2004), Vyas, P., et al.: Biochem. Pharmacol., 70, 275 (2005), Vyas, P., et al.: Drug Metab. Dispos., 34, 16 (2006),<br></p>Fórmula:C10H9N3O5SForma y color:Light BrownPeso molecular:283.263-Desmethyl Trimethoprim
CAS:Producto controlado<p>Applications 3-Desmethyl Trimethoprim is a metabolite of Trimethoprim (T795615); an antibacterial agent that is commonly prescribed in conjunction with Sulfametoxazole (S699086) to treat patients afflicted with urinary tract infections. 3-Desmethyl Trimethoprim gets excreted in the urine of rats, dogs, and man in the form of glucuronides.<br>References Roth, B., et al.: J. Med. Chem., 24, 933 (1981); Liu, Z., et al.: Biomed. Chromatogr., 26, 1101 (2012); Schwartz, D. E., Arzneimittel-Forsch., 20, 1867 (1970)<br></p>Fórmula:C13H16N4O3Forma y color:White To Light BrownPeso molecular:276.29Diacetic Aceclofenac
CAS:Producto controlado<p>Impurity Aceclofenac EP Impurity H<br>Applications A 2-[(2,6-dichlorophenyl)amino]phenylacetoxyacetyl derivative as anti-inflammmatory and analgesic agent. (Aceclofenac EP Impurity H)<br></p>Fórmula:C20H17Cl2NO8Forma y color:White To Off-WhitePeso molecular:470.26Terizidone
CAS:Producto controlado<p>Applications A drug used to treat tuberculosis.<br>References Marrero-Ponce, Y., et al.: Bioorg. Med. Chem., 13, 2881 (2005),<br></p>Fórmula:C14H14N4O4Forma y color:NeatPeso molecular:302.294-Hydroxy Trimethoprim
CAS:<p>Applications Trimethoprim (T795615) derivative. Antibacterial properties.<br></p>Fórmula:C14H18N4O4Forma y color:NeatPeso molecular:306.32Pyroxasulfone
CAS:Producto controlado<p>Applications Pyroxasulfone is an inhibitor of the biosynthesis of very-long-chain fatty acids. Pyroxasulfone is also used to control grass weed species in pre-emergence in major field crops.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Busi, R., et al.: Pest. Manag. Sci., 72, 1665 (2016)<br></p>Fórmula:C12H14F5N3O4SForma y color:WhitePeso molecular:391.31Napropamid
CAS:<p>Applications Napropamid is used as a pesticide.<br>References She-feng, J., et al.: Nanjing Nongye Daxue Xuebao, 35, 137 (2012);<br></p>Fórmula:C17H21NO2Forma y color:Light Orange Color To Light BrownPeso molecular:271.35Phenacetin
CAS:Producto controlado<p>Applications Analgesic, antipyretic. Component of APC tablets, analgesic mixture also containing aspirin and caffeine. Phenacetin is reasonably anticipated to be a human carcinogen; analgesic mixtures containing Phenacetin are listed as known human carcinogens.<br>References Boyd, et al.: Toxicol. Appl. Pharmacol., 1, 240 (1959), Dubach, C.U., et al.: N. Engl. J. Med., 308, 357 (1983),<br></p>Fórmula:C10H13NO2Forma y color:WhitePeso molecular:179.22Despyridyl Piroxicam (Piroxicam Impurity C)
CAS:Producto controladoFórmula:C10H10N2O4SForma y color:NeatPeso molecular:254.261,8-Diethyl-1,3,4,9-tetrahydro-pyrano[3,4-b]indole-1-acetic Acid Methyl Ester
CAS:<p>Impurity Etodolac EP Impurity K<br>Applications 1,8-Diethyl-1,3,4,9-tetrahydro-pyrano[3,4-b]indole-1-acetic Acid Methyl Ester (Etodolac EP Impurity K) is a derivative of Etodolac.<br>References Caldwell, J., et al.: Biochem. Pharmacol., 37, 105 (1988), Drummer, O., et al.: J. Anal. Toxicol., 17, 225 (1993)<br></p>Fórmula:C18H23NO3Forma y color:White To Off-WhitePeso molecular:301.38Diclosan
CAS:<p>Applications Diclosan is used in the treatment of halogenated phenolic compounds by sequential tri-metal reduction and laccase-catalytic oxidation.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Dai, Y., et al.: Water Res., 71, 64 (2015);<br></p>Fórmula:C12H8Cl2O2Forma y color:White PowderPeso molecular:255.10Acetanilide (Acetylaniline)
CAS:Producto controlado<p>Impurity Paracetamol EP Impurity D<br>Applications Acetanilide (Acetylaniline) the first aniline derivative found to possess analgesic and antipyretic properties (1,2). It is also an impurity of Acetaminophen (A161220).<br>References (1) Gohil, V., et al.: Nat. Biotechnol., 28, 249 (2010) (2) Chang, C., et al.: J. Nat. Prod., 73, 229 (2010)<br></p>Fórmula:C8H9NOForma y color:White To Light BrownPeso molecular:135.16Furosemide
CAS:Producto controlado<p>Applications Furosemide inhibits ion co-transport in the kidney. Furosemide is used as a diuretic. Non-competitve subtype-specific blocker of GABAA. Neuroprotective & Neuroresearch Products.<br>References Goldenthal, E.I.: Toxicol. Appl. Pharmacol., 18, 185 (1971), Benet, L.Z.: J. Pharmacokinet. Biopharm., 7, 1 (1979); Korpi, E. et al.: Mol. Pharmacology, 47, 283 (1995);<br></p>Fórmula:C12H11ClN2O5SForma y color:White To Off-WhitePeso molecular:330.74Niflumic Acid
CAS:Producto controlado<p>Applications Anti-inflammatory. Selective cyclooxygenase-2 (COX-2) inhibitor.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Glasson, et al.: Biochem, Pharmacol., 18, 633 (1969), Boissier, et al.: Therapie, 26, 211 (1971), Sorenson, J.R.J., et al.: J. Med. Chem., 19, 135 (1976), Barnett, J., et al.: Biochim. Biophys. Acta, 1209, 130 (1994), Johnson, J.L., et al.: Arch. Biochem. Biophys., 324, 26 (1995),<br></p>Fórmula:C13H9F3N2O2Forma y color:Light YellowPeso molecular:282.22Ibuprofen Carboxylic Acid(Mixture of Diastereomers)
CAS:Producto controlado<p>Applications The major metabolite of Ibuprofen; may reduce the risk of cataract by protecting lenticular enzymes.<br>References Bhuyan, K., et al.: Life Sci., 38, 1463 (1986), Blakytny, R., et al.: Biochem. J., 288, 303 (1992),Ganea, E., et al.: Eur. J. Biochem., 231, 181 (1995), Mitchell, J., et al.: Br. J. Pharmacol., 128, 1121 (1999),<br></p>Fórmula:C13H16O4Forma y color:White SolidPeso molecular:236.264'-Isopropylacetophenone
CAS:Producto controladoFórmula:C11H14OForma y color:NeatPeso molecular:162.234-Acetamidobenzenesulfonic Acid
CAS:Producto controlado<p>Impurity Sulfadimethoxine EP Impurity C<br>Stability Hygroscopic<br>Applications 4-Acetamidobenzenesulfonic Acid (Sulfadimethoxine EP Impurity C) is a metabolite of Sulfanilic acid.<br>References Saab, N., et al.: Eur. J. Med. Chem., 34, 745 (1999), Kim, H., et al.: J. Pharm. Biomed. Anal., 27, 51 (2002), Santelli-Rouvier, C., et al.: Eur. J. Med. Chem., 39, 735 (2004),<br></p>Fórmula:C8H9NO4SForma y color:NeatPeso molecular:215.23Benzylhydrochlorothiazide
CAS:Producto controladoFórmula:C14H14ClN3O4S2Forma y color:NeatPeso molecular:387.86Hydroflumethiazide-13CD2
CAS:Producto controlado<p>Applications Labelled Hydroflumethiazide. Antihypertensive; diuretic.<br>References Piala, J.J., et al.: J. Pharmacol. Exp. Ther., 134, 273 (1961), Orzech, C.E., et al.: Anal. Profiles Drug Subs., 7, 297 (1978),<br></p>Fórmula:C713CH6D2F3N3O4S2Forma y color:NeatPeso molecular:334.30rac 1-Nitroso-2-methylindoline
CAS:Producto controladoFórmula:C9H10N2OForma y color:BrownPeso molecular:162.19N-Nitroso Furosemide ( >80%)
CAS:Fórmula:C12H10ClN3O6SPureza:>80%Forma y color:Light Orange To Dark OrangeMethyl 4-Hydroxy-2H-1,2-benzothiazine-3-carboxylate 1,1-Dioxide
CAS:Producto controlado<p>Impurity Piroxicam EP Impurity G<br>Applications Piroxicam impurity G.<br>References Lombardino, J., et al.: J. Med. Chem., 14, 1171 (1971), Turck, D., et al.: Clin. Pharmacol., 36, 79 (1996), Bihovsky, R., et al.: Bioorg. Med. Chem. Lett., 14, 1035 (2004),<br></p>Fórmula:C10H9NO5SForma y color:NeatPeso molecular:255.254-Amino-5-[(3,4,5-trimethoxyphenyl)methyl]-2(1H)-pyrimidinone
CAS:Producto controlado<p>Impurity USP Trimethoprim Related Compound A<br>Applications 6-Amino-5-[(3,4,5-trimethoxyphenyl)methyl]-2(1H)-pyrimidinone, is an impurity of Trimethoprim (T795615), an antibacterial agent.<br>References Popov, V. M., et al.: Bioorg. Med. Chem. Lett., 16, 4366 (2006); Brogden, R.N., et al.: Drugs, 23, 405 (1982);<br></p>Fórmula:C14H17N3O4Forma y color:WhitePeso molecular:291.30Glimepiride-d5
CAS:Producto controlado<p>Applications A sulfonylurea hypoglycemic agent. Used as an antidiabetic.<br>References Ratheiser, K., et al.: Arzneimittel-Forsch., 43, 856, (1993),<br></p>Fórmula:C24H29D5N4O5SForma y color:Off-WhitePeso molecular:495.65Dehydro Indapamide
CAS:Producto controlado<p>Impurity Indapamide USP Related Compound A/ Indapamide EP Impurity B<br>Applications A metabolite of Indapamide (M5). A dehydrogenation pathway by cytochromes P450. Indapamide USP Related Compound A<br>References Tamura A., et al.: Chem. Pharm. Bull., 38, 225 (1990), Harlow, G.R., et al.: J. Biol. Chem., 272, 5396 (1997), Ozden, T., et al.: Pharm. Pharmacol. Commun., 4, 397 (1998), Gruciani, G., et al.: J. Med. Chem., 48, 6970 (2005), Sun, H., et al.: Drug. Metab. Dispos., 37, 672 (2009),<br></p>Fórmula:C16H14ClN3O3SForma y color:White To Light BrownPeso molecular:363.823-Nitro-4-phenoxy-5-sulfamoylbenzoic Acid
CAS:<p>Impurity Bumetanide Impurity A<br>Applications 3-Nitro-4-phenoxy-5-sulfamoylbenzoic Acid is a compound related to Piretanide (P508700) and an intermediate in the production of Bumetanide, Bumetanide Impurity A (B689550).<br></p>Fórmula:C13H10N2O7SForma y color:NeatPeso molecular:338.29Ibuprofen Dimer
CAS:Producto controlado<p>Impurity Ibuprofen EP Impurity G<br>Applications Ibuprofen Dimer (Ibuprofen EP Impurity G) is a dimer impurity of Ibuprofen (I140000).<br></p>Fórmula:C26H32O4Forma y color:Light Orange ColourPeso molecular:408.53rac Ibuprofen-d3
CAS:Producto controlado<p>Applications Labelled Ibuprofen, a selective cyclooxygenase inhibitor (IC50=14.9uM). Inhibits PGH synthase-1 and PGH synthase-2 with comparable potency.<br>References Busson, M., et al.: J. Int. Med Res., 14, 53 (1986), Meade, E.A., et al.: J. Biol. Chem., 268, 6610 (1993), Davies, N.M., et al.: Clin. Pharmacokinet., 34, 101 (1998),<br></p>Fórmula:C132H3H15O2Forma y color:Off-WhitePeso molecular:209.30Bis(4-hydroxyphenyl) Sulfone
CAS:Producto controlado<p>Applications Bis(4-hydroxyphenyl) Sulfone is commonly used as a reactant in epoxy reactions and is also used as a latent thermal catalyst for epoxy resin.<br>References Fu, J.W., et al.: Adv. Mat. Rsch., 266, 1022 (2011); Li, J.X., et al.: Polymers. Adv. Tech., 23, 803 (2012);<br></p>Fórmula:C12H10O4SForma y color:WhitePeso molecular:250.274-[2-[(3-Ethyl-4-methyl-2-oxo-3-pyrrolin-1-yl)carboxamido]ethyl]benzenesulfonamide
CAS:<p>Impurity Glimepiride EP Impurity B/ USP Glimepiride Related Compound B<br>Applications 4-[2-[(3-Ethyl-4-methyl-2-oxo-3-pyrrolin-1-yl)carboxamido]ethyl]benzenesulfonamide (Glimepiride EP Impurity B) is an intermediate for the preparation of Glimepiride.<br></p>Fórmula:C16H21N3O4SForma y color:Off-WhitePeso molecular:351.42N,N-Dimethylnicotinamide-2-sulfonamide
CAS:Producto controlado<p>Applications N,N-Dimethylnicotinamide-2-sulfonamide (cas# 112006-75-4) is a compound useful in organic synthesis.<br></p>Fórmula:C8H11N3O3SForma y color:NeatPeso molecular:229.262-Amino-5-chlorobenzenesulfonamide
CAS:Producto controlado<p>Applications 2-Amino-5-chlorobenzenesulfonamide is a metabolite of IDRA-21 (I232500), which inhibits AMPA receptor desensitization and enhances cognition by a related mechanism. IDRA-21 is more able to cross the blood-brain barrier than Cyclothiazide (C988960).<br>References Cannazza, G., et. al.: Bioorg. Med. Chem. Lett., 19, 1254 (2009); Zivkovic, et al.: J. Pharmacol. Exp. Ther., 272, 300 (1995); Dingledine, R., et al.: Pharmacol. Rev., 51, 7 (1999); Sun, Y., et al.: Nature, 417, 245 (2002); Thomsen, R., et al.: J. Med. Chem., 49, 3315 (2006)<br></p>Fórmula:C6H7ClN2O2SForma y color:NeatPeso molecular:206.65
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