Sulfonamidas y derivados
Las sulfonamidas son compuestos que contienen un grupo funcional sulfonamida (-SO₂NH₂), en el que un átomo de azufre está unido a un grupo amino. Fueron de los primeros antibióticos sintéticos utilizados en medicina, inhibiendo la síntesis de ácido fólico en bacterias, lo que les confiere propiedades antimicrobianas. Se utilizan principalmente para tratar infecciones bacterianas, aunque hoy en día su uso se ha visto reducido debido a la resistencia antimicrobiana. Además de su uso en antibióticos, las sulfonamidas también tienen aplicaciones en el tratamiento de enfermedades como la malaria y enfermedades inflamatorias intestinales.
En CymitQuimica ofrecemos sulfonamidas y sus derivados con alto grado de pureza para investigación en microbiología y desarrollo farmacéutico.
Se han encontrado 2592 productos de "Sulfonamidas y derivados"
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5-(Acetylamino)-1,3,4-thiadiazole-2-sulfonic Acid Potassium Salt
CAS:Producto controlado<p>Impurity Acetazolamide EP Impurity E<br>Applications 5-(Acetylamino)-1,3,4-thiadiazole-2-sulfonic Acid is an impurity of Acetazolamide (A161500). (Acetazolamide EP impurity E)<br>References Zarghi, A., et al.: J. Pharm. Biomed. Anal., 28, 169 (2002), Subbarao, D., et al.: J. Chromatogr., 67, 841 (2008),<br></p>Fórmula:C4H4KN3O4S2Forma y color:NeatPeso molecular:261.32p-Ethylhydratropic Acid
CAS:<p>Impurity Ibuprofen EP Impurity N<br>Applications p-Ethylhydratropic Acid (Ibuprofen EP Impurity N) is a phenylacetic acid with potential antiinflammatory activities. p-Ethylhydratropic Acid is an impurity of Ibuprofen (I140000).<br></p>Fórmula:C11H14O2Forma y color:WhitePeso molecular:178.233-(4-Isobutylphenyl)propanoic Acid
CAS:Producto controlado<p>Impurity Ibuprofen EP Impurity F<br>Applications 3-(4-Isobutylphenyl)propanoic acid (Ibuprofen EP Impurity F) is an impurity of Ibuprofen (I140000). Ibuprofen impurity F as per EP.<br>References Haikala, V., et al.: J. Pharm. Sci., 80, 456 (1991), Zhao, J., et al.: Anal. Chem., 72, 302 (2000), Kucera, R., et al.: J. Pharm. Biomed. Anal., 38, 609 (2005),<br></p>Fórmula:C13H18O2Forma y color:NeatPeso molecular:206.285-Oxomefruside
CAS:<p>Applications 5-Oxomefruside is a lactone metabolite and impurity of the drug Mefruside (M205150).<br>References Puetter, J., et al.: Biochimica et Biophysica Acta, General Subjects, 286, 186 (1972).<br></p>Fórmula:C13H17ClN2O6S2Forma y color:NeatPeso molecular:396.87Bumetanide 3-(Butyl(nitroso)amino)
CAS:Producto controlado<p>Impurity Bumetanide Impurity<br>Applications Bumetanide 3-(Butyl(nitroso)amino) is an impurity of Bumetanide(B689550). Bumetanide is a diuretic.<br>References Ward, A., et al.: Drugs, 28, 426 (1984), Gradeen, C.Y, et al.: J. Anal. Toxicol., 14, 123 (1990), Tata, P.N.V., et al.: Anal. Profiles Drug Subs. Excip., 22, 107 (1993),<br></p>Fórmula:C17H19N3O6SForma y color:NeatPeso molecular:393.41(±)-Ibuprofen Methyl Ester
CAS:Producto controlado<p>Applications (±)-Ibuprofen Methyl Ester is a phototoxic, photoproduct of Ibuprofen (I140000), a selective cyclooxygenase inhibitor (IC50=14.9uM). Inhibits PGH synthase-1 and PGH synthase-2 with comparable potency. Ibuprofen is also used as an anti-inflammatory drug.<br>References Miranda, M.A., et. al.: Toxicol. In Vitro, 5, 451 (1991); Busson, M., et al.: J. Int. Med Res., 14, 53 (1986); Meade, E.A., et al.: J. Biol. Chem., 268, 6610 (1993); Davies, N.M., et al.: Clin. Pharmacokinet., 34, 101 (1998)<br></p>Fórmula:C14H20O2Forma y color:ColourlessPeso molecular:220.315-Aminosalicylic Acid-13C6 Hydrochloride (Mesalazine-13C6 Hydrochloride)
CAS:Producto controladoFórmula:C13C6H7NO3·HClForma y color:NeatPeso molecular:195.55Quininone
CAS:<p>Applications Quininone has been shown to have antimalarial activity in mice. Quininone has been shown to aid the binding of drug-induced antibodies to human platelets.<br>References Klayman, D.L., et. al.: J. Med. Chem., 16, 1042 (1973); Christie, D.J., et. al.: J. Lab. Clin. Med., 104, 730 (1984)<br></p>Fórmula:C20H22N2O2Forma y color:White To Light BeigePeso molecular:322.40Acetaminophen (1 mg/mL in Methanol)
CAS:Producto controladoFórmula:C8H9NO2Forma y color:Single SolutionPeso molecular:151.16Aceclofenac Ethyl Ester
CAS:Producto controlado<p>Impurity Aceclofenac EP Impurity E<br>Applications Aceclofenac Ethyl Ester is a 2-[(2,6-dichlorophenyl)amino]phenylacetoxyacetyl derivative used as an anti-inflammmatory and analgesic agent. Aceclofenac EP Impurity E.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Yscla, A., et al.: Drugs Exp. Clin. Res., 14, 491 (1988), Ballesteros, R., et al.: Clin. Trials J., 27, 12 (1990)<br></p>Fórmula:C18H17Cl2NO4Forma y color:White To Light YellowPeso molecular:382.246-Hydroxy Etodolac
CAS:Producto controlado<p>Applications 6-Hydroxy Etodolac is an Etodolac (E933100) metabolite.<br>References Humber, L., et al.: J. Med. Chem., 32, 2582 (1989), Koupai-Abyazani, M., et al.: J. Anal. Toxicol., 23, 200 (1999),<br></p>Fórmula:C17H21NO4Forma y color:NeatPeso molecular:303.353-(N-Acetyl-L-cystein-S-yl) Acetaminophen
CAS:Producto controlado<p>Stability Very Hygroscopic<br>Applications Paracetamol Mercapturate is a metabolite of Acetaminophen (A161220) (1,2). Acetaminophen is a widely used analgesic and antipyretic drug. It can also be used in biological study of urinary antihypertensive drug metabolite screening using molecular networking coupled to high-resolution mass spectrometry fragmentation.<br>References (1) Trettin, A., et al.: J. Chromatogr. B., 963, 105 (2014) (2) Pickering, G., et al.: Clin. Pharmacol. Ther., 90, 707 (2011)<br></p>Fórmula:C13H16N2O5SForma y color:NeatPeso molecular:312.342,4-Disulfamyl-5-trifluoromethylaniline
CAS:Fórmula:C7H8F3N3O4S2Forma y color:White To Off-WhitePeso molecular:319.28Oxyclozanide
CAS:<p>Applications Oxyclozanide, an anthelmintic drug displays strong in vivo and vitro activity against methicillin resistant S. aureus and Gram-positive bacteria Enterococcus faecium.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Rajamuthiah, R., et al.: PLOS ONE, 10, 1-19 (2015)<br></p>Fórmula:C13H6Cl5NO3Forma y color:NeatPeso molecular:401.464-Isobutylbenzoic Acid
CAS:<p>Applications 4-Isobutylbenzoic Acid is used in the studies for the identification of the degradation products and potential impurities in Ibuprofen. 4-Isobutylbenzoic Acid is also applied in the determination of related substances in dexibuprofen using HPLC.<br>References Dondoni, A., et al.: Farmaco, Edizione Pratica, 41, 237 (1986); Xie, L., et al.: Zhongguo Yaoshi, 19, 1088 (2016)<br></p>Fórmula:C11H14O2Forma y color:NeatPeso molecular:178.23(-)-(3S)-3-Hydroxy Quinine
CAS:Producto controladoFórmula:C20H24N2O3Forma y color:NeatPeso molecular:340.42Triflusulfuron-methyl
CAS:Producto controlado<p>Applications Triflusulfuron-methyl, is a widely used sulfonylurea herbicide.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Song, N., et al.: Huanjing Kexue, 33, 4400 (2012);<br></p>Fórmula:C17H19F3N6O6SForma y color:WhitePeso molecular:492.43Acetaminophen Dimer-d6
CAS:Producto controlado<p>Applications Acetaminophen Dimer-d6 is deuterium labeled Acetaminophen Dimer (A161235). Acetaminophen Dimer is an oxidatively couple dimer of Acetaminaphen (A161220), an analgesic and antipyretic agent used as a pain reliever to treat headache, muscle aches, and arthritis (1). Acetaminophen Dimer along with other p-acetamidophenol analogs were used to determine peroxidase activities (2,3).<br>References (1) McGill, M. R. and Jaeschke, H. Pharm Res. 30, 2174 (2013)(2) Potter, D.W. et al.: Mol. Pharmacol., 29, 155 (1986)(3) Shiga, M. et al.: Anal. Sci., 11, 195 (1995)<br></p>Fórmula:C16H10D6N2O4Forma y color:NeatPeso molecular:306.35O,O-Di-2-Naphthalenyl Ester Carbonothioic Acid
CAS:Fórmula:C21H14O2SForma y color:NeatPeso molecular:330.4
