Terpenoides y derivados

<p>Applications The natural isomer of the abscission-accelerating plant hormone.<br>References Krochko, J.E., et al.: Plant Physiol., 118, 849 (1998), Jacobsen, J.V., et al.: Psysiol. Plant., 115, 428 (2002),<br></p>

<p>Applications Artemether- 13C, d3, is the labeled analogue of Artemether (A777400), which is a derivative of Artemisinin (A777500). Antimalarial, used to treat strains of malaria which are multi-drug resistant.<br>References Hombhanje, F., et al.: Pharma., 3, 3581 (2010), Michael, O., et al.: Malaria J., 9, 335 (2010), Cesar, I., et al.: J. Pharm. Biomed. Anal., 54, 114 (2011),<br></p>

<p>Stability Light and Temperature Sensitive<br>Applications A metabolite of Retinoic acid.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Hoyos, B., et al.: J. Exp. Med.,192, 835 ( 2000), Braungart, E., et al.: J. Invest. Dermatol.,116, 778 (2001), Fray, M., et al.: J. Med. Chem., 46, 3514 (2003), Ha, M., et al.: Exp. Dermatol., et al.: 13, 543 (2004),<br></p>

<p>Applications Retinoic Acid 3,3-Dimethyl-2-oxobutyl Ester, is a Retinoic Acid derivative that has shown to be used for treatment of dermatological disorders.<br>References Mealy, N. E., et al.: Drugs of the Future, Vol.29, P:393-436 (2004);<br></p>

<p>Applications Cycloartenol is a triterpenoid used in eukaryotic steroid biosynthesis.<br>References Bode, H., et al.: Mol. Microbiol., 47, 471 (2003); Schwartz, H., et al.: J. Food Comp. Anal., 21, 152 (2007);<br></p>

<p>Stability Hygroscopic<br>Applications 20(S)-Ginsenoside Rg2 is used as an aldose reductase inhibitor and my exert anti-inflammatory and immunomodulatory activity. It exists as a bioactive metabolite of the ginsenoside component of Panax ginseng.<br>References Cho, K. et al.: Biomol. Ther., 22, 55 (2014); Fatmawati, S. et al.: Bioorg. Med. Chem. Lett., 24, 4407 (2014);<br></p>

<p>Impurity Paclitaxel - Impurity N<br>Applications A precursor to Paclitaxel, a neoplasm inhibitor to ovarian and breast cancers found in Taxus species. Paclitaxel - Impurity N.<br>References Katkovcinova, Z., et al.: J. Biosci., 63, 721 (2008), Tian, J., et al.: J. Pharm. Sci., 97, 3100 (2008), Miao, Z., et al.: App. Biochem. Microbiol., 45, 81 (2009),<br></p>

<p>Applications Artemisinin (A777500) is an effective antimalarial agent used to treat malaria. Artemisinic Aldehyde is converted into dihydroartemisinic aldehyde by Artemisinic aldehyde Δ11 (13) reductase (DBR2), which is involved in the biosynthetic pathway of artemisinin in Artemisia annua L.<br>References Yuan, Y., et al.: Biotechnol Appl Biochem 62, 17 (2015); Arjen, M. D., et al.: N Engl J Med 361, 455 (2009)<br></p>

<p>Applications Gibberellin A4 is a plant growth hormone that regulates growth and differentiation of plant cells for elongation, germination and enzyme induction.<br>References Zhang, R., et al.: Trees., 26, 1113 (2012); Sinska, I., et al.: Plant. Sci. Lett., 9, 163 (1977);<br></p>

<p>Impurity Paclitaxel - Impurity K<br>Applications Protected Paclitaxel. Paclitaxel - Impurity K.<br>References Kerns, E., et al.: J. Nat. Products, 57, 1391 (1994), Golik, J., et al.: Bioorg. Med. Chem. Lett., 6, 1837 (1996),<br></p>

<p>Applications Dehydroabietic Acid is a resin acid found commonly in rosin. Dehydroabietic Acid is used in rosin-type nucleating agent for polypropylene (PP). Dehydroabietic Acid is used commonly in the synthesis of surfactants, antioxidants and chiral catalysts.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Stricker, J.: Plaste Kautsch., 16, 481 (1969); Cui, G. et al.: Jing. Yu Zhuan. Huax., 14, 6 (2006); Wang, H. et al.: J. Appl. Polym. Sci., 89, 2137 (2003);<br></p>

<p>Applications Nordihydrocapsaicin is a capsaicinoid and analog and congener of capsaicin in chili peppers.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Iwai, K., et al.: Agri. Biol. Chem., 43, 2493 (1979); Kozukue, N., et al.: J. Agr. Food Chem., 53, 9172 (2005)<br></p>

<p>Applications 13-cis-Fenretinide, is an isomer of all-trans-Fenretinide (F250000), which is a synthetic analog of Vitamin A.<br>References Marth, C., et al.:J. Nat. Cancer Inst., 75, 871 (1985), Delia, D., et al.: Cancer Res., 53, 6036 (1993), Costa., A., et al.: Cancer Res., 54, Suppl., 2032s (1994), Decensi., A., et al.: Eur. J. Cancer Prev., 3, 377 (1994)<br></p>

<p>Applications Gibberellin A1 is a derivative of Gibberellic Acid (G377450), a hormone that is found in plants which promotes the growth and elongation of cells. Gibberellic acid acts as a plant growth regulator on account of its physiological and morphological effects in extremely low concentrations.<br>References Bayle, J. et al.: Chem. Biol., 13, 99 (2006); Ihara, S. et al.: J. Cell Sci., 119, 500 (2006); Suh, B. et al.: Science, 314, 1454 (2006); Rinaudo, K. et al.: Nat. Biotechnol., 25, 795 (2007);<br></p>

<p>Applications An analogue of Artemisinin, an antimalarial agent.<br>References Mitchell, T., et al.: Clin. Microbiol. Rev., 8, 515 (1995), Posner, G., et al.: Bioorg. Med. Chem., 5, 1257 (1997) , Li, X., et al.: J. Nat. Prod., et al.: 62, 674 (1999),<br></p>

<p>Stability Light Sensitive<br>Applications A deuterated metabolite of all-trans-Retinoic Acid, a ligand for both the retinoic acid receptor (RAR) and the retinoid X receptor (RXR).<br>References Andreola, F., et al.: J. Biol. Chem., 279, 3434 (2004), Armstrong, J., et al.: Biochem. Pharmacol., 69, 1299 (2005), Njar, V., et al.: Bioorg. Med. Chem., 14, 4323 (2006), Veal, G., et al.: Br. J. Cancer, 96, 424 (2007),<br></p>

<p>Stability Light Sensitive<br>Applications β-Cyclocitral, Technical Grade (cas# 432-25-7) is a compound useful in organic synthesis. It has been in a biological study involving the analysis of aroma components with SSR markers in flue-cured tobacco.<br>References Wang, G. P., et al.: Zhiwu Yichuan Ziyuan Xuebao, 17, 671 (2016)<br></p>

<p>Applications Cyclopentyl chloride (cas# 930-28-9) is a useful research chemical.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications Gamma Oryzanol is a mixture of 6 substances derived from rice bran oil, including sterols and ferulic acid, called Cycloartanyl Ferulate or Triterpene alcohol ferulate. It has been approved in Japan for several conditions, including menopausal symptoms, mild anxiety, stomach upset, and high cholesterol. In the US, it is widely used as a sports supplement, as well as for reducing cholesterol.Gamma Oryzanol is widely used as a food additive, pharmaceutical material. In cosmetic area, the application to creams and sunscreens exploiting its skin age resistor function and ultraviolet absorbing effect.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Somogyi, M., et al.: J. Biol. Chem., 195, 19 (1952), Wiseman, H., et al.: Biochemical. J., 313, 17 (1996), Banchuen, J., et al.: J. Agricul. Sci., 2009, 42, 191 (2009),<br></p>

<p>Applications De-Boc Cabazitaxel is an impurity of Cabazitaxel (C046500) which is a novel semi-synthetic taxane with antitumor activity used for the treatment of castration-resistant prostate cancer.<br>References Agarwal, N. et al.: Fut. Oncol., 7, 15 (2011); Mita, A. et al.: Clin. Cancer Res., 15, 723 (2009); Figg, W.D. et al.: Cancer Biol. Ther., 10, 1233 (2010);<br></p>

<p>Stability Light Sensitive<br>Applications A synthetic retinoid which is the major metabolite of Etretinate (E938000).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Sato, T., et al.: J. Med. Chem., 51, 7705 (2008), Liu, X., et al.: Cancer Chemother. Pharmacol., 63, 167 (2008),<br></p>

<p>Stability Hygroscopic<br>Applications A major bioactive component of panax ginseng that promotes neurotransmitter release by modulating phosphorylation of synapsins through a cAMP-dependent protein kinase pathway. It has been reported to display immunostimulatory and anticancer effects.<br>References Xue, J. et al.: Brain Res., 1106, 91 (2006); Kim, B. et al.: J. Ginseng Res., 33, 330 (2009); Li, B. et al.: Cancer Lett., 289, 62 (2010);<br></p>

<p>Applications Menthyl Acetate is a component of essential oils extracted from natural sources.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Adaszynska, Michalina, et al.: Zywnosc, 20(2), 116-125 (2013);Hashimoto, Gabriela S., et al.: Aquaculture, 450, 182-186 (2016);Mazzucotelli, Maria, et al.: J. of Chrom. A, 1583, 124-135 (2019)<br></p>

<p>Applications 4-Methylbenzylidene camphor (4-MBC) is an organic camphor derivative that is used in the cosmetic industry for its ability to protect the skin against UV, specifically UV B radiation. 4-MBC a UV-B ray filter, is an endocrine disruptors (ED).<br>References Schlumpf, M., et al.: Toxicology, 199, 109 (2004), Durrer, S., et al.: Endocrinology, 146, 2130 (2005), Seidlova-Wuttke, D., et al.: Toxicol. Appl. Pharmacol., 214, 1 (2006), Maerkel, K., et al.: Toxicol. Appl. Pharmacol., 218, 152 (2007),<br></p>

<p>Applications Movento is a synergistic insecticide. Useful in cannabis testing kits as a component of pesticide mixes (P698240).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Byrne, F., et al.: Crop. Prot., 25, 831 (2006), Kanrar, B., et al.: Bull Environ. Contam. Toxicol., 77, 631 (2006), Venkateswarlu, P., et al.: Food Chem., 105, 1760 (2007), Khay, S., et al.: Biomed. Chromatogr., 22, 581 (2008),<br></p>

<p>Stability Light Sensitive, Temperature Sensitive<br>Applications A metabolite of vitamin A (Retinol) (R252000).<br>References Allo, S., et al.: J. Biol. Chem., 266, 22003 (1991), Brancolini, C., et al.: J. Cell Biol., 139, 759 (1997), Bubb, M., et al.: J. Biol .Chem., 269, 14869 (1994),<br></p>

<p>Applications Campesteryl Ferulate is a component of γ-​oryzanol with antioxidant activities.<br>References Xu, Z., et al.: J. Agric. Food Chem., 49, 2077 (2001);<br></p>

<p>Stability Hygroscopic<br>Applications β-Tocopherol (Racemic Mixture) is one of the naturally occurring forms of Vitamin E. Is biologically less active than α-Tocopherol. This is the racemic mixture of all stereoisomers.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Bianchi, G., et al.: Eur. J. Lipid Sci. Technology, 105, 229 (2003), Sakouhi, F., et al.: Food Chem., 108, 833 (2008),<br></p>

<p>Applications Ginsenoside Rh4 possesses inhibitory and antifungal activity.<br>References Xue, P., et al: RSC Adv., 7, 10939-10946 (2017)<br></p>

<p>Applications Triptolide is a diterpenoid triepoxide with immunosuppressant and antitumor properties.<br>References Hikim, S., et al.: J. Androl., 21, 431 (2000), Chang, W.-T., et al.: J. Biol. Chem., 276, 222 (2001), Kiviharju, T.M., et al.: Clin. Cancer Res., 8, 2666 (2002), Leuenroth, S.J., et al.: Chem. Biol., 12, 1259 (2005),<br></p>

<p>Stability Hygroscopic<br>Applications Cantharidin is a well known natural compound produced by beetles of the Meloidae and Oedemeridae families. Insecticidal toxin. Apoptosis inducer in human H460 human lung cancer cells.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Khan, R. et al.: GMR. Gen. Mol. Res., 12, 4393 (2013); Hsia, T. et al.: Int. J. Onc., 45, 245 (2014);<br></p>

<p>Applications β-Selinene is a natural product found in essential oils from variety of plants. It is a functional antioxidant with antiradical and antimicrobial properties.<br>References Sacchetti, G., et al.: Food Chem., 91, 621 (2005); Bozin, B., et al.: J. Agric. Food Chem., 54, 1822 (2006);<br></p>

<p>Applications Docetaxel is an antimitotic Taxol analog antibiotic.<br></p>

<p>Applications Gibberellin A7 is an plant hormone that was isolated from culture filtrates of the fungus Gibberella fujikuroi. Gibberellin A7 was shown to promote the growth and elongation of cells.<br>References Cross, B.E., et al.: Tetrahedron., 8, 451 (1962); Meijon, M., et al.: J. Plant. Growth. Regulat., 30, 74 (2011); Ward, D.A., et al.: Phytochem., 71, 2010 (2010);<br></p>

<p>Applications 3-Phenoxybenzoic Acid, can be used in the preparation of widely used insecticides, such as Permethrin (P288500). which is a synthetic chemical, used as an insecticide, acaricide, and insect repellent.<br>References Elliott, M., et al.: Nature, 246, 169 (1973); Zheng, M., et al.: Zhongguo Ertong Baojian Zazhi, 20, 409 (2012);<br></p>

<p>Applications Spirotetramat Metabolite BYI08330-​cis-​enol is a metabolite and can be used as analyte in analytical and biological studies for multi-residue method for determination of pesticides and pesticide metabolites in honeybees by liquid and gas chromatography coupled with tandem mass spectrometry, used to investigate honeybee poisoning incidents.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Kiljanek, T., et al.: J Chromatgr A, 1435, 100 (2016)<br></p>

<p>Stability Hygroscopic<br>Applications Midostaurin-13C6 is the labelled analogue of Midostaurin (M343760), a compound shown to possess antiproliferative characteristics via inhibition of protein kinase C, kinase insert domain receptor, and c-kit.<br>References Tahtouh, T., et al.: J. Med. Chem., 55, 9312 (2012); Pedeboscq, S., et al.: PLoS. One., 7, 36811 (2012);<br></p>

<p>Applications Olivetol-d9 is a precursor in various syntheses of labelled tetrahydrocannabinols.<br>References Kumano, T., et al.: Bioorg. Med. Chem., 16, 8117 (2008), Appendino, G., et al.: J. Nat. Prod., 71, 1427 (2008), Sampietro, D., et al.: Food Chem., 115, 1170 (2009),<br></p>

<p>Applications A metabolite of Artemether (A777400) and derivative of the antimalarial drug Artemisinin (A777500). Studies suggest that it may display neurotoxicity in animals due to its interaction with iron.<br>References Smith, S.L. et al.: Neurotoxicology, 19, 557 (1998); Blum, W. et al.: J. Chrom. B Biomed. Sci. Appl., 710, 101 (1998);<br></p>

<p>Applications Family of bioactive terpenes treating cardiovascular and cerebrovascular diseases. Specific platelet activating factor (PAF) antagonists.<br>References Korth, R., et al.: Eur. J. Pharmacol., 152, 101 (1988), Braquet, P., et al.: Med. Res. Rev., 11, 295 (1991), van Beek, T.A., et al.: Bioorg. Med. Chem., 13, 5001 (2005)<br></p>

<p>Applications ISOBORNYL ACRYLATE (cas# 5888-33-5) is a useful research chemical.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Neophytadiene is a diterpene compound extracted from Turbinaria ornate, with anti-inflammatory, anticonvulsant, antioxidant, and cardioprotective effects.</p>

<p>Stability Hygroscopic<br>Applications Ginsenoside Rg1 protects against arthitis through osteoclast differentiation inhibition. Anti-tumor agent, inhibits the NF-kB-dependant MMP-expression in PMA (phorbol myristate acetate)-induced tumor cell invasion.<br>References Gu, Y. et al.: Med. Infl., 305071/14. (2014); Li, L. et al. Onc. Rep., 32, 1779 (2014);<br></p>

<p>Stability Light Sensitive<br>Applications α-Tocopherol is the most bioactive of the naturally occurring forms of Vitamin E. Richest sources are green vegetables, grains, and oils, particularly palm, safflower and sunflower oils.<br>References Bianchi, G., et al.: Eur. J. Lipid Sci. Technology, 105, 229 (2003), Sakouhi, F., et al.: Food Chem., 108, 833 (2008),<br></p>

<p>Applications Artemether (A777400) impurity. Artemisinin impurity<br>References Pandey, A., et al.: J. Biol. Chem., 274, 19383 (1999), Kremsner, P., et al.: Lancet, 364, 285 (2004),<br></p>

<p>Stability Light Sensitive, Temperature Sensitive<br>Applications Enzyme inhibitor.This product contains up 15% hexanes and up to 5% of the analogous dimer by NMR.<br>References Rowell, C.A., et al.: J. Biol. Chem., 272, 14093 (1997), Sebti, S.M., et al.: Pharmacol. Ther., 74, 103 (1997), Sun, J., et al.: Cancer Res., 59, 1919 (1999),<br></p>

<p>Applications Octocrylene is a UV-A and UV-B filter used in sunscreen and topical drug formulations.<br>References Lacatusu, I. et al.: Chem. Eng. J., 246, 311 (2014); Allen, J. et al.: Chem. Res. Tox., 9, 605 (1996);<br></p>

<p>Applications (2R,3S)-N-Benzoyl-3-phenylisoserine ethyl ester is an intermediate in the preparation of potent anticancer drug Paclitaxel (P132500) used to study the location of the binding sites. (2R,3S)-N-Benzoyl-3-phenylisoserine ethyl ester shows cytotoxic, antiviral and immunomodulatory activity.<br>References Paal, K. et al.: Bioorg. Med. Chem., 15, 1323 (2007); Krawczyk, E. et al.: J. Pharm. Pharmacol., 57, 791 (2005);<br></p>

<p>Stability Hygroscopic<br>Applications Deoxydihydroartemisinin is used in biological studies antimalarial and possible antitumor effects via oxidative stress, modulated by hypoxia, in microendothelial cells.<br>References D’alessandro, S., et al.: Biochem. Pharm., 82, 476 (2011);<br></p>

<p>Applications Amorphadiene is a sesquiterpene synthesized via the cyclization of farnesyl pyrophosphate and a precursor in the biosynthesis of Artemisinin (A777500), which is an effective antimalarial agent used to treat malaria. Genetically modified Saccharomyces cerevisiae can be utilized as an alternative semisynthetic strategy to produce artemisinin from amorphadiene.<br>References Wallaart, T. E., et al.: Planta 212, 460 (2001); Westfall, P. J. et al.: Proc. Natl. Acad. Sci. USA 109, E111 (2012); Shiba, Y., et al.: Metab. Eng 9, 160 (2007).<br></p>

<p>Applications DL-Camphene, is a minor constituent of many essential oils such as turpentine, cypress oil, camphor oil, citronella oil (C525020), neroli, ginger oil, and valerian. It can also be used in fragrances and as a food additive for flavoring.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Perino-Issartier, S., et al.: J. Chromatography A, 1305 (2013); Zhang, L., et al.; Shizhen Guoyi Guoyao, 23, 3061 (2012);<br></p>

<p>Applications Plant hormone; natural steroid containing a seven-membered B-ring lactone, that promotes both cell elongation and cell devision. Over ten brossinosteroids have been isolated and characterized from sources such as pollen, seedling, leaf. Used as plant growth regulator.<br>References Grove, M.D., et al.: Nature, 281, 216 (1979), Schlagnhaufer, C., et al.: Physiol. Plant., 60, 347 (1984), Wada, K., et al.: Agric. Biol. Chem., 48, 719 (1984),<br></p>

<p>Applications A precursor to Paclitaxel.<br></p>

<p>Stability Light Sensitive, Temperature Sensitive<br>Applications An endogenous retinoic acid isomer, which is capable of binding to both retinoic acid receptors (RAR) and retinoid X receptors (RXR). A biologically active ligand for members of the RAR and RXR subfamilies, implying that it may play a critical role in regulating retinoid-responsive pathways.<br>References Heyman, R.A., et al.: Cell, 68, 397 (1992), Levin, A.A., et al.: Nature, 355, 359 (1992), Allenby, G., et al.: Proc. Natl. Acad. Sci. U.S.A., 90, 30 (1993)<br></p>

<p>Applications Squalene is a natural triterpene that plays an important role in the synthesis of cholesterol, steroid hormones, and vitamin D in the human body. Squalene is commonly used as a biochemical precursor in the preparation of steroids. Squalene is also a natural moisturizer with low acute toxicity and is not significant human skin irritants or sensitizers.<br>References Smith, T.J.: Exp. Op. Invest. Drugs, 9, 1841 (2000); Bloch, K.E.: Crit. Rev. Biochem. Mol. Biol., 14, 47 (1983); Huang, Z.R. et al.: Molecules, 14, 540 (2009);<br></p>

<p>Stability Light Sensitive<br>Applications Carvone is useful for the treatment of various metabolic disorders and GI related disorders.<br>References Shabi, M. M., et al.: Res. J. Pharm. Biol. Chem. Sci., 8, 328 (2017)<br></p>

<p>Applications 3-(2,2-Dichloroethenyl)-2,2-dimethylcyclopropanecarboxylic Acid is a reagent used in the preparation of hapten and immunogen for the production of polyclonal antibodies, specific to Cypermethrin (C989000).<br>References Lee, N. et al.: J. Agri. Food Chem., 46, 520 (1998); Hongsibsong, S. et al.: Int. J. Agri. Biol., 14, 246 (2012);<br></p>

<p>Applications 7-Methyl Docetaxel is a metabolite of Docetaxel (D494420), a microtubule inhibitor that has the potential to be used in treating hormone refractory prostate cancer.<br>References Figg, W., et al.: Semin. Oncol., 28, 62 (2001); Kort, A., et al.: J. Chromatogr. B, 925, 117 (2013)<br></p>

<p>Applications O-Desmethyl Midostaurin-13C6 is the labelled analogue of O-Desmethyl Midostaurin (D291400), a metabolite of Midostaurin (M343760), a compound shown to possess antiproliferative characteristics via inhibition of protein kinase C, kinase insert domain receptor, and c-kit.<br>References Tahtouh, T., et al.: J. Med. Chem., 55, 9312 (2012); Pedeboscq, S., et al.: PLoS. One., 7, 36811 (2012);<br></p>

<p>Applications 7α-Hydroxyfrullanolide is a natural product extracted from the aerial parts of Sphaeranthus indicus. 7α-Hydroxyfrullanolide has cytotoxic and antimalarial effects. It can also inhibit migratory, proliferative activity and pro-inflammatory cytokine production in keratinocytes and immune cells.<br>References Sangsopha, Watchara, et al.: Phytochemistry Letters, 17, 278-281 (2016); Fonseca, Lyle C., et al.: Euro. J. of Pharmaco., 644(1-3), 220-229 (2010); Chakrabarti, Debarshi, et al.: Pharmaco. &amp; Pharm., 3(2), 178-194 (2012)<br></p>

<p>Stability Light Sensitive<br>Applications One of the naturally occurring forms of Vitamin E. Most abundant Tocopherol in soybean and corn oils.<br>References Emerson, et al.: Science, 83, 421 (1936), Bieri, J.G., et al.: J. Nutr., 104, 850 (1974), Jiang, Q., et al.: Am. J. Clin. Nutr., 74, 714 (2001),<br></p>

<p>Applications Artemisitene, the oxidized form of Artemisinin (A777500), exists as a minor constituent in an American variant of Artemisia annua. Artemisinin precursors are the important basic substances for biosynthesis of Artemisinin, including Artemisinic acid, Artemisinin B, Artemisitene, etc. An antimalarial agent.<br>References Li, Y., et al.: Curr. Med. Chem., 10, 2197 (2003), Marrero-Ponce, Y., et al.: Bioorg. Med. Chem., 13, 1293 (2005), McMichael, A., et al.: Lancet, 367, 859 (2006),<br></p>

<p>Applications (3R,4R,4aS,7R,8S,8aR)-Hexahydro-3-hydroxy-4,7-dimethyl-8-(3-oxobutyl)-1,2-benzodioxin-8a(3H)-carboxaldehyde is an impurity of Artesunate (A777800).<br>References Baker, J.K., et al.: Pharmaceut. Res., 10, 662 (1993),<br></p>

<p>Applications Nerolidol (cas# 40716-66-3) is a terpene standard found in cannabis.<br></p>