Monosacáridos

Inhibitor of O-GlcNAcase

Inositol is a member of the B-vitamin family and is classified as a sugar alcohol. It has a structural similarity to glucose and can be synthesized by plants, bacteria, and mammals. Inositol is found in high concentrations in the brain and liver. Inositol has been shown to inhibit guanine nucleotide-binding proteins (G proteins) and ryanodine receptor channels in HL-60 cells. It also inhibits cancer cell proliferation and suppresses ovarian activity. Inositol appears to work by binding to the inositol-1,4,5-trisphosphate receptor on the surface of cells, thereby inhibiting intracellular calcium release from its storage site within the endoplasmic reticulum. The effects of inositol are mediated by dinucleotide phosphate or p-nitrophenyl phosphate.

2,3,4-Tri-O-benzyl-L-rhamnopyranose is a chemical compound that belongs to the family of carbohydrates known as rhamnopyranoses. It is a derivative of L-rhamnose, which is a naturally occurring aldohexose sugar. The compound is often used as a glycosyl donor in the synthesis of oligosaccharides and glycoconjugates. The three benzyl groups in the molecule provide protection for the hydroxyl groups, allowing for selective deprotection and glycosylation. 2,3,4-Tri-O-benzyl-L-rhamnopyranose is also used as a precursor in the synthesis of various natural products.

2,3,5-Tri-O-benzyl-b-D-ribofuranose is a synthetic monosaccharide that is used in the synthesis of complex carbohydrates such as glycosylation and polysaccharides. One use for this chemical is to modify the sugar moiety with methyl groups, yielding 2,3,5-tri-O-methyl b-D-ribofuranose. This modification helps prevent the sugar from being metabolized by enzymes in the body. The chemical can also be fluorinated to yield 2,3,5-trifluoro b-D-ribofuranose.

D-ido-Heptono-1,4-lactone is a glycosylation product of heptose with d-ido-D-glucofuranose and is a synthetic sugar. It has an Oligosaccharide, sugar, Synthetic, Fluorination, Custom synthesis, Methylation, Monosaccharide, Polysaccharide, saccharide Click modification. It has CAS No., Modification.

L-Talose is a type of sugar that is found in plants and animals. It is a stereoselective, synthetic carbohydrate with the chemical formula C12H24O11. L-Talose has an anhydrous dextrose equivalent (DE) of 180. L-Talose is synthesized from D-glucal and D-talonol by a recombinant protein. The immobilization process has been shown to be successful for the production of L-talose as it prevents the loss of product due to adsorption on the surface of the reactor. Molecular modeling was used to determine that L-talose binds to carbonyl groups more strongly than other types of molecules. Anhydrous dextrose was shown to be an effective acceptor for L-talose because it reacts with hydroxyl groups at room temperature and pressure conditions. The nmr spectra show that the hydroxyl group interacts with hydrogen bonding and coordinate covalent bonding

2,3,4,6-Tetra-O-benzyl-D-glucopyranose is a selectively protected intermediate, where the anomeric 1-O-hydroxyl group is free. This hemiacetal has been used successfully as an intermediate for glucosylation couplings, where it was converted into 2,3,4,6-tetra-O-benzyl-D-glucopyranose trichloroacetimidate using trichloroacetonitrile in the presence of a base such as potassium carbonate and DBU. Importantly, this imidate donor with no neighbouring participating groups is commonly used for the selective formation of α-glucosides. 2,3,4,6-tetra-O-benzyl-D-glucopyranose can also be oxidized to the lactone, or reduced to give the open chain form. Additionally, 2,3,4,6-tetra-O-benzyl-D-glucopyranose can be used for the preparation of glucono-1,5-lactone hydrazine, which was used, in-turn, to form a glucosylidene-spirocyclopropane.

Starting material for chiral-pool based organic synthesis

1,5-Anhydro-2,3,4-tri-O-benzoyl-D-threo-pent-1-enitol is a high purity compound that is synthesized from D-threo pent 1 enitol. It is a sugar that belongs to the category of complex carbohydrates. This product can be custom synthesized and modified according to customer requirements.

Isosorbide dinitrate is a drug that belongs to the class of nitrates. It is used in the treatment of angina pectoris, as well as congestive heart failure and chronic heart failure. Isosorbide dinitrate has been shown to cause caspase-independent cell death in human leukemia cells and breast cancer cells. This may be due to its ability to inhibit mitochondrial membrane potential and interfere with intracellular calcium mobilization. The optimum concentration for isosorbide dinitrate is 10 µM, which inhibits the growth of bacteria, including Mycobacterium tuberculosis and Salmonella enterica serovar Typhimurium. The drug also inhibits the production of proinflammatory cytokines such as IL-1β, IL-6, and TNF-α by inhibiting c-jun phosphorylation. Isosorbide dinitrate also has anti-inflammatory properties, which may be due to its ability to inhibit 4-hyd

3-O-benzyl-diacetonide-d-glucose is a synthetic monosaccharide that can be used as a building block for oligosaccharides and polysaccharides. It is custom synthesized to meet your specific needs and can be modified with fluorination, methylation, or glycosylation. 3-O-benzyl-diacetonide-d-glucose has been shown to have high purity and is available in small quantities for custom synthesis.

Ethyl 2,3,4-tri-O-benzyl-L-thiofucopyranoside is a glycosylation agent that is used in the synthesis of complex carbohydrates. It can also be used in the methylation and click modification of saccharides. Ethyl 2,3,4-tri-O-benzyl-L-thiofucopyranoside has been shown to have a high purity and can be custom synthesized to fit the needs of the customer. This product has a CAS number of 169532-17-6 and it is available in both monosaccharides and oligosaccharides.

Phenyl-beta-D-thioglucuronic acid is a drug that is used to treat inflammatory diseases and autoimmune diseases. It is a basic structure that has been shown to have anti-estrogenic effects in vitro, although the mechanism of action is not well understood. Phenyl-beta-D-thioglucuronic acid can be crosslinked with proteins to form a matrix for wound healing. This drug has also been shown to be a potent inhibitor of proteases, and may inhibit other enzymes such as matrix metalloproteinases and serine proteases.

2,3,4,6-Tetra-O-benzyl-D-glucopyranose is a selectively protected intermediate, where the anomeric 1-O-hydroxyl group is free. This hemiacetal has been used successfully as an intermediate for glucosylation couplings, where it was converted into 2,3,4,6-tetra-O-benzyl-D-glucopyranose trichloroacetimidate using trichloroacetonitrile in the presence of a base such as potassium carbonate and DBU. Importantly, this imidate donor with no neighbouring participating groups is commonly used for the selective formation of α-glucosides. 2,3,4,6-tetra-O-benzyl-D-glucopyranose can also be oxidized to the lactone, or reduced to give the open chain form. Additionally, 2,3,4,6-tetra-O-benzyl-D-glucopyranose can be used for the preparation of glucono-1,5-lactone hydrazine, which was used, in-turn, to form a glucosylidene-spirocyclopropane.