Monosacáridos

Fluconazole D-glucuronide is a synthetic, fluorinated sugar that has been modified with a glycosylation. It is synthesized by reacting fluconazole with the sugar glucuronic acid in the presence of an enzyme called glycosyltransferase. Fluconazole D-glucuronide is a custom synthesis, and it can be used as a pharmaceutical intermediate to produce other compounds. Fluconazole D-glucuronide is also used as an analytical standard for quantifying fluconazole in biological samples.

D-tagatose 1-phosphate is a cytosolic intermediate of tagatose, which is found in many dietary sources. It has been shown to have regulatory effects on mitochondrial membrane potential and peroxisome proliferation in human cells. D-tagatose 1-phosphate also has been shown to have clinical relevance for humans with liver disease, as it enhances aerobic glycolysis and increases adenine nucleotide levels.

Iminosugar 1 is a fluorinated saccharide that belongs to the group of carbohydrates. It is synthesized by the modification of glucose with a fluorine atom. This modification prevents crystallization and increases solubility in water. Iminosugar 1 has been modified by methylation and glycosylation to increase its stability. This product is available as a custom synthesis, and has high purity.

Ramipril acyl-b-D-glucuronide is a glycosylated prodrug that is the active form of ramipril, an ACE inhibitor. It is metabolized in the liver to ramipril and excreted in the urine. Ramipril acyl-b-D-glucuronide has been shown to have an increased bioavailability and a longer half-life than ramipril due to its glycosylation. The synthesis of this drug has been modified by methylation, fluorination, and saccharide modification. This compound is also available as a custom synthesis for research purposes with high purity.

Olmesartan acid O-b-D-glucuronide is a synthetic, high purity, and custom synthesis oligosaccharide. It can be fluorinated in the presence of a base to give a fluorinated compound with the following CAS number: 369395-57-3. Olmesartan acid O-b-D-glucuronide is an oligosaccharide that has been modified by click chemistry. This modification results in a polysaccharide that contains saccharides connected through ether linkages. The saccharides are made up of monosaccharides and disaccharides, which are all sugars.

1,5-Dideoxy-1,5-imino-D-xylitol is a synthetic molecule that inhibits the enzyme glycinamide ribonucleotide transformylase (GART) and blocks the synthesis of purines. 1,5-Dideoxy-1,5-imino-D-xylitol has been shown to be potent in inhibiting GART with an IC50 of 0.3 μM. This inhibitory effect was observed in Sprague Dawley rats after oral administration of 1,5-dideoxy-1,5 imino D xylitol at a dose of 10 mg/kg. The inhibition was found to be specific for amination reactions that are catalyzed by GART and not by other enzymes such as glycine amidinotransferase or adenylate kinase. It can be used to study the structure and function of tissue cells.

2,5-Anhydro-D-mannofuranose oxime is a glycosylation inhibitor that prevents the formation of glycosidic bonds. It is used in the synthesis of complex carbohydrates, such as polysaccharides and oligosaccharides. This compound can be fluorinated or methylated to produce 2,5-anhydro-D-mannofuranose oxime derivatives that are useful for click chemistry. 2,5-Anhydro-D-mannofuranose oxime has been shown to inhibit the enzymatic conversion of mannitol to mannose and fructose by blocking the enzyme alpha mannosidase. The high purity of this compound makes it suitable for use in a variety of reactions, including glycobiology studies and carbohydrate modifications.

2-epi-(-)-emtricitabine is an analog of the nucleoside cytidine, which inhibits the phosphorylation and subsequent degradation of deoxycytidine kinase, thereby blocking the production of the viral DNA polymerase. The compound also inhibits tyrosine kinases, which are enzymes that play a vital role in cell signaling. This inhibition may contribute to its antiviral activity. 2-epi-(-)-emtricitabine has been shown to inhibit human immunodeficiency virus (HIV) replication in vitro and in vivo. It is a prodrug that is converted to emtricitabine, its active form, by deoxycytidine kinase and then hydrolyzed by esterases. 2-epi-(-)-emtricitabine has been shown to be effective against hepatitis B virus and cancer cells.