Péptidos
Subcategorías de "Péptidos"
Se han encontrado 29610 productos de "Péptidos"
Hepcidin-20 (Human)
CAS:Hepcidin-20 consists of the disulfide Bonds: Cys2-Cys18, Cys5-Cys8, Cys6-Cys14, and Cys9-Cys17 and is available in the trifluoroacetate salt form. Hepcidin-20 is a truncated form of the peptide hormone hepcidin-25, which plays a key role in the regulation of iron metabolism in the body. It is produced by the liver and is secreted into the bloodstream. Hepcidin has the ability to regulate the activity of ferroportin, a protein that facilitates the export of iron from cells into the bloodstream. It binds to ferroportin and inhibits its activity, leading to decreased iron absorption from the diet and reduced iron release from cells. The biological significance of hepcidin-20 is still being studied, but it may be involved in the regulation of iron metabolism in certain situations, such as inflammation or certain disease states. Like hepcidin-25, hepcidin-20 is a target for the development of treatments for iron-related disorders, such as anemia of chronic disease and hemochromatosis.Fórmula:C85H135N27O23S9Pureza:Min. 95%Peso molecular:2,191.77 g/molH-EGYLQIGANTQAAQK^-OH
Peptide H-EGYLQIGANTQAAQK^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.H-Ser-Leu-Ile-Gly-Lys-Val-NH2
CAS:H-Ser-Leu-Ile-Gly-Lys-Val-NH2 is a synthetic peptide that is a cyclase inhibitor. It binds to the receptor for neurokinin 1, which has been shown to inhibit lacrimal gland function in rats. The compound also inhibits the synthesis of epidermal growth factor and has been shown to have anti-inflammatory effects in mouse models. H-Ser-Leu-Ile-Gly-Lys-Val-NH2 has also been shown to inhibit protease activity in rat prostate cells and can be used as a chemical inhibitor for proteases.Fórmula:C25H54N8O7Pureza:Min. 95%Peso molecular:614.79 g/molFmoc-D-Cys(Trt)-OH
CAS:Fmoc-D-Cys(Trt)-OH is a synthetic peptide that can be used as a research tool in cell biology and pharmacology. It has an ion channel blocking effect and is a potent activator of the receptor GPR75. Fmoc-D-Cys(Trt)-OH is soluble in water and displays high purity, with a CAS No. 167015-11-4. This product can be used to study protein interactions, ion channels, and receptors. Fmoc-D-Cys(Trt)-OH can also be used as an antibody or cell biology reagent, as well as an inhibitor for certain enzymes such as tyrosine hydroxylase.Fórmula:C37H31NO4SPureza:Min. 95%Peso molecular:585.73 g/molCOMU Reagent
CAS:COMU reagent is a copper-containing, natural compound that can be used in intrauterine diagnosis. The COMU reagent has been shown to have potent antagonistic activity against the CB2 receptor and hydrogen bond donor site. This product also can be used to detect the presence of peptide hormones, such as LH and FSH, in urine samples. The COMU reagent has been shown to bind to integrin receptors on cells, which are involved in cell adhesion and migration. The conformational properties of this compound allow it to form a complex with cyclic peptides that are found in human liver cells infected with hepatitis C virus (HCV).Fórmula:C12H19N4O4F6PPureza:Min. 95%Peso molecular:428.27 g/molPyClocK®
CAS:PyClocK® is a monoclonal antibody that binds to the HIV-1 surface protein, gp120. It is used in diagnostic immunoassays for the detection of anti-HIV antibodies and in preparative high performance liquid chromatography (HPLC) of glycopeptides, which are cyclic peptides that are produced by bacteria. PyClocK® also has been shown to bind to vasoactive intestinal peptide and cyclic peptide receptors, which may be involved in autoimmune diseases or metabolic disorders. The conformational properties of this antibody have been determined using X-ray crystallography on the monoclonal antibody.Fórmula:C18H27N6OF6ClP2Pureza:Min. 98.0 Area-%Peso molecular:554.85 g/molH-R^F^-OH
Peptide H-R^F^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.
LCBiot-IPESSELTLQELLGEERR-NH2
Peptide LCBiot-IPESSELTLQELLGEERR-NH2 is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.
H-IP^TTFENGR^-OH
Peptide H-IP^TTFENGR^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly
Custom research peptide; min purity 95%. For different specs please use the Peptide Quote Tool
Fórmula:C45H82N12O12S1Peso molecular:1,015.27 g/molAc-CEKEEDERVQGGDREPLLQEE-OH
Peptide Ac-CEKEEDERVQGGDREPLLQEE-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.Phosphorylated Protein Kinase C Substrate 2
Custom research peptide; min purity 95%. For different specs please use the Peptide Quote ToolFórmula:C34H69N16O11PPeso molecular:909.02 g/molDystrophin (2765-2777)
Forms of inherited muscular dystrophy such as Duchenne muscular dystrophy (DMD) and Becker muscular dystrophy (BMD) result from mutations targeting the dystrophin gene. These disorders are X-linked, progressive, and cause the gradual weakening of the muscles leading to respiratory failure and ultimately reduces the patient lifespan.In DMD, mutations lead to the production of premature stop codons and hence the truncated dystrophin protein product is vulnerable to nonsense mediated decay and degradation. Therefore, dystrophin production in muscle cells is reduced. On the other hand, nonsense mutations which also contribute to DMD, cause exon skipping in BMD and result in an internally truncated protein product which are partially functional. The symptoms of BMD are later onset compared with DMD which develop in patients between 2 to 7 years.Treatments of dystrophin disorders are in clinical trial including antisense oligonucleotide exon skipping and gene therapy. However, the efficacies of these treatments are not easily quantified. Currently levels of muscular dystrophin are quantified by western blot which can be unreliable. The peptide provided here, aligning residues dystrophin (2690-2700), has been tested via mass spectrometry to provide a more reliable method of validation of dystrophin levels. Further study with this dystrophin fragment could prove to be a vital step in the understanding and treatment of dystrophin disorders. Within our catalogue we also have other peptides tested for dystrophin quantification available plus the full-length dystrophin protein.Peso molecular:1,401.7 g/molGHK tripeptide
CAS:The GHK tripeptide has many attributes which can positively impact human health. GHK can improve tissue repair, exhibit anti-cancer and anti-inflammatory properties, suppress age related molecules and restore chronic obstructive pulmonary disease fibroblasts.The GHK tripeptide is found in the human plasma and binds copper. It exerts its effects through its ability to up regulate and downregulate 4,000 human genes. Due to its ability to protect and regenerate aspects of human health, GHK-Cu can be used in products for skin and hair.Specifically during skin regeneration GHK-Cu can promote the synthesis of collagen and glycosaminoglycans, increase the rate of wound healing and the formation of blood vessels.
Fórmula:C14H24N6O4Forma y color:PowderPeso molecular:340.2 g/molGuanylin
CAS:Guanylin peptide hormone which is an activator of the transmembrane receptor Guanylate Cyclase C located on the surface of intestinal epithelial cells. It is sourced from Rat, Mouse species and contains disulfide bonds between Cys4-Cys12 and Cys7-Cys15.
Fórmula:C60H90N16O22S4Pureza:Min. 95%Peso molecular:1,515.7 g/molH-GDLIAEVETDK^ATV-OH
Peptide H-GDLIAEVETDK^ATV-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.H-GQVLVFLGQSEGLR^-OH
Peptide H-GQVLVFLGQSEGLR^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.H-GDVFVIR^-OH
Peptide H-GDVFVIR^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.H-TITLEVESSDTIDNVK^-OH
Peptide H-TITLEVESSDTIDNVK^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.H-FL^GYLILGV-OH
Peptide H-FL^GYLILGV-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.
H-YVRPGGGFVPNFQLFEK^-OH
Peptide H-YVRPGGGFVPNFQLFEK^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.
H-VLELTSDNDR^-OH
Peptide H-VLELTSDNDR^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.Fmoc-D-Asp(OtBu)-OH
CAS:Fmoc-D-Asp(OtBu)-OH is a cell biology research tool that can be used to study protein interactions and ion channels. It also has been used as an inhibitor for the activation of receptor tyrosine kinases, including human epidermal growth factor receptor 2 (HER2) in breast cancer cells. Fmoc-D-Asp(OtBu)-OH is a high purity compound that is available with CAS No. 112883-39-3.
Fórmula:C23H25NO6Pureza:Min. 95%Peso molecular:411.46 g/molH-FLRGRAYGL^-OH
Peptide H-FLRGRAYGL^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.H-DIVGAVLK^-OH
Peptide H-DIVGAVLK^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.Bid BH3-r8 TFA
Catalogue peptide; min. 95% purityFórmula:C145H260N66O41S•(C2HF3O2)xPeso molecular:3,616.17 g/molH-MDYKDHDGDYKDHDIDYKDDDDK-NH2
Peptide H-MDYKDHDGDYKDHDIDYKDDDDK-NH2 is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.
Amyloid Beta-Protein (40-1)
CAS:Amyloid Beta-Protein (40-1) is a peptide that is found in the brain, and is thought to be involved in Alzheimer’s disease. Amyloid Beta-Protein (40-1) has been shown to inhibit protein interactions and activator functions, as well as act as a ligand for receptors. This protein can be used as a research tool for studying ion channels and antibodies. It also has high purity and can be used for life science experiments.Fórmula:C194H295N53O58SPureza:Min. 95%Peso molecular:4,329.8 g/molH-Ala-Tyr-Pro-Gly-Lys-Phe-OH
CAS:H-Ala-Tyr-Pro-Gly-Lys-Phe-OH is a peptide that activates toll-like receptor 4 (TLR4). It is a potent inhibitor of the enzyme phospholipase A2 and has been shown to inhibit the production of proinflammatory cytokines, such as IL1β, IL6, IL8, and TNFα. This peptide also has anti-inflammatory effects on autoimmune diseases, such as rheumatoid arthritis. H-Ala-Tyr-Pro-Gly-Lys-Phe-OH has been shown to inhibit prostate cancer cell growth in vitro and in vivo. It appears to exert its action by interfering with the transcriptional process at the level of RNA polymerase II. The mechanism may involve inhibition of the activation of basic fibroblast cells or suppression of epidermal growth factor signaling. H-Ala-Tyr - Pro - Gly - Lys - Phe -
Fórmula:C34H47N7O8Pureza:Min. 95%Peso molecular:681.78 g/molFmoc-Lys(Palmitoyl-Glu-OtBu)-OH
CAS:This is a building block for peptide synthesis. It is a protected lysine derivative that can be used in the formation of peptides. This functionalized lysine derivative can be deprotected and reacted with other amino acids to form peptides. The protecting group, Fmoc, protects the lysine from unwanted reactions during the synthesis process. The side chain, Palmitoyl-Glu-OtBu, allows for the attachment of other molecules to the lysine side chain.Fórmula:C46H69N3O8Pureza:Min. 95%Peso molecular:792.08 g/molN-L-Glutamyl-L-Lysine
The human oligopeptide transporter (PEPT1) is a critical transporter of dipeptides, tripeptides, and peptide-like drugs, including β-lactam and cephalosporin antibiotics, and ACE inhibitors. Therefore, there is an effort to understand better the transport mechanism and substrate requirements of PEPT1 to improve drug uptake.N-L-Glutamyl-L-Lysine is a dipeptide that naturally occurs in the body during protein degradation. It has been used in functional transport assays with other dipeptides to understand PEPT1 binding specificity with substrates and how this affects the conformation. N-L-Glutamyl-L-Lysine, along with other short peptides, is a vital tool in studying facilitator transporters like PEPT1. N-L-Glutamyl-L-Lysine has two charges and forms an intramolecular salt bridge that places the side chains in close proximity to fit the transporter better. N-L-Glutamyl-L-Lysine has helped understand that PEPT1 doesn't bind all dipeptides, and not all bound peptides are transported. Further work with N-L-Glutamyl-L-Lysine could further define the structure&minus-transport relationships of PEPT1 for better drug transportation.Peso molecular:275.1 g/molH-NGFFF-NH2
Peptide H-NGFFF-NH2 is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.Mage-1 Antigen (161-169), human
CAS:Custom research peptide; min purity 95%. For different specs please use the Peptide Quote Tool
Fórmula:C41H57N11O17Peso molecular:975.97 g/molH-Phe-Ser-Leu-Leu-Arg-Tyr-NH2
CAS:This is a synthetic peptide that was originally isolated from human colon tissue. It has been shown to sensitize dorsal root ganglia neurons in vitro, producing a response to the neurotransmitter acetylcholine. This peptide also induces apoptosis in neuronal cells and increases the permeability of blood vessels in tissues by activating vasoactive intestinal peptide (VIP) receptors. The effects of this peptide were studied in humans with bowel disease or inflammatory bowel disease. It was found that it may be effective for treating these diseases as well as necrosis factor-mediated inflammation. This peptide is also known to activate IL-10, which is an anti-inflammatory cytokine.Fórmula:C39H60N10O8Pureza:Min. 95%Peso molecular:796.98 g/molH-Ser-Phe-Leu-Leu-Arg-Asn-Pro-Asn-Asp-Lys-Tyr-Glu-Pro-Phe-NH2
CAS:H-Ser-Phe-Leu-Leu-Arg-Asn-Pro-Asn-Asp-Lys-Tyr-Glu-Pro-Phe is a peptide that is activated by incubation with collagen. It has been shown to have an inhibitory effect on thrombin receptor and the activation of coagulation factors, which may be due to its ability to desensitize the receptor. HSLRAPAP can also be used in cancer therapy. In animal studies, it has been shown to inhibit tumor growth and metastasis. HSLRAPAP has also been shown to stimulate the production of platelets in animals, which may account for its antiplatelet properties.Fórmula:C83H120F3N21O24Pureza:Min. 95%H-SFGWDLAK^-OH
Peptide H-SFGWDLAK^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.H-Ser-Phe-Leu-Leu-Arg-OH
CAS:H-Ser-Phe-Leu-Leu-Arg-OH is a cyclic peptide that has been shown to have cytotoxic effects against cells of the atherosclerotic lesion in vivo. It also has antioxidant properties and can be used as a biocompatible polymer for the treatment of autoimmune disease. This drug is not potent enough to be used as an antibacterial agent but is effective against some strains of Mycobacterium tuberculosis and Mycobacterium avium complex. This drug binds to integrin receptors on cells, which may account for its low potency.Fórmula:C30H50N8O7Pureza:Min. 95%Peso molecular:634.77 g/molBNP-32 human
CAS:This 32 amino acid peptide contains a 17 amino acid ring structure that is common to all natriuretic peptides. It is also called the brain natriuretic peptide (BNP) because it was first identified in porcine brain- however, the main source of this peptide is not the brain but the cardiac ventricle. This cardiac neurohormone is secreted from the ventricles in response to volume expansion and pressure overload. It has natriuretic and vasodilatory effects and suppresses the renin-angiotensin-aldosterone system.
Fórmula:C143H244N50O42S4Forma y color:PowderPeso molecular:3,463.8 g/molAc-SGVGNDLVL-NH2
Peptide Ac-SGVGNDLVL-NH2 is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.CMVpp65 - 49 (VALRHVVCAHELVCS)
Custom research peptide; min purity 95%. For different specs please use the Peptide Quote ToolPeso molecular:1,636 g/molLCBiot-LSALTPSPSWLKYKAL-NH2
Peptide LCBiot-LSALTPSPSWLKYKAL-NH2 is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.PTH (1-13) Human
N-terminal tryptic peptide of parathyroid hormone (PTH), used for quantification and optimisation in LC-MS/MS assays.PTH is an 84-amino-acid polypeptide hormone (PTH 1-84) which is secreted by the parathyroid glands along with its fragments (such as PTH 1-34 and PTH 7-84). PTH increases calcium and decrease phosphate levels in the blood and the abundance of PTH-derived peptides is regulated by blood calcium levels. PTH inhibits the bone growth-promoting activity of osteoblasts and induces osteoclasts to resorb bone and release calcium and phosphate ions into the blood. PTH binds to and activates the receptor parathyroid hormone receptor 1 (PTHR1). PTHR1 is a G-protein-coupled receptor (GPCR) which regulates mineral ion homeostasis, bone turnover and skeletal development
Peso molecular:1,454.8 g/molH-LL^EAAR-OH
Peptide H-LL^EAAR-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.H-ILGGHLDAK^-OH
Peptide H-ILGGHLDAK^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.
Ac-PLLA-OH
Peptide Ac-PLLA-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.
MOG (92-106) Mouse, Rat
Myelin oligodendrocyte glycoprotein (MOG) is a member of the immunoglobulin (Ig) protein superfamily and is expressed exclusively in the central nervous system (CNS) on the surface of myelin sheaths and oligodendrocyte processes. MOG is expressed at the onset of myelination, and therefore is a potential marker for oligodendrocyte maturation.MOG contains an extracellular domain, a transmembrane domain, a cytoplasmic loop, a membrane-associated region and a cytoplasmic tail.- MOG may function as a cell surface receptor or cell adhesion molecule. -Fifteen different alternatively spliced isoforms have been detected in humans. These are present either on the cell surface, the endoplasmic reticulum in the endocytic system, or in secreted form.The secreted form of MOG may trigger autoimmunity if released into the cerebrospinal fluid and periphery. MOG is thought to be a key target for autoantibodies and cell-mediated immune responses in inflammatory demyelinating diseases such as multiple sclerosis (MS) and is therefore widely studied in this field.Fragment 92-106 of MOG is able to induce experimental autoimmune/allergic encephalomyelitis (EAE), an animal model that resembles MS.Forma y color:PowderPeso molecular:1,823.9 g/molAc-EEMQRR^-NH2
Peptide Ac-EEMQRR^-NH2 is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.
Val-Ile-Ile
Custom research peptide; min purity 95%. For different specs please use the Peptide Quote ToolFórmula:C17H33N3O4Peso molecular:343.46 g/mol[Sulfo-Cyanine3]-LifeAct (Abp140 1-17)
[Sulfo-Cyanine3]-LifeAct (Abp140 1-17) contains the fluorophore sulfo-cyanine3 and the 17 amino acid peptide lifeact derived from amino acids 1-17 of the Saccharomyces cerevisiae actin binding protein, Abp140. These first 17 amino acids of Abp140 are crucial in allowing lifeact to localise to actin filaments (F-actin) and therefore it can be used as a cytoskeletal marker. One application of lifeact is in the study of plant development and pathogen defence as filamentous actin within the plant's actin cytoskeleton is important in key processes such as cell division, membrane trafficking and stomatal movements. The addition of Atto655 which has single molecule (SM) imaging properties allows the location of lifeAct (Abp140 1-17) binding to be detected.Peso molecular:2,521.2 g/molMartentoxin I
A synthetic scorpion toxin, sourced from the Scorpion, Buthus martensi which has the following disulfide bonds: Cys8-Cys29, Cys14-Cys34, and Cys18-Cys36. This product is available in the trifluoroacetate salt form. One-Letter-Code: FGLIDVKCFA SSECWTACKK VTGSGQGKCQ NNQCRCYFórmula:C162H253N49O52S6Pureza:Min. 95%Peso molecular:3,911.5 g/molH-GLPSSI^EK^-OH
Peptide H-GLPSSI^EK^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.Toll-Interleukin 1 Receptor (TIR) Domain Containing Adaptor Protein (TIRAP) (Isoform b)
Custom research peptide; min purity 95%. For different specs please use the Peptide Quote ToolBQ-123 Sodium Salt
CAS:BQ-123 is a cyclic peptide that blocks the endothelin-A receptor. It has been shown to be an effective treatment for pain and inflammation associated with osteoarthritis, rheumatoid arthritis, and other inflammatory conditions. BQ-123 binds to the endothelin-A receptor, which is located on the surface of cells in many tissues throughout the body. When bound, it inhibits intracellular calcium concentrations by reducing voltage-gated calcium channels and prevents the release of neurotransmitters. BQ-123 also has a stabilizing effect on hydrogen bonds due to its charged side chains. This property may account for its ability to form stable complexes with other proteins, inhibiting their function. BQ-123 has been shown to have an active binding site on cyclic AMP response element binding protein (CREB) that inhibits CREB activity, thereby reducing protein synthesis. It also blocks cyclic GMP (cGMP)-dependent protein kinFórmula:C31H42N6O7Pureza:Min. 95%Peso molecular:610.70 g/molH-RAAAAAAR-NH2
Peptide H-RAAAAAAR-NH2 is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.
H-DRVYIHPF-NH2
Peptide H-DRVYIHPF-NH2 is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.
H-EIAQDFK^-OH
Peptide H-EIAQDFK^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.LCBiot-KEELDKYFKNHTSPDVDLG-OH
Peptide LCBiot-KEELDKYFKNHTSPDVDLG-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.Pyroglutamyl beta-Amyloid (4-14) Biotin
Pyroglutamyl β-Amyloid (4-14) Biotin is derived from Amyloid-β, which has been identified as the key subunit of the extracellular plaques found in the brains of patients with Alzheimer's disease (AD) and Down's syndrome (DS). Aβ has therefore been extensively studied as a potential target for treatment of AD.Aβ is formed from the cleavage of the large, transmembrane protein- APP (amyloid precursor protein). Cleavage of APP by β- and then γ-secretases results in the formation of Aβ. Aβ can aggregate to produce amyloid-β oligomers, which are thought to be highly neurotoxic. Over time Aβ can further aggregate to produce the characteristic senile plaques present in AD and DS. Aβ can be degraded by enzymes such as neprilysin, insulin degrading enzyme or endothelin converting enzyme. At physiological levels Aβ may be involved in controlling synaptic activity and neuronal survival.This peptide contains a C-terminal Biotin tag that is covalently bonded via ethylenediamine and can be used for detection and purification. Additionally, there is a Pyroglutamyl molecule located at the N-terminal position.Peso molecular:1,761.8 g/molHIV - 1 MN ENV - 25
Custom research peptide; min purity 95%. For different specs please use the Peptide Quote Tool
Peso molecular:1,859.1 g/molH-GMNYLEDR^-OH
Peptide H-GMNYLEDR^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.Ala-AMC
CAS:Ala-AMC is a fluorescent peptide that binds to the receptor AMPA and activates it. This product is used in research as a tool for studying protein interactions, cellular biology and pharmacology.Fórmula:C13H14N2O3Pureza:Min. 95%Peso molecular:246.26 g/molH-GEGGPQGPR^-OH
Peptide H-GEGGPQGPR^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.
Ac-PKKKRKVEDPYC-NH2
Peptide Ac-PKKKRKVEDPYC-NH2 is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.Ac-Tyr-Val-Gly
CAS:Ac-Tyr-Val-Gly is a mitochondrial protein that regulates mitochondrial functions and is involved in the regulation of apoptosis. Ac-Tyr-Val-Gly interacts with nuclear DNA and regulates transcription, translation, and replication. Ac-Tyr-Val-Gly has been shown to be toxic to liver cells; however, it has been shown to have no effect on neuronal death or apoptosis pathway. These effects may be due to its ability to induce proteolytic activity in neurons and its ability to activate proapoptotic proteins such as Bax.Fórmula:C18H25N3O6Pureza:Min. 95%Peso molecular:379.41 g/molH-EQLSSVSSF^ER-OH
Peptide H-EQLSSVSSF^ER-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.H-V^VGGLVALR^-OH
Peptide H-V^VGGLVALR^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.Neuropeptide S rat
Neuropeptide S (NPS) is a neuropeptide found in mammalian brains, primarily in neurons in the lateral parabrachial nucleus, the-peri-locus coeruleus and the principle sensory 5 nucleus of the trigeminus. NPS is involved in several neuroendocrine, behavioural and inflammatory responses, including: reducing anxiety in mice- suppressing appetite and inducing wakefulness and hyperactivity. NPS treatment can be used to improve fear extinction in mice and limit fear memory retrieval after fear reduction training, thus making it an interesting target for treatment of post-traumatic stress disorder. NPS exerts its actions by binding to a G-protein coupled receptor, NPSR
Forma y color:PowderPeso molecular:2,209.2 g/molAc-SHAVSS-NH2
Peptide Ac-SHAVSS-NH2 is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.Fmoc-Cys(Pam)2-OH
CAS:Fmoc-Cys(Pam)2-OH is a building block that can be used in the synthesis of lipopeptides. It is used in the research of vaccines and has been shown to target tumor cells.
Fórmula:C53H83NO8SPureza:Min. 95%Peso molecular:894.32 g/molCART (Human, 55-102)
CAS:CART is a peptide that acts as an activator for the CART receptor. It has been shown to be a ligand for the CART receptor and blocks calcium channels in cell culture. It is a potent inhibitor of ion channels, which are proteins that allow ions to pass through the membrane of cells. CART is also used as a research tool in cell biology, pharmacology, and life science.Fórmula:C225H365N65O65S7Pureza:Min. 95%Peso molecular:5,245.2 g/molH-LGGDLGTYVINK^^-OH
Peptide H-LGGDLGTYVINK^^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.HPV16 E7 (86-93)
Immunogenic Human Cytotoxic T lymphocytes (CTL) epitope encoded by human papillomavirus 16 type E7 with very high affinity binding to the HLA-A*0201 molecule.
Forma y color:PowderPeso molecular:814.5 g/molHLA leader peptide LIL
Peptide H-VMAPRTLIL-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.
HXB2 gag NO-79/aa313 - 327
Custom research peptide; min purity 95%. For different specs please use the Peptide Quote ToolPeso molecular:1,761 g/molIL-33 peptide
IL-33 is a member of the IL-1 superfamily of cytokines, a determination based in part on the molecules β-trefoil structure, a conserved structure type described in other IL-1 cytokines. IL-33 acts intracellularly as a nuclear factor and extracellularly as a cytokine.IL-33 has been associated with several disease states through Genome Wide Association Studies: asthma, allergy, endometriosis and hay fever. A single-nucleotide polymorphism rs928413 (A/G), is located in the 5' upstream region of IL33 gene, and its minor 'G' allele was identified as a susceptible variant for early childhood asthma and atopic asthma development.Peso molecular:1,031.6 g/molCys-TAT (49-57)
Cys- Modified HIV TAT Sequence 49-57, a derivatizable cell-penetrating peptide (CPP) for click chemistry. Product available as a Trifluoroacetate SaltFórmula:C56H112N32O11SPureza:Min. 95%Peso molecular:1,441.79 g/molAc-LKISQAPQVSISRSKSYRENGAPFC-NH2
Peptide Ac-LKISQAPQVSISRSKSYRENGAPFC-NH2 is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.
Sifuvirtude
Inhibitor of HIV-1-mediated cell-cell fusion in a dose-dependent manner, and exhibits high potency against infections by a wide range of primary and laboratory-adapted HIV-1 isolates from multiple genotypes. Highly effective against T20 resistant strains.Peso molecular:4,725.2 g/molH-ALDLLDK^-OH
Peptide H-ALDLLDK^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.H-FTITAGSK^-OH
Peptide H-FTITAGSK^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.
H-SALVLQYLR^-OH
Peptide H-SALVLQYLR^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.H-FNKPFVFLMIEQNTK^-OH
Peptide H-FNKPFVFLMIEQNTK^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.Ac-SWFR-NH2
Peptide Ac-SWFR-NH2 is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.HSP70/DnaK Substrate Peptide
Model substrate peptide for heat shock protein 70 (HSP70)/ Chaperone protein DnaK. Binds to the substrate binding domain of DnaK and is used in co-crystallisation assays. DnaK is the most well studied heat shock proteins and is central in protein folding and in shuttling misfolded peptides to other chaperones and proteases for resolution. In the presence of ADP, this substrate peptide interacts with DnaK with high affinity, however when ATP is bound to DnaK, substrate binding is far weaker.Peso molecular:785.5 g/molLactacystin
CAS:Lactacystin is a peptide that acts as an activator of ion channels. It binds to the receptor and activates the ligand-gated ion channel, which then opens the ion channel. This leads to increased influx of ions into the cell and an increase in intracellular calcium concentration. Lactacystin has been used as a research tool for studies on protein interactions, such as antibody-antigen interactions and receptor-ligand interactions. Lactacystin is also used for pharmacological purposes, such as for pain relief or for treatment of epilepsy.Fórmula:C15H24N2O7SPureza:Min. 95%Peso molecular:376.43 g/molH-DLADELALVDVIEDK^-OH
Peptide H-DLADELALVDVIEDK^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.Visperas2pY
An immunoreceptor tyrosine-based activation motif (ITAM) is a phosphorylation site consisting of a conserved sequence of four amino acids that is repeated twice in the cytoplasmic tails of cell-surface non-catalytic tyrosine-phosphorylated receptors. The major role of ITAMs is its involvement in the initiation of signalling pathway and the subsequent activation of immune cells. The motif has the following structure: YxxL/I. where xx are any two amino acids. Two of these signatures are typically separated by between 6 and 8 amino acids in the cytoplasmic tail of the molecule (YxxL/Ix(6-8)YxxL/I). ITAMs are found in the CD3 and θ¶-chains of the T cell receptor (TCR) complex. TCR is a multi-subunit receptor on the surface of T cells. TCR contains two ligand binding chains containing 20 phosphorylation sites, distributed on 10 ITAMs. The TCR θ¶-chain is a homodimer subunit that contains six ITAMs (12 sites). These sites are phosphorylated by the membrane-anchored Src family tyrosine kinase Lck and Fyn and are dephosphorylated by the transmembrane phosphatases CD148 and CD45. When both tyrosines in an ITAM are phosphorylated they generate docking sites for the tandem SH2 domains of the cytosolic tyrosine kinase ZAP-70. Bound ZAP-70 can phosphorylate tyrosines on other substrates that initiate the signal transduction that leads to T cell activation. The multiple ITAMs on the TCR function mainly to amplify subsequent signalling.T cells rely on the TCR to recognize antigens, in the form of peptides bound to major histocompatibility complexes (MHC), on the surfaces of antigen-presenting cells. Binding of TCR to antigen-MCH complexes leads to proliferation, differentiation, and the secretion of effector cytokines, contributing to the elimination of infections.Peso molecular:2,672.1 g/molAngiotensin I-converting enzyme inhibitor 10
CAS:Custom research peptide; min purity 95%. For different specs please use the Peptide Quote Tool
Fórmula:C13H25N3O4Peso molecular:287.36 g/molH-YQTFFNPRT^FGSGE-OH
Peptide H-YQTFFNPRT^FGSGE-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.Apelin-36 Human
CAS:Apelin-36 (human) is derived from the apelin peptide which acts as a ligand for the apelin receptor (APJ) G protein coupled receptor and is a substrate for angiotensin converting enzyme 2. Preprapelin, encoded for by APLN located on Xq25-26.1, is cleaved to form either apelin 36, apelin 17, apelin 13, or apelin 12. As a member of the adipokine hormone family, which are involved in processes such as vascular homeostasis and angiogenesis, apelin is secreted from adipose tissue.Both apelin and the apelin receptor are widely distributed around the body thus apelin has been found to be associated with cardiovascular diseases, obesity, diabetes and cancer. Studies exploring myocardial infarction showed there to be greater apelin mRNA expression during human heart failure compared to in healthy tissue. Apelin protects against heart failure due to, the pyroglutamyl form of apelin, playing a role in decreasing infarct size of myocardial infarctions. Furthermore in rats with hypertension, the expression of apelin and APJ was decreased.Peso molecular:4,193.3 g/molH-MPRHSRAKRAPRPSAC-NH2
Peptide H-MPRHSRAKRAPRPSAC-NH2 is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.H-LRRQHAR^ASHLGLAR-OH
Peptide H-LRRQHAR^ASHLGLAR-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.
Cyclo(CLLFVY)
Cyclo(CLLFVY) is a cyclic peptide which binds to the PAS-B domain of HIF-1alpha, thus inhibiting HIF-1 dimerisation and HIF-1 mediated hypoxia signalling.Peso molecular:738.4 g/molH2N-Gly-Pro-Leu-Gly-Val-Arg-Gly-Cys-COOH
Custom research peptide; min purity 95%. For different specs please use the Peptide Quote ToolFórmula:C31H55N11O9S1Peso molecular:757.9 g/molH-CLAVEEVSL^-OH
Peptide H-CLAVEEVSL^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.TNF-alpha (1-26), human
Peptide derived from tumour necrosis factor alpha (TNF-α), a cytokine produced by macrophages, T lymphocytes and natural killer cells. It exerts its function through targeting the transmembrane receptors TNF receptor 1 and TNF receptor 2, the latter of which it has a higher affinity for. When binding to TNF receptor 1 TNF-alpha is pro-apoptotic and when binding to TNF receptor 2 it is anti-apoptotic. TNF-α has further roles in inflammation, immunity and cancer.Expression of the TNF-α gene, located on chromosome 6 in humans is regulated by factors such as nuclear factor kappa b (NFKB).Dysregulation of TNF-α and its receptors can contribute to diseases such as rheumatoid arthritis, Crohn disease and diabetes. Anti-TNF-α can be used as a therapeutic agent to target TNF-α during inflammatory diseases.Peso molecular:2,729.4 g/mol
![[Sulfo-Cyanine3]-LifeAct (Abp140 1-17)](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F3D%2Fthumb-webp%2FCRB1130630.webp&w=3840&q=75)
