3'-Azido-2',3'-dideoxyuridine
CAS: 84472-85-5
Ref. 3D-NA05737
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Información del producto
- 3’-beta-Azido-2’,3’-dideoxyuridine3'-Azido-2',3'-dideoxy-D-uridine
- 1-(2,3-dideoxy-3-triaza-1,2-dien-2-ium-1-ylpentofuranosyl)pyrimidine-2,4(1H,3H)-dione
3'-Azido-2',3'-dideoxyuridine is an analog of the nucleoside dideoxyuridine that inhibits HIV replication. It has a high inhibitory dose and low toxicity. 3'-Azido-2',3'-dideoxyuridine is converted to its active form, 3'-azido-2',3'-dideoxythymidine (AZT), by dephosphorylation in human serum. AZT inhibits HIV replication by competing with the natural substrate for viral DNA polymerase, thereby inhibiting synthesis of viral DNA. 3'-Azido-2',3'-dideoxyuridine has been shown to be effective against hepatitis B virus and hepatitis C virus in cell cultures.
Propiedades químicas
Consulta técnica sobre: 3D-NA05737 3'-Azido-2',3'-dideoxyuridine
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