Oltipraz

CAS: 64224-21-1

Ref. TM-T0153

Información del producto

• Nombre: Oltipraz
• Sinónimos: NSC 347901, RP 35972, 3H-1,2-Dithiole-3-thione, 4-methyl-5-(2-pyrazinyl)-, 3H-1,2-Dithiole-3-thione, 4-methyl-5-pyrazinyl-, 4-Methyl-5-(2-pyrazinyl)-3H-1,2-dithiole-3-thione, 4-Methyl-5-pyrazinyl-3H-1,2-dithiole-3-thione, 4-methyl-5-(pyrazin-2-yl)-3H-1,2-dithiole-3-thione, 5-(2-Pyrazinyl)-4-methyl-1,2-dithiole-3-thione, Brn 0978110, Ccris 4048, Nsc 347901, Oltipraz [INN], Oltiprazum, Oltiprazum [INN-Latin], Rp 35972, Unii-6N510Jul1Y
• CAS: 64224-21-1

Descripción

Oltipraz (RP 35972) is a synthetic dithiolethione with potential chemopreventive and anti-angiogenic properties. Oltipraz induces phase II detoxification enzymes, such as glutathione S transferase (GST) and NAD(P)H: quinone oxidoreductase 1 (NQO1). The induction of detoxification enzymes enhances the detoxification of certain cancer-causing agents, thereby enhancing their elimination and preventing carcinogen-induced DNA damages. Although the exact mechanism through which the anti-angiogenesis effect remains to be fully elucidated, oltipraz maybe able to modulate the expression of a number of angiogenic factors, thereby blocking the sustained and focal neovascularization in multiple tumor cell types.

• Marca: Targetmol

Propiedades químicas

• Peso molecular: 226.34
• Fórmula: C₈H₆N₂S₃
• Pureza: 99.56%
• Color/Forma: Solid