CBR-5884
CAS: 681159-27-3
Ref. TM-T14884
2mg | 46,00 € | ||
5mg | 68,00 € | ||
10mg | 94,00 € | ||
25mg | 212,00 € | ||
50mg | 367,00 € | ||
100mg | 550,00 € | ||
1ml*10 (DMSO) | 74,00 € |
Información del producto
- CBR5884
CBR-5884 is an selective, active of phosphoglycerate dehydrogenase (PHGDH) inhibitor with an IC50 of 33 μM. CBR-5884 inhibits de novo serine synthesis in cancer cells and is selectively toxic to cancer cell lines with high serine biosynthetic activity. CBR-5884 selectively inhibits the proliferation of melanoma and breast cancer lines that have a high propensity for serine synthesis. Biochemical characterization of the inhibitor revealed that it was a noncompetitive inhibitor that showed a time-dependent onset of inhibition and disrupted the oligomerization state of PHGDH
Propiedades químicas
Consulta técnica sobre: TM-T14884 CBR-5884
Si desea solicitar un presupuesto o realizar un pedido, por favor añada los productos deseados a su carrito y solicite un presupuesto o pedido desde el carrito. Es más rápido, más barato, y podrá beneficiarse de los descuentos y las ventajas disponibles.