Deshidrogenasa
Las deshidrogenasas son enzimas involucradas en las reacciones de oxidación-reducción de las vías metabólicas, desempeñando un papel central en la producción de energía y la respiración celular. Estas enzimas son cruciales para procesos como el ciclo del ácido cítrico, la glucólisis y la oxidación de ácidos grasos. Los inhibidores de deshidrogenasas son herramientas importantes en el estudio de enfermedades metabólicas, cáncer y estrés oxidativo. En CymitQuimica, ofrecemos una selección completa de inhibidores de deshidrogenasas para apoyar su investigación en metabolismo, biología del cáncer y bioquímica.
Se han encontrado 317 productos para "Deshidrogenasa".
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XEN723
CAS:XEN723 is a potent thiazolylimidazolidinone Stearoyl-CoA Desaturase (SCD1) inhibitor(IC50s of 45 and 524 nM in mouse and HepG2 cell, respectively).Fórmula:C21H20FN5O2SPureza:99.5%Forma y color:SolidPeso molecular:425.48Ref: TM-T13356
1mg52,00€5mg110,00€1mL*10mM (DMSO)132,00€10mg170,00€25mg289,00€50mg414,00€100mg583,00€200mg785,00€TC HSD 21
CAS:TC HSD 21 is a potent and highly selective inhibitor of 17β-hydroxysteroid dehydrogenase type 3 (IC50 = 14 nM).Fórmula:C17H12BrNO3S2Pureza:99.32%Forma y color:SolidPeso molecular:422.32ML390
CAS:ML390 exerts its potent differentiation effect on multiple leukemia models.Fórmula:C21H21F3N2O3Pureza:99.76%Forma y color:SolidPeso molecular:406.4KPLH1130
CAS:KPLH1130, a PDK inhibitor, boosts glucose tolerance and reduces inflammation in high-fat diet mice.Fórmula:C15H13N3O3Pureza:99.07%Forma y color:SolidPeso molecular:283.28Ref: TM-T11765
1mg79,00€1mL*10mM (DMSO)178,00€5mg205,00€10mg333,00€25mg560,00€50mg797,00€100mg1.071,00€500mg2.187,00€MF-438
CAS:MF-438 is an effective and orally bioavailable stearoyl-CoA desaturase 1 (SCD1) inhibitor (EC50: 2.3 nM for rSCD1).Fórmula:C19H18F3N5OSPureza:98.98% - 99.50%Forma y color:SolidPeso molecular:421.44Ref: TM-T16068
1mg92,00€2mg137,00€5mg203,00€1mL*10mM (DMSO)224,00€10mg310,00€25mg527,00€50mg755,00€100mg1.044,00€500mg2.088,00€Mutant IDH1 inhibitor
CAS:Mutant IDH1 inhibitor is an effective inhibitor of mutant IDH1 R132H (IC50: < 72 nM).Fórmula:C25H34N6O3Pureza:98.3%Forma y color:SolidPeso molecular:466.58Ref: TM-T16161
1mg39,00€5mg86,00€1mL*10mM (DMSO)89,00€10mg128,00€25mg210,00€50mg306,00€100mg429,00€200mg597,00€LY 345899
CAS:LY 345899 is a Folate analog and is a methylenetetrahydrofolate dehydrogenase and MTHFD2 inhibitor (IC50: 96 nM and 663 nM, respectively and a Ki: 18 nM forFórmula:C20H21N7O7Pureza:99.7%Forma y color:SolidPeso molecular:471.42Ref: TM-T15827
1mg46,00€5mg152,00€1mL*10mM (DMSO)157,00€10mg224,00€25mg371,00€50mg522,00€100mg713,00€200mg982,00€CAY10566
CAS:CAY10566 is a potent SCD1 inhibitor, orally bioavailable, with IC50s: HepG2 cells, 7.9nM; mouse, 4.5nM; human, 26nM.Fórmula:C18H17ClFN5O2Pureza:99.54% - 99.75%Forma y color:SolidPeso molecular:389.81Ref: TM-T14878
1mg48,00€1mL*10mM (DMSO)112,00€5mg131,00€10mg195,00€25mg353,00€50mg505,00€100mg710,00€200mg954,00€Mycophenolic acid
CAS:Mycophenolic acid (Mycophenolate) is an inosine monophosphate dehydrogenase(IMPDH) inhibitor with anti-proliferative activity.Fórmula:C17H20O6Pureza:99.27% - 99.8%Forma y color:White SolidPeso molecular:320.3371LDH-IN-1
CAS:LDH-IN-1 is a pyrazole-based human lactate dehydrogenase (LDH) inhibitor(IC50s of 32 and 27 nM for LDHA and LDHB, respectively).Fórmula:C30H26N4O4S2Pureza:99.6%Forma y color:SolidPeso molecular:570.68Ref: TM-T11829
1mg178,00€5mg371,00€1mL*10mM (DMSO)467,00€10mg557,00€25mg888,00€50mg1.288,00€100mg1.693,00€200mg2.313,00€IDH-305
CAS:IDH-305: Oral, mutation-specific IDH1 inhibitor, 200x selective for R132 mutants; IC50: 27/28/6.14 nM for R132H/C/WT.Fórmula:C23H22F4N6O2Pureza:99.68%Forma y color:SolidPeso molecular:490.45CBR-5884
CAS:CBR-5884: active PHGDH inhibitor, IC50=33μM, disrupts serine synthesis, selectively targets high-serine cancers.Fórmula:C14H12N2O4S2Pureza:99.97%Forma y color:SolidPeso molecular:336.386NCT-502
CAS:NCT-502 (N-(4,6-dimethylpyridin-2-yl)-4-[5-(trifluoromethyl)pyridin-2-yl]piperazine-1-carbothioamide) is a human phosphoglycerate dehydrogenase inhibitor,Fórmula:C18H20F3N5SPureza:99.60%Forma y color:Yellow SolidPeso molecular:395.45Ref: TM-T16277
2mg37,00€5mg54,00€1mL*10mM (DMSO)59,00€10mg82,00€25mg150,00€50mg227,00€100mg394,00€500mg883,00€SCD1 inhibitor-4
CAS:SCD1 inhibitor-4 is stearoylCoA desaturase-1 (SCD1) inhibitor. SCD1 inhibitor-4 can be used for the research of diabetes.Fórmula:C17H16F3N5OPureza:99.71%Forma y color:SolidPeso molecular:363.34PTC299
CAS:PTC299 ((4-chlorophenyl) (1S)-6-chloro-1-(4-methoxyphenyl)-1,3,4,9-tetrahydropyrido[3,4-b]indole-2-carboxylate) is an orally active inhibitor of VEGFA mRNAFórmula:C25H20Cl2N2O3Pureza:99.72%Forma y color:White SolidPeso molecular:467.34Ref: TM-T12574
1mg111,00€5mg230,00€1mL*10mM (DMSO)236,00€10mg350,00€25mg590,00€50mg838,00€100mg1.144,00€Adrenosterone
CAS:Adrenosterone (11-ketoandrostenedione) is a steroid hormone isolated from the adrenal cortex.Fórmula:C19H24O3Pureza:98.13% - 98.29%Forma y color:SolidPeso molecular:300.39DHODH-IN-11
CAS:DHODH-IN-11 is a leflunomide derivative and weak dihydroorotate dehydrogenase (DHODH) inhibitor with a pKa of 5.03.Fórmula:C15H11N3O2Pureza:98.14%Forma y color:SolidPeso molecular:265.27BAY-2402234
CAS:BAY-2402234: a selective DHODH inhibitor targeting myeloid cancers with low-nanomolar potency.Fórmula:C21H18ClF5N4O4Pureza:98.9%Forma y color:SolidPeso molecular:520.84CVT-10216
CAS:CVT-10216 inhibits ALDH2 (IC50: 29 nM) and ALDH-1 (IC50: 1.3 μM), reducing alcohol intake and anxiety in rats.Fórmula:C24H19NO7SPureza:98.76%Forma y color:SolidPeso molecular:465.48GSK2837808A
CAS:GSK2837808A is a potent and selective inhibitor of lactate dehydrogenase A (LDHA) (IC50s: 1.9 and 14 nM for LDHA and LDHB, respectively).Fórmula:C31H25F2N5O7SPureza:99.78% - 99.78%Forma y color:SolidPeso molecular:649.62Ref: TM-T15435
1mg46,00€5mg105,00€1mL*10mM (DMSO)150,00€10mg167,00€25mg313,00€50mg432,00€100mg612,00€
