PDGF R beta/CD140b Protein, Human, Recombinant (His & Avi)
Ref. TM-TMPK-00421
1mg | 2.212,00 € | ||
100µg | 348,00 € | ||
500µg | 1.372,00 € |
Información del producto
- PDGFR1, CD140B, PDGFR-2, PDGF R β/CD140b, PDGF R beta, PDGFRB, PDGFR-β, JTK12, PDGFR, PDGF R β
PDGF is a major serum mitogen that can exist as a homo or hetero-dimeric protein consisting of disulfide-linked PDGF-A and PDGF-B chains. The PDGF-AA,PDGF-BB and PDGF-AB isoforms have been shown to bind to two distinct cell surface PDGF receptors with different affinities. Where as PDGF R alpha binds all three PDGF isoforms with high affinity, PDGF R beta binds PDGF-BB only with high-affinity. PDGF R plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. Plays a role in the migration of vascular smooth muscle cells and the formation of neointima at vascular injury sites.
Propiedades químicas
Consulta técnica sobre: TM-TMPK-00421 PDGF R beta/CD140b Protein, Human, Recombinant (His & Avi)
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