PDGFR
Los inhibidores del receptor del factor de crecimiento derivado de plaquetas (PDGFR) son compuestos que bloquean la señalización del PDGFR, un receptor involucrado en el crecimiento celular, la proliferación y la angiogénesis. El PDGFR desempeña un papel significativo en el desarrollo de los vasos sanguíneos que abastecen a los tumores. Inhibir el PDGFR puede, por lo tanto, prevenir la angiogénesis, lo que convierte a estos inhibidores en herramientas valiosas en la terapia contra el cáncer. En CymitQuimica, ofrecemos una selección de inhibidores de PDGFR de alta calidad para apoyar su investigación en oncología, biología vascular y angiogénesis.
Se han encontrado 130 productos para "PDGFR".
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GW 2580
CAS:Fórmula:C20H22N4O3Pureza:>98.0%(HPLC)Forma y color:White to Light yellow to Light orange powder to crystalPeso molecular:366.42Sorafenib Tosylate
CAS:Fórmula:C21H16ClF3N4O3·C7H8O3SPureza:>98.0%(T)(HPLC)Forma y color:White to Light yellow powder to crystalPeso molecular:637.03Imatinib Mesylate
CAS:Fórmula:C29H31N7O·CH4O3SPureza:>98.0%(HPLC)Forma y color:White to Light yellow powder to crystalPeso molecular:589.72Imatinib
CAS:Fórmula:C29H31N7OPureza:>98.0%(HPLC)Forma y color:White to Light yellow to Light orange powder to crystalPeso molecular:493.62TCS 359
CAS:Fórmula:C18H20N2O4SPureza:>98.0%(HPLC)Forma y color:Light yellow to Brown powder to crystalPeso molecular:360.43Dasatinib
CAS:Fórmula:C22H26ClN7O2SPureza:>95.0%(T)(HPLC)Forma y color:White to Light yellow powder to crystalPeso molecular:488.01Sunitinib Malate
CAS:Sunitinib Malate (Sunitinib) is an indolinone-based tyrosine kinase inhibitor.Fórmula:C26H33FN4O7Pureza:98% - 99.26%Forma y color:SolidPeso molecular:532.56Trapidil
CAS:Trapidil (Avantrin) is a coronary vasodilator agent.Fórmula:C10H15N5Pureza:99.42%Forma y color:White SolidPeso molecular:205.26Lenvatinib
CAS:Lenvatinib (E7080) is a multi-target receptor tyrosine kinase inhibitor that inhibits VEGFR1-3, FGFR1-4, KIT, PDGFR, and RET, and has oral activity.Fórmula:C21H19ClN4O4Pureza:98.46% - 99.96%Forma y color:White SolidPeso molecular:426.85Regorafénib N-oxyde (M2)
CAS:Regorafénib N-oxyde M2 is an active metabolite of Regorafenib.Fórmula:C21H15ClF4N4O4Pureza:98.03% - 98.26%Forma y color:White SolidPeso molecular:498.81N-Desmethyl imatinib
CAS:N-Desmethyl imatinib (Imatinib metabolite N-Desmethyl imatinib) is a metabolite of Imatinib, which is a multi-target inhibitor of c-Kit, v-Abl, and PDGFR.Fórmula:C28H29N7OPureza:98.60%Forma y color:SolidPeso molecular:479.58Ref: TM-T11641
1mg87,00€5mg166,00€1mL*10mM (DMSO)170,00€10mg303,00€25mg512,00€50mg737,00€100mg1.018,00€Olaratumab
CAS:Olaratumab(IMC-3G3) is a human monoclonal IgG1 antibody against platelet-derived growth factor receptor alpha (PDGFRα), which has antitumor effects and can bePureza:SDS-PAGE:95% SEC-HPLC:98.70%Forma y color:Transparent LiquidPeso molecular:147.12 kDaJNJ-10198409
CAS:JNJ-10198409: selective ATP competitive PDGF-RTK inhibitor; IC50: PDGFR-β 4.2 nM, PDGFR-α 45 nM; antiangiogenic & antiproliferative.Fórmula:C18H16FN3O2Pureza:98.51%Forma y color:Yellow SolidPeso molecular:325.34Ref: TM-T15616
1mg33,00€5mg92,00€1mL*10mM (DMSO)92,00€10mg122,00€25mg198,00€50mg294,00€100mg419,00€200mg587,00€2-(3,4-Dimethoxyphenylcarbamoyl)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide
CAS:Fórmula:C18H20N2O4SPureza:%Forma y color:SolidPeso molecular:360.4274Sunitinib
CAS:Sunitinib (SU 11248) is a multi-targeted receptor tyrosine kinase (RTK) inhibitor that inhibits VEGFR2 and PDGFRβ (IC50=80/2 nM).Fórmula:C22H27FN4O2Pureza:98% - 99.67%Forma y color:Yellow SolidPeso molecular:398.47Imatinib Mesylate
CAS:Imatinib Mesylate (STI-571) is a tyrosine kinase receptor inhibitor with antineoplastic activity (IC50s: 0.6 μM, 0.1 μM and 0.1 μM for v-Abl, c-Kit and PDGFR,Fórmula:C29H31N7O·CH4SO3Pureza:98% - >99.99%Forma y color:White SolidPeso molecular:589.714-[(4-Methyl-1-piperazinyl)methyl]-N-[4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]phenyl]benzamide
CAS:Fórmula:C29H31N7OPureza:98%Forma y color:SolidPeso molecular:493.6027AG 1295
CAS:AG 1295 is a selective PDGFR tyrosine-kinase inhibitor; it blocks PDGFR autophosphorylation without affecting EGF receptor.Fórmula:C16H14N2Pureza:99.93%Forma y color:SolidPeso molecular:234.3
![4-[(4-Methyl-1-piperazinyl)methyl]-N-[4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]phenyl]benz…](https://static.cymitquimica.com/products/IN/thumb-webp/DA00350H.webp)
