5-Aminotricyclo[3.3.1.13,7]decane-1,3-diol

CAS: 1382839-19-1

Ref. TR-A633195

Información del producto

• Nombre: 5-Aminotricyclo[3.3.1.13,7]decane-1,3-diol

Descripción

Applications 5-Aminotricyclo[3.3.1.13,7]decane-1,3-diol is an intermediate used in the synthesis of Hydroxy Vildagliptin (V305035), which is an impurity of Vildagliptin (V305000). Vildagliptin is a DPP-​4 enzyme inhibitor, has anti-oxidant properties and used as an apoptotic agent on pancreatic cancer . Vildagliptin is used to treat type 2 diabetes mellitus (T2DM) and improve the endothelial function of patients.
References Amritha, C.A., et al.: J. Clin. Diagn. Res., 9, FC14 (2015); Cosenso-Martin, L.N., et al.: Diabetol. Metab. Syndr., 7, 70/1 (2015)

• Marca: TRC

Propiedades químicas

• Peso molecular: 183.25
• Fórmula: C₁₀H₁₇NO₂
• Color/Forma: Neat
• InChI: InChI=1S/C10H17NO2/c11-8-1-7-2-9(12,4-8)6-10(13,3-7)5-8/h7,12-13H,1-6,11H2/t7-,8-,9+,10-
• Clave InChI: InChIKey=OTHKXWALZCWLGM-MSLAYNRJSA-N
• SMILES: N[C@]12C[C@@H]3C[C@](O)(C1)C[C@@](O)(C3)C2