5(S)-[1(S)-Azido-3(S)-[4-methoxy-3-(3-methoxypropoxy)benzyl]-4-methylpentyl]-3(S)-isopropyldihydrofuran-2-one

CAS: 324763-46-4

Ref. TR-A850300

Información del producto

• Nombre: 5(S)-[1(S)-Azido-3(S)-[4-methoxy-3-(3-methoxypropoxy)benzyl]-4-methylpentyl]-3(S)-isopropyldihydrofuran-2-one
• Sinónimos: (3S,5S)-5-[(1S,3S)-1-Azido-3-[[4-methoxy-3-(3-methoxypropoxy)phenyl]methyl]-4-methylpentyl]dihydro-3-(1-methylethyl)-2(3H)-furanone
• Marca: TRC

Descripción

Applications 5(S)-[1(S)-Azido-3(S)-[4-methoxy-3-(3-methoxypropoxy)benzyl]-4-methylpentyl]-3(S)-isopropyldihydrofuran-2-one is an intermediate in the preparation of orally active renin inhibitor Aliskiren (A536000).
References Wu, Y. et al.: Zhong. Yao. Dax. Xueb., 42, 400 (2011); Rueger, H. et al.: Tetrahed. Lett., 41, 10085 (2000);

Propiedades químicas

• Peso molecular: 461.59
• Fórmula: C₂₅H₃₉N₃O₅
• Color/Forma: Neat
• InChI: InChI=1S/C25H39N3O4/c1-16(2)20(13-18-9-10-23(31-6)19(12-18)8-7-11-30-5)14-22(27-28-26)24-15-21(17(3)4)25(29)32-24/h9-10,12,16-17,20-22,24H,7-8,11,13-15H2,1-6H3/t20-,21-,22-,24-/m0/s1
• SMILES: COCCCOc1cc(C[C@@H](C[C@H](N=[N+]=[N-])[C@@H]2C[C@@H](C(C)C)C(=O)O2)C(C)C)ccc1OC