2,3-Naphthalic Anhydride

CAS: 716-39-2

Ref. TR-N363000

Información del producto

• Nombre: 2,3-Naphthalic Anhydride
• Sinónimos: benzo[f][2]benzofuran-1,3-dione, 1,3-ββ-Isonaphthofurandione, 2,3-Naphthalenedicarboxylic acid anhydride, 2,3-Naphthalenedicarboxylic anhydride, 2,3-Naphthalic anhydride, Naphtho[2,3-C]Furan-1,3-Dione

Descripción

Stability Moisture Sensitive
Applications 2,3-Naphthalic anhydride is used as a reagent to synthesize analogues of Thalidomide (T338850), an inhibitor of tumour necrosis factor that was once abandoned because it caused birth defects, but is currently used as an inhibitor of angiogenesis in patients with multiple myeloma.
References D’Amato, R., et al.: Proc. Nat. Acad. Sci., 91, 4082 (1994); Ehrenpreis, E., et al.: Gastroenterology, 117, 1271 (1999); Parma, T., et al.: Nat. Med., 5, 582 (1999); Singhal, S., et al.: New Engl. J. Med., 341, 1565 (1999)

• Marca: TRC

Propiedades químicas

• Peso molecular: 198.17
• Fórmula: C₁₂H₆O₃
• Color/Forma: Neat
• InChI: InChI=1S/C12H6O3/c13-11-9-5-7-3-1-2-4-8(7)6-10(9)12(14)15-11/h1-6H
• Clave InChI: InChIKey=IZJDCINIYIMFGX-UHFFFAOYSA-N
• SMILES: O=C1OC(=O)c2cc3ccccc3cc21