CAS 1007786-48-2

JNK-IN-23

CAS : 1007786-48-2

JNK-IN-23 (Compound K12) is an inhibitor of JNK. It effectively inhibits the proliferation of MDA-MB-231 cells with a GIC50 of 30 nM. In vivo, JNK-IN-23 blocks metastatic growth of triple-negative breast cancer (TNBC). Additionally, it suppresses the growth of lung metastases by dual targeting of glutaminase-1 (GLS) and the pyruvate dehydrogenase complex (PDHC).

Formule : C₁₉H₁₈N₄OS₂

Couleur et forme : Solid

Masse moléculaire : 382.50

Ref: TM-T210950