CAS 101072-04-2

Formule : C14H11BrN4O3

InChI : InChI=1S/C14H11BrN4O3/c1-18-11-10(12(21)17-14(18)22)19(13(15)16-11)7-9(20)8-5-3-2-4-6-8/h2-6H,7H2,1H3,(H,17,21,22)

Code InChI : MDRUDFVHNBRYOO-UHFFFAOYSA-N

SMILES : CN1C2=C(C(=O)NC1=O)N(C(=N2)Br)CC(=O)C3=CC=CC=C3

8-Bromo-3-methyl-7-(2-oxo-2-phenylethyl)-1H-purine-2,6(3H,7H)-dione

Produit contrôlé

CAS : 101072-04-2

8-Bromo-3-methyl-7-(2-oxo-2-phenylethyl)-1H-purine-2,6(3H,7H)-dione is a glycidyl ester and alkylating agent that is used in the treatment of cancer. It is a prodrug that acts as a DNA crosslinker by reacting with DNA at the N7 position of guanine. This crosslink disrupts DNA replication and transcription and leads to cell death. 8-Bromo-3-methyl-7-(2 oxo 2 phenylethyl)-1H purine 2,6(3H,7H)-dione has been shown to be effective against myeloma cells but not against healthy cells.

Formule : C₁₄H₁₁BrN₄O₃

Degré de pureté : Min. 95%

Masse moléculaire : 363.17 g/mol

Ref: 3D-BEA07204