CAS 101264-90-8

Formule : C13H18N2O2

InChI : InChI=1S/C13H18N2O2/c1-2-3-4-9-13(17)15-14-10-11-7-5-6-8-12(11)16/h5-8,10,16H,2-4,9H2,1H3,(H,15,17)

Code InChI : ZXBABQFBOCLJFM-UHFFFAOYSA-N

SMILES : CCCCCC(=O)NN=CC1=CC=CC=C1O

Copper ionophore I

CAS : 101264-90-8

Copper ionophore I is an efficient carrier of copper ions that modulates intracellular copper levels to induce cuproptosis, with effects observed in cells such as 4T1 (IC₅₀= 0.45 μM) and MDA-MB-231 (IC₅₀= 1.21 μM). It elevates ROS, leading to mitochondrial dysfunction, and decreases the expression of proteins FDX1, DLAT, and LIAS. Additionally, it can activate immune-related pathways, enhancing T cell infiltration, making it a valuable compound for cancer research.

Formule : C₁₃H₁₈N₂O₂

Masse moléculaire : 234.3

Ref: TM-T213373