CAS 1032754-81-6

Formule : C21H28N8O3S2

InChI : InChI=1S/C21H28N8O3S2/c1-14-16(13-27-3-5-29(6-4-27)34(2,30)31)33-18-17(14)25-19(15-11-23-21(22)24-12-15)26-20(18)28-7-9-32-10-8-28/h11-12H,3-10,13H2,1-2H3,(H2,22,23,24)

Code InChI : AKKCGLXULFRAET-UHFFFAOYSA-N

SMILES : CC1=C(SC2=C1N=C(N=C2N3CCOCC3)C4=CN=C(N=C4)N)CN5CCN(CC5)S(=O)(=O)C

GNE-477

CAS : 1032754-81-6

GNE-477

Formule : C₂₁H₂₈N₈O₃S₂

Degré de pureté : ≥98%

Masse moléculaire : 504.63

Ref: 54-BUP02841

5-(7-Methyl-6-((4-(methylsulfonyl)piperazin-1-yl)methyl)-4-morpholinothieno[3,2-d]pyrimidin-2-yl)pyrimidin-2-amine

CAS : 1032754-81-6

Formule : C₂₁H₂₈N₈O₃S₂

Degré de pureté : 98%

Couleur et forme : Solid

Masse moléculaire : 504.6288

Ref: IN-DA008TGI

GNE-477

CAS : 1032754-81-6

Ref: 7W-GW3723

GNE-477

CAS : 1032754-81-6

GNE-477 is a potent and efficacious dual PI3K/mTOR inhibitor.

Formule : C₂₁H₂₈N₈O₃S₂

Degré de pureté : 98.88% - 99.55%

Couleur et forme : Solid

Masse moléculaire : 504.629

Ref: TM-T3692

GNE-477

CAS : 1032754-81-6

5-(7-Methyl-6-((4-(methylsulfonyl)piperazin-1-yl)methyl)-4-morpholinothieno[3,2-d]pyrimidin-2-yl)pyrimidin-2-amine

Formule : C₂₁H₂₈N₈O₃S₂

Degré de pureté : 99%

Masse moléculaire : 504.63

Ref: IN-DG556730

GNE-477

CAS : 1032754-81-6

GNE-477 is a small molecule with pharmacological properties that has been shown to inhibit the growth of cancer cells in vitro and in vivo. GNE-477 has been shown to inhibit autophagy, which may be responsible for its potent anticancer activity. GNE-477 also inhibits the activation of nuclear DNA and lipid kinase, inhibiting the production of proteins necessary for cell division. This drug is used to treat autoimmune diseases, skin cancer, and squamous carcinoma. GNE-477 also has anti-inflammatory properties that may be due to its inhibition of the epidermal growth factor receptor (EGFR).

Formule : C₂₁H₂₈N₈O₃S₂

Degré de pureté : Min. 95%

Masse moléculaire : 504.63 g/mol

Ref: 3D-HRB75481