CAS 1047645-82-8

Formule : C18H18Cl3FN4OS

InChI : InChI=1S/C18H17Cl2FN4OS.ClH/c1-25-16(14(19)9-23-25)13-7-15(27-17(13)20)18(26)24-12(8-22)6-10-3-2-4-11(21)5-10;/h2-5,7,9,12H,6,8,22H2,1H3,(H,24,26);1H/t12-;/m0./s1

Code InChI : YFQJOPFTGMHYNV-YDALLXLXSA-N

SMILES : CN1C(=C(C=N1)Cl)C2=C(SC(=C2)C(=O)N[C@@H](CC3=CC(=CC=C3)F)CN)Cl.Cl

GSK2110183B

CAS : 1047645-82-8

Formule : C₁₈H₁₈Cl₃FN₄OS

Degré de pureté : %

Couleur et forme : Solid

Masse moléculaire : 463.7841

Ref: IN-DA008TDB

Afuresertib hydrochloride

CAS : 1047645-82-8

Afuresertib hydrochloride

Formule : C₁₈H₁₈Cl₃FN₄OS

Degré de pureté : 99.5%

Masse moléculaire : 463.8

Ref: 54-BUP09723

Afuresertib hydrochloride

CAS : 1047645-82-8

Afuresertib hydrochloride is an inhibitor of Akt kinase (Kis of 0.08/2/2.6 nM for Akt1/Akt2/Akt3 respectively)

Formule : C₁₈H₁₈Cl₃FN₄OS

Degré de pureté : 99.96%

Couleur et forme : Solid

Masse moléculaire : 463.784

Ref: TM-T7885

Afuresertib HCl

CAS : 1047645-82-8

N-((S)-1-Amino-3-(3-fluorophenyl)propan-2-yl)-5-chloro-4-(4-chloro-1-methyl-1H-pyrazol-5-yl)thiophene-2-carboxamide hydrochloride

Formule : C₁₈H₁₈Cl₃FN₄OS

Degré de pureté : 98+%

Masse moléculaire : 463.78

Ref: IN-DG300977

Afuresertib hydrochloride

CAS : 1047645-82-8

Degré de pureté : 98+%

Masse moléculaire : 462.025

Ref: 10-F857573

Afuresertib hydrochloride

CAS : 1047645-82-8

Afuresertib hydrochloride is a small-molecule inhibitor, which is synthesized as a targeted therapeutic agent. It is specifically designed to inhibit the activity of AKT kinase, a crucial component in the PI3K/AKT/mTOR signaling pathway. This pathway is frequently deregulated in various cancers, contributing to tumor growth, survival, and resistance to conventional therapies.

Formule : C₁₈H₁₈Cl₃FN₄OS

Degré de pureté : Min. 95%

Masse moléculaire : 463.78 g/mol

Ref: 3D-XRB64582