CAS 1094048-77-7

Formule : C17H12INO5

InChI : InChI=1S/C17H12INO5/c1-24-15-6-9(5-12(18)17(15)23)4-11(8-19)16(22)10-2-3-13(20)14(21)7-10/h2-7,20-21,23H,1H3/b11-4+

Code InChI : HSRMHXWCTRFVHK-NYYWCZLTSA-N

SMILES : COC1=C(C(=CC(=C1)/C=C(\C#N)/C(=O)C2=CC(=C(C=C2)O)O)I)O

I-OMe-Tyrphostin AG 538

CAS : 1094048-77-7

I-OMe-Tyrphostin AG 538

Formule : C₁₇H₁₂INO₅

Degré de pureté : 98.5%

Masse moléculaire : 437.19

Ref: 54-BUP09174

I-OMe-Tyrphostin AG 538

CAS : 1094048-77-7

Formule : C₁₇H₁₂INO₅

Masse moléculaire : 437.1853

Ref: IN-DA024X6A

TYRPHOSTIN I-OME-AG 538

CAS : 1094048-77-7

2-(3,4-Dihydroxybenzoyl)-3-(4-hydroxy-3-iodo-5-methoxyphenyl)prop-2-enenitrile is a high purity ion channel inhibitor with IC50 of 1.8 nM. It has been shown to inhibit the activity of voltage gated sodium channels in rat hippocampal neurons and human erythrocytes. The binding affinity of 2-(3,4-dihydroxybenzoyl)-3-(4-hydroxy-3-iodo-5 methoxyphenyl)prop-2 enenitrile for the nicotinic acetylcholine receptor (nAChR), as determined by competitive radioligand binding assay, is 21 pM. This compound also inhibits the activity of potassium channels and has been shown to bind to peptides and antibodies.

Formule : C₁₇H₁₂INO₅

Degré de pureté : Min. 95%

Masse moléculaire : 437.18 g/mol

Ref: 3D-UTB04877

I-OMe-Tyrphostin AG 538

CAS : 1094048-77-7

I-OMe-Tyrphostin AG 538: IGF-1R & PI5P4Kα inhibitor, ATP-competitive, IC50 of 1 µM, targets IGF-1R pathway, cytotoxic in nutrient-poor PANC1 cells.

Formule : C₁₇H₁₂INO₅

Degré de pureté : 98.8%

Couleur et forme : Solid

Masse moléculaire : 437.1854

Ref: TM-T11593