CAS 1103500-20-4

Formule : C28H27Cl2N3O4

InChI : InChI=1S/C28H27Cl2N3O4/c1-32-14-20(28(34)35)19-8-7-17(13-24(19)32)33-11-9-18(10-12-33)36-15-21-26(31-37-27(21)16-5-6-16)25-22(29)3-2-4-23(25)30/h2-4,7-8,13-14,16,18H,5-6,9-12,15H2,1H3,(H,34,35)

Code InChI : RPVDFHPBGBMWID-UHFFFAOYSA-N

SMILES : CN1C=C(C2=C1C=C(C=C2)N3CCC(CC3)OCC4=C(ON=C4C5=C(C=CC=C5Cl)Cl)C6CC6)C(=O)O

LY2562175

CAS : 1103500-20-4

LY2562175 is an effective and selective FXR agonist (EC50: 193 nM).

Formule : C₂₈H₂₇Cl₂N₃O₄

Degré de pureté : 99.16% - 99.63%

Couleur et forme : Solid

Masse moléculaire : 540.438

Ref: TM-T15806

LY2562175

CAS : 1103500-20-4

LY2562175

Formule : C₂₈H₂₇Cl₂N₃O₄

Degré de pureté : ≥98%

Masse moléculaire : 540.44

Ref: 54-BUP08649

LY2562175

CAS : 1103500-20-4

Formule : C₂₈H₂₇Cl₂N₃O₄

Degré de pureté : 99%

Masse moléculaire : 540.4377

Ref: IN-DA01EOFV

LY2562175

CAS : 1103500-20-4

6-(4-((5-Cyclopropyl-3-(2,6-dichlorophenyl)isoxazol-4-yl)methoxy)piperidin-1-yl)-1-methyl-1H-indole-3-carboxylic acid

Formule : C₂₈H₂₇Cl₂N₃O₄

Degré de pureté : 99%

Masse moléculaire : 540.44

Ref: IN-DG01071364

LY2562175

Produit contrôlé

CAS : 1103500-20-4

Formule : C₂₈H₂₇Cl₂N₃O₄

Couleur et forme : Neat

Masse moléculaire : 540.438

Ref: TR-L490015

LY2562175

Produit contrôlé

CAS : 1103500-20-4

LY2562175 is a small molecule that inhibits diacylglycerol (DAG) production. It binds to the enzyme DAG kinase, which is responsible for catalyzing the phosphorylation of DAG to form phosphatidic acid. LY2562175 has been shown to reduce lipid levels in humans and improve dyslipidemia. LY2562175 also has inhibitory activity against primary sclerosing cholangitis, a chronic inflammatory condition of the bile ducts in the liver. The mechanism of action for this drug is not fully understood but it may be due to its ability to inhibit cell proliferation and the production of pro-inflammatory cytokines by immune cells. LY2562175 has undergone clinical trials as a diagnostic tool for primary sclerosing cholangitis and safety profiles have been evaluated in pharmacokinetic studies.

Formule : C₂₈H₂₇Cl₂N₃O₄

Degré de pureté : Min. 95%

Masse moléculaire : 540.44 g/mol

Ref: 3D-DUB50020