CAS 112022-83-0

(R)-2-Méthyl-CBS-oxazaborolidine

Formule : C₁₈H₂₀BNO

InChI : InChI=1S/C18H20BNO/c1-19-20-14-8-13-17(20)18(21-19,15-9-4-2-5-10-15)16-11-6-3-7-12-16/h2-7,9-12,17H,8,13-14H2,1H3/t17-/m1/s1

Code InChI : InChIKey=VMKAFJQFKBASMU-QGZVFWFLSA-N

SMILES : CB1OC([C@@]2(N1CCC2)[H])(C3=CC=CC=C3)C4=CC=CC=C4

Synonymes :

• (3AR)-1-methyl-3,3-diphenyl-3a,4,5,6-tetrahydropyrrolo[1,2-c][1,3,2]oxazaborole
• (3aR)-1-methyl-3,3-diphenyltetrahydro-3H-pyrrolo[1,2-c][1,3,2]oxazaborole
• (3aR)-Tetrahydro-1-methyl-3,3-diphenyl-1H,3H-pyrrolo[1,2-c][1,3,2]oxazaborole
• (R)-(+)-2-Methyl-CBS-oxazaborolindine
• (R)-1-Methyl,3,3-Diphenyl-TETRAHYDRO-PYRROLO(1,2-C)(1,3,2)oxazaborole
• (R)-1-Methyl-3,3-diphenylhexahydropyrrolo[1,2-c]-[1,3,2]oxazaborole
• (R)-3,3-Diphenyl-1-MethylTETRAHYDRO-1H,3H-PYRROLO[1,2-C][1,3,2]oxazaborole
• (R)-3,3-Diphenyl-1-MethylTETRAHYDRO-3H-PYRROLO-[1,2-C][1,3,2]oxazaborole
• (R)-3,3-Diphenyl-1-methylpyrrolidino[1,2-c]-1,3,2-oxazaborole
• (R)-5,5-Diphenyl-2-Methyl-3,4-PROPANO-1,3,2-oxazaborolidine
• (R)-Me-CBS
• (R)-Me-Corey-Bakshi-Shibata reagent
• (R)-Methyl oxazaborolidine
• (R)-Methyl-CBS
• (R)-Tetrahydro-1-methyl-3,3-diphenyl-1H,3H-pyrrolo[1,2-c][1,3,2]oxazaborole
• (R-Methyl-Corey-Bakshi-Shibata catalyst
• 1H,3H-Pyrrolo[1,2-c][1,3,2]oxazaborole, tetrahydro-1-methyl-3,3-diphenyl-, (3aR)-
• 1H,3H-Pyrrolo[1,2-c][1,3,2]oxazaborole, tetrahydro-1-methyl-3,3-diphenyl-, (R)-
• ALPHA,ALPHA-Diphenyl-D-PROLINOL METHYLBORONIC ACID CYCL-AMIDE-ESTER

(R)-5,5-Diphenyl-2-methyl-3,4-propano-1,3,2-oxazaborolidine (ca. 1mol/L in Toluene)

CAS : 112022-83-0

Formule : C₁₈H₂₀BNO

Couleur et forme : Colorless to Light yellow clear liquid

Masse moléculaire : 277.17

Ref: 3B-D5911

(R)-2-Methyl-CBS-oxazaborolidine, 1M soln. in toluene

CAS : 112022-83-0

(R)-2-Methyl-CBS-oxazaborolidine is used in the asymmetric reduction of prochiral ketones. Other applications include the enantioselective synthesis of -hydroxy acids, -amino acids, C2 symmetrical ferrocenyl diols, and propargyl alcohols. It is also used in a desymmetrizing reduction leading to (S)-

Formule : C₁₈H₂₀BNO

Couleur et forme : Clear colorless to yellow to orange, Liquid

Masse moléculaire : 277.17

Ref: 02-L14582

CALLERY™ (R)-Methyl oxazaborolidine, 1M in toluene

CAS : 112022-83-0

(R)-Tetrahydro-1-methyl-3,3-diphenyl-1H,3H-pyrrolo[1,2-c][1,3,2]oxazaborole, 0.9-1.1M in toluene [(R)-Methyloxazaborolidine] (R)-CBS Catalyst

Formule : C₁₈H₂₀BNO

Couleur et forme : colorless to amber liq.

Masse moléculaire : 277.17

Ref: 08-05-1000

(R)-1-methyl-3,3-diphenylhexahydropyrrolo[1,2-c][1,3,2]oxazaborole

CAS : 112022-83-0

Formule : C₁₈H₂₀BNO

Degré de pureté : 98%

Couleur et forme : Solid

Masse moléculaire : 277.1685

Ref: IN-DA00327K

(R)-Tetrahydro-1-methyl-3,3-diphenyl-1H,3H-pyrrolo[1,2-c][1,3,2]oxazaborole

CAS : 112022-83-0

(R)-Tetrahydro-1-methyl-3,3-diphenyl-1H,3H-pyrrolo[1,2-c][1,3,2]oxazaborole

Formule : C₁₈H₂₀BNO

Degré de pureté : 97%,99.5%ee

Couleur et forme : Solid

Masse moléculaire : 277.1685

Ref: 54-OR360007

(R)-(+)-2-Methyl-CBS-oxazaborolidine (1 M in Toluene)

Produit contrôlé

CAS : 112022-83-0

Formule : C₁₈H₂₀BNO

Couleur et forme : Single Solution

Masse moléculaire : 277.17

Ref: TR-M295200

(R)-5,5-Diphenyl-2-methyl-3,4-propano-1,3,2-oxazaborolidine

CAS : 112022-83-0

Formule : C₁₈H₂₀BNO

Degré de pureté : >97.0%(T)

Couleur et forme : White to Almost white powder to crystal

Masse moléculaire : 277.17

Ref: 3B-D2130

(R)-(+)-2-Methyl-CBS-oxazaborolidine

CAS : 112022-83-0

(R)-1-Methyl-3,3-diphenylhexahydropyrrolo[1,2-c][1,3,2]oxazaborole

Formule : C₁₈H₂₀BNO

Degré de pureté : 97% HPLC

Masse moléculaire : 277.17

Ref: IN-DG17551

(R)-Methyl oxazaborolidine 1M in toluene

CAS : 112022-83-0

Formule : C₂₅H₂₈BNO

Degré de pureté : 95.0%

Couleur et forme : Liquid, Clear

Masse moléculaire : 369.32

Ref: 10-F043435

(R)-(+)-2-Methyl-CBS-oxazaborolidine

CAS : 112022-83-0

(R)-(+)-2-Methyl-CBS-oxazaborolidine is a dpp-iv inhibitor that is a β-unsaturated ketone. It has been shown to inhibit the enzyme histone lysine demethylase, which may be involved in the regulation of bone mass. This compound also has a pharmacokinetic profile that is characterized by high oral bioavailability, low plasma protein binding, and rapid metabolism by liver enzymes. The reaction mechanism for this compound is based on the formation of an enolate carbanion. (R)-(+)-2-Methyl-CBS-oxazaborolidine can be synthesized with high stereoselectivity and yields from reactions with simple starting materials. This synthetic route also has a number of advantages over other methods: it does not require any protecting groups, it does not use toxic solvents such as dichloromethane or chloroform, and it can be performed in anhydrous conditions

Formule : C₁₈H₂₀BNO

Degré de pureté : Min. 95%

Couleur et forme : Solid

Masse moléculaire : 277.17 g/mol

Ref: 3D-FM163707

(R)-1-methyl-3,3-diphenylhexahydropyrrolo[1,2-c][1,3,2]oxazaborole

CAS : 112022-83-0

Degré de pureté : 98%, ee99%

Masse moléculaire : 277.1700134

Ref: 10-F862335