CAS 1196504-54-7

Formule : C16H21BrClN5O

InChI : InChI=1S/C16H20BrN5O.ClH/c17-11-6-19-15-13(14(11)22-5-1-2-10(18)8-22)12(7-20-15)21-16(23)9-3-4-9;/h6-7,9-10H,1-5,8,18H2,(H,19,20)(H,21,23);1H/t10-;/m1./s1

Code InChI : GKZACMRNGHGLEJ-HNCPQSOCSA-N

SMILES : C1C[C@H](CN(C1)C2=C3C(=CNC3=NC=C2Br)NC(=O)C4CC4)N.Cl

(R)-N-(4-(3-aminopiperidin-1-yl)-5-bromo-1H-pyrrolo[2,3-b]pyridin-3-yl)cyclopropanecarboxamide hydrochloride

CAS : 1196504-54-7

Degré de pureté : 95%

Ref: IN-DA000PFF

GDC0575 monohydrochloride

CAS : 1196504-54-7

GDC0575 monohydrochloride

Formule : C₁₆H₂₁BrClN₅O

Degré de pureté : ≥95%

Masse moléculaire : 414.73

Ref: 54-BUP07912

GDC0575 monohydrochloride

CAS : 1196504-54-7

GDC0575 (ARRY575), a potent Chk1 inhibitor, IC50 1.2nM, disrupts cell cycle arrest, allowing DNA repair before mitosis.

Formule : C₁₆H₂₁BrClN₅O

Degré de pureté : 97.85%

Couleur et forme : Solid

Masse moléculaire : 414.73

Ref: TM-T27407

GDC 0575 hydrochloride

CAS : 1196504-54-7

GDC 0575 is a potent and selective inhibitor of the N-type voltage-gated calcium channel. It binds to the ligand binding site of the channel and blocks the flow of calcium ions through these channels. This inhibits the release of neurotransmitters, leading to an anti-convulsant effect. GDC 0575 has also been shown to have activity as an activator, which increases intracellular calcium levels by blocking potassium channels.

Formule : C₁₆H₂₁BrClN₅O

Degré de pureté : Min. 95%

Masse moléculaire : 414.73 g/mol

Ref: 3D-FG172882