CAS 1235406-03-7

Benzenesulfonamide, 5-chloro-2-fluoro-4-[2-(4-pyridazinyl)-4-(trifluoromethyl)phenoxy]-N-1,3,4-thiadiazol-2-yl-

CAS : 1235406-03-7

Formule : C₁₉H₁₀ClF₄N₅O₃S₂

Degré de pureté : 99.37%

Masse moléculaire : 531.8910

Ref: IN-DA000KRI

PF-05186462

CAS : 1235406-03-7

PF-05186462

Formule : C₁₉H₁₀ClF₄N₅O₃S₂

Degré de pureté : ≥98%

Masse moléculaire : 531.89

Ref: 54-BUP00893

PF-05186462

CAS : 1235406-03-7

PF-05186462 (PF-05150122) is a potent, state-dependent, subtype selective Nav1.7 inhibitor with IC50 of 21 nM, no significant activity against Nav1.5.

Formule : C₁₉H₁₀ClF₄N₅O₃S₂

Degré de pureté : 99.10% - 99.37%

Couleur et forme : Yellow Solid

Masse moléculaire : 531.89

Ref: TM-T8711

PF-05186462

CAS : 1235406-03-7

PF-05186462 is a potent, selective and orally bioavailable small molecule inhibitor of the enzyme protein tyrosine phosphatase 1B (PTP1B). This enzyme is required for the activation of many downstream signaling pathways. PF-05186462 is being investigated for its potential as a therapeutic agent for treatment of diseases such as type 2 diabetes, Alzheimer's disease, and cancer.

Formule : C₁₉H₁₀ClF₄N₅O₃S₂

Degré de pureté : Min. 95%

Masse moléculaire : 531.9 g/mol

Ref: 3D-KZB40603