
CAS 1279829-87-6
:Formule :C17H12ClFN6O2S
InChI :InChI=1S/C17H12ClFN6O2S/c18-10-3-6-12(19)14(7-10)28(26,27)25-11-4-1-9(2-5-11)13-8-21-15-16(20)23-24-17(15)22-13/h1-8,25H,(H3,20,22,23,24)
Code InChI :DDKHTWASHUKHLD-UHFFFAOYSA-N
SMILES :C1=CC(=CC=C1C2=NC3=NNC(=C3N=C2)N)NS(=O)(=O)C4=C(C=CC(=C4)Cl)F
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SGK1-IN-1
CAS :SGK1-IN-1 is a ligand that binds to the receptor, G protein-coupled receptor kinase 1 (GRK1). It is a selective inhibitor of GRK1. SGK1 is involved in the regulation of ion channels, and thus may be used as a research tool for studying ion channel function. The binding of SGK1-IN-1 to GRK1 inhibits the phosphorylation of receptors and prevents the activation of downstream signaling pathways. This inhibition could be useful as an anti-inflammatory agent or in treating cardiac arrhythmias.
Formule :C17H12ClFN6O2SDegré de pureté :Min. 95%Masse moléculaire :418.8 g/molSGK1-IN-1
CAS :SGK1-IN-1 (compound 14n) is a highly potent SGK1 (Serum/Glucocorticoid Regulated Kinase 1) inhibitorFormule :C17H12ClFN6O2SDegré de pureté :97.44%Couleur et forme :SolidMasse moléculaire :418.833




