
CAS 1307896-46-3
:Formule :C24H26N4O5
InChI :InChI=1S/C24H26N4O5/c1-24(2,13-29)26-23(30)16(12-25)8-14-6-7-18-17(9-14)21(28-27-18)15-10-19(31-3)22(33-5)20(11-15)32-4/h6-11,29H,13H2,1-5H3,(H,26,30)(H,27,28)/b16-8+
Code InChI :FCCMYBKAZCDQGX-LZYBPNLTSA-N
SMILES :CC(C)(CO)NC(=O)/C(=C/C1=CC2=C(C=C1)NN=C2C3=CC(=C(C(=C3)OC)OC)OC)/C#N
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RMM 46
CAS :RMM 46 is a chemoproteomic inhibitor that selectively inhibits protein synthesis by reversibly covalently binding to the eukaryotic translation initiation factor 2A (eIF2A). This inhibitor has been shown to be non-catalytic and reversible, which means that it does not inhibit other protein kinases. The irreversible inhibition of the eIF2A by RMM 46 has been shown to result in a decrease in protein synthesis and a number of physiological effects including decreased granule size. RMM 46 has also been shown to have selectivity for the eIF2A over other protein kinases.Formule :C24H26N4O5Degré de pureté :Min. 95%Masse moléculaire :450.5 g/molRMM-46
CAS :RMM-46 is a reversible covalent inhibitor with high ligand efficiency and selectivity for MSK/RSK family kinases.Formule :C24H26N4O5Degré de pureté :98.15%Couleur et forme :Yellow SolidMasse moléculaire :450.49



