CAS 1310347-50-2

Formule : C18H14F3N5O2

InChI : InChI=1S/C18H14F3N5O2/c1-17(18(20,21)9-28-16(23)26-17)12-6-11(3-4-13(12)19)25-15(27)14-5-2-10(7-22)8-24-14/h2-6,8H,9H2,1H3,(H2,23,26)(H,25,27)/t17-/m1/s1

Code InChI : DVMUZHLUMHPCGZ-QGZVFWFLSA-N

SMILES : C[C@]1(C(COC(=N1)N)(F)F)C2=C(C=CC(=C2)NC(=O)C3=NC=C(C=C3)C#N)F

BACE1-IN-1

CAS : 1310347-50-2

BACE1-IN-1

Formule : C₁₈H₁₄F₃N₅O₂

Degré de pureté : 99.02%

Masse moléculaire : 389.33

Ref: 54-PC1032392

BACE1-IN-1

CAS : 1310347-50-2

Degré de pureté : 99.02%

Ref: IN-DA01EOCF

BACE1-IN-1

CAS : 1310347-50-2

BACE1-IN-1 is a peptide that has been shown to inhibit the activity of BACE1, a protein that is involved in the production of amyloid beta. Amyloid beta is a peptide involved in the formation of plaques in the brain that are responsible for Alzheimer's disease. BACE1-IN-1 blocks amyloid beta production by binding to BACE1 and preventing it from cleaving amyloid precursor protein (APP) into amyloid beta.

Formule : C₁₈H₁₄F₃N₅O₂

Degré de pureté : Min. 95%

Masse moléculaire : 389.3 g/mol

Ref: 3D-KCC34750

BACE1-IN-1

CAS : 1310347-50-2

BACE1-IN-1 is a high brain penetrant BACE1 inhibitor (IC50s: 32 and 47 nM for human BACE1 and BACE2).

Formule : C₁₈H₁₄F₃N₅O₂

Degré de pureté : 98%

Couleur et forme : Solid

Masse moléculaire : 389.3313

Ref: TM-T10450