
CAS 1349723-93-8
:Formule :C30H40Cl2N2O2
InChI :InChI=1S/C30H38N2O2.2ClH/c1-4-31-17-16-22-6-8-23(9-7-22)21-32(5-2)30-20-28(34-3)14-15-29(30)26-11-10-25-19-27(33)13-12-24(25)18-26;;/h6-9,12-15,19-20,26,31,33H,4-5,10-11,16-18,21H2,1-3H3;2*1H/t26-;;/m1../s1
Code InChI :XGFHYCAZOCBCRQ-FBHGDYMESA-N
SMILES :CCNCCC1=CC=C(C=C1)CN(CC)C2=C(C=CC(=C2)OC)[C@@H]3CCC4=C(C3)C=CC(=C4)O.Cl.Cl
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6 produits trouvés.
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Elacestrant dihydrochloride
CAS :Elacestrant dihydrochlorideFormule :C30H40Cl2N2O2Degré de pureté :99.5%Masse moléculaire :531.56Elacestrant dihydrochloride
CAS :Elacestrant dihydrochloride (DA-DKRAD1901 dihydrochloride) is an orally available selective estrogen receptor degrader with IC50s of 48 for ERα and 870 nM forFormule :C30H40Cl2N2O2Degré de pureté :99.59% - 99.99%Couleur et forme :SolidMasse moléculaire :531.557Elacestrant dihydrochloride
CAS :Produit contrôléElacestrant dihydrochloride is a potential drug for the treatment of breast cancer. This agent has been shown to inhibit the activity of CDK4/6, which are enzymes that regulate the cell cycle and prevent progression from G1 to S phase. Elacestrant dihydrochloride also causes apoptosis in tumor cells by binding to death receptors, causing them to trigger the release of proteins that activate apoptosis. The uptake of elacestrant dihydrochloride into tumor cells is increased by epidermal growth factor (EGF) and other receptor binding drugs. A study found that elacestrant dihydrochloride at a dose of 100 mg/kg was effective in reducing tumor growth in xenograft mice models when combined with palbociclib.
Formule :C30H40Cl2N2O2Degré de pureté :Min. 95%Masse moléculaire :531.56 g/mol





