CAS 1393465-84-3

Formule : C24H22F2N6O3S

InChI : InChI=1S/C24H22F2N6O3S/c1-3-32(2)36(34,35)31-19-7-6-18(25)20(21(19)26)22(33)17-12-30-24-16(17)8-14(9-29-24)15-10-27-23(28-11-15)13-4-5-13/h6-13,31H,3-5H2,1-2H3,(H,29,30)

Code InChI : DKNZQPXIIHLUHU-UHFFFAOYSA-N

SMILES : CCN(C)S(=O)(=O)NC1=C(C(=C(C=C1)F)C(=O)C2=CNC3=C2C=C(C=N3)C4=CN=C(N=C4)C5CC5)F

N'-[3-[[5-(2-Cyclopropyl-5-pyrimidinyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]carbonyl]-2,4-difluorophenyl]-N-ethyl-N-methylsulfamide

CAS : 1393465-84-3

Formule : C₂₄H₂₂F₂N₆O₃S

Degré de pureté : %

Masse moléculaire : 512.5317

Ref: IN-DA001ASS

PLX 7904

CAS : 1393465-84-3

Formule : C₂₄H₂₂F₂N₆O₃S

Masse moléculaire : 512.54

Ref: 4Z-P-498002

PLX7904

CAS : 1393465-84-3

PLX7904 is a small molecule that binds to the active site of DNA polymerase alpha and inhibits its activity. It has been shown to inhibit the production of suppressor genes in human cells, which may be responsible for the suppression of autoimmune diseases and cancer. PLX7904 also has an effect on probiotic bacteria by binding to iron, which is necessary for their survival. PLX7904 can bind to a variety of molecules through hydrogen bonds, including DNA and iron-containing proteins. This drug has been shown to have synergistic effects with other drugs when used in cell culture studies.

Formule : C₂₄H₂₂F₂N₆O₃S

Degré de pureté : Min. 95%

Masse moléculaire : 512.53 g/mol

Ref: 3D-TFC46584

PLX7904

CAS : 1393465-84-3

PLX7904 (PB04), a selective RAF inhibitor, blocks ERK1/2 in mutant BRAF melanoma without activating it in RAS mutants.

Formule : C₂₄H₂₂F₂N₆O₃S

Degré de pureté : 99.51% - 99.66%

Couleur et forme : Solid

Masse moléculaire : 512.532

Ref: TM-T6949