
CAS 1413431-07-8
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6 produits trouvés.
N-(2-(tert-Butyl)-5-hydroxy-4-(2-(methyl-d3)propan-2-yl-1,1,1,3,3,3-d6)phenyl)-4-oxo-1,4-dihydroquinoline-3-carboxamide
CAS :N-(2-(tert-Butyl)-5-hydroxy-4-(2-(methyl-d3)propan-2-yl-1,1,1,3,3,3-d6)phenyl)-4-oxo-1,4-dihydroquinoline-3-carboxamideFormule :C24H19D9N2O3Degré de pureté :99.83%Masse moléculaire :401.55Ivacaftor (4-tertbutyl-d9) (Major)
CAS :Produit contrôléFormule :C24H19D9N2O3Couleur et forme :NeatMasse moléculaire :401.55Ivacaftor-D9
CAS :Ivacaftor-D9 is a deuterated compound of ivacaftor used for isotope tracing. Ivacaftor is an effective, orally administered CFTR modulator, cystic fibrosis.Formule :C24H19D9N2O3Degré de pureté :99.13%Couleur et forme :White SolidMasse moléculaire :401.55Ivacaftor (4-tertbutyl-d9) (major)
CAS :Ivacaftor is a drug substance with the molecular formula C17H20Cl2O3, a monocarboxylic acid amide. Ivacaftor is indicated as a treatment for cystic fibrosis (CF) in patients age 12 years and older who have one of the following mutations: G551D, G1244E, G1349D, G178R, G551S, S1251N, S1255P, S549N or R117C. Ivacaftor binds to and activates the CFTR protein by increasing its stability and function. The carboxyl terminal domain of CFTR is required for interaction with ivacaftor. Ivacaftor also potentiates the activity of chromenes such as ivacaftor (4-tertbutyl-d9) and other cftr potentiators such as VX-770. These compounds are being studied in cancer treatment because they may be able toFormule :C24H28N2O3Degré de pureté :Min. 95%Masse moléculaire :401.5 g/mol





