CAS 1445879-21-9
:Formule :C31H25F2N5O7S
InChI :InChI=1S/C31H25F2N5O7S/c1-43-29-25(14-35-31(37-29)44-2)16-3-6-24-26(9-16)34-15-27(46(41,42)38-20-4-5-20)28(24)36-21-7-17(30(39)40)8-22(13-21)45-23-11-18(32)10-19(33)12-23/h3,6-15,20,38H,4-5H2,1-2H3,(H,34,36)(H,39,40)
Code InChI :RZBCPMYJIARMGV-UHFFFAOYSA-N
SMILES :COC1=NC(=NC=C1C2=CC3=NC=C(C(=C3C=C2)NC4=CC(=CC(=C4)C(=O)O)OC5=CC(=CC(=C5)F)F)S(=O)(=O)NC6CC6)OC
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10 produits trouvés.
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GSK2837808A
CAS :GSK2837808A is a potent and selective inhibitor of lactate dehydrogenase A (LDHA) (IC50s: 1.9 and 14 nM for LDHA and LDHB, respectively).Formule :C31H25F2N5O7SDegré de pureté :99.78% - 99.78%Couleur et forme :SolidMasse moléculaire :649.62Ref: TM-T15435
1mg46,00€5mg105,00€1mL*10mM (DMSO)150,00€10mg167,00€25mg313,00€50mg432,00€100mg612,00€3-((3-(N-Cyclopropylsulfamoyl)-7-(2,4-Dimethoxypyrimidin-5-Yl)Quinolin-4-Yl)Amino)-5-(3,5-Difluorophenoxy)Benzoic Acid
CAS :3-((3-(N-Cyclopropylsulfamoyl)-7-(2,4-Dimethoxypyrimidin-5-Yl)Quinolin-4-Yl)Amino)-5-(3,5-Difluorophenoxy)Benzoic AcidFormule :C31H25F2N5O7SDegré de pureté :98%Masse moléculaire :649.62GSK2837808A
CAS :Formule :C31H25F2N5O7SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :649.6213GSK2837808A
CAS :3-((3-(N-Cyclopropylsulfamoyl)-7-(2,4-dimethoxypyrimidin-5-yl)quinolin-4-yl)amino)-5-(3,5-difluorophenoxy)benzoic acidFormule :C31H25F2N5O7SDegré de pureté :98%Masse moléculaire :649.623-((3-(N-Cyclopropylsulfamoyl)-7-(2,4-dimethoxypyrimidin-5-yl)quinolin-4-yl)amino)-5-(3,5-difluorophenoxy)benzoic acid
CAS :Degré de pureté :98%Masse moléculaire :649.6300049GSK 2837808A
CAS :GSK 2837808A is a small molecule that inhibits mitochondrial respiration and ATP synthesis. It binds to the mitochondrial receptor, which is found on the outer membrane of mitochondria. GSK 2837808A has been shown to inhibit tumor growth in deficient mice and human cancer cells, due to its ability to induce apoptosis by activating caspase-1. Inhibition of mitochondrial respiration may also have an effect on cellular energy metabolism, as well as epithelial mesenchymal transition. GSK 2837808A has also been shown to inhibit glutamate dehydrogenase, which can lead to decreased production of neurotransmitters such as dopamine and serotonin. GSK 2837808A also inhibits aerobic glycolysis in cancer cells, leading to a decrease in glucose uptake.
Degré de pureté :Min. 95%
