CAS 14937-32-7
:Penta-O-galloyl-β-D-glucose
Description :
Penta-O-galloyl-β-D-glucose est un composé polyphénolique dérivé du glucose, caractérisé par la présence de cinq groupes galloyles estérifiés aux groupes hydroxyles de la molécule de glucose. Ce composé présente de fortes propriétés antioxydantes, attribuées à la présence de plusieurs groupes hydroxyles phénoliques capables de piéger les radicaux libres. Penta-O-galloyl-β-D-glucose est connu pour ses potentiels bienfaits pour la santé, y compris des activités anti-inflammatoires, antimicrobiennes et anticancéreuses, ce qui en fait un sujet d'intérêt dans la recherche pharmacologique et nutraceutique. Sa solubilité est généralement plus élevée dans les solvants organiques par rapport à l'eau, ce qui peut influencer sa biodisponibilité et son application dans diverses formulations. La stabilité du composé peut être affectée par des facteurs tels que le pH et la température, qui sont des considérations importantes dans son stockage et son utilisation. De plus, sa complexité structurelle contribue à ses interactions uniques avec les systèmes biologiques, renforçant encore son potentiel en tant qu'agent thérapeutique. Dans l'ensemble, Penta-O-galloyl-β-D-glucose représente un domaine d'étude significatif dans le domaine des produits naturels et de la chimie médicinale.
Formule :C41H32O26
InChI :InChI=1S/C41H32O26/c42-17-1-12(2-18(43)28(17)52)36(57)62-11-27-33(64-37(58)13-3-19(44)29(53)20(45)4-13)34(65-38(59)14-5-21(46)30(54)22(47)6-14)35(66-39(60)15-7-23(48)31(55)24(49)8-15)41(63-27)67-40(61)16-9-25(50)32(56)26(51)10-16/h1-10,27,33-35,41-56H,11H2/t27-,33-,34+,35-,41+/m1/s1
Code InChI :InChIKey=QJYNZEYHSMRWBK-NIKIMHBISA-N
SMILES :O(C(=O)C1=CC(O)=C(O)C(O)=C1)[C@@H]2[C@@H](OC(=O)C3=CC(O)=C(O)C(O)=C3)[C@H](OC(=O)C4=CC(O)=C(O)C(O)=C4)O[C@H](COC(=O)C5=CC(O)=C(O)C(O)=C5)[C@H]2OC(=O)C6=CC(O)=C(O)C(O)=C6
Synonymes :- 1,2,3,4,6-O-Pentagalloylglucose
- 1,2,3,4,6-Penta-O-Galloyl-B-D-Glucopyranose
- 1,2,3,4,6-Penta-O-galloyl-β-<span class="text-smallcaps">D</span>-glucopyranose
- 1,2,3,4,6-Penta-O-galloyl-β-<span class="text-smallcaps">D</span>-glucopyranoside
- 1,2,3,4,6-Penta-O-galloyl-β-<span class="text-smallcaps">D</span>-glucose
- 1,2,3,4,6-Penta-O-galloyl-β-<span class="text-smallcaps">D</span>-glucoside
- 1,2,3,4,6-Penta-O-galloyl-β-glucopyranose
- 1,2,3,4,6-Penta-O-galloylglucose
- 1,2,3,4,6-Pentagalloyl-β-<span class="text-smallcaps">D</span>-glucopyranose
- 1,2,3,4,6-Pentagalloyl-β-<span class="text-smallcaps">D</span>-glucopyranoside
- 1,2,3,4,6-Pentagalloyl-β-<span class="text-smallcaps">D</span>-glucose
- 1,2,3,4,6-Pentagalloylglucose
- 1,2,3,4,6-pentakis-O-(3,4,5-trihydroxybenzoyl)-beta-D-glucopyranose
- Db 03208
- G 7548
- Gallic acid, pentaester with β-<span class="text-smallcaps">D</span>-glucopyranose
- Gallotannin 15
- Glucopyranose, pentagallate, β-<span class="text-smallcaps">D</span>-
- PGG
- Penta-O-galloyl-β-<span class="text-smallcaps">D</span>-glucopyranose
- Penta-O-galloyl-β-<span class="text-smallcaps">D</span>-glucose
- Penta-O-galloylglucose
- Penta-Ortho-Galloylglucose
- Pentagalloyl Glucose
- Pentagalloyl-<span class="text-smallcaps">D</span>-glucose
- Pentagalloylglucose
- beta-penta-O-galloyl-glucose
- β-1,2,3,4,6-Pentagalloylglucose
- β-<span class="text-smallcaps">D</span>-Glucopyranose, 1,2,3,4,6-pentakis(3,4,5-trihydroxybenzoate)
- β-<span class="text-smallcaps">D</span>-Glucopyranose, pentakis(3,4,5-trihydroxybenzoate)
- Glucopyranose, pentagallate, β-D-
- β-D-Glucopyranose, 1,2,3,4,6-pentakis(3,4,5-trihydroxybenzoate)
- 1,2,3,4,6-Pentagalloyl-β-D-glucose
- β-D-Glucopyranose, pentakis(3,4,5-trihydroxybenzoate)
- Voir plus de synonymes
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(2S,3R,4S,5R,6R)-6-(((3,4,5-Trihydroxybenzoyl)Oxy)Methyl)Tetrahydro-2H-Pyran-2,3,4,5-Tetrayl Tetrakis(3,4,5-Trihydroxybenzoate)
CAS :(2S,3R,4S,5R,6R)-6-(((3,4,5-Trihydroxybenzoyl)Oxy)Methyl)Tetrahydro-2H-Pyran-2,3,4,5-Tetrayl Tetrakis(3,4,5-Trihydroxybenzoate)Formule :C41H32O26Degré de pureté :98%Masse moléculaire :940.68Pentagalloylglucose
CAS :PentagalloylglucoseFormule :C41H32O26Degré de pureté :≥98%Couleur et forme :SolidMasse moléculaire :940.681,2,3,4,6-Penta-O-galloyl-β-D-glucopyranose
CAS :Formule :C41H32O26Degré de pureté :(HPLC) ≥ 98.0%Couleur et forme :White to yellow or light brown powderMasse moléculaire :940.68β-D-Glucopyranose, 1,2,3,4,6-pentakis(3,4,5-trihydroxybenzoate)
CAS :Formule :C41H32O26Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :940.6772Pentagalloylglucose (Standard)
CAS :Pentagalloylglucose (Standard) is a reference standard for research and analysis in studies involving Pentagalloylglucose. 1, 2, 3, 4, 6-Pentagalloylglucose (Penta-O-galloyl-β-D-glucose) and gallic acid from Pistacia lentiscus have antimutagenic and antioxidant activities. 2. 1, 2, 3, 4, 6-Penta-O-galloyl-beta-D-glucose (PGG) possesses potent anti-proliferative and anti-invasive effects, it also has inhibition of inducible nitric oxide synthase and cyclooxygenase-2 activity. 3. PGG may serve as a model for the development of new types of anti-diabetic and anti-metabolic syndrome therapeutics. 4. 1, 2, 3, 4, 6-Penta- O -galloyl-β- d -glucose has vasodilatory and anti-inflammatory effects, it dilates vascular smooth muscle and suppresses the vascular inflammatory process via endothelium-dependent nitric oxide (NO)/cGMP signaling. 5. 1, 2, 3, 4, 6-Penta-O-galloyl-beta-D-glucose can decrease the level of extracellular hepatitis B virus (HBV) (IC5, 1. microg/ml) in a dose-dependent manner, it also can reduce the HBsAg level by 25% at a concentration of 4 microg/ml; the gallate structure of PGG may play a critical role in the inhibition of anti-HBV activity, suggests that PGG could be a candidate for developing an anti-HBV agent. 6. 1, 2, 3, 4, 6-Penta-O-galloyl-β-D-glucose has anti-parasitic activity, displays an EC5 value of 67 μM, at least 6.6-fold more effective than the standard drug benznidazole against trypomastigote forms of T. cruzi.Formule :C41H32O26Masse moléculaire :940.67721,2,3,4,6-Penta-O-galloyl-b-D-glucopyranose (>85%)
CAS :Produit contrôléStability Hygroscopic, Temperature Sensitive
Applications Found to exhibit in vitro growth-inhibiting effect on human hepatocellular carcinoma cell line, SK-HEP-1 cells.
References Oh, G-S, et al.: Cancer Letters, 174, 17 ( 2001)Formule :C41H32O26Degré de pureté :>85%Couleur et forme :NeatMasse moléculaire :940.681,2,3,4,6-O-pentagalloylglucose
CAS :(2S,3R,4S,5R,6R)-6-(((3,4,5-Trihydroxybenzoyl)oxy)methyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetrakis(3,4,5-trihydroxybenzoate)Formule :C41H32O26Degré de pureté :98%Masse moléculaire :940.68Pentagalloylglucose
CAS :1, 2, 3, 4, 6-Pentagalloylglucose (Penta-O-galloyl-β-D-glucose) and gallic acid from Pistacia lentiscus have antimutagenic and antioxidant activities.Formule :C41H32O26Degré de pureté :99.17% - 99.97%Couleur et forme :Gray SolidMasse moléculaire :940.67721,2,3,4,6-Pentagalloyl β-D-glucose
CAS :Natural glycosideFormule :C41H32O26Degré de pureté :≥ 90.0 % (HPLC)Couleur et forme :PowderMasse moléculaire :940.691,2,3,4,6-Penta-O-galloyl-β-D-glucopyranose
CAS :A gallotannin found in plants, with various biological activities. Its anti-cancer effect has been demonstrated in several cancer cell lines, mediated by inhibition of DNA replication, proliferation and angiogenesis. Elicits anti-inflammatory, antioxidative and anti-diabetic effects. Recently, it has been identified as an inhibitor of c-Myc in hepatocellular carcinoma and multiple myeloma cells.Formule :C41H32O26Degré de pureté :Min. 96 Area-%Couleur et forme :PowderMasse moléculaire :940.68 g/molPentagalloylglucose - Bio-X ™
CAS :A gallotannin found in plants, with various biological activities. Its anti-cancer effect has been demonstrated in several cancer cell lines, mediated by inhibition of DNA replication, proliferation and angiogenesis. Elicits anti-inflammatory, antioxidative and anti-diabetic effects. Recently, it has been identified as an inhibitor of c-Myc in hepatocellular carcinoma and multiple myeloma cells.Formule :C41H32O26Degré de pureté :Min. 98 Area-%Couleur et forme :PowderMasse moléculaire :940.68 g/mol
