CAS 1606974-33-7

Formule : C21H15ClF3NO2

InChI : InChI=1S/C21H15ClF3NO2/c22-17-3-1-2-16(12-17)18-9-15(10-19(26-18)21(23,24)25)8-13-4-6-14(7-5-13)11-20(27)28/h1-7,9-10,12H,8,11H2,(H,27,28)

Code InChI : LTSUMTMGJHPGFX-UHFFFAOYSA-N

SMILES : C1=CC(=CC(=C1)Cl)C2=NC(=CC(=C2)CC3=CC=C(C=C3)CC(=O)O)C(F)(F)F

Zatolmilast

CAS : 1606974-33-7

Zatolmilast (BPN14770) is an allosteric inhibitor of selective phosphodiesterase 4D (PDE4D; IC50s: 7.8 nM and 7.4 nM for PDE4D7 and PDE4D3).

Formule : C₂₁H₁₅ClF₃NO₂

Degré de pureté : 98.20%

Couleur et forme : Solid

Masse moléculaire : 405.798

Ref: TM-T10590

Zatolmilast

CAS : 1606974-33-7

Zatolmilast

Formule : C₂₁H₁₅ClF₃NO₂

Degré de pureté : ≥98%

Masse moléculaire : 405.8

Ref: 54-BUP07048

Zatolmilast

CAS : 1606974-33-7

2-(4-((2-(3-Chlorophenyl)-6-(trifluoromethyl)pyridin-4-yl)methyl)phenyl)acetic acid

Formule : C₂₁H₁₅ClF₃NO₂

Degré de pureté : 99%

Masse moléculaire : 405.8

Ref: IN-DG01110804

Zatolmilast

Produit contrôlé

CAS : 1606974-33-7

Formule : C₂₁H₁₅ClF₃NO₂

Couleur et forme : Neat

Masse moléculaire : 405.798

Ref: TR-Z213475

BPN14770

CAS : 1606974-33-7

BPN14770 is a natural product that has been shown to have anti-inflammatory properties. This compound inhibits the release of intracellular calcium, which may be due to its ability to inhibit the conversion of dehydroascorbic acid (DHA) to ascorbic acid in cells. BPN14770 also has an immunosuppressive effect on wild-type mice and induces a significant decrease in camp levels. In vitro studies show that this compound binds with high affinity to cell surface receptors, including growth factor receptor tyrosine kinase and transferrin receptor, which are involved in uptake and trafficking of proteins. Studies have shown that BPN14770 has low potency against pharmacological agents and clinical studies are still needed to evaluate its pharmacokinetic properties.

Formule : C₂₁H₁₅ClF₃NO₂

Degré de pureté : Min. 95%

Masse moléculaire : 405.8 g/mol

Ref: 3D-GPC97433