CAS 1677667-24-1

Formule : C22H12ClF3N2O4

InChI : InChI=1S/C22H12ClF3N2O4/c23-14-5-3-4-13(22(24,25)26)17(14)19(30)20-27-18(15-6-1-2-9-28(15)20)11-7-8-12(21(31)32)16(29)10-11/h1-10,29H,(H,31,32)

Code InChI : UAAUZNSONHHQQI-UHFFFAOYSA-N

SMILES : C1=CC2=C(N=C(N2C=C1)C(=O)C3=C(C=CC=C3Cl)C(F)(F)F)C4=CC(=C(C=C4)C(=O)O)O

GNE-0946

CAS : 1677667-24-1

GNE-0946

Formule : C₂₂H₁₂ClF₃N₂O₄

Degré de pureté : ≥98%

Masse moléculaire : 460.79

Ref: 54-BUP23167

GNE-0946

CAS : 1677667-24-1

Formule : C₂₂H₁₂ClF₃N₂O₄

Degré de pureté : 98.09%

Masse moléculaire : 460.7899

Ref: IN-DA027JF8

4-[3-[2-Chloro-6-(trifluoromethyl)benzoyl]imidazo[1,5-a]pyridin-1-yl]-2-hydroxybenzoic acid

CAS : 1677667-24-1

4-[3-[2-Chloro-6-(trifluoromethyl)benzoyl]imidazo[1,5-a]pyridin-1-yl]-2-hydroxybenzoic acid is a potent inhibitor of antibody production and is used as a research tool for cell biology, peptides, pharmacology, and ion channels. This compound binds to the ATP binding site of the enzyme protein kinase A (PKA), inhibiting both cAMP-dependent and independent pathways. 4-[3-[2-Chloro-6-(trifluoromethyl)benzoyl]imidazo[1,5-a]pyridin-1-yl]-2-hydroxybenzoic acid also blocks ion channel function by binding to the voltage sensor domain of potassium channels. It has been shown to inhibit receptor function in vitro.

Formule : C₂₂H₁₂ClF₃N₂O₄

Degré de pureté : Min. 95%

Masse moléculaire : 460.8 g/mol

Ref: 3D-CSC66724

GNE-0946

CAS : 1677667-24-1

GNE-0946 is an effective and selective RORγ/RORc/NR1F3 antagonist (inverse agonist) with an EC50 of 4 nM in HEK-293 cells. autoimmune disease research.

Formule : C₂₂H₁₂ClF₃N₂O₄

Degré de pureté : 98.11%

Couleur et forme : Solid

Masse moléculaire : 460.79

Ref: TM-T15398