CAS 1698878-14-6

Formule : C20H25N3O5S

InChI : InChI=1S/C20H25N3O5S/c1-20(2,25)14-29(26,27)22-17-6-5-16-12-23(9-7-15(16)10-17)19(24)13-28-18-4-3-8-21-11-18/h3-6,8,10-11,22,25H,7,9,12-14H2,1-2H3

Code InChI : QHHSCLARESIWBH-UHFFFAOYSA-N

SMILES : CC(C)(CS(=O)(=O)NC1=CC2=C(CN(CC2)C(=O)COC3=CN=CC=C3)C=C1)O

Nampt-IN-1

CAS : 1698878-14-6

Nampt-IN-1

Formule : C₂₀H₂₅N₃O₅S

Degré de pureté : 99%

Masse moléculaire : 419.49

Ref: 54-BUP09433

Nampt-IN-1

CAS : 1698878-14-6

Formule : C₂₀H₂₅N₃O₅S

Degré de pureté : 99%

Masse moléculaire : 419.4946

Ref: IN-DA00ABOK

2-Hydroxy-2-methyl-N-(2-(2-(pyridin-3-yloxy)acetyl)-1,2,3,4-tetrahydroisoquinolin-6-yl)propane-1-sulfonamide

CAS : 1698878-14-6

2-Hydroxy-2-methyl-N-(2-(2-(pyridin-3-yloxy)acetyl)-1,2,3,4-tetrahydroisoquinolin-6-yl)propane-1-sulfonamide

Formule : C₂₀H₂₅N₃O₅S

Degré de pureté : 99%

Masse moléculaire : 419.49

Ref: IN-DG630431

Nampt-IN-1

CAS : 1698878-14-6

Nampt-IN-1 (LSN3154567) (LSN3154567) is a potent and selective NAMPT inhibitor. Nampt-IN-1 inhibits purified NAMPT with an IC50 of 3.1 nM.

Formule : C₂₀H₂₅N₃O₅S

Degré de pureté : 99.28% - 99.4%

Couleur et forme : Solid

Masse moléculaire : 419.495

Ref: TM-T4376

LSN 3154567 (Nampt-IN-1)

CAS : 1698878-14-6

Formule : C₂₀H₂₅N₃O₅S

Masse moléculaire : 419.50

Ref: 4Z-L-182001

LSN 3154567

CAS : 1698878-14-6

Nicotinamide phosphoribosyl transferase (NAMPT) competitive inhibitor with IC50 = 3.1 nM. A major consequence of NAMPT inhibition is the attenuation of glycolysis at the GADPH step because this enzyme requires NAD+ for activity. The compound exhibits broad spectrum anti-cancer activity and significant tumor regression was observed in vitro. Although retinal and haematological toxicity has been associated with NAMPT inhibitors, LSN 3154567 does not lead to retinopathy in rats and can be mitigated with co-administration of nicotinic acid.

Formule : C₂₀H₂₅N₃O₅S

Degré de pureté : Min. 95%

Couleur et forme : Powder

Masse moléculaire : 419.5 g/mol

Ref: 3D-BL165041

Nampt-IN-1

CAS : 1698878-14-6

Formule : C₂₀H₂₅N₃O₅S

Masse moléculaire : 419.5

Ref: BE-RMCL149001

Nampt-IN-1

Produit contrôlé

CAS : 1698878-14-6

Formule : C₂₀H₂₅N₃O₅S

Couleur et forme : Neat

Masse moléculaire : 398.361

Ref: TR-N285780