CAS 1784252-84-1

Formule : C27H43Cl2N5O2

InChI : InChI=1S/C27H41N5O2.2ClH/c1-33-24-18-22-23(19-25(24)34-2)29-27(30-26(22)28-20-10-6-3-4-7-11-20)32-16-12-21(13-17-32)31-14-8-5-9-15-31;;/h18-21H,3-17H2,1-2H3,(H,28,29,30);2*1H

Code InChI : GKJKNYQUFAPLOQ-UHFFFAOYSA-N

SMILES : COC1=C(C=C2C(=C1)C(=NC(=N2)N3CCC(CC3)N4CCCCC4)NC5CCCCCC5)OC.Cl.Cl

C-021 dihydrochloride

CAS : 1784252-84-1

C-021 dihydrochloride

Formule : C₂₇H₄₃Cl₂N₅O₂

Degré de pureté : 98.5%

Masse moléculaire : 540.57

Ref: 54-BUP14285

C 021 dihydrochloride

CAS : 1784252-84-1

Formule : C₂₇H₄₃Cl₂N₅O₂

Degré de pureté : 99%

Couleur et forme : Solid

Masse moléculaire : 540.5686

Ref: IN-DA01LQY9

C 021 dihydrochloride

CAS : 1784252-84-1

C 021 dihydrochloride is a chemotherapeutic drug that is used to treat cancer and inflammatory diseases. C 021 dihydrochloride has been shown to be effective in treating myeloid-derived suppressor cells (MDSCs) in a model system. It also seems to protect against the development of colon cancer and other cancers by inhibiting the growth of tumor cells through its ability to inhibit inflammatory cytokines such as c-c chemokine receptor 2 (CCR2). C 021 dihydrochloride also has regulatory effects on T-cells and leukemia cells, which may be caused by its ability to regulate the production of growth factors.

Formule : C₂₇H₄₃Cl₂N₅O₂

Degré de pureté : Min. 95%

Masse moléculaire : 540.6 g/mol

Ref: 3D-JWC25284

C-021 dihydrochloride

CAS : 1784252-84-1

C-021 dihydrochloride is a potent CCR4 antagonist. It potently inhibits functional chemotaxis in human and mouse with IC50s of 140 nM and 39 nM.

Formule : C₂₇H₄₃Cl₂N₅O₂

Degré de pureté : 98.67%

Couleur et forme : White Solid

Masse moléculaire : 540.57

Ref: TM-T10639